This paper investigates the fire performance of large-scale steel reinforced concrete (SRC) column to reinforced concrete (RC) beam planar frames by a series of fire resistance tests. The testing parameters included beam load ratio, column steel ratio and column dimension. The test results indicated that, in fire condition, the SRC column to RC beam frame exhibited two primary failure modes: beam shear failure and column compression failure. In the case of beam shear failure, the fire resistance of frame specimens increased as the beam load decreased. In the scenario of column compression failure, out-of-plane failure occurred due to the weak axis of the SRC column being located outside the frame plane. Concurrently, the RC beam displayed significant shear deformation at the ends and notable bending deformation in the middle. The test results indicated that the column cross-sectional size notably influenced the fire resistance of SRC column to RC beam frame, however, the influence of column steel ratio was minimal.