Effect Of Trimming Research Articles

Computational Fluid Dynamic Study of Nasal Respiratory Function Before and After Bimaxillary Orthognathic Surgery With Bone Trimming at the Inferior Edge of the Pyriform Aperture

This study aimed to evaluate the influence of maxillary impaction orthognathic surgery on nasal respiratory function and the efficacy of bone trimming at the inferior edge of the pyriform aperture. The participants were 10 patients (3 male and 7 female patients) with mandibular prognathism who underwent bimaxillary orthognathic surgery with maxillary impaction. The surgical procedures performed were Le Fort I osteotomy with bone trimming at the inferior edge of the pyriform aperture and bilateral sagittal split osteotomy. Three-dimensional models of the nasal cavity were reconstructed from preoperative and postoperative computed tomography images. Furthermore, we remodeled the nasal valve region based on the postoperative models by adding a 1-mm and 2-mm stenosis to investigate the effects of bone trimming at the inferior edge of the pyriform aperture on the pressure effort. The 3-dimensional models were simulated with computational fluid dynamics, and the results of the pressure effort and the cross-sectional area (CSA) were compared for the anterior, middle, and posterior parts of thenasal cavity. The Wilcoxon signed rank test and Spearman rank correlation coefficients were used for statistical comparisons (P < .05). In the preoperative and postoperative models, there were considerable correlations between the CSA and the pressure effort in each part of the nasal cavity. The postoperative pressure effort showed a tendency to decrease and the CSA showed a tendency to increase in each part of the nasal cavity. In four 2-mm stenosis models, the pressure effort in the anterior nasal cavity was larger than the preoperative pressure effort and the CSA of the anterior nasal cavity was smaller than the preoperative CSA. Bone trimming at the inferior edge of the pyriform aperture appears to be useful for avoiding nasal respiratory complications with maxillary impaction.

Índice produtivo e qualidade de ovos de galinhas poedeiras submetidas a diferentes métodos de debicagem

Resumo: O objetivo deste trabalho foi avaliar o efeito da debicagem, por meio de lâmina quente ou por radiação infravermelha, sobre os indicadores produtivos e de qualidade de ovos, em três linhagens de galinhas poedeiras na primeira semana de vida, e se uma segunda debicagem seria necessária na décima semana de idade. As aves foram distribuídas em um delineamento inteiramente ao acaso, em arranjo fatorial 2x3x2 (primeira debicagem por meio de radiação infravermelha ou por lâmina quente x linhagens Lohmann LSL, Hy-line W-36 e Lohmann Brown x com ou sem debicagem à décima semana de idade), no total de doze tratamentos, com seis repetições. A debicagem por radiação infravermelha, na primeira semana de vida, proporciona os mesmos resultados produtivos e de qualidade dos ovos que o método convencional por lâmina quente. Não houve mortes por canibalismo em aves das três linhagens que não foram submetidas à segunda debicagem, mas se observou decréscimo de 8% da viabilidade, em aves à 63.a semana de idade.

004 The effect of corrective claw trimming on gait analysis of the sow

004 The effect of corrective claw trimming on gait analysis of the sow

PENGARUH PEMANGKASAN DAUN BAGIAN BAWAH TERHADAP PRODUKSI JAGUNG MANIS (Zea mays var. saccharata Sturt)

The purpose of this study was to determine the effect of trimming the bottom leaves to the increased production of sweet corn crop. This research was arranged in a completely randomized design (CRD) with 4 treatments and repeated 5 times. Pruning is done at the age of 50 days after planting. The results obtained from this study are pruning significant effect on the rising corncob where the highest rates in the third pruning leaves the bottom (P3) weighing 333.04 g. In the variable length cob, cut 3 pieces (P3) gives the most high, 21.25 cm while trimming treatment 1 piece (P1) and a second piece (P2) shows the results are not significantly different from each other but significantly different from that of the untreated (P0) , While on the cob entire circumference of the variable level of treatment (P1, P2, P3) results are not significantly different from each other but all three significantly different from that of the untreated (P0) ddengan highest yield is in P3 which is 17.27 cm. from these results it can be concluded that treatment of the bottom leaf pruning can increase the production of sweet corn.

Trimming of sequence reads alters RNA-Seq gene expression estimates.

BackgroundHigh-throughput RNA-Sequencing (RNA-Seq) has become the preferred technique for studying gene expression differences between biological samples and for discovering novel isoforms, though the techniques to analyze the resulting data are still immature. One pre-processing step that is widely but heterogeneously applied is trimming, in which low quality bases, identified by the probability that they are called incorrectly, are removed. However, the impact of trimming on subsequent alignment to a genome could influence downstream analyses including gene expression estimation; we hypothesized that this might occur in an inconsistent manner across different genes, resulting in differential bias.ResultsTo assess the effects of trimming on gene expression, we generated RNA-Seq data sets from four samples of larval Drosophila melanogaster sensory neurons, and used three trimming algorithms—SolexaQA, Trimmomatic, and ConDeTri—to perform quality-based trimming across a wide range of stringencies. After aligning the reads to the D. melanogaster genome with TopHat2, we used Cuffdiff2 to compare the original, untrimmed gene expression estimates to those following trimming. With the most aggressive trimming parameters, over ten percent of genes had significant changes in their estimated expression levels. This trend was seen with two additional RNA-Seq data sets and with alternative differential expression analysis pipelines. We found that the majority of the expression changes could be mitigated by imposing a minimum length filter following trimming, suggesting that the differential gene expression was primarily being driven by spurious mapping of short reads. Slight differences with the untrimmed data set remained after length filtering, which were associated with genes with low exon numbers and high GC content. Finally, an analysis of paired RNA-seq/microarray data sets suggests that no or modest trimming results in the most biologically accurate gene expression estimates.ConclusionsWe find that aggressive quality-based trimming has a large impact on the apparent makeup of RNA-Seq-based gene expression estimates, and that short reads can have a particularly strong impact. We conclude that implementation of trimming in RNA-Seq analysis workflows warrants caution, and if used, should be used in conjunction with a minimum read length filter to minimize the introduction of unpredictable changes in expression estimates.Electronic supplementary materialThe online version of this article (doi:10.1186/s12859-016-0956-2) contains supplementary material, which is available to authorized users.

Effect of Hoof Trimming on Milk Yield in Dairy Cows with Foot Disease

Backround: Milk is produced at the cost of other metabolic processes in the body and high milk yield has been associated with lameness and claw lesions. Lameness has also been associated with a decrease in milk yield. In the past, claw disorders and lameness in dairy cattle have been an increasing problem of the modern dairy industry. Hoof trimming is performed to prevent hoof lesions and improve gait by correction and maintenance of the hoof symmetry and shape. Lameness caused by hoof disorders can be treated by correct hoof trimming. The aim of this study was to test the hypothesis that one-time claw trimming affect the milk production in dairy cattle with hoof disorders on commercial dairy farms.Materials, Methods &amp; Results: Milk yield level was examined before and after claw trimming in dairy cattle. Eighteen Holstein dairy cows were examined on a commercial dairy farm. Calving number, calving time, lactation number, lactation stage, culling date and milk yield in liters were detected from farm recording system. All cows were visual signs of claw disorders or lameness. Their hooves had not been were trimmed for several years. Trimming technique included leveling the 2 claws, aiming for symmetric bulbs. The axial and abaxial walls were both intended to be parts of the bearing surface and the 2 claws were trimmed flat and balanced with each other. The caudal two-thirds of the axial sole of both claws were sloped toward the interdigital area. All of the cows checked for hoof diseases. The period of observation spanned 45 d, starting day of claw trimming. The observation period was the lactation when the claw trimming was performed. Milk yield was performed one day before and 10, 30, and 45 days after hoof trimming. Cows that were in the mid to late lactation period were selected for the study. The mean days in milk for the group was 221.8 (150-272 days) and the mean number of calvings was 2.8 times (range: 2-5 times) before trimming.Discussion: The shape of the lactation curve is influenced by herd factors such as management and nutrition and individual factors like genetics, parity, and disease. Discrepancies in the literature with regard to the effect of lameness and claw lesions on milk yield are partly the result of these complex influences. Daily milk production of cows in the current study averaged 21 L/d, so milk weight represented approximately 3% of a cow’s body weight per milking. In this study cows were 2 to 5th lactation. Most hoof diseases are accrued around the time of calving. Hoof diseases is becomed visible on the bearing surface of the sole after 2 to 3 months such as white-line disease, sole ulcer, and hemorrhages. We assessed milk yield as the one time claw trimming performed, so any possible healing effect of claw trimming could have led to an underestimation of any negative effects of bad claw health on milk production. Cows with painful claw lesions eat less, are more reluctant to move, and might consequently produce less milk than cows without claw lesions. The significant associations between most claw disorders and increased yield in this study do not prove direct relationships. At claw trimming, the average lactation stage in first parity was 148 DIM; 25% of the cows were before 74 DIM and 25% were later than 226 DIM. After the claw trimming between days 10-30 and 10-45 were determined differences in milk yield (P &lt; 0.05; P &lt; 0.01). In conclusion, this study showed that one time hoof trimming during the lactation period changed the milk yield of the dairy cows with hoof diseases.

Leaf Trimming and High Temperature Regulation of Phytohormones and Polyamines in Creeping Bentgrass Leaves

Mowing frequencies are associated with differences in disease susceptibility of turfgrasses, but how hormones respond to mowing practices are not fully understood. Two independent growth chamber experiments were conducted to determine how leaf trimming and heat stress play a role in modulating endogenous hormones within creeping bentgrass (Agrostis stolonifera) leaf tissues. The study also aimed to evaluate whether there are hormone changes at 0, 15, and 30 minutes after leaf trimming (wounding). The effects of trimming and temperature on sod plugs of creeping bentgrass ‘Penncross’ and ‘Penn-G2’ were investigated under optimal conditions (23/20 °C day/night) and heat stress (30/25 °C day/night). Plants were 1) untrimmed and sampled by plucking at the leaf base, 2) untrimmed and sampled by cutting at 0, 15, and 30 minutes, or 3) trimmed once every 3 days. Salicylic acid (SA), jasmonic acid (JA), abscisic acid (ABA), and indole-3-acetic acid (IAA) were generally greater in untrimmed plants compared with plants trimmed every 3 days under high temperature conditions. Zeatin riboside (ZR) was lower in untrimmed plants compared with plants trimmed every 3 days. JA and gibberellic acid (GA) accumulated to greater levels in the plants after 15 and 30 minutes of sampling. Polyamines (PAs) exhibited a transient increase in putrescine (Put) due to wounding. The results demonstrate the importance of research practices that consider the timing of sampling turfgrass plants for hormone analysis, help elucidate why mowing practices may play a role in stress susceptibility, and may be applicable to various studies related to leaf wounding.

Effects of Beak Trimming, Stocking Density and Sex on Carcass Yield, Carcass Components, Plasma Glucose and Triglyceride Levels in Large White Turkeys.

This study was conducted to determine the effects of beak trimming, stocking density (D) and sex (S) on live weight (LW), carcass yield and its component, and plasma glucose (PG) and triglyceride levels in Large White turkeys. To accomplish this aims, totally 288 d old large white turkey chicks (144 in each sex) were used. Beaks of 77 male and female poults were trimmed when 8 d old with an electrical beak trimmer. The birds were fed by commercial turkey rasion. Experiment was designed as 2 × 2 × 2 factorial arrangement with 3 replications in each group. Beak trimming and stocking density did not affect live weight, carcass composition and its components. The higher LW and carcass weight observed in trimmed groups. As expected, male birds are heavier than female, and carcass percentage (CP) would be adverse. However, in this study, CP of male was higher in trimmed, in 0.25 m2/bird. (D) × sex (S) interaction had an effect on both CP and thigh weights (p<0.05). Significantly D × S was observed in LW, CP and PG. The weight of carcass and its some components were higher in male. S × D interaction had an effect on plasma glucose level (p<0.05). Triglyceride level was affected (p<0.05) by sex. Significant relationships were found between percentage of thighs (r=0.447, p<0.01) and percentage of breast (r=0.400, p<0.01). According to this study, it can be said that trimming is useful with density of 0.25 m2/bird in turkey fattening.

Effects of propeller thrust trimming on tailless unmanned aerial vehicle performance

Flight performance and longitudinal static stability are two contradictory requirements for aircraft. This is especially true for a tailless configuration, whose flight performance is traded for static stability. A new tailless gull wing configuration with propeller thrust trimming is proposed in this paper. It is expected that the propeller thrust can help to provide a nose-up pitching moment and improve the flight performance. In the present configuration, a cambered airfoil is used to increase the lift-to-drag ratio as well as the maximum lift coefficient. Two approaches are adopted to obtain the nose-up pitching moment. Firstly, the thrust line is shifted below the center of gravity to make a positive contribution to the pitching moment. Secondly, the thrust vectoring is employed to trim longitudinally instead of elevon deflection. The wind-tunnel data indicate that the lift-to-drag ratio and maximum lift coefficient increase notably with the help of propeller thrust trimming. To determine the performance benefits of the gull wing with propeller thrust trimming, a conceptual design environment of the electric-powered unmanned aerial vehicle is developed by integrating the modules of the conceptual parameters, aerodynamics, stability, propulsion, weight, performance, as well as optimization. The optimization results suggest that, compared with the two other conventional tailless configurations, the gull wing with propeller thrust trimming results in 20 and 34% endurance increase. Flight tests of a 2.5 kg built aircraft demonstrate the aerodynamic feasibility of the gull wing with propeller thrust trimming concept.

Alterations in functional thalamocortical connectivity following neonatal whisker trimming with adult regrowth.

Neonatal whisker trimming followed by adult whisker regrowth leads to higher responsiveness and altered receptive field properties of cortical neurons in corresponding layer 4 barrels. Studies of functional thalamocortical (TC) connectivity in normally reared adult rats have provided insights into how experience-dependent TC synaptic plasticity could impact the establishment of feedforward excitatory and inhibitory receptive fields. The present study employed cross-correlation analyses to investigate lasting effects of neonatal whisker trimming on functional connections between simultaneously recorded thalamic neurons and regular-spike (RS), presumed excitatory, and fast-spike (FS), presumed inhibitory, barrel neurons. We find that, as reported previously, RS and FS cells in whisker-trimmed animals fire more during the earliest phase of their whisker-evoked responses, corresponding to the arrival of TC inputs, despite a lack of change or even a slight decrease in the firing of thalamic cells that contact them. Functional connections from thalamus to cortex are stronger. The probability of finding TC-RS connections was twofold greater in trimmed animals and similar to the frequency of TC-FS connections in control and trimmed animals, the latter being unaffected by whisker trimming. Unlike control cases, trimmed RS units are more likely to receive inputs from TC units (TCUs) and have mismatched angular tuning and even weakly responsive TCUs make strong functional connections on them. Results indicate that developmentally appropriate tactile experience early in life promotes the differential thalamic engagement of excitatory and inhibitory cortical neurons that underlies normal barrel function.

Effects of Acetabular Rim Trimming on Hip Joint Contact Pressures

Background: In patients with femoroacetabular impingement (FAI), acetabular rim trimming removes the offending area of the acetabular deformity in patients with pincer-type and mixed-type FAI to improve hip joint kinematics. Although the rationale for arthroscopic acetabular rim trimming in patients with FAI is well established, the amount of rim resection has not been quantified, and the threshold at which excessive rim resection results in abnormal hip contact pressures has not been described. Purpose: To investigate the changes in contact areas, contact pressures, and peak forces within the hip joint with sequential acetabular rim trimming. Study Design: Controlled laboratory study. Methods: Six fresh-frozen, nondysplastic, human cadaveric hemipelvises were analyzed utilizing thin-film piezoresistive load sensors to measure the contact area, contact pressure, and peak force after anterosuperior acetabular rim trimming at depths of 0 mm (intact), 2 mm, 4 mm, 6 mm, and 8 mm. Each specimen was examined at 20° of extension and 60° of flexion. Analysis was performed on 2 regions of interest: the acetabular rim and the acetabular base (deep part of the acetabulum). After each experimental condition, the acetabulum was normalized with respect to the intact state to account for specimen variability. Statistical analysis was conducted through 1-way analysis of variance with post hoc Games-Howell tests. Results: At the acetabular base, there were significant increases in the contact area after 4-mm resection (60°: 169.12% ± 30.64%; P = .0138), contact pressure after 6-mm resection (60°: 292.76% ± 79.07%; P = .009), and peak force after 6-mm resection (60°: 166.00% ± 34.40%; P = .027). At the acetabular rim, there were significant decreases in the contact area after 6-mm resection (60°: 66.32% ± 18.80%; P = .0354) (20°: 65.47% ± 15.87%; P = .0127), contact pressure after 6-mm resection (60°: 50.77% ± 11.49%; P < .001) (20°: 58.01% ± 23.10%; P = .0335), and peak force after 6-mm resection (60°: 60.67% ± 9.29%; P < .001) (20°: 74.44% ± 9.84%; P = .007). Conclusion: Resecting more than 4 to 6 mm of the acetabular rim during hip arthroscopic surgery to address a pincer deformity may dramatically increase contact pressures by 3-fold at the acetabular base. The study suggests that excessive rim resection may lead to increased loads in the hip joint and may predispose to premature joint degeneration. Clinical Relevance: Resecting more than 4 to 6 mm of the acetabular rim may significantly alter hip joint biomechanics, increasing joint reactive forces and subsequent chondrolabral degeneration.

The effect of toe trimming on behavior, mobility, toe length and other indicators of welfare in tom turkeys

Society is increasingly concerned about the welfare of animals kept for food production, for this reason, invasive procedures such as toe trimming in turkeys must be studied to assess the corresponding welfare implications and to ensure such procedures are acceptable for continued use. To this end, research was conducted to evaluate the welfare effects of toe trimming on toms raised to 140 d. The study used 306 Hybrid Converter toms, half of which were toe trimmed using a Microwave Claw Processor (MCP) which group are denoted T, and half of which were sham treated but not trimmed, which group are denoted NT. Turkey behavior was observed on d 1, 3, 5, and 133. Toe cross sections were taken every second day for 14 d after treatment and were used to histologically examine the healing process. Toe length, gait score, and bird stance were assessed on d 55, 84, 119, and 139. For the first 5 d after treatment, T birds demonstrated less active behaviors such as feeding, standing, walking and running (P ≤ 0.05), indicative of pain with the effect diminishing with age. At d 133, T turkeys stood more and walked less than NT birds (P ≤ 0.05). Gait score and bird stance were not affected by treatment. Trimmed toes were on average 91.9% of the length of NT toes and toe length was more variable (P ≤ 0.05) as a result of the trimming process. Histological examination indicated T toes had complete epithelium closure over the healthy tissue by d 8 and were fully healed by d 14. Although bird mobility and stance were unaffected by treatment, turkey behavior both early and late in the production cycle were suggestive of pain and balance effects; both indicators of reduced welfare as a result of toe trimming.

Effect of early lactation foot trimming in lame and non-lame dairy heifers: a randomised controlled trial

Foot trimming is a common management intervention in prevention of lameness in dairy cattle. Despite this, there is surprisingly limited experimental evidence on its efficacy, especially in regard to primiparous...

Effects of Acetabular Rim Trimming on the Hip Joint Contact Pressure: How Much is Too Much?

Effects of Acetabular Rim Trimming on the Hip Joint Contact Pressure: How Much is Too Much?

Effect of partial comb and wattle trim on pullet behavior and thermoregulation,

The wattles and comb of chickens are important for thermoregulation allowing for heat exchange during high temperatures. These integumentary tissues are sometimes trimmed to prevent tears if caught on cage equipment and to also improve feed efficiency; however, the procedure itself could be painful to chicks. Our objective was to determine the effect of trimming the comb and wattles on behavior, BW, feed usage, and the surface temperature of pullets. The wattles and comb of Leghorns were partially trimmed at 21 d age (n = 6 cages, 13 chicks each) with another 6 cages serving as controls. Behaviors were recorded 3 times daily for 1 h starting at 0800, 1200, and 1500 using instantaneous scan sampling observations conducted every 5 min prior to, on the d of, and after the trim. Group BW at 21, 28, and 36 d age and the amount of feed used for 7 d beginning at 21 and 29 d age were measured per cage. At 1300 h on d before and after the trim, thermal images of the pullet's beak, comb, eye, wattle, and shank were randomly taken on 3 pullets/cage. Smaller proportions of trimmed chicks were eating and greater proportions were sitting on the d of the trim as compared to the controls with the opposite trend occurring on 4 d post-trim (treatment by age interaction, P = 0.03 and 0.0001, respectively). Standing behavior differed only on the d of the trim where smaller proportions of trimmed pullets stood as compared to intact controls (treatment by age interaction, P = 0.0002). Trimming the comb and wattles did not affect preening, running, BW, feed utilization, and the surface temperature of the pullet. The indices of behavior suggest that on the d of the trim, pullets may have experienced temporary distress, but they returned to normal behavior by 5 h post-trim with no long-term effect on BW, feed usage, or surface body temperature.

Effects of Acetabular Rim Trimming on Hip Joint Contact Pressure

Objectives:In patients with femoroacetabular impingement (FAI), acetabular rim trimming removes the offending cause of pain in patients with pincer-type and mixed-pincer-cam type pathology and helps protect repaired damaged labrum from further injury. Although the clinical benefit of arthroscopic acetabular rim trimming in FAI patients is well established, the threshold at which excessive rim resection results in abnormal hip contact pressures from iatrogenic acetabular dysplasia has never been studied. The purpose of the present study was to investigate the changes in contact areas, contact pressures and peak forces within the hip joint with sequential acetabular rim-trimming.Methods:A comparative biomechanical analysis of 4 fresh-frozen human cadaver hemi-pelvises was performed. Prior to testing, all specimens underwent a CT scan and were deemed non-dysplastic based on center edge angle measurements. For each specimen, the acetabulum and proximal femur were potted in dental cement and mounted on a materials testing system (MTS Insight 5, Eden Prairie, MN). After resecting the labrum, a contact pressure and area mapping system (Tekscan, Boston MA) was placed within the acetabulum and a 700 N load was subsequently applied resulting in a real-time pressure map. Each specimen was sequentially tested in the intact state as well as anterosuperior acetabular rim-trimming (from the 12 o’clock to 3 o’clock position) of 2mm, 4mm, 6mm and 8mm depth. Each testing condition was examined at two different positions within the natural hip range of motion: 20° extension and 60° flexion. Analysis of total force, contact area, contact pressure and peak force was performed on two regions of interest: the acetabular rim and the acetabular base (deep part of acetabulum). The rim-trimmed states were then normalized with respect to the intact state in order to help account for specimen variability. Statistical analysis was conducted via a Paired and Unpaired Student’s T-test on normalized data.Results:At 60° flexion, rim-trim depth was significantly correlated to acetabular rim contact area (R=-0.698, P=0.001), contact pressure (R=-0.892, P<0.001) and peak force (R=-0.857, P<0.001). At 20° extension, rim-trim depth was significantly correlated to acetabular rim contact area (R=-0.684, P=0.001), contact pressure (R=-0.673, P=0.001) and peak force (R=-0.574, P=0.008). With regards to the acetabular base, at 60° flexion and 6mm resection there was a statistically significant increase in both base contact pressure (393.90%±163.33, P=0.020) and base peak force (178.94%±75.7, P=0.026). There was also a significant increase in base contact area after 8mm resection at 60° flexion (408.15%±224.17, P=0.015). At 60° flexion, rim-trim depth was significantly correlated to acetabular base contact area (R=0.604, P=0.005), contact pressure (R=0.718, P<0.001) and peek force (R=0.593, P=0.006).Conclusion:Resecting more than 4-6 mm of bone in an acetabular rim trimming hip arthroscopy procedure may dramatically increase hip joint contact pressures and predispose patients to early osteoarthritis via creation of an iatrogenic acetabular dysplasia. In dysplastic or borderline dysplastic hips, the amount of safe resection may be even less.

Effect of routine claw trimming on claw temperature in dairy cows measured by infrared thermography

Infrared thermography (IRT) was used to assess the effect of routine claw trimming on claw temperature. In total, 648 IRT observations each were collected from 81 cows housed in 6 tiestalls before and 3wk after claw trimming. The feet were classified as either healthy (nonlesion group, n=182) or affected with infectious foot disorders (group IFD, n=142). The maximal surface temperatures of the coronary band and skin and the difference of the maximal temperatures (ΔT) between the lateral and medial claws of the respective foot were assessed. Linear mixed models, correcting for the hierarchical structure of the data, ambient temperature, and infectious status of the claws, were developed to evaluate the effect of time in relation to the trimming event (d 0 versus d 21) and claw (medial versus lateral). Front feet and hind feet were analyzed separately. Ambient temperature and infectious foot status were identified as external and internal factors, respectively, that significantly affected claw temperature. Before claw trimming, the lateral claws of the hind feet were significantly warmer compared with the medial claws, whereas such a difference was not evident for the claws of the front feet. At d 21, ΔT of the hind feet was reduced by ≥0.25°C, whereas it was increased by ≤0.13°C in the front feet compared with d 0. Therefore, trimming was associated with a remarkable decrease of ΔT of the hind claws. Equalizing the weight bearing of the hind feet by routine claw trimming is associated with a measurable reduction of ΔT between the paired hind claws.

The Effect of Trimming and Sinkage on the Trimaran Resistance Calculation

The clam water resistance as well as the resistance components of a trimaran test model with and without appendage is calculated by CFD method in the different conditions, taking viscous effect and the free surface into account, in order to investigate the effect of trimming and sinkage on the resistance calculation. The viscous flow field around the trimaran without appendage restrained and free in 6 degrees of freedom is simulated at different velocities, the numerical results of the free model are compared with the test data and show good agreement. The total resistance and the resistance of the main hull, as well as the outriggers are calculated and the details of the flow field are discussed. Then, the numerical results of the free model and the captive model are compared in order to analyse the effect of trimming and sinkage. The analysis of the comparison suggests that some of the resistance components are susceptible to the gesture. After that, the viscous flow field of the trimaran with T-foil is simulated and the total resistance, resistance components as well as the gesture are calculated. The comparison of the numerical results of the free model with T-foil and the experimental data also shows good agreement, and the details of viscous flow field as well as the resistance components are analyzed.

In Vivo Proliferation of In Vitro Propagated Sugarcane (Saccharum officinarum L.) genotypes at Tana- Beles Sugar Development Project, North-Western Ethiopia

In spite of the costly procurement and secondary acclimatization activities, the Ethiopia Sugar estates use huge quantity of micropropagated sugarcane plantlets to complement the conventional propagation method. The current study was aimed at finding rapid and cost effective propagation method for sugarcane planting materials multiplication to complement in vitro propagation method. In the study, acclimatized sugarcane plantlets were treated with Diammonium phosphate fertilizer (DAP), plant growth regulators and leaf trimming treatments. Plantlets lacking fertilizer, plant growth regulators and without trimming were used as free check. Data were collected on the number of tillers per shoot, average shoot length and number of leaves per shoot after 30 days. Analysis of variance revealed that the interaction effects of genotypes, trimming, DAP and plant growth regulators application was very highly significant (p<0.0001). Treatment combinations containing DAP at 0.16 gm L-1 m-2 with plant growth regulators GA3, BAP and kinetin each at 0.04 mg L-1 m-2 and trimming one-third of the leaves gave optimum in vivo shoot proliferation responses. On this treatment combination, B52-298 gave 6.45 ± 0.51 tillers per shoot with 4.39 ± 1.44 cm average shoot length and 5.12 ± 0.23 leaves per shoot while NCo-334 produced 5.77± 0.79 tillers per shoot with 7.21 ± 0.11 cm average shoot length and 5.51 ± 0.05 leaves per shoot. Similarly, N14 gave 5.36 ± 0.55 tillers per shoot with 5.71 ± 0.15 cm average shoot length and 5.41 ± 0.30 leaves per shoot on the same treatment combination. Thus, the current result can be used as rapid and cost effective sugarcane planting material multiplication system to complement the costly micropropagation technology and hence minimize the cost of sugar production.

CREB Regulates Experience-Dependent Spine Formation and Enlargement in Mouse Barrel Cortex.

Experience modifies synaptic connectivity through processes that involve dendritic spine rearrangements in neuronal circuits. Although cAMP response element binding protein (CREB) has a key function in spines changes, its role in activity-dependent rearrangements in brain regions of rodents interacting with the surrounding environment has received little attention so far. Here we studied the effects of vibrissae trimming, a widely used model of sensory deprivation-induced cortical plasticity, on processes associated with dendritic spine rearrangements in the barrel cortex of a transgenic mouse model of CREB downregulation (mCREB mice). We found that sensory deprivation through prolonged whisker trimming leads to an increased number of thin spines in the layer V of related barrel cortex (Contra) in wild type but not mCREB mice. In the barrel field controlling spared whiskers (Ipsi), the same trimming protocol results in a CREB-dependent enlargement of dendritic spines. Last, we demonstrated that CREB regulates structural rearrangements of synapses that associate with dynamic changes of dendritic spines. Our findings suggest that CREB plays a key role in dendritic spine dynamics and synaptic circuits rearrangements that account for new brain connectivity in response to changes in the environment.