The purpose of this study was to investigate the relationship between respect for life of buddhism and organ donation. The research problems of this study are as follows. First, what are the general characteristics of organ donors? Second, what are the motives for organ donation pledges? For this study, the attitude toward organ donation, the commitment attitude toward organ donation, the subjective knowledge about organ donation, and the issue involvement for organ donation were surveyed and questionnaires composed of open-ended questions about the motives for organ donation pledges were conducted. The data of 139 Buddhist believers were collected and analyzed by frequency analysis and descriptive statistics and the responses of qualitative questions were analyzed using CQR-M. The results of the study are as follows. First, as a result of examining the general characteristics of organ donors, The minimum age of organ donors is 20 years old, the maximum age is 63 years, and the mean age is 43.59 years, and the standard deviation is 13.057. In the case of gender, the female pledge is more than the male, and more than half are married. In terms of health status, normal, good, and very good were more than 90% of the total responses, and their health status was perceived as good. As a result of looking at the current residence type, living together with their spouse, parents, children, or spouse and children, spouse and parents was about 90%. In the case of the organ donation pledge period, 2008 was the oldest, and in particular, the number of pledges in 2015, 2016 and 2017 increased significantly. As a result of examining the descriptive statistics on the psychological characteristics related to organ donation by organ donors, organ donation attitude, organ donation pledge attitude, subjective knowledge of organ donation, and the issue involvement showed that the mean was all above normal(3.0). Second, as a result of searching for the motivation of organ donation pledge, six sub-categories were derived; publicity and providing sufficient information, connection with Buddhist monk, connection with Buddhism, impression from life of organ donated people, genuine respect for life, and mercy practice. In terms of frequency, practice mercy was the most, followed by publicity, sufficient information, and genuine respect for life. It is meaningful that this study provided basic information to enable organ donation activities based on Buddhism