The presented scientific article reveals the role of studying the comprehensive fea-tures of ensuring the economic security of business structures, taking into ac-count modern stressful situations. The examples of the impact of international processes on the economic security of companies are presented. Groups of risks have been identified for tobacco industry enterprises (legislative, social, econom-ic, technological and environmental), which can lead to stressful events that lead to an imbalance in their economic security system. The author's interpretation of the term "stressful event in business" is presented and the author's approach to the formation of a register of stressful situations in the system of economic securi-ty of tobacco industry enterprises is revealed. Special attention is paid to the main stages of the author's method of analyzing the multidimensional impact of stressful situations on the level of economic safety of a tobacco industry enter-prise, based on a point-based assessment of the desired parameters. The ad-vantage of the proposed toolkit is the ability to demonstrate the calculated values obtained in the matrix of stressful events, which will allow them to be divided in-to appropriate groups for subsequent analysis, application of mechanisms and methods of regulatory action