Silver/silver chloride nanoparticles were formed by treating mixed extracts of Capsicum frutescens and Tamarindus indica (CT) with 5 mM AgNO3 in sunlight for 120 minutes, which was confirmed by a UV-visible spectrophotometer as a comparatively sharp peak was observed at 465 nm. Crystalline properties of Ag/AgCl-NPs were examined through X-ray diffraction method. The nearly spherical shape of Ag/AgCl-NPs was confirmed by scanning electron microscopy and the average size of particle was approximately 72.2 nm. The existence of elemental Ag was assessed with an energy-dispersive spectrometer whereas two major functional groups as capping agents were obtained using Fourier transform infrared spectroscopy. The CT extract-mediated Ag/AgCl-NPs showed moderate toxicity determined against brine shrimp nauplii with an LD50 value of 177.9 μg/mL. The nanoparticles showed 92.6% growth-suppressive activity against S. aureus, 81.1% against S. boydii, 60.3% against S. dysenteriae, and 50% against E. coli at the concentration of 50 µg/ml in disc diffusion assay. The recorded free radical scavenging activities of Ag/AgCl-NPs were 55.79% at 60 µg/ml for DPPH and 64.93% at 100 µg/ml for ABTS. MTT colorimetric assay confirmed the antiproliferative activity of Ag/AgCl nanoparticles against EAC and MCF-7 cells (42.7% and 47.4%) at concentrations of 50 µg/ml and 128 µg/ml, respectively.