Mine drainage pump is the most important load in mining which requires high reliabilitywhen operating. Currently, the power supply of a mine drainage pump is connected to the same powerline with many nonlinear loads, and is equipped with power electronic converters, which makes thepower supply nonsinusoidal. During the working process of a mine drainage pump, the load-carryingfactor often changes, and many types of failures occur, among which single-phase voltage loss is themost common problem. In the case of a nonsinusoidal power supply, if a single-phase voltage lossoccurs in different load modes, it will greatly affect the working mode of the mine drainage pumpleading to influences on the working efficiency, the life of the pump, and sometimes it is necessary torecalculate the protection parameters. This paper studies the influence of single-phase voltage loss andload carrying mode on the working mode of mine drainage pump motor in case the of nonsinusoidalpower supply. Research results show that, in the case of nonsinusoidal power supplied with single-phasevoltage loss, copper losses in the rotor and stator circuits increase with increases in voltage totalharmonic distortion (THD) and load-carrying factor, 5th order reverse harmonic increases copper loss inasynchronous motor the most, and higher harmonic components have less effect on copper loss in themotor. At the same time, the speed ripple decreases with the increase of the motor load factor anddecreases in the presence of the 5th order negative sequence harmonic, and increases significantly in thepresence of the 7th order positive sequence harmonic. 5th order negative sequence harmonic increases,the torque ripple increases, while the 7th order positive sequence harmonic reduces the torque ripple inthe case of single-phase voltage loss. The results of the paper will help improve the operationalefficiency of the mine drainage pump in Vietnam's mines.