In this study, a dynamic caustic experimental system is used to examine the damage distribution characteristics as well as the crack formation/propagation mechanism in polymethyl methacrylate (PMMA) caused by uncoupled eccentric shaped charge blasting under different decoupling coefficients and charge positions. Using PMMA as the experimental material, the damage variables around the hole are calculated by the digital image processing method. The stress wave propagation law under different charge positions is revealed. Furthermore, based on the fractal theory, the damage values of shaped and unshaped cracks are calculated. The results show that the range of the crushed zone and failure zone on the coupled side around the hole of eccentric uncoupled charge is larger than that on the uncoupled side, which can reduce the damage on the reserved side and break the excavation side more fully. Under the condition of eccentric uncoupled charging, the range of the crack zone and failure zone decreases with the increase in the decoupling coefficient. When the decoupling coefficient is 2, the smoothness of the main crack is the best, and the total and average lengths of the main crack are also maximum. The damage distribution caused by explosive crack conforms to the fractal law, and the fractal dimension can accurately represent the damage degree of PMMA after the explosion.