A Middling quality of concrete exacerbates deterioration that tarnishes structural integrity and leads to dilapidated infrastructures. The significant intent of this work is to develop sustainable Ultra-High-Performance Concrete (UHPC) using nanosilica and nano clay. The factors, such as particle size, shape, and particle packing effect plays a key role in development of eco-friendly UHPC. Elkem Materials Mixture Analyser (EMMA), based on Modified Andreasen and Andersen particle packing theory is employed for mix optimization to attain dense packing with low binder content. UHPC is amalgamated with cement, silica fume, nanosilica, and nano clay in various combinations. The mix combination includes control mix (A0), B1–B3 that holds 1–3% nano silica, and C1–C3 yields 1–3% nano clay. It is inferred, B3 (3% nanosilica) exhibits the highest compressive strength of 118 MPa due to its size, quasi spherical shape, and homogenous dispersion. Consequently, C2 (2% nanoclay) manifest 18 and 33% enhancement in splitting tensile and modulus of rupture due to due to layered shape of nano clay that acts as reinforcement, inhibits cracks, and improves strength Microstructural analysis confirms the formation of additional hydration products with less voids. Thus, synergy of particle size, shape, and packing effect results in sustainable UHPC.