Currently, import substitution, the presence of domestic quality products on the market, including alcoholic beverages, is an urgent direction in the food industry The technical grape variety "Isabella" is one of the most widespread in the Central Black Earth Region (CBER). The purpose of the work is to popularize the culture of wine consumption and saturate the food market of the CBER with high-quality wine materials and finished products. Objects of research were: five samples of the technical grape variety "Isabella" grown in different territories of the Voronezh, Belgorod, Lipetsk regions of the CBER: five samples of wine prepared from the above raw materials by the «red» method. When collecting grape raw materials, they were guided by the conditions of sugar content and acidity. The processing of grapes, the production of wine materials and finished wine was carried out according to the technological scheme for red table wine. As a result, the possibility of using the technical grape variety "Isabella" grown in the CBER is shown. The conditions of all five samples of grapes corresponded to the standards adopted in the wine production. According to the basic physico-chemical parameters, the obtained wine samples corresponded to the standards adopted for ordinary red semi-sweet wines. The evaluation of wine samples according to the indicator "Quantitative determination of trans-resveratrol" revealed a sample containing trans-resveratrol - a sample of wine № 4 obtained from grapes of the variety "Isabella" growing in the Lipetsk region, the city of Gryazi, Gryazinsky district. The content of trans-resveratrol in it was 0.143 mg/dm3. Resveratrol, having antioxidant activity, is of the greatest interest among biomolecules with nutraceutical properties in red wine. The separation and identification of trans-resveratrol was carried out using high-performance liquid chromatography (HPLC) coupled with a detector on a diode matrix (DAD-3000 model, Thermo Scientific). The calibration curve was constructed using a standard sample at increasing concentrations. Further development of research are: to develop the technology of terroir wine, which differs from other wines produced in other geographical latitudes with appearance, taste, aroma, which will be formed due to the influence of external factors.
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