Background: The high Child Sexual Abuse (CSA) case in the Bengkulu City need anticipation intensive action. Children need to are provided with knowledge about the program underware rules that is useful as for Personal Safety Skill to protect themselves from risk of child sexual abuse. Aim: the purpose of this study is to compare ladder snake and busy book Andara in increasing knowledge of personal safety skills (PSS) against child sexual abuse for preschool. Methods: A quasi-experimental with a pretest-posttest control group design was used in this study. One hundred and seven pre-school were divided into two groups, ladder snake Andara group, and the busy book group. Samples were taken using a simple random sampling technique. Data were analyzed using Wilcoxon and Mann Whitney with SPSS software version 22.0. Result: There was a significant difference in knowledge of PSS between the two groups before and after treatment (p=0.000), and there was a significant difference knowledge of PSS in between the ladder snake and busy book Andara (p=0.002), with a higher mean rank ladder snake of 62,95. Conclusion: This study demonstrated that there was a significant difference in knowledge of PSS between two groups, and the ladder snake Andara showed better results in increasing knowledge of PSS among preschool compared to the busy book Andara. Recommendation: Development of interactive educational game tools with peers or parents is very important to improve children's knowledge of personal safety skills.