Entrepreneurship has a strategic role including the economic development of a country as measured by Gross Domestic Product (GDP). The purpose of this study is to analyze in depth the strategic role of entrepreneurship in development which is reviewed in an Islamic economic approach. Qualitative research methods used in this study with a descriptive analysis approach. The data collection technique is carried out in a documented manner using Gross Domestic Product (GDP) data for the 2018-2021 period which is sourced from published data from the Central Statistics Agency (BPS). The step in data analysis is carried out by comparing the role of entrepreneurship in development in other countries such as America, China, India, England, South Korea, France, Africa and Colombia with the role of entrepreneurship in Indonesia for later analysis. depth which can then be concluded. The results show that the role of entrepreneurship in Indonesia is able to contribute to GDP up to 60%-61%. Whereas in the Islamic economic approach, entrepreneurship is seen as not only aiming to gain profit, but it contains the values of ta'awun to create jobs, reduce unemployment and alleviate poverty through activities to prosper the earth with innovation and creation with the aim of achieving falah and mashlahah.