AbstractTo attain a thorough examination of the dynamic interaction mechanism between China's utilization of water resources and its economic and social development, this paper innovatively introduces a Western theoretical framework within an Eastern context. The aim is to quantify the process of decoupling and synergistic evolution from 2006 to 2020. Decoupling signifies achieving economic growth while reducing resource use or mitigating environmental impacts, whereas synergy denotes enhancing economic efficiency while contributing to environmental protection. This paper employs the Tapio elastic coefficient method to construct a decoupling model. A collaborative model, based on the entropy weight Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) and weighted average methods, also assesses the organization and coordination of subsystems within the complex water‐economic‐social system. The findings reveal a strong decoupling between China's water resource management and economic and social systems, as indicated by a consistently negative decoupling index. Similarly, the economic system exhibits a degree of inefficiency influenced by factors like economic cyclicality and resource allocation. In contrast, the social system experienced a decline, particularly during the pandemic (2019–2020), leading to a social instability. This study provides valuable policy formulation and sustainable development insights, contributing to a comprehensive understanding of the intricate dynamics between water utilization, economy, and society.