As an effective technique for combating multipath fading and for high-bit-rate transmission over wireless channels, orthogonal frequency division multiplexing (OFDM) is extensively used in high-rate wireless communication systems, such as, the wireless local area network (WLAN) and the digital television terrestrial broadcasting (DTTB) systems, to support high performance bandwidth-efficient multimedia services. Multiple antennas and transmit or receive diversity, multiple-input multiple-output orthogonal frequency division multiplexing (MIMO-OFDM), can be used to improve error performance and capacity of wireless systems. In this paper, we consider the effects of carrier frequency offset and channel estimation errors on the performance of MIMO-OFDM systems in spatially correlated channels. Theoretical calculations and computer simulations are done to analyze the performance degradation of MIMO-OFDM systems in spatially correlated channels due to carrier frequency offset and channel estimation errors, and the theoretical and simulated results match well.