Duration Of Healing Research Articles

Design Considerations, Formulation Approaches, and Strategic Advances of Hydrogel Dressings for Chronic Wound Management.

Wound healing is a complex and dynamic physiological process consisting of a series of cellular and molecular events that initiate immediately after a tissue lesion, to reconstruct the skin layer. It is indubitable that patients with chronic wounds, severely infected wounds, or any metabolic disorder of the wound microenvironment always endure severe pain and discomfort that affect their quality of life. It is essential to treat chronic wounds for conserving the physical as well as mental well-being of affected patients and for convalescing to improve their quality of life. For supporting and augmenting the healing process, the selection of pertinent wound dressing is essential. A substantial reduction in healing duration, disability, associated cost, and risk of recurrent infections can be achieved via engineering wound dressings. Hydrogels play a leading role in the path of engineering ideal wound dressings. Hydrogels, comprising water to a large extent, providing a moist environment, being comfortable to patients, and having biocompatible and biodegradable properties, have found their success as suitable wound dressings in the market. The exploitation of hydrogels is increasing perpetually after substantiation of their broader therapeutic actions owing to their resemblance to dermal tissues, their capability to stimulate partial skin regeneration, and their ability to incorporate therapeutic moieties promoting wound healing. This review entails properties of hydrogel supporting wound healing, types of hydrogels, cross-linking mechanisms, design considerations, and formulation strategies of hydrogel engineering. Various categories of hydrogel wound dressing fabricated recently are discussed based on their gel network composition, degradability, and physical and chemical cross-linking mechanisms, which provide an outlook regarding the importance of tailoring the physicochemical properties of hydrogels. The examples of marketed hydrogel wound dressings are also incorporated along with the future perspectives and challenges associated with them.

Cancellous compression bone grafting using headless screw as a strut in scaphoid nonunion by a single volar approach

PurposeAn array of fixation and grafting techniques for scaphoid nonunion have been described over time, achieving varied results pertaining to union and scaphoid alignment. The aim of this study was to check for union rates and correction of scaphoid parameters achieved by our technique of using screw as a strut and cancellous compression grafting harvested from the distal radius by a single volar approach.MethodsRetrospective analysis of all patients operated by the said technique was done from 2013 to 2019. Thirty-eight patients including 36 males and two females in the age range of 20–56 years were analyzed. Union rates, change in scaphoid alignment parameters and graft site characteristics were documented.ResultsOf the patients analyzed, 5/38 were nonunions of proximal pole, 19/38 of waist and 14/38 were of distal pole which included nonunions of cystic type or with humpback deformity. Patients were followed up for an average of 22.2 months and union was achieved in all cases with a mean period of 15.7 ± 3.7 weeks. There was significant improvement in the scaphoid alignment postoperatively. One case of implant migration and one case of scaphoid nonunion advanced collapse were noted. The mean duration of donor site healing was noted to be 16.9 ± 2.5 weeks except two outliers which took longer time. There were no cases of donor site fracture or other complications.ConclusionUnion rates, correction of scaphoid parameters and minimal complications justifies this technique as a novel one in the management of scaphoid nonunion at all levels, with minimal donor site morbidity and attained by the single volar approach.

Prediction of Functional Outcome of Surgical Treatment in Danis-Weber Type-C Closed Ankle Fracture Using AOFAS Ankle Hind Foot Score in a Tertiary Care Hospital

Background: Fracture of the ankle is the most common fracture involving joints. Being a weight-bearing joint maximum thrust passes through it. It is a complex weight-bearing joint and is subjected to many different types of injury. Successful treatment will allow early mobilization to avoid complications. AOFAS Ankle Hind foot score is the most commonly used tool to measure this outcome. Objective: To assess prediction of functional outcome of surgical treatment in Danis-Weber type-C closed ankle fracture using AOFAS Ankle Hind Foot Score. Methods: A prospective observational study was carried out in Monno Medical College and Hospital, Manikganj, from June 2022 to December 2022. A total of 32 patients with Danis-Weber type-C ankle fracture were taken in this study. All the patients were initially managed by analgesic and short leg posterior slab. After admission, all were treated by ORIF with small DCP for fractured fibula and ORIF by two 4mm cannulated cancellous screws for fractured medial malleolus. Operations were done within 4 days to 14 days. The average follow up was 24 weeks. The outcome was assessed by the AOFAS score. Results: The mean age was 34.68+10.79 years with a male predominance, 23 (71%). Most of the patients, 14 (44%), were service holder. Right-sided injury, 20 (63%), were more than left. The main cause of injury was RTA, 22 (69 %), and the commonest mechanism of injury was pronation external rotation, 37 (84%). Syndesmotic injury was present in 28 (88%) cases. The mean duration of hospital stay was 14+2.68 days. Superficial infection was in 2 (6%) patients. The mean AOFAS pain score at 12th and 24th weeks follow up were 29.21+6.18 and 34.3+45.64, which was significant (p-.0005). The mean duration of radiological healing was 13.34+1.56 weeks. The mean dorsiflexion and plantar flexion at 12th weeks follow up was respectively 8.81±1.59 and 43.18+4.70; and 24th weeks follow up was respectively 10.87±1.43 and 51.25+1.11, which was significant .......

Effect of claw blocks on the healing duration and lesion severities of claw lesions in lame cows in Western Thailand.

Lameness is a major complication in dairy cattle affecting health and milk production. Several factors are found to contribute to this condition and specific treatments are required, including the process of claw trimming. The elevation of the claw, such as with the application of a claw block, was reported to be beneficial in the more severe cases. This study aimed to determine the efficiency of a claw block on claw lesions of lame cows in dairy farms in Western Thailand. Locomotion scores of 376 dairy cows were determined by a veterinarian using a scale of 1-5 (1 = normal; 5 = severely lame) at the time of the visit. Cows with a score of 3 or greater were defined as clinically lame. In total, 134 clinically lame cows from 11 dairy farms in the Kanchanaburi and Ratchaburi provinces were included in the analysis. Claw lesions included a white line abscess, bruised sole, sole ulcer, sole abscess, white line separate, and double soles. Wooden or rubber claw blocks were applied to the unaffected claw of the same hoof as the injured claw of 116 cows, which were classified as the treatment cases, and 18 cows were left untreated and classified as the control cases. Each cow was checked on every week of the healing process for 2 months unless the cow was culled earlier. Survival analysis was based on the Kaplan-Meier estimator and Cox Proportional Hazard regression. The median healing time for lame cows with and without claw blocks was 21 and 36 days, respectively. After adjusting for the lesion severity and type, the lame cows with and without a claw block had hazard ratios of 2.16 and 3.08, respectively. The healing times between the four lesion types in cows with a claw block were not significantly different. The healing time was longer in lame cows, with a severity score of 4. The results from this study reveal that the treatment of lame cows with claw blocks promoted the healing capacity of claw lesions after claw trimming.

Compare the Mean Duration of Healing with Sodium Carboxylic Methyl- Cellulose Silver Dressing Versus Standard Petroleum Gauze Dressing for Management of Second-Degree Burns

Introduction: Burn injury is one of the most devastating and serous form of trauma that man sustains. Millions of people all over the world are hospitalized each year for treatment of burns and thousands die. It is estimated that in UK alone 10000 burn victims are hospitalized each year and 700 die. Objective: To compare the mean duration of healing with sodium Carboxylic methyl- cellulose silver dressing versus standard petroleum gauze dressing for management of second-degree burns. Material and methods: A total of 100 patients of second-degree burns were selected for this study. Clinical examination of patients was done to find out the degree of burns. In group A, Aquacel Ag dressing was applied. In group B, petroleum gauze dressing was applied. Patients were evaluated on each visit when dressing was changed for complete healing. Results: The mean age of the patients was 33.4±19.2 years. Duration of healing when compared in both the groups its showed that average time of healing in group A was 10.38+2.71 while in Group B it was 13.48+5.26SD and it showed significant difference with p-value=0.000. Practical Implications: This study will help to find the best method used for healing in second-degree burns. Conclusion: Mean duration of healing with sodium Carboxylic methyl-cellulose silver dressing was less than petroleum gauze dressing for management of second-degree burns. Keywords: Burn, Injury, Tissue, Wound, Healing, Management, Dressing

Vitamin D as adjuvant therapy for diabetic foot ulcers: Systematic review and meta-analysis approach

Diabetic Foot Ulcer (DFU) is a combination of neuropathy and ischaemia on diabetic patient's lower limbs. It has a high burden of limb amputation rate, mortality rate, disability, economic burden, and lower quality of life on diabetic patients. It took mostly 3-6 months and up to 1 year for DFU to heal. DFU patients also have an increased risk of vitamin D deficiency. Meanwhile vitamin D has effects on immune response, insulin secretion, and sensitivity. The long duration of DFU healing is a problem for the patient's health, job, income, quality of life, economy and healthcare. Therefore, we aim to conduct a meta-analysis to assess reliability of vitamin D supplementation on diabetic foot ulcer clinical outcome. We conducted systematic literature search according to PRISMA guideline on Cochrane Library, PubMed, Google Scholar, ProQuest, EBSCO and ScienceDirect from 16 until 24 June 2022. Effect of vitamin D supplementation on diabetic foot ulcer patients was analyzed with a comprehensive meta-analysis tool. Pooled ulcer area, total cholesterol, triglyceride, C-reactive protein, HbA1c, and fasting plasma glucose assessed with 95% confidence intervals were estimated using fixed-effects or random-effects models. We included 4 papers with 197 people as sample reporting vitamin D capability as treatment for DFU patients. The pooled analysis showed significant differences in ulcer area, serum Vitamin D, Total Cholesterol, Fasting Plasma Glucose, Triglyceride, C-Reactive Protein, and HbA1c. Insignificant results on Erythrocyte Sedimentation Rate and High Density Lipoprotein levels. Vitamin D supplementation is beneficial to be given as adjuvant treatment for diabetic foot ulcer. It may fasten the wound healing and decrease the burden caused by diabetic foot ulcers.

Assessing the Efficacy of Hyperbaric Oxygen Therapy on Facelift Outcomes: A Case-Control Study Comparing Outcomes in Patients With and Without Hyperbaric Oxygen Therapy.

Wound healing remains among the most concerning complications in aesthetic surgery. The use of hyperbaric oxygen therapy (HBOT) is an accepted method of supporting wound healing. The aim of this study is to assess the role of HBOT in postoperative healing and complication rates following facelift surgery. This case-control study comprised facelift patients who received HBOT and those who did not between 2019 and 2022. Data were extracted from the patients' medical records, with the primary outcomes being the presence of complications, wound-healing duration, and patient satisfaction. The authors recruited 20 female patients who underwent facelift for this study, with 9 patients in the HBOT group and 11 patients in the control group. The average number of HBOT sessions received was 7.22, and each session lasted an average of 78 ± 5 min. The duration of wound healing in the HBOT group ranged from 7 to 30 days (mean of 13.3 days), whereas the control group ranged from 6 to 90 days (mean of 36.9 days). This indicates a statistically significant shorter time to wound healing in the HBOT group compared to the control group (P < .001). Future prospective randomized controlled trials with larger sample sizes and blinding are needed to further evaluate the potential benefits of HBOT in the postoperative period. Nonetheless, our findings suggest that HBOT may be a promising adjunctive therapy for patients undergoing facelift surgery.

The Efficacy of Combined Olive Leaf and Curcumin Extract on Healing Human Papillomavirus: A Randomized Clinical Trial

Background. Genital warts are sexually transmitted diseases for which there is no definitive cure. This study aimed to determine the effect of the combination of olive leaf extract and curcumin on the number of lesions and the duration of recovery in patients with external anogenital warts. Methods. This study is a three‐blind randomized controlled clinical trial conducted in 2020. In this study, women with external anogenital warts were enrolled by the consecutive nonprobability sampling method and then assigned by stratified block randomization to two groups: placebo (n = 28) and intervention (n = 26). In the intervention group, the combined olive leaf and curcumin extract was applied topically three times a day until recovery and up to 12 weeks. Routine treatment was administered to both groups in addition to the interventions. The number of warts, the duration of recovery, and the severity and duration of treatment side effects were assessed in all participants. Results. The results showed that the mean number of warts was significantly lower in the intervention group (5.65 ± 5.223) than in the placebo group (7.61 ± 5.245) from the fifth day of treatment onwards (p = 0.027). The mean duration of recovery in days in the intervention group (14.73 ± 9.735)) was significantly less than the placebo group (34.25 ± 18.863) (p = 0.001). In addition, there was no significant difference between the two groups in the frequency of drug side effects such as burning (p = 0.083), redness (p = 0.413), and itching (p = 0.706). The intervention group experienced side effects for a shorter duration of time (1.50 ± 1.924) compared to the placebo group (4.93 ± 8.366) (p = 0.043). Conclusion. The combined 10% olive leaf and curcumin extract can be effective in reducing the number of warts, duration of healing, and reducing the duration of complications in patients with external anogenital warts and is recommended as a complementary treatment for these patients. This trail is registered with IRCT20200509047350N1

Modified Decompression Technique in the Management of Odontogenic Cystic Lesions

Introduction: Odontogenic cystic lesions requiring conservative management were treated with a novel technique of modified decompression and assessed. Aims and Objective: This study aimed to evaluate the resolution of the lesion, recurrence, and complications in patients treated with the novel modified decompression technique. Materials and Methods: The retrospective study included patients treated with the novel modified decompression technique between 2004 and 2022. The cystic lesions were packed with chlorhexidine acetate gauze dressing (Bactigras), and patients were prescribed a combination of Calcium, Vitamin C, and Vitamin D. Pack was changed periodically until a reduction of at least 80% in the volume of the lesion was achieved. Period of decompression, volume at each follow-up, and lesion size were recorded. In addition, inter-group significance co-relating the size and diagnosis of the lesions with the rate and duration of healing were derived by ANOVA test. Results: OKC, unicystic ameloblastoma, and dentigerous cysts were included, and the follow-up period ranged from one year to eighteen years. 25 cases (83.33%) showed full resolution, whereas five cases (16.17%) showed more than 80% resolution. The period of decompression and the rate of decompression was found to correlate with both the diagnosis and the size of the lesion. Conclusions: The modified decompression technique is superior to traditional decompression with a high rate of resolution of cystic lesions and no recurrence over a long follow-up period.

Treatment algorithm for post sternotomy wound infection - our experience.

Median sternotomy is the most commonly used approach in open cardiac surgery. As in any other surgery, surgical site infections are aknown phenomenon, but morbidity depends on the depth of infection. Superficial wound infections can be managed conservatively; however, deep sternal wound infections need an aggressive approach to prevent disastrous consequence like mediastinitis. Hence, this study was conducted with the aim to classify sternotomy wound infection and to develop atreatment algorithm for superficial and deep sternotomy wound infections. Between January 2016 to August 2021, 25 patients who had sternotomy wound infections were studied. These wound infections were classified as superficial or deep sternal wound infections. Superficial wound infections underwent treatment with diluted vinegar dressings and deep infections underwent treatment with bilateral pectoralis major muscle advancement flaps. Patients were followed up till the wounds healed completely without complications. Patient characteristics, comorbidities, duration of treatment and outcomes of treatment were analyzed. Superficial sternal wound infection patients responded favorably to diluted vinegar dressings and deep sternal wound infection patients to pectoralis major muscle advancement flaps. Average time duration of healing for superficial and deep wound infections was 66.2 days and 18 days respectively. None of the patients had an increased severity of infection or re-dehiscence following treatment and during follow-up. Relatively conservative approach using diluted vinegar (1% acetic acid) dressing for superficial sternal wound infections was efficacious, whereas aggressive debridement and bilateral pectoralis major advancement muscle flaps for deep sternal wound infections are necessary for favorable outcomes. However, more studies are needed to ascertain this treatment algorithm.

Treatment Management of Diabetic Wounds Utilizing Herbalism: An Overview.

Diabetes Mellitus, commonly known as DM, is a metabolic disorder which is characterized by high blood glucose level, i.e., chronic hyperglycemia. If it is not managed properly, DM can lead to many sever complexities with time and can cause significant damage to the kidneys, heart, eyes, nerves and blood vessels. Diabetic foot ulcers (DFU) are one of those major complexities which affect around 15-25% of population diagnosed with diabetes. Due to diabetic conditions, the body's natural healing process slows down leading to longer duration for healing of wounds only when taken care of properly. Herbal therapies are one of the approaches for management and care of diabetic foot ulcer which utilizes the concept of synergism for better treatment options. With the recent advancement in the field of nanotechnology and natural drug therapy, a lot of opportunities can be seen in combining both the technologies and moving towards a more advanced drug delivery system to overcome the limitations of polyherbal formulations. During the writing of this document, the data was derived from existing original research papers gathered from a variety of sources such as PubMed, ScienceDirect, Google Scholar. Hence, this review includes evidences about the current practices and future possibilities of nano-herbal formulation in treatment and management of diabetic wounds.

Contemporary Multimodal Surgical Therapy Allows for Durable Healing of Venous Stasis Ulceration

Chronic venous disease has a high prevalence in the United States, with 1% to 1.5% of the population estimated to have healed or active ulcers. Surgical therapy often involves a variety of procedures aimed at treating underlying superficial and deep venous pathology. We sought to evaluate the effects of a contemporary, multimodal approach to surgical therapy of advanced venous disease.

Application of Electrospun Nanofiber in Wound Healing: Trends And Recent Patents Analysis

Abstract: A full-thickness open wound with loss of residual cells for regeneration does not heal spontaneously and takes a long duration for complete healing. Sometimes, this results in scarring of the skin and significant disability. A scaffold that provides a 3D framework for cell signaling, attachment, and proliferation is essential for the rapid closure of a full-thickness wound. Nowadays, the electrospun nanofiber is the most widely employed formulation in wound healing. The current study analyzed a patent trend analysis of electrospun nanofiber's application in tissue regeneration. The patent search was conducted using open-source patent databases like The Lens and Patentscope. Two hundred thirty-one patent records were found with the keywords and exported from the database for January 1, 2010, and December 31, 2021. After the initial screening, 24 patent documents were shortlisted for in-depth analysis. China, the USA, European Countries, Korea, and Australia lead this patent filing field. The top applicants are either private companies or academic institutions. The last ten years of patents were analyzed in terms of Patent-Applicant, Patent- Inventors, Patent-Owners, patent filed, published and granted. In the top ten Assignee, Marine Essence Bioscience Corp (US) topped the list. The most-recorded IPC class is A61L15/44, a subgroup of A61L15, and it is related to the chemical aspects of, or use of materials for, bandages, dressings or absorbent pads. In the end, some relevant patent was analyzed based on their citation by other patents and non-patent literature. From patent trend analysis, it was observed that the electrospun nanofiber would provide an attractive area for research in tissue regeneration.

The battle trauma of the esophagus

Objective. Estimation of efficacy of diagnosis and methods of treatment in patients, suffering the battle trauma of the esophagus.&#x0D; Materials and methods. In the Division of Thoraco–Abdominal Surgery of the Shalimov National Institute of Surgery and Transplantology the treatment of 7 patients with penetrating esophageal wounds was conducted. In 6 (85.7%) patients the penetrating gun–shot woundings were diagnosed, and in 1 (14.3%) patient – the closed thoracic trauma. Shrapnel woundings prevailed over the bullet woundings, occurring in5 (71.4%) and 2 (28.6%) patients, accordingly. Esophageal trauma as isolated affection, caused by the gun–shot penetraiting wounding was extremely rare – in 1 (14.3%) patient. Efficacy of diagnosis and surgical stationary treatment of esophageal trauma, caused by foreign bodies, was estimated, as well as the terms of the esophagus integrity restoration.&#x0D; Results. In 2 (2.6%) patients with pleural empyema open toracotomy access with further pleurectomy, pulmonary decortication, and restoration of the esophageal wall integrity was applied. In 4 (57.2%) patients thoracoscopy, pleurectomy, pulmonary decortication, and esophageal suturing were conducted.&#x0D; Intraoperatively in 6 (85.7%) patients the endoscopic vacuum therapy system was installed locally in the damaged esophagus portion. In 1 (14.3%) patient with local pleural empyema the treatment tactics consisted of the pleural cavity drainage under ultrasonographic control plus endoscopic vacuum therapy. For achievement of its optimal efficacy the pressure value was supported in range from 100 to 120 mm Hg. Endoscopic vacuum system was changed every 4 – 5 days. Average duration of the fistulas healing have constituted 1mo.

The Effect of Giving Boiled Chicken Eggs on the Healing of Perineal Wounds for Postpartum Mothers in the Independent Practice of Midwife Sumiariani in 2021

Postpartum infections still play a role as the main cause of maternal death, especially in developing countries like Indonesia. The aim of this study was to determine the effect of giving boiled chicken eggs on perineal wound healing in postpartum women. The type of research used in this study was a Quasi Experiment with a population of postpartum women with perineal wounds with a total sample of 10 respondents, 5 respondents (intervention group) and 5 respondents (control group). The results of the study showed that the average length of days healing of perineal wounds in postpartum women in the intervention group (given boiled eggs) was 5.4 days. The mean duration of perineal wound healing in the control group was 10.6 days. There is an effect of giving boiled chicken eggs on perineal wound healing in postpartum women with a p-value of 0.000 &lt;0.05.

Evaluation of amnion versus calcium alginate as split-thickness skin graft donor site dressing: A randomised controlled trial

Background: Split-thickness skin graft (STSG) covers patient’s primary wound, but, at the expense of a donor-wound which heals by secondary intention. This study evaluated the efficacy of amnion and calcium alginate dressings at STSG donor sites in terms of healing duration, patient comfort and incidence of infection.&#x0D; Patients and methods: An open label randomised control trial was conducted during October 2018 to May 2019. Total 60 patients, aged 20-45 years, were randomly allocated to two equal groups. Amnion was applied to 30 donor sites in Group A and calcium alginate in 30 donor sites in Group B. Patients were phone-called on 1st, 3rd and 7th post-operative days and donor site pain scored using numerical rating scale. Donor site was opened on 10th postoperative day and signs of infection assessed. Lastly, the day on which donor site healed, revealing an epithelialized wound, was noted.&#x0D; Results: Group A included 30 patients (11 females, 19 males) having mean age of 31.23 years and Group B included 30 patients (12 females, 11 males) having mean age of 31.30 years. Average pain scores on 1st, 3rd and 7th post-operative days were 7.6, 6.6 and 4.4 in Group A and it was 8.2, 6.5 and 4.4 in Group B. Two cases of amnion, 4 of calcium alginate got infected. Average healing duration was 11 days in Group A; and it was 14 days in Group B (p-value = 0.000).&#x0D; Conclusion: Amnion shows quicker healing and better pain control than calcium alginate.

EFEKTIVITAS REBUSAN DAUN SIRIH HIJAU TERHADAP PENYEMBUHAN LUKA PERINEUM PADA IBU NIFAS DI DESA MOJONGAPIT JOMBANG

Cases of infection during the puerperium are caused by infections that are localized in the birth canal and the most common cause, more than 50%, are anaerobic Streptococcus bacteria which are actually not pathogenic. Green betel leaves are known to have antiseptic and antibacterial properties. The research method is quasi-experimental, the population taken in this study was postpartum mothers who were in the village of Mojongapit, Jombang district, with a total of 24 respondents. The technique used in sampling is purposive sampling. The inclusion criteria for sampling were as follows: postpartum mothers who experienced second and third degree perineal injuries with physiological delivery, mothers who were willing to become respondents. Analysis using the Mann - Whitney Test. The results showed that the healing time for perineal wounds in postpartum mothers who were given boiled green betel leaves was 4 - 6 days. The length of time for perineal wound healing in postpartum women who were not given boiled green betel leaves was 5-9 days. Differences in the duration of perineal wound healing in postpartum women who were given green betel leaf decoction was 0.4 times faster than postpartum women who were not given green betel leaf decoction&#x0D;

The Antimicrobial and Healing Effect of Scrophularia striata Boiss Hydroalcoholic Extract on First- and Second-Grade Pressure Wounds in Patients with Brain and Spinal Cord Injury: A Randomized Clinical Trial.

This double-blind clinical trial study was performed on grade 1 and 2 pressure wounds in 120 patients with cerebral-spinal cord lesions. The patients were randomly divided into four groups (n = 30). Topical treatments in all groups were performed twice a day. These groups included experiment 1 (SHE + phenytoin), experiment 2 (SHE + SHE), control (phenytoin + phenytoin), and placebo (eucerin + phenytoin). After evaluating the effect of SHE on wound healing, its antibacterial activity was determined by the standard agar well diffusion method. Patients in each group in this study did not significantly differ in demographic and clinical variables. Complete wound healing by the 10th day of the intervention occurred in 63%, 100%, and 27% of patients in experimental 1, experimental 2, and control groups, respectively. In contrast, the placebo group had no complete wound healing until the 10th day. Topical application of SHE, twice a day in the experimental 2 groups, had a higher potency to heal wounds and reduce the duration of complete wound healing in patients compared with other groups. SHE, as a novel treatment option, has good potential to accelerate the healing of first- and second-degree pressure wounds in patients with brain-spinal cord injuries.

Outcomes of coblation tonsillectomy versus bipolar electrocautery tonsillectomy in pediatric population

BackgroundBipolar electrocautery tonsillectomy has been the preferred technique for many otolaryngologists, yet coblation tonsillectomy is gaining popularity in the current practice. This study aims at comparing both techniques in terms of pain, bleeding, and healing.ResultsA total of 120 patients were randomly divided into two equal groups. Overall mean pain score associated with coblation tonsillectomy was statistically less than that caused by bipolar electrocautery throughout the follow-up period (p < 0.001). The difference in pain duration was statistically longer for the bipolar group. The incidence of postoperative hemorrhage—both reactionary and secondary—was statistically higher in the bipolar group. Coblation tonsillectomy showed statistically shorter duration of healing (p < 0.001).ConclusionsCoblation tonsillectomy is associated with less pain severity and shorter pain duration, fewer bleeding incidents, and more prompt healing.

Relationship between Characteristics of the Wound and Healing Duration among Patients Treated during Home-Visits.

In humans, wound healing is a vital but complex process governed by chronological yet overlapping stages, such as hemostasis, inflammation, proliferation, and remodeling. Because of the complexities of wound healing, it is prone to pausing at multiple levels. Wound healing can potentially be influenced by factors that affect cellular functions and physiologic responses. This research aimed to investigate the relationship between wound healing duration and demographic properties and characteristics of wounds among patients treated during home visits in Erbil, Iraq. To this end, a longitudinal correlational quantitative design was employed in the current study. A random sample of about 101 chronic wounds was found in 77 patients of both genders selected from all ages during home visits for around four years in Erbil. The professional nurse applied nursing management according to the nursing plan during home visits until the wound recovered. The total duration of wound healing was calculated and documented for each wound. Seventy-seven patients participated in the current study, with their mean±SD age being 58.02±16.29 years, ranging from 19 to 89. The median age was 60. More than half of the sample (54.5%) were ≥60 years, and 62.3% were males. Less than one-third of patients (31.2%) were of normal weight, 93.5% were married, 37.7% were housewives, and 35.1% were illiterate. Regarding the duration of wound healing, in more than one quarter (26.7%), it was delayed (took more than three months for healing). The longest mean healing time (20.06 weeks) was for pressure ulcers (P<0.001), which was significantly higher than all the mean healing times of other types of wounds. The study showed a significant (P=0.011) association between the mean healing time and the anatomic location of wounds, revealing that the highest mean healing time was for wounds located in the trochanteric area (21.10 weeks) or the sacrum (18.25 weeks). A significant association (P=0.002) was also detected between the mean healing time and the edge of the wound, with the highest mean healing time (18.64 weeks) found in wounds with undermined edges. Furthermore, the mean healing time was significantly higher among those with infected wounds (14.59 weeks) than the mean (6.50 weeks) among those with no infection (P<0.001). In conclusion, wound healing progression is an important but complicated process that healthcare providers use for patients during home visits. It is divided into phases, including hemostasis, inflammation, proliferation, and remodeling. The current study revealed that the healing time was affected by the anatomical site of the wound and took longer in pressure ulcers, undermined edge wounds, and infected wounds.