Differential Scanning Calorimetry Curves Research Articles

Elucidation of the effect of hybrid copper/selenium nanofiller on the optical, thermal, electrical, mechanical properties and antibacterial activity of polyvinyl alcohol/carboxymethyl cellulose blend

AbstractPolymer nanocomposite samples of a polyvinyl alcohol (PVA)/carboxymethyl cellulose (CMC) blend doped with copper nanoparticles and selenium nanoparticles (Cu NPs/Se NPs) were prepared by the casting method. X‐ray diffraction analysis (XRD) patterns showed an increase in the degree of amorphous nature of the host polymeric matrix with increasing content of Cu/Se nanoparticles. The addition of 1.60 wt.%, Cu/Se NPs narrowed the indirect optical energy gap value of the nanocomposite from 3.97 to 2.39 eV. In addition, the differential scanning calorimetry (DSC) curve of the pure blend displays the miscibility of the blend components, confirmed by the presence of a single glass transition. Transmission electron microscopy (TEM) micrographs showed that the average sizes of Cu and Se nanoparticles are about 11 and 41 nm, respectively. The maximum values of AC and DC conductivity were 6.76 × 10−6 S.cm−1 and 5.49 × 10−10 for a PVA/CMC film filled with 1.60 wt.% of Cu‐Se NPs. The mechanical properties of the PVA/CMC blend improved after adding the hybrid NPs. Moreover, the antibacterial activity of the prepared samples was increased due to the filling of Cu‐Se nanoparticles to the films. Therefore, these results indicate the multifunctionality of PVA/CMC/Cu‐Se nanocomposite samples for use in electrical energy storage, solid‐polymer electrolytes, and food packaging industry.

Physico-chemical study of nitrazepam and citric acid eutectic mixture

The thermal and structural properties of nitrazepam and citric acid have been studied alone and in the corresponding binary mixture, using differential scanning calorimetry (DSC), Fourier Transform Infrared spectroscopy (FTIR), and X-ray diffraction (XRD). The thermodynamic study of the binary mixture nitrazepam-citric acid was made by DSC analysis. The mixtures were obtained by mechanosynthesis. For the binary mixtures, an eutectic reaction was observed in all DSC curves at 396 K. The phase diagram and Tamman's plot suggest an eutectic composition at the ≈0.4 molar fraction of nitrazepam. XRD and FTIR have been used as complementary methods to demonstrate that the obtained compound is eutectic. The solubility tests have been performed on the eutectic composition and nitrazepam. The results showed that the parameter influencing the solubility of nitrazepam is the acidic character of the sample.

Effect of Olive Pomace Fiber on the Baking Properties of Wheat Flour and Flat Bread (Barbari Bread) Quality

The current study is aimed at fortifying Barbari bread with different levels ( T Co : 0, T 5 % : 5%, T 10 % : 10%, and T 15 % : 15) of olive pomace dietary fiber (ODF) and investigating the quality properties of enriched bread. The fiber of the defatted olive pomace powder was extracted by an enzymatic process as a green extraction method (α-amylase, protease, amyloglucosidase, and cellulase; incubation time: 4.5 h, 40°C). The effect of ODF addition on the thermal (based on differential scanning calorimetry (DSC)), rheological, physical, textural, and sensory properties of samples was investigated. The DSC curves of samples were a broad endothermic transition peak ( T onset ~ 43 °C and T peak = 123.58 − 125.74 °C). By increasing the ODF level, the water absorption rate of the dough increased while softening degree reduced. There was a negative significant correlation between baking loss and crumb moisture ( R > − 0.94 ) and aw ( R = − 0.769 ). By increasing ODF, sample porosity and specific volume decreased. There was a significant difference between hardness and springiness of T 15 % and T Co . Replacement of wheat flour with 10% ODF had no significant effect on the sensory parameters of Barbari bread.

Effect of Bi2O3 on the physical, structural and gamma ray shielding properties of phosphate glasses inside the ternary P2O5-SrO-Bi2O3 system

Strontium phosphate glasses containing bismuth oxide were prepared using conventional melt-quenching technique. X-ray diffraction and differential scanning calorimetry (DSC) analysis suggests that stable ternary glasses of composition 70 P2O5-(30-x)SrO-xBi2O3 can be obtained for x = 5–25 mol%. This study examines such physical properties as the density, molar volume (Vm), glass transition temperature (Tg), and structural properties in the interest of explaining the effect on these glasses of Bi-Sr substitution. An almost linear increase in the density when the concentration of bismuth increases between x = 5 and x = 10 mol% followed by monotonic decreasing is noted. However, the calculated molar volume (Vm) behaves in exactly the opposite way. DSC curves showed that the glass transition temperature (Tg) decreases by 555 °C down to 490 °C as the concentration of Bi2O3 increases, due to the increase in the number of bridging oxygens. Structural investigations performed using IR spectroscopy revealed that the structure of the phosphate network contains predominately meta-phosphate (Q2) units, with contributions from pyrophosphate (Q1) and orthophosphate (Q0). The infrared spectra also revealed depolymerization of the phosphate chains in the glass system, with increased Bi2O3 concentration and the formation of P–O–Bi bonds. The study of the gamma ray shielding parameters showed that the prepared glasses can be used for shielding radiation applications.

A method to estimate the temperature at which the physical properties of dried noodles change

A method is proposed to detect the temperature, Tphy, at which dried noodles change their physical state during heating. The method was applied to dried spaghetti and udon (a Japanese noodle made from all-purpose wheat flour), and tested at various moisture contents. For both spaghetti and udon, Tphy almost coincided with the glass transition temperature, Tg, of noodles as determined by differential scanning calorimetry (DSC) when their moisture contents were about 0.15 kg-H2O/kg-d.m. or more. However, at moisture content levels less than this, Tphy was considerably lower than Tg and almost matched the temperature at which the DSC curve began to change stepwise in the first heating for the samples with no pretreatment for eliminating the effect of thermal history. The Tphy corresponded with the temperature at which relaxation due to the secondary molecular ordering occurred in the glass state.

Recycling of granite waste and burnt coal cinder for the preparation of sintered permeable bricks

AbstractThe sintered permeable brick was prepared using granite waste and burnt coal cinder (BCC) as raw materials to ensure the utmost utilization of both solid wastes. The effect of various parameters, such as the proportion of raw materials, granite particle size and sintering temperatures on the properties of the permeable brick were studied, and the relevant sintering mechanism was clarified. The differential scanning calorimetry curves indicate that the mixture of granite waste and BCC begins to melt at a lower temperature, which is lower than the temperature for melting them alone, so the use of them to prepare sintered bricks will reduce energy consumption. The optimal conditions for the preparation of the permeable bricks were determined as the mass ratio of granite waste to BCC of 80: 20, sintering temperature of 1150–1175°C, and granite particle size of .9–1.25 mm. It was found that the permeability and the flexural strength of the samples can reach 3.41 × 10 −2 cm/s and 4.2 MPa, respectively, which both exceed the requirements specified in the national standard of China.

Physicochemical fundamentals of processing solutions of thermoplastic poly(ether urethane)s to obtain fibrous-porous polymer composite materials

Objectives. To study the structure and properties of solutions of thermoplastic poly(ether urethane)s (PEUs) to inform their potential use in the production of fibrous-porous polymer composite materials with a given structure and set of performance properties depending on the field of practical application.Methods. The composition of PEUs was studied by attenuated total reflection infrared (ATR-IR) spectroscopy using a program for correcting the spectra on an IR Fourier spectrophotometer, as well by differential scanning calorimetry (DSC) using a heat flow calorimeter. The viscosity of PEU solutions was determined on a rotational viscometer.Results. The chemical composition of PEUs and the nature of the formation of hydrogen bonds were studied. An analysis of the spectra demonstrates the almost complete identity of the PEUs synthesized from the same 4,4'-diphenylmethane diisocyanate. In the studied PEUs of the Vitur and Desmopan® brands, as well as Sanpren, pronounced absorption bands characteristic of urethane groups involved in the formation of hydrogen bonds are visible in the region from 1702 to 1730 cm−1. The temperature transitions and thermal stability of the investigated PEUs were determined by DSC. The influence of the ratio of rigid and flexible blocks, as well as the nature of hydrogen bonds on the melting temperatures of polymers, was shown. Analysis of the DSC curves demonstrated all the studied PEUs to have high melting points ranging from 159 to 215°C. From the studied temperature dependences of the structural viscosity of thermoplastic PEUs solutions, all solutions were established to have a minimum viscosity anomaly; the value of the logarithm of viscosity depends on the chemical composition and structure of the initial PEUs. It is shown that the viscosity anomaly of PEU solutions can be reduced with increasing temperature.Conclusions. A comparison of the chemical composition, structure, thermal and rheological characteristics of thermoplastic PEUs with PEU solutions widely used for the production of fibrous-porous materials and coatings of Sanpren LQ-E-6 and Vitur R 0112 grades demonstrates their practicability as production materials and coatings having a predetermined structure and a set of properties depending on the requirements and operating conditions of finished products.

Effect of CeO2 Content on Melting Performance and Microstructure of CaO-Al2O3-SiO2-MgO Refining Slag

CeO2 can be applied to refining slag to minimize the size of inclusions, speed up the deoxidization process, and adsorb Al2O3 inclusions. The impact through which CeO2 content affects slag’s melting efficiency is still uncertain. The thermal analyzer was used to measure the thermogravimetric analysis (TG) and differential scanning calorimetry (DSC) curves of the slag melting process. According to the study results, with the increase in CeO2 content, the melting temperature of slag decreased first and then increased. The slag’s melting point fell from 1364 °C to 1324 °C and then rose to 1503 °C. XRD and SEM were used to analyze the CaO-Al2O3-SiO2-MgO-CeO2 slag’s microstructure. The mineral-phase structure of CeO2-containing refining slag was primarily composed of Ca2SiO4 and 3CaO·Al2O3, MgO, SiO2, CaO·Al2O3, and Ca8Ce6Al6O26. The proportion of 3CaO·Al2O3, CaO·Al2O3, and Ca2SiO4 decreased as the rare-earth-oxide content increased, while the proportion of Ca8Ce6Al6O26 increased. FactSage was used to estimate the equilibrium-phase compositions of slags with various compositions, and a model for predicting melting points was carried out by a linear regression model. Results were obtained through the analysis of equilibrium-phase composition and crystal structure transformation. The main reasons for the melting point decrease were the change of degree of polymerization and the decrease in contents and complete melting temperature of high-melting-point Ca3Al2O6 and Ca2SiO4 compounds. The latter increase in melting point was due to the number of Ca8Ce6Al6O26 compounds and precipitation temperature increases and the complexity of the structural-network increases.

Comparison of critical storage parameters of the powders containing soy protein isolate and inulin, based on the concepts: Water activity and Temperature of glass transition

In this study water activity and glass transition concepts were used to evaluate stability of the two component powder systems containing inulin and soy protein isolate. Moisture adsorption isotherms of soy protein powder with 25, 50 and 75 g of inulin on 100 g powders additions at 25 °C were determined by static gravimetric method. The experimental data obtained were fitted to three mathematical models. All curves exhibit sigmoidal shape corresponding to type II isotherms. The monolayer moisture content for GAB (Guggenheim–Anderson–Boer) model obtained for powder systems varied between 0.0647 and 0.0739 g water/g dry solids. Thermal transitions of equilibrated powders were analyzed using differential scanning calorimetry and glass transition curves were plotted by Gordon–Taylor equation. The highest value of glass transition temperature of anhydrous solid was calculated for soy protein without inulin addition. In order to investigate optimum storage conditions diagrams including water activity, equilibrium moisture content and glass transition relationship were constructed by using Khalloufi–El-Maslouhi–Ratti equation. Critical moisture content values of the powders estimated based on both, water activity and glass transition concepts, were significant higher than corresponding them monolayer capacity values.

Characterization of Poly(vinylidene Fluoride) Nanofiber-Based Electrolyte and Its Application to Dye-Sensitized Solar Cell with Natural Dyes

The potential of dye-sensitized solar cells (DSSC) as an alternative to depleting fossil fuels has been investigated. To optimize performance and efficiency, the effectiveness of PVDF and PVDF nanofiber (NF) membrane-based electrolytes in suppressing solvent leakage and evaporation in liquid electrolyte systems was evaluated. SEM results for PVDF NF membranes showed the formation of a network with a three-dimensional structure with a diameter of 100–300 nm and an average thickness of 0.14 mm. The Infrared (IR) spectrum shows the electrolyte and polymer-PVDF interactions. Differential Scanning Calorimetry (DSC) curve shows the melting transition of PVDF NF 7.66% lower than PVDF. Efficiency and resistance of DSSC based on natural dyes as measured by multimeter and Electrochemical Impedance Spectroscopy (EIS) at a solar intensity of 100 mW/cm2 showed the highest efficiency of anthocyanin-based DSSC from telang (Clitoria ternatea L.) flower extract. Its use as a photosensitizer in an electrolyte system based on PVDF NF membranes resulted in an efficiency that was not significantly different from that of liquid electrolytes (1.69%).

Optimum processing conditions for the maximum crystallization rate of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)

The effect of thermal and shear histories on the crystallization rate of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) was studied. As with other crystalline polymers, the shear history greatly affected the crystallization rate when the shear rate was beyond a critical value, i.e., the inverse of the Rouse relaxation time. Even after the formation of extended chain crystals, spherulite texture was clearly discernable. It grew from certain points on the extended chain crystals. Consequently, a row of spherulites appeared along the flow direction. The resin temperature in the molten state was also significant. When the sample was heated to 170 °C, which is beyond the main melting peak in the differential scanning calorimetry curve, unmolten crystals did not affect the linear viscoelastic properties. They acted as effective nucleating agents for the rest of the polymer during cooling. Therefore, the shear history hardly affected the crystallization rate and the number of spherulites.

Dynamic Cyclic Fatigue and Differential Scanning Calorimetry Analysis of R-Motion

The aim of this study was to assess the dynamic cyclic fatigue resistance of an R-Motion file at simulated body temperature and document corresponding phase transformations compared to OneCurve and HyFlex EDM (HFEDM). R-Motion (25/.06), OneCurve (25/.06), and HFEDM (25/.06) files were selected and divided into 3 groups (n=9) according to the file type. Dynamic cyclic fatigue testing was done with a custom-made artificial stainless-steel canal that had a 90° angle of curvature and a 5-mm radius of curvature. Files were operated continuously at body temperature until fracture in the artificial canal. The time to fracture was calculated. Statistical analysis was performed, and significance was set at 5%. Phase transformation temperatures for 2 instruments of each group were analysed by differential scanning calorimetry (DSC) analysis. The highest mean time to fracture value was measured in the HFEDM group (277.84 ± 2.51), followed by the R-Motion group (115.09 ± 0.01), whilst the lowest value was found in the OneCurve group (44.28 ± 3.63). Post hoc pairwise comparisons were all statistically significant (P < .001). DSC heating curves show austinite start temperatures to be 33.94 °C and 43.32 °C and austinite finish temperatures to be 35.09 °C and 50 °C for R-Motion and HFEDM, respectively. DSC cooling curves show martensite start temperatures to be 27.54 °C and 44.52 °C and martensite finish temperatures to be 29.13 °C and 37.68 °C for R-Motion and HFEDM, respectively. DSC curves of OneCurve failed to demonstrate transformation temperatures within the tested heat range. Crystalline arrangement of Ni and Ti atoms within the NiTi alloys greatly affects the dynamic cyclic fatigue resistance of the file.

Moisture Transfer During its Evaporation from Sugar Solutions

In this work, studies were carried out on the water evaporation from concentrated solutions of such sugars as sucrose, fructose, glucose, galactose, to determine the evaporation mechanisms. Differential scanning calorimetry (DSC) method in the temperature range from –70° C to +200° C, as well as the combined thermogravimetric analysis with differential scanning calorimetry under isothermal conditions at temperatures of 30°, 45°, 60 °C were used. The analysis of the DSC curves of sucrose solutions at low temperatures shows that in sugar solutions with a concentration of 65 %, water does not produce melting peaks. Therefore, it can be considered bound in the first hydration shells of sucrose. Isothermal thermogravimetric measurements give close to linear dependences of mass loss on time, and their slope being determined by temperature. At higher concentrations of sucrose solutions DSC curves for disaccharides are shifted relative to the curves for monosaccharides. This may be due to the lower permeability of the film surface for water. The evaporation model based on the vacancy mechanism of water molecules movement in concentrated sugar solutions was proposed. According to this model, the region enriched with vacancies of water molecules gradually penetrates deep into the sample. In this case, the number of water molecules in each layer of the region sets at a certain level. The given model constructions are applicable to the initial stages of water evaporation from concentrated sugar solutions.

Mechanical, optical, and physicochemical properties of HPMC-based doxazosin mesylate orodispersible films

In this study, orodispersible films formed from hydroxypropyl methylcellulose (HPMC) E6 (2, 2.5, and 3%) and plasticizers ((glycerin (Gly), propylene glycol (PP), or polyethylene glycol (PEG)), containing doxazosin mesylate, were prepared by the solvent casting method and characterized. Design of experiments (DoE) was used as a statistical tool to facilitate the interpretation of the experimental data and allow the identification of optimal levels of factors for maximum formulation performance. Differential scanning calorimetry (DSC) curves and X-ray powder diffraction (XRPD) diffractograms showed doxazosin mesylate amorphization, probably due to complexation with the polymer (HPMC E6), and the glass transition temperature of the polymer was reduced by adding a plasticizer. Fourier transformed infrared (FTIR) spectroscopy results showed that the chemical structure of doxazosin mesylate was preserved when introduced into the polymer matrix, and the plasticizers, glycerin and PEG, affected the polymer matrix with high intensity. The addition of plasticizers increased the elongation at break and adhesiveness (Gly > PEG > PP), confirming the greater plasticizer effect of Gly observed in DSC and FTIR studies. Greater transparency was observed for the orodispersible films prepared using PP. The addition of citric acid as a pH modifier was fundamental for the release of doxazosin mesylate, and the desirability formulation had a release profile similar to that of the reference product.

CALORIMETRIC STUDY OF PHASE TRANSITION OF Cu8GeSe6 AND COMPARISON WITH OTHER ARGYRODITE FAMILY COMPOUNDS

This work is a continuation of our work on the thermodynamic study of synthetic analogues of the mineral argyrodite. In this work, a calorimetric study of the phase transition of the Cu8GeSe6 compound was carried out using the differential scanning calorimetry (DSC) method. Based on the data of DSC curves of samples of the studied compound with different masses, the temperature and enthalpy of the phase transition from the low-temperature orthorhombic modification to the high-temperature cubic modification were established. Using the Gibbs-Helmholtz equation, the entropy of the phase transition was also calculated and the comparative analysis of the obtained thermodynamic values of the studied compound with other argyrodite phases was carried out.

Fabrication of whey protein isolate/chitosan complexes and its protective effect on allicin

AbstractWhey protein isolate (WPI) and chitosan (CS) complexes were prepared by complex coacervation method. The effects of different WPI/CS ratios and pH values on the formation of complexes were investigated. And then the protective effect of the WPI/CS complexes on allicin was further analyzed. The turbidity, particle size and zeta potential data showed that optimum soluble complex coacervation occurred at pH 5.0 when the WPI/CS ratio was 4:1. Electrostatic interaction and hydrogen bonding were the main driving forces involved in the coacervation. Changes in differential scanning calorimetry (DSC) curves indicated that WPI/CS complexes exhibited higher thermal denaturation temperature than WPI. The retention ratio of encapsulated allicin was 71.4% after stored at 4°C for 14 weeks, which was increased by 51.6% as compared with that of free allicin. Due to the denaturation of protein, a high‐temperature (90°C) and long‐time (7 h) treatment would result in a decrease of stability for encapsulated allicin. Results of this study would be helpful for designing food particles, which can be used for encapsulation and protection of bioactive molecules under certain conditions.

Development of high-performance Low-V BCC alloy for hydrogen storage by suction casting

Developing technologies to store hydrogen efficiently, safely, and economically is essential to achieve the application of hydrogen, among which V-based body-centered cubic (BCC) alloys are a promising material with a high theoretical storage capacity, but, the high cost of V hinder their practical applications. In this work, a novel V alloy with only 5 at% V was developed by suction casting (SC) method, reaching a dehydriding capacity up to 2.9 wt% H. The microstructural control and de-/hydrogenation mechanism for the developed alloys were further investigated systemically. It showed that the low-V alloy prepared by traditional casting displayed Laves phase, and the practical capacity only reached 2 wt% H. Instead, when the suction casting was used in preparation, the developed alloy maintained the single BCC phase and yielded 3.6 wt% H practical capacity, already comparable with V-based alloys. In addition, for the low V SC alloy, after hydriding, the phase structure was transformed from BCC to face-center cubic (FCC), easy to be recovered back to the original BCC structure. The hydrogenation kinetic is controlled by the nucleation growth mechanism with low activation energy, and the enthalpy change △H, was further confirmed by the differential scanning calorimetry curves. This work provided a significant guide for designing a new-generation hydrogen storage alloys with low cost and excellent hydrogen storage performances.

Curing behavior and properties of ultra-high temperature resistant RTM bismaleimide resin

The properties of a RTM bismaleimide resin with low viscosity and ultra-high temperature resistance were systematically investigated, including its curing kinetics and rheological properties, and the thermal and mechanical properties of its cured resins. The thermal curing kinetics was investigated by differential scanning calorimetry (DSC) method with multiple heating rates. DSC curves display a cure regime in the temperature range of 150∼300°C and the exothermic peaks shift from 194°C to 231°C with heating rate. The apparent activation energy of curing reaction is calculated as 78.2 kJ/mol. The rheological properties were studied in terms of the changes of the non-isothermal and isothermal viscosity tested using a rotary viscometer. The test results show that the RTM resin has a wide molding temperature window from 90°C to 200°C and long molding time at 110°C for 275 min with a flow viscosity less than 1000 mPas. Dual-Arrhenius model was established to predict the viscosity characteristics at different constant temperatures, showing a good agreement with the experimental data. Four curing cycles were designed to obtain cured networks with different microstructures, and the thermal and mechanical properties of the cured resins suffered from various curing cycles were characterized by dynamic mechanical analysis (DMA) and universal material testing machine. The results exhibit that the cured product has a ultra-high glass transition temperature of 373.5°C and larger flexural strength of 145.4 MPa after post-curing at 250°C for 10 h.

Application of a biomimetic wellbore stabilizer with strong adhesion performance for hydrate reservoir exploitation

Natural gas hydrate (NGH) in marine is usually reserved in the pores or cracks of weakly cemented argillaceous siltstones. Moreover, the hydrates are susceptible to variations in temperature and pressure conditions when water-based drilling fluids (WBDFs) are drilled into hydrate reservoirs, leading to the hydrate in-situ decomposition and severe sand production. In this work, an inexpensive and facilely prepared biomimetic wellbore stabilizer with strong adsorption of multiple hydrogen bonds was prepared by fusing catechol-rich tannic acid (TA) and polyvinyl alcohol (PVA) with polyol hydroxyl adsorption function, referred to as TA-PVA complex (TA-PVA). TA-PVA was added to WBDFs to strengthen the NGH reservoir wellbore for ensuring the safety of drilling process in a wide temperature range (2-60℃). The microscopic characterization of TA-PVA and its cohesion mechanism with argillaceous siltstone was investigated by Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), scanning electron microscopy (SEM) and atomic force microscopy (AFM). The mechanical properties of skeleton of the artificial hydrate cores were evaluated by compressive strength test, with maximum compressive strength reaching 0.45 MPa. And the adhesion force of TA-PVA to the probe modified by silica microsphere (PSM) was further studied by AFM. Meanwhile, the adhesion forces between TA-PVA and cyclopentane hydrate particles were measured at 1.5℃. Adhesion test results demonstrate that TA-PVA can bond clay particles, quartz sand and hydrate particles together. In detail, the adhesion force between TA-PVA and PSM reaches more than 164.46 mN/m, the adhesion force between TA-PVA droplet and cyclopentane hydrate particle reaches 43.19 mN/m. The differential scanning calorimetry (DSC)curves demonstrate that TA-PVA releases no heat between 0 and 60 °C, indicating that TA-PVA has no impact on the decomposition of NGH, showing the potential to maintain the integrity of NGH reservoir.

Thermodynamic Sensitivity of Blood Plasma Components in Patients Afflicted with Skin, Breast and Pancreatic Forms of Cancer.

According to the World Health Organization's 2018 Global Cancer Survey, cancer is the second leading cause of death. From this survey, the third most common is breast cancer, the fifth is melanoma malignum and pancreatic adenocarcinoma ranks twentieth. Undoubtedly, the early diagnosis and monitoring of these tumors and related research is important for aspects of patient care. The aim of our present review was to explain an impressive methodology that is deemed suitable in reference to studying blood sample deviations in the case of solid tumors. Essentially, we compared the heat denaturation responses of blood plasma components through differential scanning calorimetry (DSC). In the control, between five and seven separable components can be detected, in which the primary component was albumin, while in the case of tumorous patients, the peaks of immunoglobulins were dominant. Moreover, the shape of the plasma DSC curves changed with a shift in the higher temperature ranges; thus, their pattern can be used as a suitable marker of direct immunological responses. The further development of the analysis of DSC curves raises the possibility of the early diagnosis of a potential tumor, the monitoring of diseases, or testing the efficacy of the therapy from a single drop of blood.