In this paper, the low-cycle reciprocating load test was carried out on four-limb concrete-filled steel tubular (CFST) lattice columns with different slenderness ratios and axial compression ratios, and the seismic performance was studied. Two performance indicators, namely damage and hysteretic energy dissipation, were defined as the objective functions, and the axial compression ratio was used as an optimization variable to perform the multi-objective optimization analysis of four-limb CFST lattice columns. Optimization using the max–min problem approach aims to optimize the axial compression ratio to minimize damage and maximize the dissipation of hysteresis energy. The seismic performances before and after optimization were determined using a restoring force model and were evaluated by the finite element method under different axial compression ratios. The results show that, under low-cycle reciprocating loads, the load–displacement hysteresis curve is a bow shape (Members 1 and 2), inverse S-shape (Member 3), and approximate shuttle shape (Member 4). Through multi-objective optimization, the optimized axial compression ratio is 0.25 and the finite element analysis indicates that the optimal seismic performance is at an axial compression ratio of 0.25. Through the optimized design, the maximum horizontal load of lattice columns, the elastic stiffness, the dissipation capacity, and the seismic performance are all improved, under the premise of satisfying the structural safety.
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