The risk of the aeroelastic deformation of the wings to the flight safety has become increasingly prominent for commercial transport aircraft due to the requirements for lightweight structure. In this work, Reynolds averaged Navier-Stokes (RANS) method coupled with transfinite interpolation were employed to investigate the influence of static elastic deformation of wing on aerodynamic characteristics of NASA CRM. Both bend and twist distributions were scaled in numerical simulations based on dynamic pressure, which was shown to be reasonable by the compassions between the calculations and measurements. The numerical results show premature flow separation in the middle and outboard of the wing for original configuration. Furthermore, the flow separation was supressed by the upward bending of the wing and negative twist in the leading edge, and the aerodynamic characteristics of the aircraft were improved by the aeroelastic deformation.