Diaminodiphenyl Sulphone Research Articles

Synthesis and characterisation of new sulphur-containing epoxy networks

The position of sulphur within a cured epoxy amine network and its impact upon the thermal, mechanical, chemical and physical properties has been investigated in this study. Sulphur-containing epoxy resins, diglycidyl thioether of bisphenol A (DGTEBA) and diglycidyl ether of dithio diphenyl (DGTED) have been synthesised, cured and characterised and then compared with the benchmark epoxy resin, diglycidyl ether of bisphenol A (DGEBA). DGTEBA has two sulphur atoms located terminally to the epoxide groups, whilst DGTED has a sulphur atom located centrally between two phenyl groups. Evaluation of the properties and cure mechanism using 4,4′-diamino diphenyl sulphone (4,4′-DDS) as the hardener showed that when the sulphur was terminally located, the glass transition temperature, cure conversion, thermal stability, yield strain and stress decrease substantially, whilst the rate of cure and methyl ethyl ketone (MEK) ingress was comparatively higher. Near-infrared spectroscopy revealed that a competing hydrogen abstraction reaction mechanism deactivated the epoxide ring to nucleophilic attack to produce a heterogeneous network and poorer properties. In contrast, the properties and network structure of the DGTED-cured network, which had sulphur placed centrally between the diphenyl groups were similar to DGEBA except that MEK fluid ingress was reduced. The DGTEBA epoxy was also cured with other amines of varying reactivity to reveal that the hydrogen abstraction mechanism was dependent upon the reactivity of the hardener. Less reactive hardeners were dominated by the hydrogen abstraction mechanism, whilst the more reactive amines displayed a step-growth mechanism more typically associated with epoxy amine cure.

Tensile Properties and Fracture Toughness of Three Rubber-Modified Epoxies

This paper investigates the tensile properties and fracture toughness of a liquid rubber-modified highly crosslinked epoxy cured using 4,4 diaminodiphenyl sulphone (DDS/LR). The results for DDS/LR epoxy in relation to rubber and matrix properties are also compared with those of rubber-modified lowly crosslinked epoxy systems, namely, liquid rubber-modified piperidine cured epoxy (Piperidine/LR) and core-shell-rubber modified piperidine cured epoxy (Piperidine/CSR). It was found that highly crosslinked DDS/LR epoxy has a higher tensile strength than that of either Piperidine/LR or Piperidine/CSR epoxy, while it shows only a moderate increase in the fracture toughness.

Synthesis, characterization, and dynamic DSC curing kinetics of novel epoxy resin of 2,4,6-tris(4-hydroxyphenyl)-1-3-5-triazine

2,4,6-Tris(4-hydroxyphenyl)-1,3,5-triazine was synthesized by cyclotrimerization of 4-cyanophenol using trifluromethanesulphonic acid as a catalyst at room temperature. 2,4,6-Tris(4-hydroxyphenyl)-1,3,5-triazine was epoxidized using alkali as a catalyst at 60 °C for 1 h. Epoxy resin was cured by DSC at multiple heating rates under nitrogen atmosphere by using 20 % of 4,4′-diamino diphenylsulphone, 4,4′-diaminodiphenylether, and 4,4′-diaminodiphenylcyclohexane as hardeners. Cured and uncured reins were also analyzed by TG analysis. Kinetic parameters were determined and discussed in light of nature of curing agents. Thermal decomposition behavior of the samples is also discussed in detail.

Solving the Problem of Building Models of Crosslinked Polymers: An Example Focussing on Validation of the Properties of Crosslinked Epoxy Resins

The construction of molecular models of crosslinked polymers is an area of some difficulty and considerable interest. We report here a new method of constructing these models and validate the method by modelling three epoxy systems based on the epoxy monomers bisphenol F diglycidyl ether (BFDGE) and triglycidyl-p-amino phenol (TGAP) with the curing agent diamino diphenyl sulphone (DDS). The main emphasis of the work concerns the improvement of the techniques for the molecular simulation of these epoxies and specific attention is paid towards model construction techniques, including automated model building and prediction of glass transition temperatures (Tg). Typical models comprise some 4200–4600 atoms (ca. 120–130 monomers). In a parallel empirical study, these systems have been cast, cured and analysed by dynamic mechanical thermal analysis (DMTA) to measure Tg. Results for the three epoxy systems yield good agreement with experimental Tg ranges of 200–220°C, 270–285°C and 285–290°C with corresponding simulated ranges of 210–230°C, 250–300°C, and 250–300°C respectively.

Determination of nitrite in meat products and water using dapsone with combined spot test/diffuse reflectance on filter paper

This paper describes a simple, portable and environmentally friendly procedure for the determination of nitrite by combined spot test/diffuse reflectance spectroscopy on filter-paper. The method is based on the diazotization reaction of dapsone (4,4'-diamino-diphenyl sulphone, DAP) and (naphthyl)ethylenediamine hydrochloride (NED) with nitrite in acidic medium, yielding a coloured compound on the surface of a filter paper. Experimental design methodologies were used to optimise the measurement conditions. The reflectometric measurements were carried out at 545 nm and the linear range obtained was 0.29-5.0 mg L(-1) of nitrite (R=0.997), with detection and quantification limits of 0.09 and 0.29 mg L(-1), respectively. The proposed method was applied successfully to the analysis of nitrite in meat products and well water samples.

Synthesis, Characterization, and Conducting Properties of Poly(thiourea azomethines)

Three new polyazomethines having phenylthiourea groups were synthesized through solution polycondensation of terephthalaldehyde with 4,4′-bis(thiourea)biphenyl ether, 4,4′-bis(thiourea)biphenylmethane, and 4,4′-bis(thiourea)biphenyl sulphone. For comparison purposes, simple polyazomethines were prepared by the polycondensation of terephthalaldehyde with 4,4′-diaminodiphenyl ether, 4,4′-diaminodiphenylmethane, and 4,4′-diaminodiphenyl sulphone. Poly(imine)s having phenylthiourea groups were characterized through IR and 1H-NMR spectroscopic methods and the thermal stability of the polymers were evaluated through TGA analysis. Conductivity of polyaniline synthesized in aqueous p-toluenesulfonic acid was found to be 3.83 Scm−1. The conductivity of the polymeric blends with polyaniline dopped with p-toluenesulfonic acid and HCl (20% by weight) were found to be in the range 0.16 × 10−3 − 5.7 × 10−3 Scm−1.

Synthesis and Characterization of Epoxy-Containing Schiff-Base and Phenylthiourea Groups for Improved Thermal Conductivity

Three new diglycidyl monomers bearing phenylthiourea and azomethine groups were synthesized using 4,4′-diaminodiphenyl ether, 4,4′-diaminodiphenylmethane, and 4,4′-diaminodiphenyl sulphone as starting materials. The monomers were characterized through IR and 1H-NMR spectroscopic analysis. The monomers were blended with epoxy based trickle impregnation resin (Dobeckot 605) and cured. The cured resins were subjected to TGA and DSC analysis. Presence of 3% by weight of the diglycidyl monomers bearing thiourea and azomethine groups in the cured blends did not alter the thermal stability but increased the thermal conductivity. The thermal conductivity of the cured blends were approximately 1.9 times higher than that of epoxy-based trickle impregnation resin and comparable with the epoxy-based resin filled with 20% inorganic fillers.

Dapsone hypersensitivity syndrome complicated by Scedosporium apiospermum pneumonia in an immunocompetent patient

Dapsone (4,40diaminodiphenyl sulphone) has been used since the middle of the 20th century for leprosy treatment, usually in combination with rifampin and clofazimine. Dapsone hypersensitivity syndrome (DHS) occurs in 0.5-3% of patients treated with this drug. The exact immune mechanism behind this idiosyncratic reaction with multi-organ involvement is unclear. Some genetic and environmental factors, by increasing the production of dapsone-reactive metabolites or affecting the ability of the liver to detoxificate them, may increase the risk of developing DHS. Latency before the onset of symptoms can vary from 2-6 h, in previously sensitised patients, to 6 months [1]. Typical DHS manifestations include high fever, skin rash, malaise, methemoglobinaemia, liver toxicity (jaundice, hepatitis and hepatomegaly) and generalised lymphadenopathy. Acute renal failure, hypersensitivity pneumonia, cholangitis, sensory peripheral neuropathy, pancreatitis and pleural effusion have been reported less frequently [2]. The discontinuation of dapsone and the early initiation of high-dosage systemic corticosteroid therapy are crucial to decrease mortality and morbidity. Scedosporium spp. are hyaline filamentous fungi ubiquitously present in soil, sewage and polluted waters. Although these fungi have a uniform worldwide distribution, they are more commonly found in temperate climates than in tropical climates. The most common species responsible for human disease are Scedosporium apiospermum (teleomorph: Pseudallescheria boydii) and Scedosporium prolificans, both of which are very similar to Aspergillus spp. These pathogens, once mainly known as agents of cutaneous and subcutaneous tissue infections (e.g. maduromycosis) in immunocompetent patients, have recently been reported to cause systemic life-threatening infections in immunocompromised hosts with increasing frequency. Scedosporium-related pneumonia, meningoencephalitis, brain abscesses and endocarditis have been documented in patients with advanced human immunodeficiency virus (HIV) infection and haematological malignancies, as well as in stem cell transplantation recipients. In the international medical literature, there are only a few reports of life-threatening Scedosporium spp. infections in immunocompetent patients. Rodriguez-Tudela et al. [3], in a recent review of 162 cases of scedosporiosis, reported 34 infections in patients with no underlying chronic condition; of note, 23 of these cases (82%) had suffered surgery or traumatism before the acquisition of the infection. Katragkou et al. [4] reviewed 23 cases of Scedosporium apiospermum infection after near-drowning. In this particular condition, Scedosporium apiospermum has been reported to cause severe invasive infections, with frequent central nervous system dissemination, in young and immunocompetent hosts. We report the case of a patient who died of a rapidly progressive pneumonia caused by Scedosporium apiospermum. The patient we describe did not present any typical risk factor for this opportunistic infection, except for a 10-day course of steroid therapy administered to control a DHS. A 53-year-old Indian man presented with a 10-day history of fever, generalised itchy maculopapular rash involving the palms and soles, and jaundice. His past medical history was unremarkable, and he denied taking any medication on a regular basis. He had been living in Italy for the past 26 years, but he had travelled to his L. Ceccarelli G. Calisti (&) D. Delle Rose A. Ricciardi G. Maffongelli P. Sordillo L. Sarmati M. Andreoni Infectious Diseases Unit, Tor Vergata University Hospital, Viale Oxford 81, 00133 Rome, Italy e-mail: giorgiocalisti@gmail.com

Isothermal and non-isothermal cure of a tri-functional epoxy resin (TGAP): A stochastic TMDSC study

The isothermal cure of a highly reactive tri-functional epoxy resin, tri-glycidyl para-amino phenol (TGAP), with diamino diphenyl sulphone (DDS), at two different cure temperatures T c has been studied by both conventional differential scanning calorimetry (DSC) and by a stochastic temperature modulated DSC technique, TOPEM. From a series of isothermal cure experiments for increasing cure times, the glass transition temperature T g as a function of isothermal cure time is determined by conventional DSC from a second (non-isothermal) scan, and the vitrification time t v is obtained as the time at which T g = T c. In parallel, TOPEM experiments at the same T c lead directly to the determination of t v from the sigmoidal change in the quasi-static heat capacity. It is not possible to identify the glass transition temperature of the fully cured system, T g∞, in a third scan by conventional DSC. In contrast, with TOPEM a second (non-isothermal) scan at 2 K/min after the isothermal cure gives rise to three separate transitions: devitrification of the partially cured and vitrified material; almost immediate vitrification as the T g of the system again rises; finally another devitrification, at a temperature approximating closely to T g∞. Thus with TOPEM it is possible to obtain a calorimetric measure of the glass transition temperature of this fully cured system.

The Effect of CTBN Concentrations on the Kinetic Parameters of Decomposition of Blends of Epoxy Resins Modified with Carboxyl-Terminated Liquid Copolymer

Diglycidyl ether of bisphenol—A (DGEBA)—based epoxy resin was blended in the ratio of 3:1 (weight basis) with cycloaliphatic epoxy (CAE) resin. The prepared blend sample was further blended with different weight percentages of carboxyl-terminated butadiene acrylonitrile copolymer (CTBN) ranging between 0 and 25 wt% with an interval of 5 wt% and cured with stiochiometric amounts of 4, 4’- diamino diphenyl sulphone (DDS) cure agent. Structural changes during blending were studied by Fourier-transform infra-red (FTIR) spectroscopic analysis. The kinetic parameters, viz., order of decomposition reaction (n), activation energy (E), pre-exponential factor (Z) and rate decomposition constant (k), for the decomposition of the samples were calculated by applying Coats-Redfern equation over thermogravimetric (TG) data. The degradation of each sample followed second-order degradation kinetics, which was calculated by Coats-Redfern equation using best-fit analysis. This was further confirmed by linear regression analysis. The validity of data was checked by t-test statistical analysis. Further, the blend sample had higher initial degradation temperature and activation energy than its respective pure epoxy resin indicating that the CTBN acted as thermal stabilizer for epoxy resin which improved the thermal stability.

An Investigation into the Haematological Toxicity of Structural Analogues of Dapsone In-vivo and In-vitro

With microsomes prepared from a single human liver, 4,4'-diaminodiphenyl sulphone (DDS), 4-acetyl-4-aminodiphenyl sulphone (MADDS), 4-acetyl-4-aminodiphenyl thioether (MADDT) and 4,4'-diacetyldiphenyl thioether (DADDT) caused significantly greater methaemoglobin formation compared with control. In-vitro in the rat, the pattern of toxicity was slightly different:DADDT was not haemotoxic, whilst 3,4'-diaminodiphenyl sulphone (3,4'DDS) and 3,3'-diaminodiphenyl sulphone (3,3'DDS) as well as DDS, MADDS and MADDT were significantly greater than control. 4,4' Acetyl diphenyl sulphone (DADDS), 4,4' diaminodiphenyl thioether (DDT), 4,4'-diaminodiphenyl ether (DDE) and 4,4' diaminooctofluorodiphenyl sulphone (F8DDS) did not cause significant methaemoglobinaemia in either human or rat liver microsomes. DDS, MADDS, and MADDT were not significantly different in haemotoxicity generation in-vitro in the presence of human microsomes. In the rat in-vitro, DDS, MADDS, and 3,4'DDS did not differ significantly in red cell toxicity, and were the most potent methaemoglobin formers. The 3,3'DDS and MADDT derivatives were both significantly less toxic compared with DDS. None of the compounds tested caused haemoglobin oxidation in the absence of NADPH in-vitro. In the whole rat, DDS, MADDS and MADDT caused significantly higher levels of methaemoglobin compared with control. None of the remaining compounds caused methaemoglobin formation which was significantly greater than control. DDS and MADDS were the most potent methaemoglobin formers tested, in-vivo and in-vitro.(ABSTRACT TRUNCATED AT 250 WORDS)

Preparation, characterization, thermo‐mechanical, and barrier properties of exfoliated thermoplastic toughened epoxy clay ternary nanocomposites

AbstractTernary nanocomposites are prepared by blending hydroxyl‐terminated poly ether ether ketone having pendant methyl groups (PEEKMOH) with epoxy resin along with Nanolin DK1, followed by curing with 4,4′‐diamino diphenyl sulphone. Differential scanning calorimetry shows a two‐stage cure behavior indicating the catalytic effect of the primary amine and proton, which are generated by the dissociation of organic modifier. Tensile and flexural moduli are increased while tensile strength and glass transition temperature are decreased with increase in clay concentration. Fracture toughness and strain at break are increased by 59 and 62%, respectively, with 1 phr clay loading. Transition electron microscopy and X‐ray diffraction (XRD) analysis reveal exfoliated morphology for the nanocomposites. Scanning electron micrographs show a decrease in both, domain size as well as inter domain distance of the thermoplastic phase with the addition of clay, indicating the occurrence of gelation before phase separation. Analysis of the fracture surface reveals crack path deflection and ductile fracture behavior, confirming that toughness has been improved with the addition of clay and PEEKMOH. Coefficient of thermal expansion (CTE) of the nanocomposites is decreased up to 3 phr clay loading. Oxygen gas permeability is compared with Bharadwaj's and Neilson's models. A marginal improvement in thermal stability is observed with the addition of clay. Copyright © 2009 John Wiley & Sons, Ltd.

Comparison of the thermal properties between composites reinforced by raw and amino-functionalized carbon materials

Carbon materials, such as graphite oxides, carbon nanotubes and graphenes, have exceptional thermal conductivity, which render them excellent candidates as fillers in advanced thermal interface materials for high density electronics. In this paper, these carbon materials were functionalized with 4,4′-diaminodiphenyl sulphone (DDS), to enhance the bonding between the carbon materials and the resin matrix. Their visibly different properties were investigated. It seems that DDS-functionalization can obviously improve the interfacial heat transfer between the carbon materials and the epoxy matrix. The thermal conductivity enhancement of D-Graphene composites (0.493 W/m K) was about 30% higher than that of D-MWNTs composites (0.387 W/m K) at 0.5 vol.% loading. The different effects among EGO, D-EGO, MWNTs, D-MWNTs and D-Graphene in polymer composites were also discussed. It was demonstrated that DDS-functionalized carbon materials had an obvious effect on the thermal performances of composite materials and were more effective in thermal conductivity enhancement.

Influence of phenoxy modifier on mechanical, electrical and morphological properties of epoxy/DDS system

The blends of diglycidyl ether of bisphenol-A (DGEBA) and poly (hydroxyl ether of bisphenol-A) or phenoxy were synthesized by melt blending at 120 °C. These blends were cured by an aromatic amine hardener, 4,4′- diaminodiphenyl sulphone (DDS). The experiments were performed to study the different amount of phenoxy (10 to 40 parts per hundred resins) on mechanical and electrical properties of the DGEBA/phenoxy blends, such as tensile properties, flexural properties, impact strength, Rockwell hardness, and volume resistivity. The oxirane group of DGEBA epoxy resin reacts with hydroxyl group of phenoxy which provides good toughness to the epoxy resin. The tensile strength, tensile modulus, flexural strength, flexural modulus, heat deflection temperature and volume resistivity of DGEBA/phenoxy blends decreased with increasing the amount of phenoxy from 10 to 40 parts per hundred resins (phr). The opposite trend was observed in impact strength and Rockwell hardness of all DGEBA/phenoxy blends which were increased with increasing the phenoxy content from 10 to 20 phr, but then decreased upto 40 phr. The SEM studies revealed that the DGEBA/phenoxy blends show a multiphase system with an increase in the phenoxy content from 10 to 40 phr. due to inconvenience of mixing of two phases.

Synthesis of potential capacitive Poly 4, 4′-diaminodiphenyl sulphone–metal nanocomposites and their characterizations

4, 4′-Diaminodiphenyl sulphone was polymerized (with lithium/cobalt/lithium–cobalt salts) by chemical oxidation method using potassium perdisulphate. The solubility of the chemically prepared polymer–metal nanocomposite was ascertained and it showed good solubility in DMF, chloroform, trichloroethylene and DMSO. The PDDS–Li/Co/Li–Co nanocomposites were characterized by UV–vis and FTIR spectral studies. Amine and imine vibrations observed at 1593 and 1503 cm −1 were shifted to lower wave numbers when the polymer–metal composites were formed. A single absorption peak due to the N–H stretching vibration of the imino groups of polymer–metal nanocomposite is observed around 3459 cm −1 and it suggests the participation of NH group during polymerization. The X-ray diffraction studies revealed the formation of nano sized (82 nm) crystalline polymer. The conductivity of the PDDS–Li–Co nanocomposite was determined to be 6.26 × 10 −2 S cm −1. SEM analysis showed mixed granular nature of the polymer–metal nanocomposite. The capacitance (159.04 μF) of chemically synthesized PDDS–Li–Co nanocomposite is suggested as a potential capacitive material.

Preparation and characterisation of liquid crystalline epoxy/epoxy resin composites

A novel liquid crystalline epoxy resin, PHQEP, containing aromatic ester mesogen was synthesised from di(p-hydroxyl benzoic acid) hydroquinone (PHQ) and epichlorohydrin by phase transfer catalysis. The molecular structure of PHQEP was characterised by means of Fourier transformed infrared spectroscopy, hydrogen nuclear magnetic resonance spectroscopy, while its liquid crystalline phase behaviour was observed by a polarised optical microscope. The curing behaviour of PHQEP/diglycidylether of bisphenol A (E-51)/4,4′-diaminodiphenyl sulphone (DDS) system was studied by non-isothermal differential scanning calorimetry. Mechanical performance, thermal stability and dynamic mechanical property of PHQEP/E-51 composites were also investigated. The results revealed that PHQEP is a typical nematic liquid crystalline polymer. Impact strength of 5 wt-% PHQEP/E-51 was 2·6 times higher than that of E-51/DDS, and the initial decomposition temperature was 10°C higher than the value of E-51/DDS. The detailed reasons for the improvement of strength and thermal stability lie in the fact that origination of the mesogenic units of PHQEP was kept in the epoxy networks during the curing process.

Effects of a novel pyridylsulphonyl thiazole derivative, FR115092, on autoimmune and mitomycin C-induced thrombocytopenia in mice.

Dapsone (4,4'-diaminodiphenyl sulphone), an antileprotic and antimalarial drug, has been reported to be of therapeutic benefit in idiopathic thrombocytopenic purpura in the clinic. However, adverse reactions such as haemolytic anaemia have often been observed. In this study, we found that dapsone increased the number of platelets and decreased the number of red blood cells in male (NZWxBXSB)F1 (W/BF1) mice, an animal model of idiopathic thrombocytopenic purpura. In studies to prepare derivatives of dapsone with weaker side effects than the parent compound, FR115092 (2-[5-(2-pyridylsulphonyl)thiazolyl]amine) was discovered. The effect of FR115092 on the number of blood cells was studied and compared with dapsone in mice. FR 115092 increased the number of platelets without reducing the number of red blood cells in W/BF1 mice. This drug significantly suppressed the increase in circulating autoantibodies against platelets and increased the number of megakaryocytes. Furthermore, FR115092 inhibited the reduction of the number of platelets in mitomycin C-induced thrombocytopenic mice, as a consequence of its enhancement of growth and maturation of megakaryocytes. These findings suggest that FR115092 may be effective against various thrombocytopenias, without inducing haemolytic anaemia.

Spectroscopic, Mechanical and Dynamic‐Mechanical Studies on the Photo‐Aging of a Tetrafunctional Epoxy Resin

AbstractThe photo‐oxidative degradation of a densely cross‐linked epoxide/diamine network based on tetraglycidyl‐4,4′ diaminodiphenylmethane (TGDDM) and 4,4′ diaminodiphenyl sulphone (DDS) has been investigated by FTIR spectroscopy, dynamic‐mechanical analysis (DMA) and compressive mechanical tests. The FTIR measurements allowed us to monitor the degradation process of the different groups present in the TGDDM/DDS network and to obtain reliable kinetic data. On this basis the most likely photo‐degradation mechanisms were proposed. Dynamic‐mechanical measurements and mechanical compressive tests were used to gain an insight in the effect of the photo‐oxidative degradation on the relaxation processes of the epoxy network and on the mechanical performances.

DIGLYCIDYL BIPHENYLPHOSPHATE BASED FLAME RETARDANT LIQUID CRYSTALLINE THERMOSETS

Flame retardant liquid crystalline thermosets (FR‐LCTs) were synthesized from diglycidyl biphenylphosphate (DGBP), with various aromatic diamines namely, 2,5‐bis(p‐aminophenyl)‐1,3,4‐oxadiazole, 4,4′‐diaminodiphenyl sulphone, 4,4′‐ diaminodiphenyl methane, and biphenyldiamine. Cure kinetics and mesomorphic behavior of DGBP/diamine mixtures were performed on differential scanning calorimetry and hot stage optical microscope. Mechanical and cross‐linking properties of cured LCTs were characterized by dynamic mechanical analysis. The DGBP/diphenyldiamine combination exhibited high modulus and Tg values attributed to presence of more local order. The thermogravimetric analysis revealed that the LCTs were stable in the range 278–297°C with >43 Limiting Oxygen Index (LOI) values.

TTT Diagram Used to Control Phase Structure of 2/4 Functional Epoxy Blends for Advanced Composites

This article uses a 2/4 functional epoxy blend system (E-54/AG-80) cured with diaminodiphenyl sulphone(DDS) as a raw material and develops a methodological procedure to establish a cure kinetic model with isothermal and dynamic differential scanning calorimeter(DSC) method and a gelation model with round-disk compression mode dynamic mechanical analyzer(DMA), thus acquiring a series of experimental data. Characteristic temperatures such as initial glass transition temperature Tg0, gelation glass transition temperature gelTg, and infinite glass transition temperature Tg∞ are determined. The cure degree at gelation is turned out to be 0.45, while gelTg is found to be 70.2 °C. The data are then used to form time-temperature-transition(TTT) diagram of the system, which serves to be a tool for process optimization of epoxy-matrix composites. A new cure processing is therefore derived from the TTT diagram. The final phase structure obtained from a controllable method is identified through scanning electron microscope(SEM) photographs to be of ‘ex-situ’ phase morphology.