In populated downtown areas, a floor system with secured environmental performance is needed to reduce greenhouse gases (GHGs) and global warming problems related to buildings. This study aims to assess environmental impacts on a novel double-beam floor system subjected to high gravity loads. Life cycle assessment (LCA) was conducted to investigate the environmental impacts on the reduction in construction materials by calculating global warming potential (GWP) in the structural design phase. For different structural systems, the environmental performance was compared based on the GWP, and the contributions of structural elements to the GWP in each structural system were analyzed. The rotational constraints induced by the beam-end concrete panel can significantly reduce the GWP of the double-beam floor system by up to 13.8% compared to the conventional beam-girder system. Thus, the double-beam floor system reinforced with the concrete panel can be a candidate for eco-friendly structural systems in underground structures requiring high gravity loads. This result provides valuable findings that the structural effect on the rotational constraint of the concrete panel was quantitatively evaluated by converting it into an environmental impact.