Marine fisheries are a critical component of the marine economy. Examining the changes in the economic resilience of marine fisheries allows for identifying potential development risks and supports informed decision-making to optimize growth patterns and mitigate risks. This study applied the CRITIC-based combined weights model to calculate China’s Marine Fisheries Economic Resilience (MFER). It investigated the temporal and spatial evolution of MFER and analyzed the influencing factors using the Geographical Detector and a Two-way fixed-effects model. Furthermore, the future development trends of MFER were predicted using the Markov chain. The results show that the overall MFER in China’s coastal provinces increased steadily from 2001 to 2020. Second, MFER exhibits a clear pattern, with low-value regions improving and high-value areas shifting toward medium- and low-value provinces. Fourth, the trajectory of the MFER center is moving from north to south, with high-value regions expanding in the same direction. Fourth, factors such as EDL, TEC, SPE, and SYS positively impact MFER, while OPE has a negative effect. Finally, the results of the Markov chain indicate that the current development state of MFER is relatively stable, with evidence of club convergence. However, the probability of maintaining the current development level is gradually decreasing. Based on these findings, provide suggestions for the preservation of marine economic security.