Screening Device Research Articles

A Longitudinal Study of CogEvo's Prediction of Cognitive Decline in Older Adults.

The predictive abilities of computer-based screening devices for early cognitive decline (CD) in older adults have rarely been longitudinally examined. Therefore, this study examined the ability of CogEvo, a short-duration, computer-based cognitive screening device requiring little professional involvement, to predict CD among community-dwelling older adults. We determined whether 119 individuals aged ≥ 65 years living in Japanese rural communities who scored ≥ 24 on the Mini-Mental State Examination (MMSE) at baseline developed CD by annually administering the MMSE to them. CD was defined as an MMSE score of ≤23. At baseline, the overall CogEvo judgment grade, with lower grades indicating better cognitive function, was calculated from the results of various cognitive tasks. Over 2 years, 10 participants developed CD. Participants with grades of 4 had a higher percentage of CD cases than those with grades of ≤3 (p < 0.01). This relationship remained significant after controlling for possible confounders, including the MMSE score at baseline. The sensitivity and specificity of the CogEvo grade cutoff of 4 were 50.0% and 93.6%, respectively. In conclusion, CogEvo may be an efficient tool for identifying individuals at a high risk for dementia. The possibility of missing CD cases should be considered when using CogEvo for screening.

The association between screen time exposure and myopia in children and adolescents: a meta-analysis

ObjectiveThis study aimed to systematically review epidemiological evidence on associations between screen time exposure and myopia in children and adolescents, and to quantitatively evaluate summary effect estimates from existing literature.MethodThere were three online databases including PubMed, Embase, and Web of Science, for epidemiological studies on screen time exposure and myopia published before June 1, 2023. The risk of bias was assessed by the Newcastle Ottawa Scale (NOS) checklist. Summary odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to evaluate the correlation between screen time exposure and myopia using random or fixed-effect models by exposure type (categorical/continuous). We also performed subgroup analysis by screen device type, study quality, geographic region, and research period.ResultsWe searched 7,571 records from three databases and identified 19 eligible studies, including 14 high-quality studies and 5 moderate-quality studies. Meta-analyses suggested that there was a statistically significant correlation between screen time (high vs. low) and myopia. The pooled ORs with 95%CIs were respectively 2.24 (1.47–3.42) for cross-sectional studies, and 2.39 (2.07–2.76) for cohort studies. We also found a significant association between continuous exposure to screen time (per 1 h/d increase) and myopia in cohort studies. The pooled ORs with 95%CIs were 1.07 (1.01–1.13). In subgroup analysis stratified by screen device type in cross-sectional studies, screen time exposures from computers (categorical: OR = 8.19, 95%CI: 4.78–14.04; continuous: OR = 1.22, 95%CI: 1.10–1.35) and televisions (categorical: OR = 1.46, 95%CI: 1.02–2.10) were associated with myopia, while smartphones were not. Although publication bias was detected, the pooled results did not show significant changes after adjustment using the trim and fill method.ConclusionOur findings support that screen time exposure was significantly associated with myopia in children and adolescents. Notably, screen time exposure from computers may have the most significant impact on myopia.

The relationship between parental attitudes and the assessment of the benefits and risks of screen devices use among children in early primary school years

Nowadays, children increasingly choose screen devices as a form of communication and spending free time, which raises concerns about the potential harmfulness of excessive use of them. Therefore, it seems important to look at the issue of using screen devices from the perspective of parents and their attitudes towards children themselves, as well as in relation to the use of screen devices in everyday life. The aim of the presented study was to demonstrate the relationship between parental attitudes, parent’s gender and the assessment of the benefits and risks associated with children’s screen devices use. The research tools used in the study included The Parental Attitudes Scale (SPR) by Mieczyslaw Plopa (2008), covering six parental attitudes, and original The Screen Usage Questionnaire (KKE) to measure the attitude towards screen use by children. The article discusses theoretical aspects of parental attitudes towards children and screen use, as well as the benefits and risks of children’s screen devices use in the early primary school years. The operationalization of variables in research tools was presented. The study involved 173 participants aged 29-44 years (M = 36.56; SD = 3.16; Me = 37), including 127 mothers and 47 fathers of children aged 7-10 from the Podkarpackie. No correlation was found between parental attitudes and their assessment of the benefits and risks associated with screen devices use. However, the differences were observed between mothers and fathers in the assessment of benefits and risks. The research results indicate the need for education on digital parenting. Mothers assessed the use of screens neutrally or negatively, while fathers assessed it neutrally or positively, hence the conclusion regarding preventive activities is to direct various educational interventions towards fathers and mothers. These findings indicate the need to support parents introducing children to the digital world in effective education regarding the use of screen devices.

Non-invasive hemoglobin screening device: a promising digital method for reducing anemia prevalence through routine screening and timely intervention

ABSTRACT Background Several non-invasive technologies are nowadays available in the market which claim to determine the hemoglobin levels instantly without the requirement of the blood sample. But no study has shown the significance of such non-invasive devices on a routine basis for determining their impact on anemia reduction programs. This study is conducted to determine the impact of regular hemoglobin screening on the women population to determine its potential in reducing anemia, using a digitalized non-invasive device. Method A cross-sectional study was conducted on 203 women of reproductive age group, residing in the Moradabad district. Repetitive readings were taken after a time interval of a minimum of 1 month for determining the impact of regular screening. The entire data collection process was carried out using the EzeCheck mobile app. Results It was observed that the prevalence of anemia was reduced upon the second time screening and was accepted by the women population. Repetitive testing has a significant impact on reducing anemia prevalence. Also, the simplified non-invasive technology for estimating the hemoglobin values, makes the user more comfortable to take the test. Conclusion Non-invasive devices should be used regularly to keep track of hemoglobin levels which will help in the effective treatment of anemia. The mobile app-based testing could help to easily evaluate the reports of the patients from any remote location with instant result interpretation and health assistance.

Efficient and Low-Loss Cleaning Method for Non-Uniform Distribution of Threshed Materials Based on Multi-Wing Curved Combination Air Screen in Computational Fluid Dynamics/Discrete Element Method Simulations

During the operation of the longitudinal axis flow threshing device of a combine harvester, the threshed materials form accumulations and blockages on both sides of the screen surface, severely affecting the harvesting process. To evenly distribute the materials on the screen and solve the blockage issue, a multi-wing curved combination centrifugal fan is designed to match the mass distribution of the threshed materials. The movement mechanism of rice threshed materials in the cleaning shoe of a longitudinal axis flow combine harvester is investigated using the coupled CFD-DEM simulation method. The cleaning efficiency and performance of the traditional straight-blade fan screen device and the newly designed cleaning device are compared and analyzed, and field tests are conducted. The results show that the trajectory of the threshed materials cleaned by the device equipped with the multi-wing curved combination centrifugal fan is consistent with the mass distribution of the materials separated by the longitudinal axis flow threshing device. The absolute value of the centroid velocity of the material group in the X/Y direction is greater than that of the traditional fan, indicating that the movement speed of the particle group in the optimized fan is greater than that of the traditional fan. Therefore, in the actual cleaning process, the optimized fan’s air flow distribution more effectively accelerates the movement speed of the threshed materials, increasing the amount of materials cleaned per unit time, thereby improving the cleaning efficiency. Field comparative tests show that the designed cleaning device reduced the cleaning loss rate by up to 25.00% and the impurity content rate by 32.20%, achieving efficient and low-damage cleaning of the combine harvester. The study demonstrates the effectiveness of the proposed method for evenly distributing the materials and provides important reference for the study of other piled particle distribution systems.

A quantum sensing metrology for magnetic memories

Magnetic random access memory (MRAM) is a leading emergent memory technology that is poised to replace current non-volatile memory technologies such as eFlash. However, controlling and improving distributions of device properties becomes a key enabler of new applications at this stage of technology development. Here, we introduce a non-contact metrology technique deploying scanning NV magnetometry (SNVM) to investigate MRAM performance at the individual bit level. We demonstrate magnetic reversal characterization in individual, <60 nm-sized bits, to extract key magnetic properties, thermal stability, and switching statistics, and thereby gauge bit-to-bit uniformity. We showcase the performance of our method by benchmarking two distinct bit etching processes immediately after pattern formation. In contrast to ensemble averaging methods such as perpendicular magneto-optical Kerr effect, we show that it is possible to identify out of distribution (tail-bits) bits that seem associated to the edges of the array, enabling failure analysis of tail bits. Our findings highlight the potential of nanoscale quantum sensing of MRAM devices for early-stage screening in the processing line, paving the way for future incorporation of this nanoscale characterization tool in the semiconductor industry.

The Utility of Expert-Rated and Self-Report Assessments of Youth Psychopathic Traits for Predicting Felony Recidivism Among Formerly Incarcerated Youth

Psychopathic traits assessed with expert-rated instruments are well-established predictors for both general and violent felony recidivism outcomes in adjudicated youth. However, it is not clear whether self-report assessments of psychopathic traits show similar predictive value. The current study evaluated both expert-rated (i.e., the Hare Psychopathy Checklist: Youth Version [PCL:YV]) and self-report measures (i.e., the Childhood Psychopathy Scale, Inventory of Callous Unemotional Traits, Antisocial Process Screening Device, and the Youth Psychopathic Traits Inventory) assessing youth psychopathic traits for predicting general and violent felony recidivism among formerly incarcerated high-risk male adolescents ( n = 275). Scores on both expert-rated and self-report instruments were significantly associated with a shorter time to felony rearrest into early adulthood (with an average follow-up window of 11 years). However, the expert-rated PCL:YV, but not self-report measures, provided significant utility for predicting violent felony arrest. These results suggest that in general, youth psychopathic traits, regardless of the specific instrument used, are predictors of general felony rearrest outcomes, while the expert-rated PCL:YV alone provides utility for predicting the most severe crimes (i.e., violent felonies). The strengths and limitations of the assessment modalities are discussed.

Using a Portable Ventilatory Airway Screening (PVAS) Device to Evaluate the Difference Between Upper Airway Breathing Pressure and Respiratory Flow in Skeletal Class I and Class II Growing Individuals With Retrognathic Mandible.

Background Upper airway obstruction (UAO) is a significant clinical concern due to its potential to lead to serious health issues, including obstructive sleep apnea (OSA) and cardiovascular diseases. Traditional diagnostic methods, such as spirometry, are often invasive and complex. This study aims to validate a portable ventilatory airway screening (PVAS) device as a non-invasive, cost-effective alternative for measuring upper airway breathing pressure and respiratory flow. Objectives To validate the accuracy of the PVAS device in measuring upper airway breathing pressure and respiratory flow by comparing its readings with those obtained from standard spirometry tests. Methods This cross-sectional analytical study involved 40 growing individuals aged 10-14 years, divided into two groups based on cephalometric analysis: Skeletal Class I (20 patients) and Skeletal Class II with retrognathic mandible (20 patients). Breathing pressure, volume, and velocity measurements were recorded using both the PVAS device and spirometry, and their accuracy was compared. Results The PVAS device showed high concordance with spirometry results, demonstrating significant accuracy in measuring breathing pressure, volume, and velocity. Skeletal Class II individuals exhibited significantly higher breathing pressure and reduced respiratory flow compared to Class I individuals, as measured by the PVAS device. Conclusion The PVAS device is a valid and accurate tool for non-invasive measurement of upper airway breathing pressure and respiratory flow. Its ease of use and reliability make it a valuable tool for clinical practice, particularly in the early diagnosis and management of airway obstructions.

Neonatal jaundice detection in low-resource Mexican settings: possibilities and barriers for innovation with mobile health

BackgroundNeonatal jaundice is a common condition that can lead to brain damage and disabilities when severe cases go undetected. Low- and middle-income countries often lack accurate methods for detecting neonatal jaundice and rely on visual assessment, resulting in a higher incidence of adverse consequences. Picterus Jaundice Pro (Picterus JP), an easy-to-use and affordable smartphone-based screening device for the condition, has demonstrated higher accuracy than visual assessment in Norwegian, Philippine and Mexican newborns. This study aimed to identify the barriers and facilitators to implementing Picterus JP in public health services in low-income settings in Mexico by exploring the current process of neonatal jaundice detection and stakeholders’ perspectives in that context.MethodsQualitative data collection techniques, including one focus group, 15 semi-structured interviews and four observations, were employed in urban and rural health facilities in Oaxaca, Mexico. The participants included medical doctors, nurses and health administrators. The data were analysed by thematic analysis guided by the Consolidated Framework for Implementation Research.ResultsThe analysis yielded four main themes: (I) the current state of neonatal care and NNJ detection, (II) the needs and desires for enhancing NNJ detection, (III) the barriers and facilitators to implementing Picterus JP in the health system and (IV) HCWs’ expectations of Picterus JP. The findings identify deficiencies in the current neonatal jaundice detection process and the participants’ desire for a more accurate method. Picterus JP was perceived as easy to use, useful and compatible with the work routine, but barriers to adoption were identified, including internet deficiencies and costs.ConclusionsThe introduction of Picterus JP as a supporting tool to screen for neonatal jaundice is promising but contextual barriers in the setting must be addressed for successful implementation. There is also an opportunity to optimise visual assessment to improve detection of neonatal jaundice.

Patient preference and acceptability of self-sampling for cervical screening in colposcopy clinic attenders: A cross-sectional semi-structured survey.

Low vaginal self-sampling has been pioneered as an important development to improve uptake of cervical screening globally. Limited research is available in specific patient groups in the UK exploring views around self-sampling to detect high-risk human papillomavirus (hrHPV) DNA. Therefore, we explored patient views to support development of a novel point-of-care self-sampling cervical cancer screening device, by undertaking a cross-sectional semi-structured questionnaire survey to explore preferences, acceptability, barriers and facilitators around self-sampling. Patients attending a colposcopy clinic, 25-64 years old, were invited to participate after having carried out a low vaginal self-sample using a regular flocked swab. Participants self-completed an anonymous 12-point questionnaire. Quantitative data were analysed in MS Excel and Graphpad Prism, and qualitative data with Nvivo. We recruited 274 patients with a questionnaire response rate of 76%. Acceptability of self-sampling was high (95%, n = 187/197; Cronbachs-α = 0.778). Participants were asked their choice of future screening method: a) low vaginal self-sampling, b) healthcare professional collected vaginal swab, c) cervical brush sample with healthcare professional speculum examination, or d) no preference. Preferences were: a) 37% (n = 74/198), b) 19% (n = 37/198); c) 9% (n = 17/198), and d) 35% (n = 70/198), showing no single option as a strong preference. Key motivators were: Test simplicity (90%, n = 170/190), speed (81%, n = 153/190) and less pain (65%, n = 123/190). Barriers included lack of confidence taking the sample (53%, n = 10/19), resulting in preference for a healthcare professional sample (47%, n = 9/19). Whilst self-sampling showed high acceptability, lack of strong preference for screening method may reflect that respondents attending colposcopy are already engaged with screening and have differing perception of cervical cancer risk. This group appear less likely to 'switch' to self-sampling, and it may be better targeted within primary and community care, focusing on under-screened populations. Any shift in this paradigm in the UK requires comprehensive education and support for patients and providers.

Inadequacy of a 12.5 cm MUAC as a cutoff for malnutrition for children aged three to five years

Introduction: MUAC (mid-upper arm circumference) is a simple and easily taught screening tool for identifying malnutrition in children. South Sudan use a MUAC of 12.5 cm for children aged between six months and five years as a cut-off for moderate acute malnutrition. Currently, in South Sudan, children from six months to five years have the same MUAC cutoff for malnutrition. Method: This study evaluated the sensitivity of using a MUAC of 12.5 cm as a screening tool for children between 6 and 60 months applied to data obtained from children enrolled in urban and rural primary schools in Maridi County, South Sudan. We used the 12.5 cm cutoff which was 2 standard deviations from the median for boys at nine months and for girls at 20 months. We also used 14.0 cm as the cutoff and compared the number of children identified, and also the false positive rate, assuming -2 SD from the median to be the accepted norm for malnutrition. Finally, we considered two different standards, using 14.0 cm for children aged 3-5 years and 12.5 cm for children under three years. Results: Comparing the results obtained using the two different MUAC standards (12.5 cm versus 14.0 cm) against a single MUAC standard there is a dramatic difference in outcome. Using the current standard (12.5 cm), only 7.3% of the children were found to be malnourished. Using 14.0 cm, 33.8 % were found to be malnourished (Table 4). If we accept the norm of 2 SD below the median for age as an adequate definition of malnutrition, the false positive rate using 14.0 cm is 9.6 %, an acceptable figure for a screening device, but the false negative rate for 12.5 cm is 17.4 %, a clearly unacceptable rate for a screening device. If, however, instead of using one cut-off for children from six months to five years, a period characterized normally by rapid growth and changes in body composition, we used two different standards—12.5 cm for those under three years and 14 cm for those aged 3-5 years, the number of false positives drops down to 2.7% and false negatives to 0.9 % Conclusion: We suggest that the use of 12.5 cm for malnourished children is inappropriate above two years, that 14 cm would be a more appropriate screening measurement from 3-5 years of age.

Accelerometer-measured sleep behaviour and parent-child sleep guideline adherence and sleep quality in Czech families with children aged 3-8 years: the FAMIly Physical Activity, Sedentary behaviour and Sleep (FAMIPASS) study.

Assessing parent-child relationship in sleep behaviours is important for facilitating changes in the sleep guideline compliance in preschool age children. The aim of this study was to examine accelerometer-measured sleep quantity and quality in families with children aged 3-8 years and investigate the parents' influence on the child's sleep. The data were obtained from the Czech cross-sectional FAMIly Physical Activity, Sedentary behaviour and Sleep (FAMIPASS) study, with a final sample of 374 families. Families were recruited through the enrolment of their children in kindergartens/primary schools between March 2022 and May 2023. The sleep time window and total sleep time were assessed using a wrist-worn ActiGraph accelerometer. Participants wore this device continuously for 24 h/day over a period of 7 consecutive days. Demographic data and potential correlates were obtained via questionnaires completed by parents. Statistical analyses were completed using logistic regression and independent-samples Mann-Whitney U test. In all, 65.5% of children (60% boys, 70.9% girls) and 58.3% of parents (52.4% fathers, 64.3% mothers) achieved the recommended sleep duration. Greater sleep quantity and duration in good-quality sleep were significantly higher in girls/mothers, compared to boys/fathers. Preschoolers were more likely to comply with sleep guidelines if their mother (but not father) met the sleep recommendation and their mothers did not have a higher education level. Adhering to sleep guidelines in children was also associated with children's female gender, absence of screen device in the bedroom, and being more active. Given the high concurrence in mother-child sleep quantity, it is important to promote healthy sleep behaviours in the whole family.

Analysis of unknown (unlabeled/mislabeled) drug products for active pharmaceutical ingredients and related substances by an international mail facility satellite laboratory equipped with rapid screening devices.

Two chemists employed a three-device rapid screening "toolkit" consisting of a handheld Raman spectrometer, transportable mass spectrometer, and portable Fourier transform infrared (FT-IR) spectrometer at an international mail facility (IMF) satellite laboratory to examine unknown (unlabeled/mislabeled) products for the presence of active pharmaceutical ingredients (APIs). Phase I of this project previously demonstrated that this toolkit was the most effective collection of instruments for identifying APIs in product types collected at IMFs during a nationwide mail blitz and Phase II of this project previously demonstrated that results generated using the toolkit during a satellite laboratory pilot program were as reliable as those generated by a full-service library when two or more of these instruments identify an API. This study (Phase III) described the results of the satellite laboratory toolkit during production mode and encompassed the period ranging from June 2021 through December 2022. During this study, a total of 858 products were examined on-site at the IMF. The satellite laboratory yielded conclusive results for 726 (84.6%) products, which were used to support regulatory action, and identified 132 (15.4%) products that required additional full-service laboratory analyses due to inconclusive results. The satellite and full-service laboratory verified/confirmed at least one API/related substance in 617 (71.9%) products. A total of 709 APIs/related substances were found in the 617 products, and 202 of these 709 compounds were unique/different. Overall, during Phases I through III of this program, 350 different substances have been identified in products collected at IMFs.

Devices for cervical cancer screening: a narrative review

This research aimed to describe the scientific and patent literature on devices for visual inspection of the cervix in cancer screening. The searches were performed without time restriction in the PUBMED, ScienceDirect and Scopus databases. For patent review, the technological bases named The Lens, Patentscope/WIPO[1], Espacenet, USPTO[2], and INPI[3] were used. Based on the strategy (“Cervix Uteri” AND Neoplasms AND “Equipment and Supplies” AND Patent), sixty-four articles were identified, of which 61 were excluded and 03 selected for analysis. Considering four combinations of the terms “Schiller”, “lugol”, “iodine”, “cervical cancer test”, “device”, “gynecological test”, “sponge”, “cervical”, “cervical test”, “Schiller’s test” and “diagnostic”, three hundred and sixty-three patents were returned, of which 22 dealt with devices. Of these, nineteen were duplicates and 03 were selected for analysis. Considering the 03 articles and 03 patents selected for analysis, only 03 met the study objective, being 01 granted patent and 02 scientific articles. However, none of them represents a tool for the practice of visual inspection of the cervix through Schiller's test and visual inspection with acetic acid. Thus, the study showed the need for the development of new technologies focused on the practice of visual inspection of the cervix and strengthening of cervical cancer screening.

SELF-IMAGE AND SELF-ESTEEM IN CHILDREN WITH DYSLEXIA

Children with dyslexia often face challenges beyond academic performance, which can lead to negative self-perceptions and reduced self-esteem. The association between self-image and self-esteem was assessed in the current study of sixty children with dyslexia (boys = 36, girls = 24). It was assumed that the self-image and self-esteem of children with dyslexia were directly associated with dyslexia. It was also hypothesized that children with dyslexia would have a negative self-image and low self-esteem. Children of 7-12 years (M = 9.7 SD = 1.66) were recruited from English medium schools of Faisalabad for the study. The Bangor Dyslexia Test was used as a quick screening device for finding out whether the subject’s difficulties were or were not typically dyslexic. Urdu version of Self Image Profile (Butler, 1998) was administered to children to find their self-image (positive and negative) and self-esteem (low and high). The results suggested that most children with dyslexia had a negative self-image and low self-esteem. Results depicted that 63 % of the sample had a negative self-image and 60 % of the sample had low self-esteem. Boys showed more negative self-image than girls; on the contrary, girls showed lower self-esteem than boys. It was concluded that children with dyslexia showed a negative self-image and low self-esteem. The findings of the current study might be helpful for the parents and the school teachers to get acquainted with the issue of dyslexia in the school population and its impact on their academic performance.

Screening and diagnosis of atrial fibrillation using wearable devices.

In recent years, the development and use of various devices for the screening of atrial fibrillation (AF) have significantly increased. Such devices include 12-lead electrocardiogram (ECG), photoplethysmography systems, and single-lead ECG and ECG patches. This review outlines several studies that have focused on the feasibility and efficacy of such devices for AF screening, and summarizes the risks and benefits involved in the initiation of anticoagulant therapy after early detection of AF. We also describe several ongoing trials on unresolved issues associated with AF screening. Overall, this review provides a comprehensive summary of the current state of AF screening and its implications for patient care.

Enhancing resource utilization: A novel method for effective separation of residual film and impurities in cotton fields

This study addresses the challenge of incomplete separation of mechanically recovered residual films and impurities in cotton fields, examining their impact on resource utilization and environmental pollution. It introduces an innovative screening method that combines pneumatic force and mechanical vibration for processing crushed film residue mixtures. A double-action screening device integrating pneumatic force and a key-type vibrating screen was developed. The working characteristics of this device were analyzed to explore the dynamic characteristics and kinematic laws of the materials using theoretical analysis methods. This led to the revelation of the screening laws of residual films and impurities. Screening tests were conducted using the Central Composite Design method, considering factors such as fan outlet, fan speed, vibration frequency of the screen, and feeding amount, with the impurity-rate-in-film (Q) and film-content-in-impurity (W) as evaluation indexes. The significant influence of each factor on the indexes was determined, regression models between the test factors and indexes were established, and the effect laws of key parameters and their significant interaction terms on the indexes were interpreted. The optimal combination of working parameters for the screening device was identified through multivariable optimization methods. Validation tests under this optimal parameters combination showed that the impurity-rate-in-film was 3.08% and the film-content-in-impurity was 1.94%, with average errors between the test values and the predicted values of 3.36% and 5.98%, respectively, demonstrating the effectiveness of the proposed method. This research provides a novel method and technical reference for achieving effective separation of residual film and impurities, thereby enhancing resource utilization.

Contraband Identification Algorithm for Intelligent Millimeter-wave Security Screening Device based on Regional-convolution Neural Network Algorithm for Civil Aviation

Contraband Identification Algorithm for Intelligent Millimeter-wave Security Screening Device based on Regional-convolution Neural Network Algorithm for Civil Aviation

청소년을 대상으로 한 반사회적 성격 평가 척도 APSD(Antisocial Process Screening Device) 타당화 연구 : 문항반응이론을 중심으로

청소년을 대상으로 한 반사회적 성격 평가 척도 APSD(Antisocial Process Screening Device) 타당화 연구 : 문항반응이론을 중심으로

A photoelectrochemical platform constructed with C-doped ZnIn2S4 /Bi2S3: Excellent for the visual detection of tumor marker

A photoelectrochemical (PEC) immunosensor based on a novel composite material was proposed for the highly sensitive and selective detection of Alpha-fetoprotein (AFP). C-doped ZnIn2S4/Bi2S3 (ZnIn2S4/Bi2S3/C) nanocomposites were synthesized in one pan by solvothermal method using glucose as carbon precursor and used as photoanode. ZnIn2S4/Bi2S3 displayed efficient visible light utilization and carrier separation efficiency. In addition, the high electrical conductivity of carbon materials also allowed ZnIn2S4/Bi2S3/C to show stronger photocurrent compared to ZnIn2S4/Bi2S3. The PEC sensor was successfully prepared in combination with a selective AFP antibody. The photocurrent decreased with the increase of AFP concentration in the range of 0.001–1000 ng mL−1, with a calculated detection limit of 0.12 ng mL−1. Besides, in order to eliminate the workstation's limitations, a colorimetric device that can display AFP levels nearly simultaneously was constructed by modifying Prussian blue on another FTO electrode and connecting the two electrodes by wires. This work provided a new approach for the instant detection of AFP in serum by developing a visualization device for rapid screening and identification of AFP by introducing the electrochromic principle and integrating the device from the viewpoint of improving the practicality of the sensing method.