Peak Duration Research Articles

Contributions of anemia to exercise intolerance in heart failure with preserved ejection fraction-An exercise stress echocardiographic study.

Anemia is common in patients with heart failure with preserved ejection fraction (HFpEF) and is associated with exercise intolerance. However, there are limited data on how anemia contributes to reduced exercise capacity in patients with HFpEF. We aimed to characterize exercise capacity, cardiovascular and ventilatory reserve, and the oxygen (O2) pathway in anemic patients with HFpEF. A total of 238 patients with HFpEF and 248 dyspneic patients without HF underwent ergometry exercise stress echocardiography with simultaneous expired gas analysis. Patients with HFpEF were classified into two groups based on the presence of anemia (hemoglobin<13.0g/dL in men and<12.0g/dL in women). Anemic HFpEF patients (n=112) had worse nutritional status and renal function, lower iron levels, and greater left ventricular (LV) remodeling and plasma volume expansion than those without anemia (n=126). Exercise capacity, assessed by peak oxygen consumption, exercise intensity, and exercise duration, was lower in the anemic HFpEF group than in the other groups. Despite a similar cardiac output during exercise, anemic patients with HFpEF demonstrated limitations in arterial O2 delivery, lower arteriovenous O2 content difference, and ventilatory inefficiency (higher minute ventilation vs. carbon dioxide production slope) during peak exercise. Anemic HFpEF patients demonstrated unique pathophysiological features with greater LV remodeling and plasma volume expansion, limitations in arterial O2 delivery and peripheral O2 extraction, and ventilatory inefficiency, which may contribute to reduced exercise capacity. Further studies are needed to develop an optimal approach for treating anemia in patients with HFpEF.

Signatures of the Self-organized Criticality Phenomenon in Precursors of Gamma-Ray Bursts

Precursors provide important clues to the nature of gamma-ray burst (GRB) central engines and can be used to contain GRB physical processes. In this Letter, we study the self-organized criticality in precursors of long GRBs in the third Swift/Burst Alert Telescope catalog. We investigate the differential and cumulative size distributions of 100 precursors, including peak flux, duration, rise time, decay time, and quiescent time with the Markov Chain Monte Carlo technique. It is found that all of the distributions can be well described by power-law models and understood within the physical framework of a self-organized criticality system. In addition, we inspect the cumulative distribution functions of the size differences with a q-Gaussian function. The scale-invariance structures of precursors further strengthen our findings. Particularly, similar analyses are made in 127 main bursts. The results show that both precursors and main bursts can be attributed to a self-organized criticality system with the spatial dimension S = 3 and driven by a similar magnetically dominated process.

Experimental study of the effect of pump pulse duration on liquid crystal laser performance.

Much work has been done to understand the factors that impact photonic band-edge liquid crystal (LC) laser threshold and slope efficiency, two parameters often stated to quantify performance. Conventionally, LC lasers are optically pumped using Q-switched lasers with a fixed pulse duration, and thus the effect of pump pulse duration on LC laser performance has received little attention. While some studies have been published at different pump pulse durations, these use different laser sources and experimental conditions, making the data incomparable. By exploiting a recent breakthrough in laser diode pumping, our experimental results prove and quantify the detrimental effect of an increase in pump pulse duration on LC laser performance. We also show that the dependency of threshold on pump pulse duration depends on how threshold is defined, owing to an ambiguity in the definition of pulse energy in systems where peak power and pulse duration can be independently controlled. For improved comparison within the literature on LC laser device performance, we thus propose an alternative convention, whereby threshold is stated in units of peak power density.

Laser ignition and flame propagation of methanol-air mixture in a constant volume combustion chamber

ABSTRACT The combustion performance of laser-ignited methanol-air mixture in a constant volume combustion chamber was investigated using the Schlieren photography technique. The experimentation was conducted at 5, 7, 9, and 11 MPa fuel injection pressure and 363 K initial chamber temperature using a neodymium-doped yttrium aluminum garnet (Nd:YAG) laser of 1064 nm wavelength. The gasoline direct injection (GDI) system was used for injecting the fuel at different pressures inside the chamber. The laser beam is focused into the chamber using a 150 mm focal length lens, and laser energy of 200 mJ was used for all experimentation. The Schlieren system was used for capturing flame propagation of methanol-air mixture for different equivalence ratios. The pressure-time history for equivalence ratio (ϕ) of 0.8, 0.9, and 1.0 was plotted and analyzed at different chamber filling pressures. Flame propagation was found faster for ϕ of 1.0 due to higher laminar velocity than 0.8 and 0.9. Flame visualization showed that the flame attains the ellipsoid shape during the early stage of ignition. It generates two lobes in the vertical direction and then again expands in a horizontal direction toward the ignition source. For all equivalence ratios, the flame propagation toward the incoming laser source (X-) was observed faster compared to the flame propagation in the direction and perpendicular to the laser beam direction. For all equivalence ratios, higher laminar flame speed was observed at 5 MPa injection pressure; however, it decreases as the injection pressure increases. At ϕ of 1.0 and 11 MPa injection pressure, the maximum peak pressure of 0.67 MPa and combustion duration of 19.3 ms were noted. At 9 MPa injection pressure and ϕ of 1.0, the peak pressure and combustion duration was found as 0.61 MPa and 19.4 ms, respectively. At ϕ of 0.8, the peak pressure and combustion duration were observed 0.27 MPa with 34.6 ms duration and 0.47 MPa with 36.9 ms duration at 5 MPa and 11 MPa injection pressures, respectively.

Experimental study comparing two different phacoemulsification systems with IOP control during steady-state flow and occlusion break surge events.

To compare peak surge and surge duration time after occlusion break, incision leakage compensation, and passive vacuum for 2 phacoemulsification systems. Carl Zeiss Meditec AG, Oberkochen, Germany. Laboratory study. A spring-eye model was used to test Alcon Centurion Vision and Zeiss Quatera 700 systems. Peak surge and duration was measured after an occlusion break. Quatera tested in flow and vacuum priority modes. Vacuum limits ranged from 300 to 700 mm Hg with intraocular pressure (IOP) set at 30 mm Hg, 55 mm Hg, and 80 mm Hg. IOP vs incision leakage rates of 0 to 15 cc/min and passive vacuum were measured. At 30 mm Hg IOP set point and vacuum limits ranging 300 to 700 mm Hg, the surge duration time after occlusion break ranged 419 to 1740 milliseconds (ms) for Centurion, 284 to 408 ms for Quatera in the flow mode, and 282 to 354 ms for Quatera in the vacuum mode. At 55 mm Hg, values ranged 268 to 1590 ms for Centurion, 258 to 471 ms for Quatera in the flow mode, and 239 to 284 ms for Quatera in the vacuum mode. At 80 mm Hg, values were 243 to 1520 ms for Centurion, 238 to 314 ms for Quatera in the flow mode, and 221 to 279 ms in the vacuum mode. Centurion exhibited slightly less peak surge than the Quatera. At 55 mm Hg: incision leakage rates 0 to 15 cc/min, Quatera held the IOP within ±2 mm Hg of target; Centurion was unable to hold IOP target allowing a 11.7 mm Hg decrease with 32% higher passive vacuum. Quatera demonstrated slightly higher surge peak values and notably shorter surge duration times after occlusion break than Centurion. Quatera demonstrated better incision leakage compensation and lower passive vacuum than Centurion.

Effect of vaporizing cannabis rich in cannabidiol on cannabinoid levels in blood and on driving ability – a randomized clinical trial

The aim of this prospective, placebo-controlled, double-blind, randomized, cross-over study was to determine cannabinoid levels in blood and driving-related ability after single (S1) and repetitive (S2) vaporization of cannabis rich in cannabidiol (CBD) containing < 1% Δ9-etrahydrocannabinol (THC). Healthy adult volunteers (Nsingle = 27, Nrepetitive = 20) with experience in smoking vapor-inhaled two low-THC/CBD-rich cannabis products both with < 1% THC (product 1: 38 mg CBD, 1.8 mg THC; product 2: 39 mg CBD, 0.6 mg THC) and placebo. Main outcomes were THC- and CBD-levels in whole blood and overall assessment of driving-related ability by computerized tests. Among 74 participants included, 27 (mean age ± SD, 28.9 ± 12.5 years) completed S1, and 20 (25.2 ± 4.0) completed S2. Peak concentrations and duration of detectability depended on the THC-content of the product. After single consumption THC dropped below 1.5 µg/L after 1.5 h, but was detected in some participants up to 5 h. Pairwise comparison of driving-related ability revealed no significant differences between low-THC/CBD-rich products (P1, P2) and placebo. Detection of THC after consumption of low-THC/CBD-rich cannabis might have legal consequences for drivers. Regarding overall driving-related ability, no significant differences were observed between the interventional products. This trial was registered with the German Clinical Trials Register (DRKS00018836) on 25.10.2019 and with the Coordination Office for Human Research (kofam) which is operated by the Federal Office of Public Health (FOPH) (SNCTP000003294).

Utilisation of transitional clusters exhibited within soccer game play to inform training design

The aims of this study were to investigate the effect of 15min blocks on physical metrics during transitions, analyse frequency, type, duration, and recovery period between clusters of transitional activities (CTA) in elite football. During ten official matches 23 elite footballers were tracked using GPS devices. Metrics per minute (m·min-1) as well as absolute variables: total distance (TD), high-speed running distance (HSRD &gt; 19.8 km·h-1), sprint distance (SD &gt; 25.2 km·h-1), relative high-speed running distance (VelB4), relative sprint distance (VelB5), acceleration distance (AccB3 Dist, distance with variations in running speed &gt; 3 m·s-2), the number of high-intensity accelerations (HI Acc &gt; 3 m·s-2) and decelerations (HI Dec &gt; 3 m·s-2) were quantified. Significant effects of 15min blocks were found for TD (m) (p &lt; .001; ES = .078), TD (m·min-1) (p = .047; ES = .036), HSRD (m) (p = .033; ES = .039), VelB4 (m) (p &lt; .001; ES = .132), and HI Dec (n·min-1) (p = .002; ES = .059). Transitional activities recovery period was found to be 108.5 ± 26.2 s, CTA recovery period was 25.7 ± 3.6 s, while CTA peak duration reached 53.3 ± 18.2 s. This study indicates that physical metrics decrease in the last 15min blocks during transitions and high-pressure activities in games. In conclusion, repeated high intensity / high velocity activities frequently occur during contextualized peak intensity periods (transitions) in football, which should be reflected in modern training design.

Sensitivity investigation of 100-MeV proton irradiation to SiGe HBT single event effect

The single event effect (SEE) sensitivity of silicon–germanium heterojunction bipolar transistor (SiGe HBT) irradiated by 100-MeV proton is investigated. The simulation results indicate that the most sensitive position of the SiGe HBT device is the emitter center, where the protons pass through the larger collector-substrate (CS) junction. Furthermore, in this work the experimental studies are also carried out by using 100-MeV proton. In order to consider the influence of temperature on SEE, both simulation and experiment are conducted at a temperature of 93 K. At a cryogenic temperature, the carrier mobility increases, which leads to higher transient current peaks, but the duration of the current decreases significantly. Notably, at the same proton flux, there is only one single event transient (SET) that occurs at 93 K. Thus, the radiation hard ability of the device increases at cryogenic temperatures. The simulation results are found to be qualitatively consistent with the experimental results of 100-MeV protons. To further evaluate the tolerance of the device, the influence of proton on SiGe HBT after gamma-ray (60Coγ) irradiation is investigated. As a result, as the cumulative dose increases, the introduction of traps results in a significant reduction in both the peak value and duration of the transient currents.

Towards a high-resolution modelling scheme for local-scale urban flood risk assessment based on digital aerial photogrammetry

With the rapid development of cities and the impact of climate change, cities located near rivers are facing an increasingly serious flood threat. Urban flood risk prediction management is pressing. The peak discharge and duration are important factors in urban flood management as well as the important characteristics of flood hygrograph. Mostly, hydrological model is used to obtain the upstream flood hygrograph to drive inundation model. However, lack of information on reservoirs, barrage structures and land use make it difficult to construct high-precision hydrological models, especially in upstream cities where data is lacking. In this study, therefore, we propose an approach to urban flood management based on measured flood data from urban hydrological stations in close proximity to derive flood hydrography for different return periods, and establish a high-precision urban-scale river flood risk management method by combining with Unmanned Aerial Vehicle (UAV) survey data. This method can allow information on river construction and underlying surface change to be introduced into the flood hygrograph implicitly, thus avoiding the difficulty of establishing hydrological and hydrodynamic coupling of the whole basin. The applicability and accuracy of the methodology are explored in this article with reference to Chenxi City in the upper reaches of Yuanshui River. Comparison the flood process of the 10-year with the actual flood in 2016 indicates that the extent of inundation is strongly dependent on the instantaneous discharge, with the peak flow largely determining the maximum inundation extent and risk level. This illustrates the feasibility of risk assessment of urban flooding based on flood hygrograph with different period levels derived from measured flood processes at adjacent sites. Subsequently, the different return periods scenario is simulated and analyzed. This approach provides technical guidance for flood risk assessment in areas where data is lacking (e.g., upstream mountainous cities).

Altitude influence on the explosion shock wave pressure distribution

The explosion shock wave pressure distribution law is significantly affected by the altitude. It is very important to clarify the altitude impact on the explosion shock wave pressure propagation law for guiding the shock wave pressure test and accurately evaluating the ammunition damage power. The paper reviews the finite element numerical simulation and actual testing results of researchers at home and abroad regarding the propagation of explosive shock wave pressure through different air and water mediums, and clarifies the impact of altitude on characterization parameters of shock wave pressure such as peak pressure, impulse, and positive pressure duration. Based on the current research status both domestically and internationally, we have pointed out the main problems that still exist in the current research process and proposed research directions that need to be focused on in subsequent studies.

Aging Model for Analyzing Drug-Induced Proarrhythmia Risks Using Cardiomyocytes Differentiated from Progeria-Patient-Derived Induced Pluripotent Stem Cells.

Among various cardiac safety concerns, proarrhythmia risks, including QT prolongation leading to Torsade de Pointes, is one of major cause for drugs being withdrawn (~45% 1975-2007). Preclinical study requires the evaluation of proarrhythmia using in silico, in vitro, and/or animal models. Considering that the primary consumers of prescription drugs are elderly patients, applications of "aging-in-a-dish" models would be appropriate for screening proarrhythmia risks. However, acquiring such models, including cardiomyocytes (CMs) derived from induced pluripotent stem cells (iPSCs), presents extensive challenges. We proposed the hypothesis that CMs differentiated from iPSCs derived from Hutchinson-Gilford progeria syndrome (HGPS, progeria) patients, an ultra-rare premature aging syndrome, can mimic the phenotypes of aging CMs. Our objective, therefore, was to examine this hypothesis by analyzing the response of 11 reference compounds utilized by the Food and Drug Administration (FDA)'s Comprehensive in vitro Proarrhythmia Assay (CiPA) using progeria and control CMs. As a sensitive surrogate marker of modulating cardiac excitation-contraction coupling, we evaluated drug-induced changes in calcium transient (CaT). We observed that the 80% CaT peak duration in the progeria CMs (0.98 ± 0.04 s) was significantly longer than that of control CMs (0.70 ± 0.05 s). Furthermore, when the progeria CMs were subjected to four doses of 11 compounds from low-, intermediate-, and high-risk categories, they demonstrated greater arrhythmia susceptibility than control cells, as shown through six-parameter CaT profile analyses. We also employed the regression analysis established by CiPA to classify the 11 reference compounds and compared proarrhythmia susceptibilities between the progeria and control CMs. This analysis revealed a greater proarrhythmia susceptibility in the progeria CMs compared to the control CMs. Interestingly, in both CMs, the compounds categorized as low risk did not exceed the safety risk threshold of 0.8. In conclusion, our study demonstrates increased proarrhythmia sensitivity in progeria CMs when tested with reference compounds. Future studies are needed to analyze underlying mechanisms and further validate our findings using a larger array of reference compounds.

Surface Electromyographic Activity of the Masseter Muscle During Regular and Effortful Saliva Swallows: A Preliminary Study.

Biofeedback is a critical component in motor learning of new, complex behaviors such as modifications to swallowing. Surface electromyography (sEMG) is a commonly employed biofeedback tool in swallowing management to assess muscle activity patterns, determine amplitude and duration of swallowing, and train swallowing strategies such as the effortful swallow (EFS) maneuver. The EFS can potentially change multiple physiological components of the swallowing process such as pressure generation and movement of biomechanical structures. The purposes of this study were to determine whether the masseter muscle could differentiate a normal swallow (NS) from an EFS and whether there was a relationship between perceived muscle effort used to swallow and objective measures of muscle activity. Twenty healthy young adults participated in this study. Masseter sEMG peak amplitude and duration were measured across five regular saliva swallows and five effortful saliva swallows. Additionally, participants rated their perceived swallowing effort using a visual analog scale (VAS). Two swallowing conditions, NSs and EFSs were compared with hierarchical models, and repeated measures correlation was used to determine the relationships between the VAS and sEMG peak amplitude. Participants produced swallows with greater masseter sEMG peak amplitude and duration during the EFS. Moreover, a positive correlation was identified between perceived swallowing effort and masseter sEMG peak amplitude. These findings support the potential use of the masseter muscle to differentiate NSs from EFSs and implement the VAS during therapy for tracking patients' performance, particularly in settings with limited access to sEMG.

Numerical Simulation to Investigate Interactions of Generated Underwater Micro Shock Waves and Micro Bubbles by Focusing Femtosecond Pulse Laser

The purpose of this study is to elucidate the mechanism of propagation of the laser-induced micro shock waves under condition where the micro bubbles are generated. In this paper, effects of generated micro bubbles on propagation of the laser-induced micro shock waves were investigated by CFD (computational fluid dynamics). Firstly, the two models (1-D model and 1-D spherical symmetric model) were computed for comparison of the peak pressure variation of the shock waves with propagation. As for governing equations for the propagation of the shock waves, continuity equation, Euler’s momentum equation and Tait’s state equation are used. From the computation, it is confirmed that attenuation of pressure of the 1-D spherical symmetric model was earlier than the 1-D model. In addition, the attenuation of the 1-D spherical symmetric model agreed with the laser-induced shock waves obtained experimentally. However, the peak pressure and duration time of the shock wave was not the same as the experimental result. Then, the bubble behavior was included in the computation of the shock wave propagation. As for the bubble behavior, Rayleigh-Plesset equation is used. From this computation, pressure wave was obtained which superposed the pressure of the shock wave on the internal pressure of the bubble. Although the duration time of the pressure wave was close to the experimental result, the value of the pressure was almost the same as atmospheric pressure. It is suggested that there is a possibility that phenomenon other than the bubbles is generated such as plasma when the shock wave is generated by focusing the femtosecond pulse laser

A Novel Intraoperative Mapping Device Detects the Thermodynamic Response Function.

Functional activation leads to an increase in local brain temperature via an increase in local perfusion. In the intraoperative setting, these cortical surface temperature fluctuations may be imaged using infrared thermography such that the activated brain areas are inferred. While it is known that temperature increases as a result of activation, a quantitative spatiotemporal description has yet to be achieved. A novel intraoperative infrared thermography device with data collection software was developed to isolate the thermal impulse response function. Device performance was validated using data from six patients undergoing awake craniotomy who participated in motor and sensory mapping tasks during infrared imaging following standard mapping with direct electrical stimulation. Shared spatiotemporal patterns of cortical temperature changes across patients were identified using group principal component analysis. Analysis of component time series revealed a thermal activation peak present across all patients with an onset delay of five seconds and a peak duration of ten seconds. Spatial loadings were converted to a functional map which showed strong correspondence to positive stimulation results for similar tasks. This component demonstrates the presence of a previously unknown impulse response function for functional mapping with infrared thermography.

Effects of Sexed and Conventional Semen Use and Calf Sex on Milk Yield Parameters, Body Weight and Milk Electrical Conductivity in Holstein Cows

This study was designed to determine the effects of semen type and calf gender on milk yield parameters, milk electrical conductivity and milk flow values and postpartum maternal body weight. A total of 265 Holstein cows in the first lactation were used in the study. The effect of sperm type on maternal body weight levels after calving and milk electrical conductivity values was significant (P0.05). Heifers inseminated with sexed semen had higher 100-days milk yield, milk peak yield and postpartum maternal body weight in the first lactation. Milk peak duration was higher in heifers inseminated with conventional semen (P0.05). In conclusion, heifers inseminated with sexed semen had higher maternal body weights, 100-days milk yield, milk peak yields and milk electrical conductivity levels in the first lactation than inseminated with conventional semen

NH-SWE: Northern Hemisphere Snow Water Equivalent dataset based on in situ snow depth time series

Abstract. Ground-based datasets of observed snow water equivalent (SWE) are scarce, while gridded SWE estimates from remote-sensing and climate reanalysis are unable to resolve the high spatial variability of snow on the ground. Long-term ground observations of snow depth, in combination with models that can accurately convert snow depth to SWE, can fill this observational gap. Here, we provide a new SWE dataset (NH-SWE) that encompasses 11 071 stations in the Northern Hemisphere (NH) and is available at https://doi.org/10.5281/zenodo.7515603 (Fontrodona-Bach et al., 2023). This new dataset provides daily time series of SWE, varying in length between 1 and 73 years, spanning the period 1950–2022, and covering a wide range of snow climates including many mountainous regions. At each station, observed snow depth was converted to SWE using an established snow-depth-to-SWE conversion model, with excellent model performance using regionalised parameters based on climate variables. The accuracy of the model after parameter regionalisation is comparable to that of the calibrated model. The key advantages and strengths of the regionalised model presented here are its transferability across climates and the high performance in modelling daily SWE dynamics in terms of peak SWE, total snowmelt and duration of the melt season, as assessed here against a comparison model. This dataset is particularly useful for studies that require accurate time series of SWE dynamics, timing of snowmelt onset, and snowmelt totals and duration. It can, for example, be used for climate change impact analyses, water resources assessment and management, validation of remote sensing of snow, hydrological modelling, and snow data assimilation into climate models.

Estimation of requirements for signal parameters at V-shaped frequency distribution in the mathematical model of a planar phased array antenna

A brief review provides methods of focusing electromagnetic radiation of a flat phased array antenna based on mutually consistent spatial-amplitude-phase-frequency control of the radiated signals and limitations of their potential capabilities arising from various random fluctuations of signal and antenna parameters. The performed statistical study revealed the influence of various random and deterministic changes in the electrical and structural parameters of antennas, control systems for radiated signals with a V-shaped frequency distribution over the aperture of a flat phased array on the peak power level, duration, and repetition period of focused pulses. The parameters of the law of spatial-amplitude-phase-frequency control should be stable for a time equal to the average pulse duration at the output of the emitters when forming a single spatiotemporal pulse, and when forming a sequence of spatiotemporal pulses within duration of this packet of spatiotemporal pulses. The requirements for the accuracy and stability of parameters of the space-phase-frequency signal control law are considered. The analyses of influence of various deviations from the set values of the parameters of the law of spatial-phase-frequency control of emitted signals in the channels of a multi-position system of emitters in the formation of sequences of spatiotemporal pulses is analyzed. It is shown that the influence of errors in the location of the phase centers of the emitters in the direction of radiation does not depend on the distance to the focusing point, but is significant and requires special measures to reduce them. The influence of initial phase setting errors on the characteristics of the generated sequence of spatiotemporal pulses also does not depend on the radiation time. The range of permissible values of the maximum initial phase setting errors behind the aperture of a flat phased antenna array, in which the decrease in the power flux density value does not exceed 10%, should not exceed p/3. The discreteness and random errors in establishing the initial phases of individual radiation sources of a flat phased array equal to p/3 practically do not affect the duration and repetition period of the sequence of spatiotemporal pulses.

Research on the printing mechanism of electrohydrodynamic satellite-free droplets in pulsed voltage

Electrohydrodynamic (EHD) drop-on-demand (DOD) printing in pulsed voltage is a very promising technology for additive manufacturing at the micro- and nanoscale. However, jet/meniscus retraction during DOD printing creates additional satellite droplets, which can lead to blurred print patterns and thus reduced print resolution. In this paper, the mechanism of satellite droplet formation in EHD DOD printing in pulsed voltage is investigated in detail for the first time. At first, the numerical model for EHD printing is established and the correctness and credibility of the numerical results are verified experimentally. After that, the three key operating parameters peak voltage, voltage duration, and bias voltage are analyzed in detail on the formation mechanism of satellite droplets. The operating phase diagram without satellite droplets is proposed. Finally, the electric Bond number BoE and Ohnesorge number Oh are proposed for the detailed analysis of the physical parameters of the liquid on the generation of satellite droplets, and the prediction model of satellite droplet size is presented. The mechanism of satellite droplet formation in EHD printing is revealed, which provides a theoretical basis for the stable printing of satellite-free droplets and advances its application in high-resolution additive manufacturing.

Experimental and Numerical Study of Non-Explosive Simulated Blast Loading on Reinforced Concrete Slabs.

This study presents a non-explosive method for simulating blast loading on reinforced concrete (RC) slabs. The method involves using a newly developed blast simulator to apply a speedy impact load on the slab, which generates a pressure wave similar to that of an actual blast. Both experimental and numerical simulations were carried out to evaluate the effectiveness of the method. The experimental results showed that the non-explosive method can produce a pressure wave with a peak pressure and duration analogous to those of an actual blast. The numerical simulations also showed good agreement with the experimental results. Additionally, parameter studies were conducted to evaluate the effects of the rubber shape, the impact velocity, the bottom thickness, and the upper thickness on the impact loading. The results indicate that pyramidal rubber is more suitable as an impact cushion for simulating blast loading than planar rubber. The impact velocity has the widest range of regulation for peak pressure and impulse. As the velocity increases from 12.76 to 23.41 m/s, the corresponding range of values for peak pressure is 6.457 to 17.108 MPa, and for impulse, it is 8.573 to 14.151 MPa∙ms. The variation in the upper thickness of the pyramidal rubber has a more positive effect on the impact load than the bottom thickness. With the upper thickness increasing from 30 mm to 130 mm, the peak pressure decreased by 59.01%, and the impulse increased by 16.64%. Meanwhile, when the bottom part's thickness increased from 30 mm to 130 mm, the peak pressure decreased by 44.59%, and the impulse increased by 11.01%. The proposed method provides a safe and cost-effective alternative to traditional explosive methods for simulating blast loading on RC slabs.

Estimation of Surface-Subsurface Water Balance in Lower Tapi River Basin Using Gridded Data and Station-Based Observed Data

ABSTRACT Water is an essential resource. An understanding of catchment water balance is crucial to ensure water availability in the region. Hydrological models are credible tools for water balance assessment of a region. These models are data intensive. The traditional hydrological modeling approach relies on station-based observed data. The availability of sufficient long-term consistent observed data is often limited. On the other hand, climate reanalysis data for a long timeperiod is available from multiple data sources. This study estimates runoff characteristics for Lower Tapi River Basin in western India, with the help of a Soil Conservation Service Curve Number method. The catchment water balance in terms of runoff, baseflow, and recharge at sub-basin scale is worked out with the help of station-based and climate reanalysis datasets. The model output are calibrated against observed river gauging data. A reasonable fit between model-simulated and observed runoff is obtained in terms of duration and magnitude of runoff peak. Tested model is applied to future climate scenarios. The simulations show an increase in surface runoff, recharge, baseflow and total runoff for future time period. Results reveal that climate changes have significant impact on hydrology of the basin.