The term "cupping therapy" refers to treatments that involve applying sucking cups to specific skin regions for therapeutic reasons. Cupping therapy is a straightforward, risk-free, comfortable, efficient, cost-effective, and time-saving procedure. Traditional wet cupping therapy is a two-step process that involves cupping first, then superficially scarifying the skin (also known as the double S technique). Traditional wet cupping therapy was found to be successful in treating carpal tunnel syndrome in a German study. Al-hijamah is a three-step method that involves wet cupping therapy in prophetic medicine (suction, scarification, and suction technique, ie, triple S technique). According to the evidence-based Taibah mechanism, al-hijamah is a successful excretory therapy that purges the blood and interstitial spaces of harmful pathogenic chemicals. we firmly advocated Al-hijamah in our earlier articles for normal medical practice in hospitals. Al-hijamah was strongly advised for the treatment of thalassemia. In healthy people, al-hijamah dramatically reduced serum ferritin levels. Al-hijamah is an excretory procedure that considerably purges blood of harmful chemicals. Thalassemia may be a good candidate for treatment with Al-hijamah to remove extra iron and ferritin from thalassemic blood (via percutaneous iron excretion), as we mentioned in earlier papers. Al-hijamah is a brand-new percutaneous iron excretion therapy (PIET), which we will explore in this article. Interestingly, despite their distinct etiologies and pathophysiology, autoimmune disorders and migraine headaches responded favorably to al-hijamah treatment.