BackgroundDigital technology has a two-sided impact whether it is used appropriately or not. It is crucial to promote the benefits of digital technology and reduce its harms by bolstering adolescents’ digital literacy. The appropriateness of the strategies parents use to manage their children’s digital lives plays a key role. This study aims to investigate the separate effects of family socio-demographic factors and varied dimensions of parental mediation on adolescents’ digital literacy separately and simultaneously to explore the appropriate parental mediation strategies even in the absence of favorable family status.MethodsA cross-sectional survey was utilized with a sample of 1894 Chinese adolescents in junior and senior high schools (mean age = 14.01, 48.94% female), using a set of exam questions to test children’s objective digital literacy online. Family socio-demographic factors (parental marital status, economic status, and parental education levels) and varied dimensions of parental mediation were included as predictors of digital literacy. Hierarchical regression analysis was used to estimate the relation between the variables.ResultsHigher parental education levels were positively associated with adolescents’ parental mediation and digital literacy while better family economic status and parental divorce were negatively associated. Among the dimensions of parental mediation, active mediation, restrictive mediation and supervision were significantly associated with adolescents’ digital literacy, but not for co-use. Active mediation and supervision showed significant positive associations with adolescents’ digital literacy, whereas, co-use showed a significant negative association when all parental mediation dimensions were integrated into the model, The significant association between restrictive mediation and digital literacy disappeared. Parental mediation has diluted the impact of family socio-demographic factors on adolescents’ digital literacy.ConclusionsEffective interventions are needed to promote parental active mediation and supervision to help adolescents develop digital literacy and navigate the digital world, especially for adolescents who do not have highly educated parents or whose parents are divorced.