The proliferation of the ambient environment with many wireless communication infrastructures has constituted a source of concern, at least from health point of view. Hence, there is a need for the investigation of electromagnetic wave interaction with human tissue. This paper models electromagnetic wave propagation at the free-space-human tissue interface, in an attempt to understand how electromagnetic waves interact with the human skin. Maxwell’s equations were used to derive the governing equations of propagating electromagnetic waves in free space while the solution of the boundary-value problem arising from the incident electromagnetic wave at the free space-human tissue interface was found through the use of appropriate boundary conditions. The solution led to the emergence of four Fresnel equations, a pair each for perpendicular and parallel polarizations of the incident wave, at the boundary. Through the use of the Fresnel equations obtained, components of the incident electromagnetic wave power at the boundary can be quantified. Typical profiles of the normalized reflected and absorbed powers at the free space-human skin interface at 28, 60, and 73 GHz were computed, using measured values of permittivity of human tissue. It is found that the total absorption of the power of the incident wave by the human skin occurs when the angle of incidence is between 690 and 770 for the three frequencies used. This is irrespective of the polarization of the incident wave. Information on such distinct angles of incidence for total absorption of power does not appear to exist in the literature as they represent new, previously unreported facts in the existing body of research. Furthermore, computed profiles of reflected power versus incidence angle displayed here, for perpendicular polarization, demonstrate strong alignments with established literature, thus reinforcing the credibility of the results presented in this paper.