Macrophomina blight disease has become a major constraint in recent years for successful and profitable cultivation of mungbean. The efficacy of different fungicides, bioagents and phytoextract in pot and field were evaluated against Macrophomina blight of mungbean. Among the foliar spray treatments (pot culture), Carbendazim 12 WP + Mancozeb 63 WP (@ 0.2%) recorded significantly highest reduction of incidence and intensity, respectively of (82.35 and 85.18%) followed by @ 0.1% Carbendazim (75.00 and 78.61%). Bioagents @ 0.5% Trichoderma harzianum (45.58 and 50.00%) and botanical @ 10% Allium sativum (41.47 and 43.64%) and Allium cepa (36.77 and 39.40%) were found effective, but B. subtilis was less effective. During Kharif, 2011–12 and 2012–2013, among the foliar spray treatments, Carbendazim 12 WP + Mancozeb 63 WP (@ 0.2%) recorded significantly least mean Macrophomina blight incidence (14.63 and 17.29%) and intensity (11.87 and 13.82%) and significantly highest mean disease reduction (67.07 and 69.17%),with significantly highest seed yield (539.63 and 535.60 kg/ha) over unsprayed control (yield 358.31 and 351.58 kg/ha), respectively and bioagents T. harzianum recorded seed yield of 484.92 and 480.52 kg/ha followed by botanicals A. sativum (470.60 and 467.29 kg/ha) and bacterial bioagent B. subtilis (432.32 and 430.52 kg/ha) recorded lowest yield among all treatments. Considering incremental cost: benefit ratio (ICBR) during Kharif, 2011–2012 and 2012–2013, the most economical treatment which recorded highest ICBR was the fungicide, Carbendazim (ICBR 1:14.83 and 1:18.38), respectively. Of the 40 mungbean cultivars/varieties evaluated (pot culture), one (BPMR-145) was found resistant. In field, during Kharif, 2011–2012 and 2012–2013, out of forty cultivars/varieties, the one cultivar BPMR-145 was found resistant and again two cultivars JL-781 and Kopargaon were found susceptible in both the year.