‘Frame blocking’ or ‘Framing’ is a technique that divides a time-sampled speech or audio signal into consecutive and equi-sized short-time frames, either overlapped or non-overlapped, for analysis. The framing hardware architectures (FHA) in the literature support framing speech or audio samples of specific word size with specific frame size and frame overlap size. However, speech and audio applications often require framing signal samples of varied word sizes with varied frame sizes and frame overlap sizes. Therefore, the existing FHAs must be redesigned appropriately to keep up with the variability in word size, frame size and frame overlap size, as demanded across multiple applications. Redesigning the existing FHAs for each specific application is laborious, prompting the need for a configurable intellectual property (IP) core. The existing FHAs are inappropriate for creating configurable IP cores as they lack adaptability to accommodate variability in frame size and frame overlap size. Therefore, to address these issues, a novel FHA, adaptable to accommodate the desired variability, is proposed. Furthermore, the proposed FHA is transformed into a field-programmable gate array-based soft, ready-to-use and configurable frame blocking IP core using the Xilinx® Vivado™ tool (San Jose, CA, USA). The resulting IP core is versatile, offering configurability for framing in numerous applications incorporating real-time digital speech and audio systems. This research article discusses the proposed FHA and frame blocking IP core in detail.