AbstractNarrow row spacing (<76 cm) could improve crop competitiveness, suppress weeds and might provide yield advantage. Many studies have been conducted to evaluate the impact of narrow row spacing; however, no quantitative synthesis of these studies exists. The objectives of this meta-analysis were to (1) quantify the overall effect of narrow row spacing (<76 cm) on weed density, biomass, control, weed seed production, and yield in corn (Zea mays L.) and soybean [Glycine max (L.) Merr.] compared with 76-cm row spacing, and (2) assess the influence of agronomic management decisions (tillage type, weed management, herbicide application frequency and time) on effect of narrow row spacing on weed suppression and corn and soybean yield. We compiled 1,904 pair-wise observations from 35 studies conducted in 12 states in the United States during 1961 to 2018. Averaged across individual observations, narrow row spacing suppressed weed density by 34%, weed biomass by 55%, and weed seed production by 45%, while it improved weed control by 32% and crop yield by 11% compared with 76-cm row spacing. Narrow row spacing in soybean suppressed weed density by 42%, weed biomass by 71%, and increased crop yield by 12% compared with 76-cm row spacing. Although narrow row spacing had a nonsignificant effect on response variables in corn, the number of studies (n = 1 to 6) and observations (n = 1 to 59) addressing each response variable were limited. Tillage type (conventional and reduced) did not influence the response of weed density, control, and seed production in narrow row spacing; however, weed biomass and weed seed production were more greatly reduced with the sequential application of herbicides compared with a single application. Thus, narrow row spacing in soybean can be integrated with other options for management of herbicide-resistant weeds.