Early Migration Research Articles

Early Migration Period Glassware in Chernyakhiv Culture. Networks of Distribution (Based on Glass Finds from Viitenky and Velyka Buhaivka Burial Grounds)

Early Migration Period Glassware in Chernyakhiv Culture. Networks of Distribution (Based on Glass Finds from Viitenky and Velyka Buhaivka Burial Grounds)

Migration patterns of acetabular cups: a systematic review and meta-analysis of RSA studies.

We conducted a systematic review and meta-analysis of RSA studies to investigate the early and long-term migration patterns of acetabular cups and the influence of implant factors on cup migration over time. We performed a systematic search of PubMed, Embase, and Scopus databases to identify all RSA studies of cup migration following primary total hip replacement (THR). Proximal migration at 3 and 6 months, 1, 2, 5, and 10 years were considered for analysis. Implant factors investigated included fixation type, head size, bearing surface, uncemented coating design, and the decade of RSA introduction. 47 studies reported the proximal migration of 83 cohorts (2,328 cups). Besides 1 threaded cup design, no implant factor investigated was found to significantly influence proximal migration. The mean pooled 2-year proximal migration of cemented cups (0.14 mm, 95% confidence interval [CI] 0.08-0.20) was not significantly different from uncemented cups (0.12 mm, CI 0.04-0.19). The mean pooled proximal migration at 6 months was 0.11 mm (CI 0.06-0.16) and there was no significant increase between 6 months and 2 years (0.015 mm, CI 0.000-0.030). 27 of 75 cohorts (36%) reported mean proximal migration greater than 0.2 mm at 2 years, which has previously been identified as a predictor of implants at risk of long-term loosening. Our meta-analysis demonstrated that the majority of cup migration occurs within the first 6 months. With one exception, no implant factors influenced the 2-year proximal migration of acetabular cups. 36% of studies with 2-year migration were considered at risk of long-term loosening. Further investigation and comparison against long-term survivorship data would validate 6-month and/or 1-year proximal migration measurements as an earlier predictor of long-term loosening than the current 2-year threshold.

Negotiating Values: Diyanet and the Syrian Refugee Crisis

If during the early Republican era migration was a controlled process serving nation-building, the on-going Syrian refugee crisis has reasserted, and, in the meantime, challenged Turkish national identity. This paper analyzes Diyanet’s religious narratives regarding the Syrian refugee crisis, its role in legitimizing the government’s refugee policy and the arising tensions between humanistic Islamic values and nationalism faced by the institution. Methodologically, I primarily relied on the content analysis of the Friday sermons released by Diyanet between 2011 and 2018.

Genetic variation associated with adult migration timing in lineages of Steelhead and Chinook Salmon in the Columbia River.

With the discovery of a major effect region (GREB1L, ROCK1) for adult migration timing in genomes of both Chinook Salmon and Steelhead, several subsequent studies have investigated the effect size and distribution of early and late migration alleles among populations in the Columbia River. Here, we synthesize the results of these studies for the major lineages of Chinook Salmon and Steelhead that include highly distinct groups in the interior Columbia River that exhibit atypical life histories from most coastal lineage populations of these two species. Whole-genome studies with high marker density have provided extensive insight into SNPs most associated with adult migration timing, and suites of markers for each species have been genotyped in large numbers of individuals to further validate phenotypic effects. For Steelhead, the largest phenotypic effect sizes have been observed in the coastal lineage (36% of variation for passage timing at Bonneville Dam; 43% of variation for tributary arrival timing) compared to the inland lineage (7.5% of variation for passage timing at Bonneville Dam; 8.4% of variation for tributary arrival timing) that overwinter in freshwater prior to spawning. For Chinook Salmon, large effect sizes have been observed in all three lineages for multiple adult migration phenotypes (Coastal lineage: percentage of variation of 27.9% for passage timing at Bonneville Dam, 28.7% for arrival timing for spawning; Interior ocean type: percentage of variation of 47.6% for passage timing at Bonneville Dam, 39.6% for tributary arrival timing, 77.9% for arrival timing for spawning; Interior stream type: percentage of variation of 35.3% for passage at Bonneville Dam, 9.8% for tributary arrival timing, 4.7% for arrival timing for spawning). Together, these results have extended our understanding of genetic variation associated with life history diversity in distinct populations of the Columbia River, however, much research remains necessary to determine the causal mechanism for this major effect region on migration timing in these species.

The ontogeny of lymphoid organs and IgM+ B-cells in ballan wrasse (Labrus bergylta) reveals a potential site for extrarenal B-cell lymphopoiesis: The pancreas

Vaccination of farmed fish is the most effective prophylactic measure against contagious diseases but requires specific knowledge on when the adaptive immune system is fully developed. The present work describes kidney and spleen morphogenesis as well as B-cell development in the ballan wrasse (Labrus bergylta). The kidney was present at hatching (0 days pot hatching, dph) but was not lymphoid before larvae was 50–60 dph (stage 5), containing abundant Igμ+ cells. The spleen anlage was first observed in larvae at 20–30 dph and was later populated with B-cells. Unexpectedly, we found strong RAG1 signal together with abundant Igμ+ and IgM + cells in the exocrine pancreas of larvae from when the kidney was lymphoid and onwards, suggesting that B-cell lymphopoiesis occurs not only in the head kidney (HK) but also in pancreatic tissue. In this agastric fish, the pancreas is diffused along the intestine and the early presence of IgM+ B-cells in pancreatic tissue might have a role in maintain immune homeostasis in the peritoneal cavity, making a substantial contribution to early protection. IgM-secreting cells in HK indicate the presence of systemic IgM at stage 5, before the first IgM+ cells were identified in mucosal sites. This work together with our previous study on T-cell development in this species indicates that although T- and B-cells start to develop around the same time, B-cells migrate to mucosal tissues ahead of T-cells. This early migration likely involves the production of natural antibodies, contributing significantly to early protection. Moreover, a diet composed of barnacle nauplii did not result in an earlier onset of B-cell lymphopoiesis, as seen in the previous study analysing T-cell development. Nevertheless, components for adaptive immunity indicating putative immunocompetence is likely achieved in early juveniles (>100 dph). Additionally, maternal transfer of IgM to the offspring is also described. These findings provide important insights into the development of the immune system in ballan wrasse and lay the foundation for optimizing prophylactic strategies in the future. Furthermore, this work adds valuable information to broaden the knowledge on the immune system in lower vertebrates.

The Caucasus and the Middle East in the early Holocene (According to recent archaeological research)

The article provides a comprehensive account of two significant prehistoric archaeological sites located in Adjara - Kobuleti village and Khutsubani, including their history, modern investigations, and findings. The authors highlight that bone remains were not uncovered during the excavation of Stone Age archaeological sites due to the soil'speculiarities. These remains could have shed light on the hunting environment of that era. Stone artifacts provide insight into the lives of ancient hunter-gatherers in our regionThus, a thorough examination of the stone industry is very important. According to this analysis the authors, a fascinating conclusion is drawn regarding the origins of the Western Transcaucasia stone industry. During the early Holocene era, a new method of stone processing and various types of tools emerged within the aforementioned region. This innovative approach was originally developed in the territory of Iran and Iraq. It's a Mlefaatien culture, which comprises of many significant sites. After conducting a techno-typological analysis of the stone complex, it is believed that hand pressure techniques, backed microblades, Kashkashok side-blow blade-flakes, grooved tools etc. emerged in Western Georgia result of the great migration process from Middle East in the beginning of the 10th millennia BC. This view is supported by the complete range of precise dates, which accurately reflect the migrations ways and times of the early migrants. Additional inquiries in this field, conducted in the future, will undoubtedly uncover even more fascinating insights.

Comparison between downdip and updip groundwater flow on early CO2 migration in dipping storage aquifers

The impact of the aquifer dip angle and groundwater flow have been investigated in the field of carbon dioxide (CO2) storage efficiency and security. However, no consideration has been given to the significance of the direction of groundwater flow in aquifers on the CO2 plume migration and the storage performance. In this study, we analyse the effect of the direction of groundwater flow on CO2 plume migration in the subsurface, implementing a numerical modelling approach. We compare the early plume migration in storage aquifers of various dip angles when the groundwater flows downdip with when it flows updip. We estimate the injected plume size, and the instantaneous velocity of the leading tip of the plume. When the groundwater flows downdip, against the direction of CO2 plume migration, the plume becomes more stretched, its greater extent and thus height causing it to accelerate during its updip migration due to the increase in buoyancy. By contrast, the plume decelerates over time when groundwater flows updip. This is because of a decrease in the size of the mobile CO2 plume due to enhanced residual and dissolution trapping at its trailing edge, reducing buoyancy, and hence decreasing the risk of CO2 leakage during its early migration.

Genetic Affinities and Adaptation of the South-West Coast Populations of India.

Evolutionary event has not only altered the genetic structure of human populations but also associated with social and cultural transformation. South Asian populations were the result of migration and admixture of genetically and culturally diverse groups. Most of the genetic studies pointed to large-scale admixture events between Ancestral North Indian (ANI) and Ancestral South Indian (ASI) groups, also additional layers of recent admixture. In the present study, we have analyzed 213 individuals inhabited in South-west coast India with traditional warriors and feudal lord status and historically associated with migratory events from North/North West India and possible admixture with West Eurasian populations, whose genetic links are still missing. Analysis of autosomal Single Nucleotide Polymorphism (SNP) markers suggests that these groups possibly derived their ancestry from some groups of North West India having additional Middle Eastern genetic components. Higher distribution of West Eurasian mitochondrial haplogroups also points to female-mediated admixture. Estimation of Effective Migration Surface (EEMS) analysis indicates Central India and Godavari basin as a crucial transition zone for population migration from North and North West India to South-west coastal India. Selection screen using 3 distinct outlier-based approaches revealed genetic signatures related to Immunity and protection from Viral infections. Thus, our study suggests that the South-west coastal groups with traditional warriors and feudal lords' status are of a distinct lineage compared to Dravidian and Gangetic plain Indo-Europeans and are remnants of very early migrations from North West India following the Godavari basin to Karnataka and Kerala.

High glucose impairs human periodontal ligament cells migration through lowered microRNAs 221 and 222.

To investigate the effects of miR-221 and miR-222 and high glucose on human periodontal ligament (PL) cells morphology, cytoskeleton, adhesion, and migration. Chronic hyperglycemia is common in uncontrolled diabetes mellitus (DM) and plays a central role in long-term DM complications, such as impaired periodontal healing. We have previously shown that high glucose increases apoptosis of human PL cells by inhibiting miR-221 and miR-222 and consequently augmenting their target caspase-3. However, other effects of miR-221/222 downregulation on PL cells are still unknown. Cells from young humans' premolar teeth were cultured for 7 days under 5 or 30 mM glucose. Directional and spontaneous migration on fibronectin were studied using transwell and time-lapse assays, respectively. F-actin staining was employed to study cell morphology and the actin cytoskeleton. MiR-221 and miR-222 were inhibited using antagomiRs, and their expressions were evaluated by real-time RT-PCR. High glucose inhibited PL cells early adhesion, spreading, and migration on fibronectin. Cells exposed to high glucose showed reduced polarization, velocity, and directionality. They formed several simultaneous unstable and short-lived protrusions, suggesting impairment of adhesion maturation. MiR-221 and miR-222 inhibition also reduced migration, decreasing cell directionality but not significantly cell velocity. After miR-221 and miR-222 downregulation cells showed morphological resemblance with cells exposed to high glucose. High glucose impairs human PL cells migration potentially through a mechanism involving reduction of microRNA-221 and microRNA-222 expression. These effects may contribute to the impairment of periodontal healing, especially after surgery and during guided regeneration therapies.

High-resolution seismicity imaging and early aftershock migration of the 2023 Kahramanmaraş (SE Türkiye) MW7.9 & 7.8 earthquake doublet

We build a high-resolution early aftershock catalog for the 2023 SE Türkiye seismic sequence with PALM, a seamless workflow that sequentially performs phase picking, association, location, and matched filter for continuous data. The catalog contains 29,519 well-located events in the two mainshocks rupture region during 2023-02-01–2023-02-28, which significantly improves the detection completeness and relocation precision compared to the public routine catalog. Employing the new PALM catalog, we analyze the structure of the seismogenic fault system. We find that the Eastern Anatolian Fault (EAF) that generated the first MW7.9 mainshock is overall near-vertical, whereas complexities are revealed in a small-scale, such as subparallel subfaults, unmapped branches, and stepovers. The seismicity on EAF is shallow (<15 km) and concentrated in depth distribution, indicating a clear lock-creep transition. In contrast, the Sürgü Fault (SF) that is responsible for the second MW7.8 mainshock is shovel-shaped for the nucleation segment and has overall low dip angles (∼40°–80°). Aftershocks on the SF distribute in a broad range of depth, extending down to ∼35 km. We also analyze the temporal behavior of seismicity, discovering no immediate foreshocks within ∼5 days preceding the first mainshock, and no seismic activity on the SF before the second mainshock.

Partitioning survival during early marine migration of wild and hatchery-reared Atlantic salmon (Salmo salar L.) smolts using acoustic telemetry

The marine migration of Atlantic salmon (Salmo salar) has been prioritised for research internationally as populations of S. salar have declined significantly throughout the species’ range. The main objectives of this study were to use acoustic telemetry to partition survival during the early migration phase, investigate potential causes of mortality and establish diurnal and tidal influences on movements. In 2017 and 2018 wild (n = 49) and hatchery (n = 81) S. salar smolts were tagged with acoustic transmitters. Migration was monitored through a brackish tidal lake, which discharges through a short estuary into northeast Clew Bay in Ireland situated in the northeast Atlantic. Partitioned survival through each area was similar for both wild and hatchery smolts and both groups followed the same migration routes, travelling along the main current out of Clew Bay. Total survival was high within the brackish lake (wild = 98% ± 1.21 and hatchery = 100%) and estuary (wild = 98% ± 1.01 and hatchery = 89% ± 9.28) compared to the marine environment (wild = 67% ± 4.39 and hatchery = 66% ± 7.91). Leaving the brackish lake during an ebb tide and entering the marine environment during daylight increased the probability of survival through the early marine period. The majority of smolts transited through the study area during ebb tides. Migration of hatchery smolts occurred mainly during hours of daylight while wild smolt migration showed no diel patterns. High mortality rates during the initial stages of the marine migration have consequences for the persistence of salmon populations and should be addressed through regionally tailored management measures and conservation efforts aimed at increasing the resilience of salmon stocks.

Spring temperature predicts upstream migration timing of invasive Sacramento pikeminnow within its introduced range

Rapid climate change and invasive species introductions threaten ecological communities across the globe. Freshwaters are particularly vulnerable and impacted, especially when these stresses coincide. We document the migration of an invasive piscine predator, the Sacramento pikeminnow (Ptychocheilus grandis), within its introduced range, the South Fork Eel River, California, USA. Snorkel surveys and temperature monitoring in 2015–2019 showed that pikeminnow migrate upstream during spring and early summer, with earlier migration in warmer years. We developed a statistical temperature model to forecast the timing and extent of upstream migration by pikeminnow under varying combinations of discharge and air temperature. Modeled river temperature increased with air temperature and downstream and decreased with discharge. In years with low discharge and high air temperature, we predict pikeminnow will move upstream earlier, increasing spatial and temporal overlap in their summer range with native fishes. Managing conditions that reduce pikeminnow co-occurrence with native fishes (i.e., decreasing river temperature) could increase amount and duration of predator-free habitat for native fishes. We predict invasive pikeminnow will have larger impacts on invaded riverine communities with global warming and increasing drought severity. Knowledge of life history and phenology, for pikeminnow and other organisms, can guide effective management as conditions change and help to limit adverse impacts of introduced organisms on native species.

Numerical analysis on the direction of groundwater flux effects on the early post-injection migration of a CO2 plume

Several parameters have been analysed in the field of carbon dioxide (CO2) subsurface storage efficiency and security, including the aquifer dip and background water flow, for proper selection of CO2 storage aquifer sites. However, less importance has been assigned to the impact of the direction of groundwater flow on the migration of the injected CO2 plume, and hence the aquifer storage performance. This study investigates, using a numerical modelling method, the effect of the direction and magnitude of groundwater flux on the CO2 plume displacement and trapping in dipping aquifers during the early stages of the post-injection migration. The groundwater flow is established using water injection and production wells at the extremities of the model, while the direction of flow is altered from downdip to updip by swapping the locations of these wells. The study estimates and compares the extent of the total injected plume and the mobile portion of the plume, in addition to the instantaneous velocity of the leading tip of the plume, when groundwater flows downdip and when it flows updip. Our results indicate that when the groundwater flows downdip, counter to the overall direction of the CO2 plume migration, the plume is more stretched in both the updip and downdip directions than when groundwater flows updip. The size of mobile CO2 plume enlarges to a greater extent with downdip groundwater flow, causing the advancing tip to accelerate during its updip migration due to increasing buoyancy, with the effect being more pronounced at lower flow velocities. This increases the risk of CO2 leakage during the early stages of the plume migration when groundwater flows downdip. On the other hand, updip groundwater flow reduces the risk of leakage by reducing the velocity and extent of the plume, and increasing the impact of trapping mechanisms. Thus, the direction of groundwater flow can control the migration velocity of the CO2 plume in dipping storage aquifers, not due primarily to any induced viscous force, but due to the impact of trapping on buoyancy. Therefore, choosing the appropriate injection location for CO2 relative to the direction of flux is important for storage efficiency.

Construction of multifunctional coating with cationic amino acid-coupled peptides for osseointegration of implants

Osseointegration is an important indicator of implant success. This process can be improved by coating modified bioactive molecules with multiple functions on the surface of implants. Herein, a simple multifunctional coating that could effectively improve osseointegration was prepared through layer-by-layer self-assembly of cationic amino acids and tannic acid (TA), a negatively charged molecule. Osteogenic growth peptide (OGP) and the arginine-glycine-aspartic acid (RGD) functional polypeptides were coupled with Lys6 (K6), the two polypeptides then self-assembled with TA layer by layer to form a composite film, (TA-OGP@RGD)n. The surface morphology and biomechanical properties of the coating were analyzed in gas and liquid phases, and the deposition process and kinetics of the two peptides onto TA were monitored using a quartz crystal microbalance. In addition, the feeding consistency and adsorption ratios of the two peptides were explored by using fluorescence visualization and quantification. The (TA-OGP@RGD)n composite membrane mediated the early migration and adhesion of cells and significantly promoted osteogenic differentiation and mineralization of the extracellular matrix in vitro. Additionally, the bifunctional peptide exhibited excellent osteogenesis and osseointegration owing to the synergistic effect of the OGP and RGD peptides in vivo. Simultaneously, the (TA-OGP@RGD)n membrane regulated the balance of reactive oxygen species in the cell growth environment, thereby influencing the complex biological process of osseointegration. Thus, the results of this study provide a novel perspective for constructing multifunctional coatings for implants and has considerable application potential in orthopedics and dentistry.

Evidence of early human migration and tool-making challenges assumptions about evolution

Evidence of early human migration and tool-making challenges assumptions about evolution

Cave funeral practices during the Roman and Migration Periods in the Cracow Upland, southern Poland

Although caves have been used for funerary purposes almost since the dawn of time, there is very little evidence of such use in Central European Barbaricum. This paper presents newly obtained results from the Cracow Upland (southern Poland) concerning multiple skeletal remains that apparently share a similar third–fifth centuries AD chronology, corresponding to the Late Roman and Early Migration Periods. Multiple analyses have been performed to supplement archaeological data, including radiocarbon dating, osteoarchaeological analysis, ancient DNA research and isotopic analysis. The complex picture points towards unusual burial practices, which generally spanned from the third to the fifth centuries AD and involved a broad demographic, with no indication of selection based on an individual's biological profile. Isotopic analysis has also indicated the individuals’ heterogeneity with regard to diet and local versus nonlocal origin. The results point towards the previously unrecognized unique role of caves in the Przeworsk culture, then present in southern Poland.

Serengeti–Masai Mara ecosystem dynamics inferred from rainfall extremes

The Serengeti–Masai Mara Ecosystem (SMME) is an iconic ecological and biodiversity resource in East Africa with a spectacular great animal migration feature. Environmental shocks like droughts, floods, and land degradation threaten the SMME’s ecological functioning. However, the spatiotemporal ecosystem dynamics during climate extremes are inadequately examined. Here we quantified water availability and vegetation changes during extreme wet (EWE) and dry (EDE) events over the SMME for wet and dry seasons in 1982–2020. We derived extreme events from seasonal mean precipitation anomaly exceeding standard deviation and applied composite and correlation techniques to assess their dynamics with animal populations and migration prospects. Wet season EWE increases vegetative and moist conditions over southern SMME, suggesting elongating migrants’ occupancy compared to normal periods and delayed northward migration. Wet season EDE significantly suppresses these features, heightening ecosystem competition and survival threats, proposing an earlier northward migration. Dry season EWE increases vegetation and water availability over northern SMME, prompting the late southward migration. Dry season EDE significantly reduces vegetation and water availability over northern SMME, suggesting an early southward migration towards regions with more vegetation and increased water availability. The SMME also experiences multiple EDE occurring in consecutive seasons, prolonging dry conditions that aggregate wildlife survival threats. Notably, two EDE prevailed consecutively from the 1993 dry season to the 1994 wet season, coupled with a population decline of wildebeest (1.2–0.9 million), buffalo (40–20 thousand), and lion (1.3–0.9 thousand). We also note a reversal from more EDE to EWE during the study period. Prevalent EWE can lessen wet and vegetative conditions distribution gradient, which is imperative for the functioning of the SMME migratory ecosystem. Our study unveiled hotspot areas of extremes-driven ecosystem changes for the sustainable SMME migratory functioning essential for framing meaningful conservation management policies under climate change.

Embryology, anatomy and physiology of the liver: Review

The liver, located within the peritoneal cavity, is in the right upper quadrant of the abdomen. Additionally, it should be noted that the liver holds the distinction of being the largest gland within the human body, as well as the most extensive visceral tissue situated within the abdominal cavity. One of the factors contributing to the early migration of the developing intestines to an extracoelomic location during fetal development is their relatively bigger size in children, weighing between 1400 and 1800 g in adults. It contributes to the development of a distended abdomen in pediatric populations. The liver is situated in the right upper quadrant of the abdomen and spans across the midline to the left upper quadrant. The heart remains susceptible to regular injuries despite the protective presence of ribs and cartilage. The liver, functioning as an accessory organ in digestion, undertakes several metabolic processes, including drug metabolism, bile production, and bilirubin synthesis, alongside numerous other functions. For a considerable period, medical professionals and anatomists have encountered challenges in comprehending the complex functions of the liver. Significant advancements in the comprehension of liver anatomy have contributed significantly to the notable progress observed in various surgical and interventional radiologic procedures involving hepatic artery infusion pumps, liver ablation, transplantation, transarterial chemoembolization, selective internal radiation therapy, and portal vein embolization. The existence of hepatic structure is crucial for developing and implementing gradual therapies. This page aims to provide an academic overview of the embryology, anatomy, and function of the liver.

Using extended growth of cattle embryos in culture to gain insights into bovine developmental events on embryonic days 8 to 10

We have previously described an extended embryo culture system, based on uterine composition, growth factors and the cell culture additive B27, for growing cattle embryos in vitro beyond embryonic day 7. Here, extended in vitro embryos are compared to embryos developed in the uterus and are used to establish a developmental staging framework useful for understanding developmental events occurring until Day 10. Immunofluorescence or mRNA expression of the ICM/epiblast markers OCT4, SOX2 and NANOG, hypoblast markers GATA6, SOX17 and GATA4 and trophoblast genes CDX2, GATA3, ASCL2 and IFNT revealed the presence of four stages during this period that can be molecularly distinguished. These are expanded blastocyst, hatched blastocyst, hypoblast layering and early hypoblast migration. Interestingly NANOG and SOX17 show reciprocal expression at the expanded blastocyst stage, well before SOX2 and GATA6 expression refines to a similar so-called “salt and pepper” mutually exclusive expression in the ICM at the hatched blastocyst stage. GATA4 expression is only seen from stages when the hypoblast starts migrating around the blastocyst cavity. Intriguingly, trophoblast still expresses GATA6 and OCT4 in all cells during the expanded blastocyst phase, while SOX2 and SOX17 are seen in only some trophoblast cells. By the hypoblast-epiblast layering stage no trophoblast expression remains except for that of OCT4 protein, which starts waning in trophoblast once the hypoblast begins migrating. Lastly, it is shown that cultured embryos exhibit increased expression of the stress marker TP53 in the epiblast and hypoblast at late stages in comparison to embryos produced in the uterine environment.

Incidence and outcomes of intraoperative periprosthetic acetabular fractures during cementless total hip arthroplasty: a prospective three-dimensional computer tomography-based study.

Unlike periprosthetic femoral fractures, periprosthetic acetabular fractures during total hip arthroplasty (THA) have not been evaluated in detail. We prospectively evaluated the incidence, patterns, risk factors, and clinical outcomes of intraoperative periprosthetic acetabular fractures using pre- and postoperative computer tomography (CT). In this prospective single-centre study, we evaluated 234 consecutive patients (250 hips) who underwent THA and three-dimensional CT before and after the surgery. We assessed the incidence, pattern of fractures, outcomes for each fracture pattern, reoperation and revision rates, Harris hip score, and visual analog scale (VAS) for pain. Multivariate regression models were used to identify risk factors for periprosthetic acetabular fractures. In total, 43 periprosthetic acetabular fractures (17.2%) were identified via CT. Fractures occurred most frequently at the superolateral wall. Early cup migration occurred in three hips. None of the patients underwent revision surgery for acetabular loosening. Regression modeling showed that rheumatoid arthritis was a significant predictor of periprosthetic acetabular fractures. Periprosthetic acetabular fractures are not infrequent during cementless THA and are more common in patients with rheumatoid arthritis.