Nowadays, the industrial Internet of things (IIoT) and smart factories are relying on intelligence and big data analytics for large-scale decision making. Yet, this method is facing critical challenges regarding computation and data processing due to the complexity and heterogeneous nature of big data. Smart factory systems rely primarily on the analysis results to optimize production, predict future market directions, prevent and manage risks, and so on. However, deploying the existing classical solutions such as machine learning, cloud, and AI is not effective anymore. Smart factory systems and industries need novel solutions to sustain their development. On the other hand, with the fast development of quantum information systems (QISs), multiple sectors are studying the opportunities and challenges of implementing quantum-based solutions for a more efficient and exponentially faster processing time. To this end, in this paper, we discuss the implementation of quantum solutions for reliable and sustainable IIoT-based smart factory development. We depict various applications where quantum algorithms could improve the scalability and productivity of IIoT systems. Moreover, we design a universal system model where smart factories would not need to acquire quantum computers to run quantum algorithms based on their needs; instead, they can use quantum cloud servers and quantum terminals implemented at the edge layer to help them run the desired quantum algorithms without the need of an expert. To prove the feasibility of our model, we implement two real-world case studies and evaluate their performance. The analysis shows the benefits of quantum solutions in different sectors of smart factories.