Effect Of Media Research Articles

Anticancer Effect of Cycas media: Molecular Basis Through Modulation of PI3K/AKT/mTOR Signaling Pathway.

Many researchers are focusing on screening the biological activities of plants owing to their safety and possible pharmacological actions. Consequently, we aimed to explore the antiproliferative and cytotoxic properties of Cycas media methanolic extract on HepG2 cell lines. Moreover, we also explore the antitumor action against the experimentally induced solid Ehrlich carcinoma (SEC) model and investigate the possible involved molecular mechanisms. Also, the antibacterial action of the extract was elucidated. Different concentrations of the extract were incubated with HepG2 to determine cytotoxicity, followed by cell cycle analysis. The in vivo experiment was accomplished by grouping the animals into four different groups (n = 10); normal control, SEC, C. media 100, and C. media 200. The extract was administered at 100 and 200 mg/kg. Tumor volume, tumor inhibition rate, toxicity profile, and antioxidant biomarkers were determined. Moreover, the PI3K/AKT/mTOR signaling pathway was investigated as a possible underlying antitumor mechanism. The tumor control group showed a remarkable upregulation for PI3K, p-AKT, and p-mTOR, along with downregulation for the antioxidant SOD and GPX4, as well as decreased levels of GSH and MDA. C. media extract reversed these parameters to a significant level and the higher dose showed a superior antitumor effect. C. media extract showed antiproliferative effects against HepG2 cells, along with a suppressive action on the PI3K/AKT/mTOR pathway and an antioxidant effect. Additionally, C. media had antibacterial consequences against S. aureus isolates with minimum inhibitory concentrations from 32 to 128 µg/mL. It also caused a noteworthy growth delay as well as a notable reduction in the membrane integrity of S. aureus isolates. These beneficial outcomes suggest C. media to have potential antitumor and antibacterial activities.

Exploring the Impact of Handwriting vs. Keyboarding on L2 Assessments: Biases, Integrity, Authenticity, and Literacies

Is paper or computer better for assessing L2 students’ writing? The ineluctable transition to technology might suggest this question has already been answered. However, the technology divide in L2 assessments may have indeed widened since the pandemic: whereas some teachers have fully embraced technology in assessments as in instruction, others are reluctant to eliminate paper, owing to concerns about the reliability, integrity and authenticity of L2 production on computer. This article shares observations from several French classes at an American high school in which assessments that were otherwise identical were offered to students on both paper and computer. These observations revealed several overlapping areas of L2 research that merit further consideration, including instructor bias between media, academic integrity of student work, and the need to align the technological literacies between instructors and students. The reflection that follows points to specific directions for further empirical research on the effects of input medium on L2 learners in K-12 and higher education.

A Person-Based Web-Based Sleep Intervention Aimed at Adolescents (SleepWise): Randomized Controlled Feasibility Study.

Adolescents are advised to sleep 8-10 hours per night; however, most do not sleep for this recommended amount. Poor adolescent sleep is associated with detrimental health outcomes, including reduced physical activity, risk-taking behaviors, and increased depression and anxiety levels, making this an important public health concern. Existing interventions targeting adolescent sleep are often unsuccessful or their effectiveness unclear, as they are frequently noninteractive, time-consuming, and lack a strong theoretical foundation; highlighting an urgent need for innovative interventions deemed acceptable by adolescents. The main objective of this study was to determine the acceptability, feasibility, and preliminary impact of a web-based person-based sleep intervention (SleepWise) on adolescent sleep quality. Participant incentivization was also explored to understand its impact on engagement, acceptability, and sleep quality. A feasibility trial was conducted to test the feasibility, acceptability, and preliminary impact of SleepWise on adolescent sleep quality, developed based on the person-based approach to intervention development. In total, 90 participants (aged 13-17 years) from further education institutions and secondary schools were recruited for two 2-arm randomized controlled trials. One trial (trial 1) was incentivized to understand the impact of incentivization. Acceptability and sleep quality were assessed via questionnaires, and a mixed methods process evaluation was undertaken to assess participant engagement and experience with SleepWise. Engagement was automatically tracked by SleepWise, which collected data on the date and time, pages viewed, and the number of goals and sleep logs completed per participant. Semistructured interviews were carried out to gain participant feedback. Participants in both trials reported high levels of acceptability (trial 1: mean 21.00, SD 2.74; trial 2: mean 20.82, SD 2.48) and demonstrated similar levels of engagement with SleepWise. Participants in trial 1 viewed slightly more pages of the intervention, and those in trial 2 achieved their set goals more frequently. Improvements in sleep quality were found in both trials 1 and 2, with medium (trial 1) and large (trial 2) effect sizes. A larger effect size for improvement in sleep quality was found in the nonincentivized trial (d=0.87), suggesting that incentivization may not impact engagement or sleep quality. Both trials achieved acceptable recruitment (trial 1, N=48; trial 2, N=42), and retention at 5 weeks (trial 1: N=30; trial 2: N=30). Qualitative findings showed that adolescents lead busy lifestyles, which may hinder engagement; however, participants deemed SleepWise acceptable in length and content, and made attempts at behavior change. SleepWise is an acceptable and potentially efficacious web-based sleep intervention aimed at adolescents. Findings from this study showed that incentivization did not greatly impact engagement, acceptability, or sleep quality. Subject to a full trial, SleepWise has the potential to address the urgent need for innovative, personalized, and acceptable sleep interventions for adolescents. OSF Registries osf.io/yanb2; https://osf.io/yanb2.

Genetic Prediction Modeling in Large Cohort Studies via Boosting Targeted Loss Functions.

Polygenic risk scores (PRS) aim to predict a trait from genetic information, relying on common genetic variants with low to medium effect sizes. As genotype data are high-dimensional in nature, it is crucial to develop methods that can be applied to large-scale data (large and large ). Many PRS tools aggregate univariate summary statistics from genome-wide association studies into a single score. Recent advancements allow simultaneous modeling of variant effects from individual-level genotype data. In this context, we introduced snpboost, an algorithm that applies statistical boosting on individual-level genotype data to estimate PRS via multivariable regression models. By processing variants iteratively in batches, snpboost can deal with large-scale cohort data. Having solved the technical obstacles due to data dimensionality, the methodological scope can now be broadened-focusing on key objectives for the clinical application of PRS. Similar to most methods in this context, snpboost has, so far, been restricted to quantitative and binary traits. Now, we incorporate more advanced alternatives-targeted to the particular aim and outcome. Adapting the loss function extends the snpboost framework to further data situations such as time-to-event and count data. Furthermore, alternative loss functions for continuous outcomes allow us to focus not only on the mean of the conditional distribution but also on other aspects that may be more helpful in the risk stratification of individual patients and can quantify prediction uncertainty, for example, median or quantile regression. This work enhances PRS fitting across multiple model classes previously unfeasible for this data type.

The Role of Household Social Support and Undermining in Dietary Change.

US adults find it challenging to meet disease prevention dietary recommendations and may participate in interventions to improve dietary quality. Social influences outside of the intervention, including level of social support and undermining of healthy eating in the home, may affect an individual's dietary intake. This secondary analysis examined (1) changes in household social support and undermining of healthy eating across a dietary intervention with household member participation and (2) the relationship between changes in social influences and dietary intake. Adults (N = 62) with low adherence to cancer prevention dietary recommendations recruited from the Philadelphia area participated in a 20-week dietary intervention focused on psychoeducation about NCI dietary recommendations and skills for behavior change. Half of the participants were also randomized to have an adult household member participate in some intervention contacts with them. Participants completed measures of social support and undermining of healthy eating and dietary intake at baseline and post-treatment (20weeks). Fifty-two participants had available data for baseline and post-treatment (i.e., completers). Household social support of healthy eating increased more among participants randomized to have household involvement in the intervention with a medium effect (η2 = .11). Fruit and vegetable intake significantly increased among participants with meaningful increases in household social support with a large effect (η2 = .37). There were no significant interaction effects of change in household undermining and time on change in dietary intake. Dietary interventions with a household support component show promise for improving household social support and may impact magnitude of dietary change.

Investigating the impact of three levels of representation-based visual media on students’ mental models

Abstract This study examines the effect of visual media on students’ mental models regarding battery functions and electrical resistance concepts. The study presents a novel visual media approach consisting of phenomena videos, dynamic analogies, and microscopic models. The development of the visual media followed the ADDIE model. The research subjects were 25 12th-grade students from a private senior high school in Bandung, West Java. Students’ mental models were assessed using open-ended test that examined four concepts: (1) electromotive force (EMF) in batteries; (2) electrical resistance; (3) resistors in series; and (4) resistors in parallel. The test were administered as both pre-tests and post-tests.The pre-test results revealed that the majority of students had initial mental models regarding battery functions and electrical resistance concepts. By the end of the study, most students had developed synthetic mental models. However, the majority successfully achieved scientific mental models concerning electrical resistance concepts. In other concepts, only a few students achieved scientific mental models. Overall, the visual media had a significant positive effect on students’ mental models, with corrections observed in 92% of students for EMF in batteries, 96% for electrical resistance, 80% for resistors in series, and 84% for resistors in parallel.These findings encourage physics teachers and researchers to develop innovative visual media focused on correcting students’ mental models in scientific concept learning.

An asymmetrical reinforcing spiral? Disentangling the longitudinal dynamics of media use and mainstream media trust

Abstract While numerous studies have documented an association between mainstream media trust and mainstream media use, only little is known about potential causal mechanisms underlying the association. We theorize that selective exposure, social influence, and the reinforcing spirals model offer three possible mechanisms that may underlie the association. These possibilities were studied using random intercept cross-lagged panel models and latent curve models on a four-wave panel data set (n = 3,540). For mainstream media, the results show an asymmetrical reinforcing spiral, in which the effect of mainstream media trust on use can be considered as one of yielding maintenance, while the impact of media use on mainstream media trust to a limited degree is in line with the notion of a spiral gradually (though inconsistently) increasing trust over time. We also find that use of right-wing alternative media consistently and sometimes robustly leads to decreasing mainstream media trust.

Effect of CTAB and NaBH4 Solutions on Ti and Cu Nanoparticles Prepared by Pulsed Laser Ablation

The effect of different media, including cetyltrimethylammonium bromide (CTAB) and sodium borohydride (NaBH4), on the size, shape, optical absorption, and stability of titanium (Ti) and copper (Cu) nanoparticles (NPs) synthesized by laser ablation in liquid, was investigated. Ti and Cu NPs were fabricated by irradiating Ti and Cu targets using a Nd:YAG pulsed laser with a wavelength of 1064 nm, an energy of 500 mJ, repetition rate of 1 Hz, and a number of pulses of 1000. Results showed the direct effect of the type of surfactant on the size and size distribution of Ti and Cu NPs under the same laser ablation parameters. Morphological properties were described by field emission scanning electron microscope (FESEM) images, which revealed the formation of semispherical particles. The EDS results confirmed the spike-induced synthesis of Ti and Cu in CTAB and NaBH4 solutions. The transmission electron microscopy (TEM) images showed the nanostructures of Ti and Cu with spherical particles. The UV-vis absorption spectra showed that the absorption peak of Ti was almost constant at 289 nm, while the peak of Cu disappeared for both solutions. Zeta potential analysis showed that NPs prepared in CTAB solution were more stable than those in NaBH4 solution.

Efektivitas Penggunaan Media Interaktif Berbantuan Quizizz Paper Mode Terhadap Hasil Belajar Siswa pada Mata Pelajaran Tematik Kelas IV SD Sederajat

This study aims to determine the effectiveness of interactive media assisted by quizizz paper mode on student learning outcomes in Thematic Subjects in grade IV elementary school equivalent. This study uses a quantitative approach with the Quasy Experiment type of research. The design of this study uses a type of one group pretest-posttest design. The population in this study is grade IV elementary school students equivalent to sampling using the Purposive Sampling technique. At SDN 01 Koto Tangah Simalanggang with a total of 20 students. The data collection technique is carried out by, namely first conducting an initial test, providing treatment, final test and documentation. The data analysis technique was carried out by comparing pretest and posttest scores using the Wilcoxon Test. The results of the study showed an average score of 70.55 for the pretest while an average score of 83.9 for the posttest. So the data obtained will be analyzed using the Wilcoxon test with decision making if the value of Asymp.sig < 0.05, then the hypothesis is accepted, if the value of Asymp.Sig > 0.05, then the hypothesis is rejected. Based on the output of "Test Statistics", it is known that Asymp.Sig (2-tailed) is worth 0.000. Because the value of 0.000 < 0.05 can be concluded that "Hypothesis Accepted" means that there is a difference between the learning outcomes for the pretest and posttest. So it can be concluded that the use of interactive media assisted by paper mode is effective in improving student learning outcomes

Meta-analysis: Correlation between academic stress and sleep quality in urban living

Purpose: Sleep quality is essential because it is associated with quality of life. It plays a vital role in good health and well-being throughout life. This study aims to see whether there is a correlation between academic stress and sleep quality among urban students. Method: This research uses a meta-analysis research method. This meta-analysis research uses 15 article of literature (2012-2024). Result: Based on the results of the meta-analysis, it can be seen that there was an effect size correlation between academic stress and sleep quality, which was classified into a medium effect size (r=0.454, p=<0.001, 95% CI=-0.288 – 0.619). Conclusion: So it can be concluded that there is a significant relationship between academic stress and sleep quality. This research highlights the importance of managing time to minimize academic stress affecting sleep patterns.

NAMAH—An Innovative Tele-ECHO Mentoring Program to Foster Well-being Among Physicians

Background: The current study aimed to develop and implement the National Assistance in Mental Health for Health Care Providers (NAMAH) module, which focused on wellness and building resilience for a cohort of physicians. Methods: The NAMAH module is a 12-week tele-mentoring program leveraging videoconference technology that uses the ECHO (Extension of Community Healthcare Outcome) HUB and SPOKE and consists of real-life case discussions and a brief didactic. The module’s content was developed after iterative feedback from experts and incorporated suggestions from healthcare providers (HCPs) following a needs assessment. A pre and post-design was used to assess the impact of the module on psychological distress using the self-reported Kessler Psychological Distress Scale (K10) and burnout using the Maslach Burnout—Inventory-Human Services Survey (MBI-HSS) among the 32 physicians who participated. Results: There was a significant decrease in the mean scores before (19.5 ± 6.27) and after (17.38 ± 6.23) the NAMAH module ( p < .05) in the psychological distress as measured by K 10 with a Cohen’s d of 0.41 (95% CI: 0.05–0.77). There was also a significant decrease in the mean scores after the intervention in the emotional exhaustion and depersonalization domain of the MBI-HSS with a medium effect size (Cohen’s d of 0.65) and large effect size (Cohen’s d of 0.94), respectively. Conclusion: The findings from this pilot study lay a foundational framework, encouraging further exploration, research, and scaling-up of such interventions to enhance mental health among physicians and HCPs.

Development of HTML5-Based Mobile Learning Media to Enhance Critical Thinking Skills of Elementary School Students in IPAS Learning

This study aims to examine the validity, practicality, and effectiveness of HTML5-based mobile learning media to enhance the critical thinking skills of elementary school students in science learning (IPAS). The research method used was Research and Development (R&D) with the ADDIE model (analysis, design, development, implementation, evaluation). The study subjects were fourth-grade elementary students from two schools, SDN Yosowilangun Kidul 01 and SDN Yosowilangun Kidul 03 in Lumajang Regency. Data collection techniques included questionnaires, expert validation instruments, practicality instruments, and pretest-posttest data. Data analysis was conducted using a descriptive quantitative approach, focusing on student needs and the validity, practicality, and effectiveness of HTML5-based mobile learning media. The results showed that the HTML5-based mobile learning media had an average validity score of 88.9%, categorized as "highly valid." The practicality test, based on teacher observation and student response questionnaires, yielded an average percentage of 91.50%, categorized as "very practical," indicating that the media is suitable for use in the learning process. In the effectiveness test, the analysis of critical thinking data resulted in an N-gain score of 0.754, categorized as "high," demonstrating that the use of HTML5-based mobile learning media can significantly improve students' critical thinking skills in elementary science learning. In conclusion, the use of HTML5-based mobile learning media in science learning is valid, feasible, and highly effective for improving students' learning outcomes and critical thinking skills at the elementary level.

Effect of Media on Lablab (Lablab purpureus var. typicus) for Yield and Quality under Soilless Vertical Farming System

Background: Lablab (Lablab purpureus var. typicus) is one of the important leguminous vegetable crops known for its highest content of protein. The area under cultivation is shrinking due to conversion of farm land into non-agricultural purposes. Under these circumstances, soilless vertical farming system is the only alternate cultivation system for increasing production of vegetables. Media play a major role in growth and yield of vegetables under soilless conditions. With this background, the present experiment was carried out to study the effect of growing media in lablab for high yield and quality under soilless vertical farming systems. Methods: Two lablab varieties viz., CO 5 (V1) and Arka Prasidhi (V2) were raised under five different media combinations viz., 100% cocopeat (M1), 50 % cocopeat + 50 % Vermicompost (M2), 50% cocopeat + 50 % FYM (M3), 50% cocopeat + 25% vermicompost + 25% FYM (M4) and Control (M5) with three replications during 2021-2022 and 2022-2023. This experiment was laid out in FCRD. The growth and yield parameters were recorded and the data was subjected to statistical analysis. Result: The experimental results revealed that both the varieties and growing media provided significant impact on growth, yield, quality and uptake of nutrients whereas dry matter content exhibited no significant impact among the different media. The pooled season data revealed that variety CO 5 observed for the overall superior performance while the media combination of 50% cocopeat + 50% Vermicompost considered superior for growth and yield characters where 50% cocopeat + 25% vermicompost + 25% FYM showed superiority for the quality parameters and uptake of nutrients.

Psilocybin-assisted neurofeedback for the improvement of executive functions: a randomized semi-naturalistic-lab feasibility study.

Executive function deficits, common in psychiatric disorders, hinder daily activities and may be linked to diminished neural plasticity, affecting treatment and training responsiveness. In this pioneering study, we evaluated the feasibility and preliminary efficacy of psilocybin-assisted frontal-midline theta neurofeedback (NF), a neuromodulation technique leveraging neuroplasticity, to improve executive functions (EFs). Thirty-seven eligible participants were randomized into an experimental group (n = 18) and a passive control group (n = 19). The experimental group underwent three microdose sessions and then three psilocybin-assisted NF sessions, without requiring psychological support, demonstrating the approach's feasibility. NF learning showed a statistical trend for increases in frontal-midline theta from session to session with a large effect size and non-significant but medium effect size dynamical changes within sessions. Placebo effects were consistent across groups, with no tasks-based EF improvements, but significant self-reported gains in daily EFs-working memory, shifting, monitoring and inhibition-showing medium and high effect sizes. The experimental group's significant gains in their key training goals underscored the approach's external relevance. A thorough study with regular sessions and an active control group is crucial to evaluate EFs improvement and their specificity in future. Psilocybin-enhanced NF could offer significant, lasting benefits across diagnoses, improving daily functioning. This article is part of the theme issue 'Neurofeedback: new territories and neurocognitive mechanisms of endogenous neuromodulation'.

PUBLIC PARTICIPATION MECHANISM IN LOW-CARBON TRANSPORTATION FROM THE PERSPECTIVE OF CARBON NEUTRALITY

Under the goal of carbon neutrality, public participation in green travel is the fundamental premise of low-carbon transportation development. Based on the multiple mediation effect model, this paper explores the mechanism of social interaction on public participation in low-carbon transportation, and the hierarchical regression method is used to test the moderating effect of social network intensity and information network intensity. The results show that: (1) Both network media and social relations have a prominent positive effect on public participation, but the effect of network media is better than that of social relations. (2) Network media and social relations affect residents’ low-carbon travel behavior through three mediating variables, namely, traffic information, environmental protection knowledge and social norms. (3) The moderating effect of social network intensity on the relationship between network media and low-carbon travel behavior is prominently negative, while the moderating effect of information network intensity is significantly positive. Therefore, it is necessary to stimulate more public participation in low-carbon transport through real-time pushing of traffic information and strengthening the closeness of social relations.

An Analytical Analysis of Mixed Convective MHD Casson Flow with Ramped Wall Temperature

This research discusses the behavior of magnetohydrodynamic Casson fluid subjected to a ramped wall temperature along an infinitely inclined plate. Non-Newtonian fluid, specifically the Casson fluid, is employed to characterize fluid behavior in this research. The effects of porous media, chemical reactions, and radiation are considered. In practical applications, non-Newtonian fluids find use in lubrication such as grease, engine oil, etc. The Laplace transform technique has been applied during this study where ordinary differential equations are converted from the governing partial differential equations with suitable boundary conditions. These transformed dimensionless equations are subsequently solved numerically with Mathematica, and we have achieved the exact solutions of momentum, followed by energy and finally concentration. In the results section, we have analyzed the behavior of flow features under varying conditions of key parameters, including the governing parameters, the unsteadiness parameter, and the Casson parameter. All the results are shown and analyzed in graphs.

Anti-tumor effects of ellagic acid and mesenchymal stem cell-conditioned medium on breast cancer cells on the 3D printed PCL/agarose scaffolds

Numerous investigations have demonstrated that natural bioactive compounds, such as flavonoids, exhibit synergistic effects with anticancer agents utilized in clinical practice. Stem cell therapies play a critical role in the domain of oncology; nevertheless, conflicting results have surfaced regarding the potential pro-cancer or anti-cancer characteristics of mesenchymal stem cells. The primary aim of the current investigation was to examine the anticancer efficacy of ellagic acid (EA) alone or in combination with adipose tissue stem cells derived conditioned medium (ADSCs-CM) on human breast cancer cells. In order to overcome the potential effects of two-dimensional (2D) culture, a three-dimensional (3D) printed polycaprolactone (PCL)/agarose scaffold is utilized to evaluate cancer cell behavior. More recently it was reported this scaffold had open and interconnected pores, as well as good water absorption and mechanical properties. Assessment of MCF-7 cancer cell viability was conducted through MTT assay, flow cytometry, cell cycle assay, and quantitative real-time PCR within a 3D cell culture framework. The outcomes revealed a reduction in cancer cell viability across all treatment cohorts in comparison to the control group. Particularly noteworthy was the significantly enhanced effect of the EA and CM combination relative to each component administered individually. Flow cytometry assessment using annexin V/PI staining indicated a decrease in cancer cells, particularly evident in the combination-treated group. Furthermore, the mRNA expression levels of BAX, BCL2, vascular endothelial growth factor (VEGF), and caspase 3 genes were consistent with pathways associated with apoptosis. Consequently, the synergistic anti-proliferative impact of EA in conjunction with ADSCs-CM on MCF-7 cells has been substantiated. These findings have two important implications for breast cancer research; highlight the utility of the PCL/agarose scaffold as a cancer model and suggest new avenues for the development of adjuvant anticancer therapeutic approaches.

Deep Traces of Social Media: A Study on its Economic and Psyshological Effects

The rapid spread of social media platforms has deeply affected modern societies and led to significant changes in economic and psychological fields. This article aims to examine the deep traces of this phenomenon by focusing on the economic effects and psychological consequences of social media. It covers topics such as the economic effects of social media, its effects on consumer behavior, the transformation of advertising and commerce, as well as revenue models and innovations in the business world. In particular, the development of digital marketing strategies, brand awareness creation processes and their effects on businesses' customer relationship management were examined. In terms of psychological effects, the effects of social media on individuals, social connections, self-perception and psychological health are discussed. New psychological conditions such as loneliness, anxiety, social comparison and digital fatigue are among the problems that arise with the widespread use of social media. This article provides a critical review to understand the complex effects of social media on today's societies and lay the foundation for future research.

Systematic review synthesising the effects of study abroad experience on the development of language fluency

ABSTRACT Given the importance of learning contexts in second language (L2) learning, study abroad (SA) has received due attention in the L2 literature, as this context has been proposed to accelerate L2 development. In line with recent efforts to synthesise the effects of SA on L2 learning, the present study reports a meta-analysis of the effects of SA experience on the development of L2 fluency compared to the at-home environment. Our dataset comprised 14 between-group studies, all based on quasi-experimental designs, including a comparison group. The results indicate that the SA context had an overall medium effect (Hedges’ g = 0.65, SE = 0.10, 95% CI [0.44, 0.87]) on the development of L2 fluency compared to its at-home counterpart. We also identified several variables related to learner characteristics and SA programme features and further examined their moderating effects on SA. Based on our findings, an in-depth discussion of how these variables are related to the effectiveness of SA was provided, and recommendations for L2 learners and SA researchers involved in SA programmes were proposed.

Effects of different culture media on growth, composition, quality and palatability of the green algae Ulva sp. cultivated in cylindrical photobioreactors

Ulva spp. are valuable seaweeds with recognized commercial applications, including food, feed, and ecosystem services. Ensuring a sustainable and consistent supply of biomass with desirable profiles aligned with intended uses is fundamental for the successful applications of this seaweed. In this study, the growth rate, morphology, physiology, and composition of Ulva sp. produced by propagation in indoor cylindrical photobioreactors using four different culture media (lagoon water - LW, lagoon water enriched with Guillard medium (LF), with sea urchin wastewater - LU, and cow digestate - LD) was assessed; moreover, the nutrient uptake potential of the species was evaluated. The palatability and attractivity of the produced biomass towards the sea urchin Paracentrotus lividus were investigated. It was found that the media influenced all the parameters examined, the LF biomass weight was double compared to the other treatments and showed a slightly higher absorbance. Colorimetric analyses reported a significant darker color in Ulva sp. grown under enriched media. Ulva sp. showed higher nutrient removal potential in LF. The lipid content did not vary (2–3 % dry weight, DW), while the protein content ranged from 21 % in LF to 6–9 % in the other treatments. Carbohydrates and fiber content were significantly lower in LF (16 % and 30 %) compared to the other treatments, 27–34 %, and 41–48 %, respectively. Pigment content significantly varied, being higher in biomass grown in LF and LU. Sea urchins showed preferences for biomass grown under LU, followed by LD. This study shows how different nutrient sources affect the biochemical composition, growth, quality, and palatability of Ulva sp.. When cultivated under the synthetic enriched media (LF) the species exhibits characteristics better suitable for human consumption, although requiring a higher economic investment for production, while biomass derived from wastewater nutrients (LD, LU) confirms potential applications of the seaweed as valuable feed and for bioremediation services.