This study aimed to investigate the effectiveness and suitability of the integrated holistic method for teaching EFL skills embedded in an Oxford® series of courses selected for study at the lower-to-upper intermediate levels of learning EFL, namely Open Forum 3, Well Read 3 – Effective Academic Writing2. Participants of the study were selected from the population of students in a Southwestern Saudi university. The sample included 52 participants in intermediate levels. Researchers employed a pre-test, posttest control group design in a quasi-experimental method to evaluate the instructional effectiveness of the integrated holistic teaching method. Findings indicate that the treatment in this study, the Integrated Skills Treatment, had a significant effect on student performance in all skills presented instructionally according to an integrated, holistic approach. Further findings showed that the experimental group participants achieved improvements in gain scores compared with their peers in the control group on the tested language skills, namely listening and speaking, reading, and writing. Qualitative data from a follow-up questionnaire study asserted the effectiveness and appropriateness of an integrative pedagogy to teaching EFL skills. The paper, in the end, provides a set of relevant implications and recommendations for further pedagogical practice and further research implications.