Digital Converter Research Articles

Metals for energy & digital transition in Spain: Demand, recycling and sufficiency alternatives

This study employs Material Flow Analysis (MFA) to comprehensively forecast metal demand in alignment with energy and digital transition policies at the country level, focusing on Spain. Our analysis spans eight technologies and ten metal groups, projecting metal demand and end-of-life recycling by 2050. We apply ambitious collection and recycling rate objectives, providing estimates of primary extraction requirements. We define and evaluate six scenarios targeting circular economy and sufficiency alternatives aimed at reducing primary extraction. Our results highlight electric mobility as the predominant driver of future metal demand, accounting for 54–92 % of cumulative demand for aluminum, copper, manganese, cobalt, nickel, lithium, dysprosium, and neodymium. From a global justice perspective, the 'equitable fraction of global reserves' for lithium and cobalt is surpassed. Ambitious recycling efforts could potentially cover 23–68 % of the cumulative metal demand between 2020 and 2050, while implementing circular economy and sufficiency alternatives might reduce primary extraction requirements by 11–61 %.

Sentiment Analysis of Digital Conversations Related to Myasthenia Gravis by Race/Ethnicity (P10-11.019)

Sentiment Analysis of Digital Conversations Related to Myasthenia Gravis by Race/Ethnicity (P10-11.019)

Building And Perfecting Digital Government in Ho Chi Minh City, Vietnam: The Necessity and Motivation in Today's Businesses

In the context where digital transformation ranks as one of the foremost priorities for technology businesses in Vietnam, the Vietnamese government also places a special emphasis on digital conversion within the framework of the Fourth Industrial Revolution and the synchronized implementation of the National Digital Transformation Program. As a large, modern, and dynamic city, Ho Chi Minh City has swiftly shifted from e-government to digital government, significantly impacting the digital transformation processes of businesses within the city. This presents both a requirement and an opportunity to assert the city's position as a leading center for economics, culture, education, science, and technology in the country. This article endeavors to clarify the necessity, some groundbreaking results, experiences, and requirements imposed on the digital government in driving digital transformation within businesses operating in Ho Chi Minh City today.

An analog to digital converter in a SiC CMOS technology for high-temperature applications

Integrated circuits based on wide bandgap semiconductors are considered an attractive option for meeting the demand for high-temperature electronics. Here, we report an analog-to-digital converter fabricated in a silicon carbide complementary metal–oxide–semiconductor technology now available through Europractice. The MOSFET component in this technology was measured up to 500 °C, and the key parameters, such as threshold voltage, field-effect mobility, and channel-length modulation parameters, were extracted. A 4-bit flash data converter, consisting of 266 transistors, is implemented with this technology and demonstrates correct operation up to 400 °C. Finally, the gate oxide quality is investigated by time-dependent dielectric breakdown measurements at 500 °C. A field-acceleration factor of 4.4 dec/(MV/cm) is obtained by applying the E model.

Enhanced Inclusion through Advanced Immersion in Cultural Heritage: A Holistic Framework in Virtual Museology

In recent years, the digitization of cultural heritage has been favored by significant advancements in specific technologies, such as photogrammetry and three-dimensional scanning. The digital representations of artifacts, paintings, books, and collections, as well as buildings or archaeological sites, has led to the transfer of cultural organizations to the digital space. On the other hand, the rapid development of immersive technologies and the Internet of Things is expected to decisively shape virtual cultural heritage in the coming years. However, this digital transition should expand its impact on most of the population. This article aims to cover the lack of structured methodology in the design and development of inclusive virtual spaces in cultural heritage. This research introduces a holistic framework that is mainly based on the disciplines of virtual museology. The proposed methodology takes into account the advancements in extended reality and the creative industry of computer games. The multisensory approach would lead to advanced immersive experiences, while the multilayered approach of cultural heritage content would enhance accessibility in inclusive virtual spaces. Moreover, this holistic framework could provide evidence from the virtual worlds that could be applied to real cultural heritage organizations.

SOCIALIZATION OF DIGITAL TELEVISION BROADCAST TECHNOLOGY CONVERSION (STUDY REGARDING THE REPRESENTATION OF DIGITAL TELEVISION BROADCAST TECHNOLOGY IN OMNIBUS SHORT FILM)

Omnibus Short Films are a collection of several short films that have the same theme. Omnibus Short Film with the Theme Migrasi TV Analog / Omnibus STB consists of 4 (four) Short Films entitled : TV Ini Kubelikan Untuk Anakku Tapi Istriku Marah-Marah, Ningali TV, Mbayar and Menjarah. This research uses the Social Reality Construction Theory which is a theory from Peter L. Berger and Thomas Luckmann (1966). This research method uses the Charles Sanders Pierce Semiotic Method, to research and analyze film texts. Apart from that, the researcher also carried out communication interactions with various sources, observations, interviews, documents and other materials as evidence or proof, related to the Socialization of Digital Television Broadcast Technology Conversion (Study Regarding the Representation of Digital Television Broadcast Technology in Omnibus Short Films). The paradigm used in this research is constructivist. This research uses a qualitative approach which allows researchers to discuss the research in more depth. The novelty or novelty of this research is the Omnibus Short Film with the Theme Migration of Analog TV / Omnibus STB, as a medium for conveying messages to the public, has shown that the film is able to make the circulation of information through the socialization of the conversion of digital television broadcast technology, faster and evenly distributed in efforts to socialize the conversion of digital television broadcast technology. This means that it has completed Peter L. Berger's Social Reality Construction Theory, namely that all this time Peter L Berger never talked about the media, but then it was the media that led to representation. So the media plays a role as a construction and representation of reality, in the socialization of the conversion of digital television broadcast technology

A novel approach toward optimized image processing using sigma delta modulation

Image processing has widespread uses practically in every branch of science and arts. Processing images is more difficult than processing sound or data as there are more bits in the high pixel quality image. It requires more space to store the image, more bandwidth to transmit it, and more time and resources to process. An image's complexity may decrease if its bit size is decreased. Sigma-delta modulation, or SDM for short, is an alternative method of minimizing data-word length to compression. Digital signal processing (DSP) systems can be made simpler by using the SDM approach, which was first created for analog to digital conversion (ADC). This paper suggests a novel way to use SDM in MATLAB for improved image processing. Consequently, the suggested single-bit SDM-based image arithmetic architecture is tested and compared with the traditional image arithmetic techniques. Additionally, to see the noisy channel influence on the traditional and proposed systems, some statistical metrics are also studied at different noise variance values, such as signal to noise ratio (SNR), mean square error (MSE), and Peak SNR value. The suggested architecture for the SDM-based image arithmetic precisely matches the addition and subtraction results of the conventional design, even yielding a higher SNR and the same Peak SNR as the traditional methods. In contrast, the outcomes of division and multiplication fall within an acceptable range. For better results the over-sampling ratio (OSR), an inherent characteristic of SDM must be increased at the cost of more processing cycles. Therefore, the trade-off between fewer resources, limited transmission bandwidth, and comparatively more cycles is provided by the SDM-based technique.

Scammer Strategies and Social Actions in Online Filipino Transactions

As technology has developed newer and faster forms of communication, the internet has also become a convenient medium for scammers to interact with their targets. Since deception is understudied from a linguistic perspective, this paper investigated the persuasive strategies and linguistic markers of scammers and analyzed the social actions of both scammers and their targets—all of whom are users of the Filipino language. This qualitative study employed digital conversation analysis in analyzing ten conversations between scammers and their targets—all of which were failed scams. The results showed that scammers used emotion, credibility, and logic in persuading their targets. The following linguistic markers were found in their utterances: (1) pronouns that are personal, exclusive, inclusive, noncommittal, impersonal, and ambiguous; (2) negation used for denial, non-existence, refusal, discouragement, inability, loss, contrast, clarification, and correction; (3) emotion words expressing happiness, astonishment or amusement, worry, doubt or fear, shame, regret or inadequacy, and fondness, and lastly, (4) cognitive verbs indicating equivocation, and expression of knowledge or understanding. Furthermore, the social actions of the scammers and the targets were categorized into four sequences that generally involved certain actions: (1) pre-offer (asking about and providing details), (2) insert (expressing doubt and explaining), (3) offer (offering or asking for money/info, and rejecting), and (4) post-offer (insisting, showing aggression, or conceding and retaliating or interrogating). Although all conversations resulted in the targets’ rejection of the scammers’ offer, which undermines social solidarity, dispreference is seen as a beneficial response in conversations involving scams.

GymHydro: An Innovative Modular Small-Scale Smart Agriculture System for Hydroponic Greenhouses

In response to the challenges posed by climate change, including extreme weather events, such as heavy rainfall and droughts, the agricultural sector is increasingly seeking solutions for the efficient use of resources, particularly water. Pivotal aspects of smart agriculture include the establishment of weather-independent systems and the implementation of precise monitoring and control of plant growth and environmental conditions. Hydroponic cultivation techniques have emerged as transformative solutions with the potential to reduce water consumption for cultivation and offer a sheltered environment for crops, protecting them from the unpredictable impacts of climate change. However, a significant challenge lies in the frequent need for human intervention to ensure the efficiency and effectiveness of these systems. This paper introduces a novel system with a modular architecture, offering the ability to incorporate new functionalities without necessitating a complete system redesign. The autonomous hydroponic greenhouse, designed and implemented in this study, maintains stable environmental parameters to create an ideal environment for cultivating tomato plants. Actuators, receiving commands from a cloud application situated at the network’s edge, automatically regulate environmental conditions. Decision-making within this application is facilitated by a PID control algorithm, ensuring precision in control commands transmitted through the MQTT protocol and the NGSI-LD message format. The system transitioned from a single virtual machine in the public cloud to edge computing, specifically on a Raspberry Pi 3, to address latency concerns. In this study, we analyzed various delay aspects and network latency to better understand their significance in delays. This transition resulted in a significant reduction in communication latency and a reduction in total service delay, enhancing the system’s real-time responsiveness. The utilization of LoRa communication technology connects IoT devices to a gateway, typically located at the main farm building, addressing the challenge of limited Internet connectivity in remote greenhouse locations. Monitoring data are made accessible to end-users through a smartphone app, offering real-time insights into the greenhouse environment. Furthermore, end-users have the capability to modify system parameters manually and remotely when necessary. This approach not only provides a robust solution to climate-induced challenges but also enhances the efficiency and intelligence of agricultural practices. The transition to digitization poses a significant challenge for farmers. Our proposed system not only represents a step forward toward sustainable and precise agriculture but also serves as a practical demonstrator, providing farmers with a key tool during this crucial digital transition. The demonstrator enables farmers to optimize crop growth and resource management, concretely showcasing the benefits of smart and precise agriculture.

A 0.5–15 GHz reconfigurable IR-UWB receiver in 28 nm CMOS

A 0.5–15 GHz ultra-wideband (UWB) RF reconfigurable receiver in UMC 28 nm CMOS used for IR-UWB (impulse radio UWB) radar system is proposed in this paper. This receiver employs a 0.5–8 GHz path and an 8–15 GHz path to achieve the wide frequency band, and we proposed an RF channel select voltage-to-time converter (VTC) circuit. Two different low noise amplifiers (LNAs) are adopted in the two paths to obtain the high performance of noise figure (NF) and gain. The common drain stage and resistance negative feedback technology as well as the source degeneration inductive technology are introduced to achieve a high flat gain and fine input matching. The R-2R variable load network of a programable gain amplifier (PGA) gives it a nearly 24 dB dynamic range and approximately linear gain control. A 500MS/s time domain analog to digital converter (TD-ADC) with an equivalent sampling rate of 16GS/s is shared for the two paths which can realize the direct RF sampling. The input RF signal path selection is implemented by configuring the Band_sel signal. The receiver has reconfigurability of the RF front end and better power consumption and area. In the frequency of 0.5–8 GHz, the S11 is below −7.9 dB and the NF is smaller than 6 dB. In the frequency of 8–15 GHz, the S11 is below −8dB and the NF is smaller than 11 dB. The receiver dissipates 242.72mW with an area of 1.01 mm2

Creating authentic and effective practice scenarios for digital simulation-based conversation training

In this article, we describe and illustrate a five-step process model for designing practice scenarios for digital simulation-based conversation training, in which learners practice challenging conversations with a virtual character. To maximize the likelihood of a successful learning experience, it is important that these practice scenarios are perceived as authentic by learners, and that they are based on relevant theory and validated expertise from experienced professionals. Our process model describes the steps that developers can take to (1) uncover implicit expertise concerning professional conversations, (2) build a validated conversation model including feasible response options and (3) optimize the play experience so that learners feel sufficiently immersed and engaged while using the simulation-based training. The design process, which is cyclical in nature, is illustrated by means of a case study in which we developed a training for cross-cultural job interviews. Furthermore, we provide practical templates and examples of questions that can be asked to experts and learners during preliminary testing of the scenario. By doing so, we aim to make the process of designing training scenarios more transparent and duplicable, and help developers to avoid pitfalls and tackle conceptual and practical challenges that arise during the design process.

Influential factors in the adoption of clinical decision support systems in hospital settings: a systematic review and meta-synthesis of qualitative studies

PurposeAdoption of Clinical Decision Support Systems (CDSS) is a crucial step towards the digital transition of the healthcare sector. This review aims to determine and synthesise the influential factors in CDSS adoption in inpatient healthcare settings in order to grasp an understanding of the phenomenon and identify future research gaps.Design/methodology/approachA systematic literature search of five databases (Medline, EMBASE, PsycINFO, Web of Science and Scopus) was conducted between January 2010 and June 2023. The search strategy was a combination of the following keywords and their synonyms: clinical decision support, hospital or secondary care and influential factors. The quality of studies was evaluated against a 40-point rating scale.FindingsThirteen papers were systematically reviewed and synthesised and deductively classified into three main constructs of the Technology–Organisation–Environment theory. Scarcity of papers investigating CDSS adoption and its challenges, especially in developing countries, was evident.Practical implicationsThis study offers a summative account of challenges in the CDSS procurement process. Strategies to help adopters proactively address the challenges are: (1) Hospital leaders need a clear digital strategy aligned with stakeholders' consensus; (2) Developing modular IT solutions and conducting situational analysis to achieve IT goals; and (3) Government policies, accreditation standards and procurement guidelines play a crucial role in navigating the complex CDSS market.Originality/valueTo the best of the authors’ knowledge, this is the first review to address the adoption and procurement of CDSS. Previous literature only addressed challenges and facilitators within the implementation and post-implementation stages. This study focuses on the firm-level adoption phase of CDSS technology with a theory refining lens.

Design and implementation of a low-cost circuit for medium-speed flash analog to digital conversions

Despite the considerable advancements in analog-to-digital conversion (ADC) circuits, many papers neglect several crucial considerations: Firstly, it does not ensure that ADCs work well in the software or hardware. Secondly, it is not certain that ADCs have a wide range of amplitude responses for the input voltages to be convenient in many applications, especially in electronics, communications, computer vision, CubeSat circuits, and subsystems. Finally, many of these ADCs need to look at the suitability of the proposed circuit to the most extensive range of frequencies. In this paper, a design of a low-cost circuit is proposed for medium-speed flash ADCs. The proposed circuit is simulated based on a set of electronic components with specific values to achieve high stability operation for a wide range of frequencies and voltages, whether in software or hardware. This circuit is practically implemented and experimentally tested. The proposed design aims to achieve high efficiency in the sampling process over a range of amplitudes from 10 mV to 10 V. The proposed circuit operates at a bandwidth of frequencies from 0 Hz to greater than 10 kHz in the simulation and hardware implementation.

IJCM_232A: Identification of Kinematic Motifs in Crouch Gait of Children with Cerebral Palsy

Background: Crouch Gait is a fairly common pathological gait adaptation seen in children with Cerebral Palsy, characterized by inadequacy of plantar flexion, knee extension and hip extension in the stance phase of gait. From a kinetic perspective crouch gait severely impairs the ability to generate thrusting forces through the extensor muscles of stance extremity which is necessary for forward progression. Broader goal of this study was to develop and test a wearable robotic exoskeletal device for children with crouch gait, where a knee actuator provides extensor thrust. Artificial Intelligence (AI) models which control the torque output of the knee actuator, needed to be trained to activate, control, or organize the output. Objectives: Rhythmical/repetitive patterns, like the phases of normal gait, needed to be identified in crouch gait, which could be used to train AI models Methodology: A total of 30 children with cerebral palsy were screened of which 7 children aged between 7 and 14 years, who presented with classical crouch gait were recruited. Kinesiological data was collected through accelerometric and goniometric placed bilaterally on thigh, leg, and knee, as well as pressure sensors embedded on to bilateral insoles at the fore-foot and hind foot, while the children walked over a 5 meter course. All sensor data was relayed through an Arduino micro-controller unit for analog to digital conversion and stored on a laptop computer. All Accelerometer and goniometric data was plotted against time on MS Excel to identify specific patterns or motifs. Results: Key kinematic motifs could be identified in crouch gait, which bestowed semblance of rhythmicity, and cyclical pattern, which was difficult to identify under normal observation. Conclusion: Accelerometric, as well as goniometric data suggest the presence of inherent kinematic patterns in the same. These could be used for training AI models for robotic exoskeletal devices.

Multi-Channel Nonlinearity Mitigation Using Machine Learning Algorithms

This paper investigates multi-channel machine learning (ML) techniques in the presence of receiver nonlinearities and noise, and compares the results with the single-channel receiver architecture. It is known that the multi-channel architecture relaxes the sampling speed requirement of analog to digital conversion and provides significant robustness to clock jitter and front-end noise due to the bandwidth-splitting property inherent in these receivers. However, when a high-voltage swing signal is used in a wireline communication link, the received signal suffers from third-order harmonic distortions and inter-modulation products caused by the nonlinearity profile of the analog front-end (AFE). To this end, this paper proposes the channel decision passing (CDP) algorithm in combination with nonlinear feedback cancellation as a low-complexity candidate for nonlinearity mitigation and compares the performance of this solution with other well-known ML algorithms. Simulation results show significant improvement in a multi-channel receiver architecture equipped with nonlinear feedback cancellation and CDP in comparison with its single-channel counterpart under practical nonlinearity profiles and noise conditions.

IJCM_268A: Navigating Transformative Pathways for SDGs through Innovation, Integration, and Implementation-A review of literature

Background: This literature review examines some key articles addressing the theme “Transformations for achieving SDGs: Innovate, Integrate, Implement.” The articles provide insights into the concerns, strategies, and evaluation processes related to sustainable development goals (SDGs) with a focusing on India. Objective: The primary objectives of this literature review are to analyze the approaches highlighted in the selected articles and to identify common themes and deviations in the strategies proposed for achieving SDGs. Methodology: A systematic review of the selected 11 articles was conducted to fetch relevant information regarding innovations, integration approaches, and implementation strategies for achieving SDGs. Every article was scrutinized for key themes, methodologies, and their findings. The analysis considered multiple perspectives presented in the literature, including case studies, literature reviews, and working papers. Results: The literature review showed a multifaceted understanding of the challenges and opportunities associated with achieving SDGs. Ahmad Mohd Khalid, Seema Sharma & Amlendu Kumar Dubey (2020) emphasized the specific concerns of developing countries, providing a case study for India. Srivastava (2018) advocated for standardized evaluation processes, highlighting a case study focused on India’s progress. Rosário and Dias (2022) explored the impact of digital transition on sustainability through a detailed literature review. Additionally, insights from the Journal of Sustainability Science and Management and the working paper by Bajpai and Biberman (2020) discussed the integration of SDGs in the ICT sector. Conclusion: The findings suggests a variety in the pursuit of SDGs, with a diverse range of strategies and considerations. Innovations, integration efforts, and implementation methodologies vary across contexts and different sectors. The challenges discussed underscore the need for specific approaches, stressing the importance of standardized evaluation processes. Overall, the literature highlights the complexity of achieving SDGs, necessitating a comprehensive and adaptive framework that integrates innovative solutions, interdisciplinary collaboration, and effective implementation strategies.

An Enhanced Strong ARM Comparator Circuit for Analog to Digital Converter Architectures

Abstract: Technological innovations in the current century period have motivated professionals to make electronic gadgets smarter. These advancements are progressing at a brisk pace, facilitating faster changes and increase in computing power. Various technologies such as virtual reality, augmented reality, mobile internet, artificial intelligence, cloud computing, biometric devices, 3D printing machines, genomics, quantum computing, block-chain, industrial automation and robotics. In all these technologies, communications with nearby devices play a major role in its effective functioning. The demand for realizing a smart and better usage experience puts forth strict requirements on the design aspects of next-generation high speed low power CMOS receiver design. One of the major modules in the implementation of high speed low power CMOS receiver device is the analog to digital converter (ADC) architecture. In the process of conversion from analog to digital signals, Quantization and sampling operations are vital and are realized using comparator circuits. The comparator design has a significant role in the design of data converter architecture. Several comparator architectures exist, but StrongARM topology is discussed and implemented in this work due to its negligible static power dissipation and rail to rail output voltages. The proposed novel comparator architecture is designed and simulated in 180nm CMOS process using Cadence Virtuoso tool and operated at supply voltage of VDD=1.8V, a clock frequency of 50MHz

FOSTERING DEVELOPMENT AND COMMUNITY RESILIENCE: THE ROLE OF FOLK MEDIA AND LITERATURE IN THE DIGITAL AGE

Folk media and literature have immense potential to contribute to the development process in the current world, especially in preserving cultural values, education, and the power of people. This paper aims to expand and discuss the traditional forms of media and their relevance within the culture and modern society and their relevance in the contemporary world especially within the digital realm. Thus, as part of this research, the results of a literature review, surveys, interviews, and case studies are used to evaluate how these traditional forms of expression have become part of digital media for the enhancement of socio-economic development. The study used a survey of 200 respondents from different areas of Andhra Pradesh State in India plus interviews with various stakeholders from Srikakulam, Vizianagaram, Parvathipuram Manyam, Visakhapatnam, Alluri Sitaram Raju, and Anakapalli districts. The findings highlight the dual benefits of digital transformation: expanding the accessibility of folk media and literature, as well as promoting cultural continuity and emergency capacity in related communities. The research findings from the case studies of Andhra Pradesh concerning digital storytelling, online archiving, and social networking site trailblazers indicate the effective strategies of share-simple and community engagement on one side and cultural heritage on the other side. The findings of the study show that adversaries of folk media not only expand their audience but also facilitate cultural participation by the communities. This research therefore emphasizes the need for collective responsibility to ensure that all cultures are preserved and facilitated through the digital transition to avoid a technological divide.

Digital education community TV existence in post analog switch off

Background: Based on Law (UU) Number 11 of 2020 regarding Cipta Kerja or the Omnibus Law, broadcasting institutions should switch from terrestrial or analog broadcasts to digital broadcasting via Analog Switch Off (ASO), which provides opportunities for community TV to develop. UGTV is Indonesia’s first digital education community TV to broadcast cultural and education-based programs. Purpose: To analyze the existence of UGTV as the first digital education community TV in Indonesia. Methods: Researchers distributed questionnaires to 144 respondents in Depok and 115 in Bekasi to determine the most popular programs. Researchers then conducted interviews with UGTV staff and leaders and compared the quality of UGTV programs based on KPI standards. Results: Based on the research results, UGTV as Indonesia’s first digital educational community television has met all KPI standards by offering some programs such as Team Teaching and Info Kampus. The types of broadcast programs in the form of tourism and cultural programs are still in demand and influence the audience’s viewing interest. Based on qualitative analysis as a follow-up analysis, the public response in these three areas is currently low because people have many new media choices that can be accessed easily at lower costs. Conclusion: The public feels that television lacks “interesting” shows so the existence of UGTV and other community channels can become a choice for the audience. Implications: KPI and KPID must actively monitor and develop broadcast content by collaborating with community broadcasting institutions so that broadcast production can be more varied.

Patient perceptions of disease burden and treatment of myasthenia gravis based on sentiment analysis of digital conversations

Myasthenia gravis (MG) is a rare, autoimmune, antibody-mediated, neuromuscular disease. This study analyzed digital conversations about MG to explore unprovoked perspectives. Advanced search, data extraction, and artificial intelligence-powered algorithms were used to harvest, mine, and structure public domain digital conversations about MG from US Internet Protocol addresses (August 2021 to August 2022). Thematic analyses examined topics, mindsets, and sentiments/key drivers via natural language processing and text analytics. Findings were described by sex/gender and treatment experience with steroids or intravenous immunoglobulin (IVIg). The 13,234 conversations were extracted from message boards (51%), social media networks (22%), topical sites (21%), and blogs (6%). Sex/gender was confirmed as female in 5703 and male in 2781 conversations, and treatment experience was with steroids in 3255 and IVIg in 2106 conversations. Topics focused on diagnosis (29%), living with MG (28%), symptoms (24%), and treatment (19%). Within 3176 conversations about symptoms, eye problems (21%), facial muscle problems (18%), and fatigue (18%) were most commonly described. Negative sentiments about MG were expressed in 59% of conversations, with only 2% considered positive. Negative conversations were dominated by themes of impact on life (29%), misdiagnosis problems (27%), treatment issues (24%), and symptom severity (20%). Impact on life was a key driver of negativity in conversations by both men (27%) and women (34%), and treatment issues was a dominant theme in conversations by steroid-treated (29%) and IVIg-treated (31%) patients. Of 1382 conversations discussing treatment barriers, 36% focused on side effects, 33% on lack of efficacy, 21% on misdiagnosis, and 10% on cost/insurance. Side effects formed the main barrier in conversations by both steroid-treated and IVIg-treated patients. Capturing the patient voice via digital conversations reveals a high degree of concern related to burden of disease, misdiagnosis, and common MG treatments among those with MG, pointing to a need for treatment options that can improve quality of life.