The article discusses the issues of reuse of drainage and waste water in the middle reaches of the Syrdarya River. According to the results of the research, it was revealed that the salt balance of the soils of cotton and corn fields in the aeration zone (0-2 m) has different indicators. In the irrigation variant with drainage water up to 6.0 g/l, the soil was saturated by the end of the growing season with salts in the amount of 26.4 t/ha under cotton crops and 63.8 t/ha under corn, when irrigated with river water, a favorable salt regime was observed, i.e., salts were removed to the underlying horizons or drainage from the upper layer in the amount of 81.3 t/ha under cotton and 42.6 t/ha under corn. For desalination of drainage and waste water, crushed natural saline plants (Glycyrrhiza glabra, Alhagi, and others) and a 20 % concentration of glauconite clay or phosphogypsum, which are diluted with drainage and waste water, are used in the complex. The resulting reclamation complex allows reducing the mineralization of drainage and waste water to standard indicators.
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