The importance of timely detection, classification and response to anomalies on petroleum products pipeline (PPP) have attracted pragmatic researches in recent times. There is need for efficient monitoring and detection of activities on PPP to guide leak detections and remedy decisions. This paper develops an intelligent hybrid system, driven by discrete event system specification (DEVS) and adaptive neuro-fuzzy inference system (ANFIS) for detection and classification of activities on PPP. A dataset comprising 330 records was used for training, validation and testing of the system. Result of sensitivity test shows that inlet pressure, inlet temperature, inlet volume and outlet volume have cumulative significance of 71.72% on flowrate of PPP. Hybrid learning algorithm was observed to converge faster than the back propagation algorithm in the detection of pipeline activities. ANFIS hybrid learning algorithm with training and testing errors of 0.11980 and 0.010233 yielded a correlation of 0.916 between the computed and the desired output and produced optimal consequent parameters to boost the intelligence of DEVS. A testing error of 0.0303 was observed in the evaluation of DEVS-ANFIS system on 33 test data sample, 32 precise detections were made with one incorrect detection, this gives 96.97% level of confidence in the DEVS-ANFIS model for detection, classification and localization of PPP activities.