The convincing potential of sophisticated milling tools exploited for machining of Inconel alloys in CNC milling machine offers minimal surface roughness-cutting force-cutting temperature trade-off footprint as compared to the conventional machining operation, which afforded a strong motivation to accomplish an in-depth discovery of the parametric design of CNC milling operation. In this study, the synergistic potential of contemporary Cubic boron nitride coated tool is used for machining of Inconel 690 in CNC milling machine, which has been scrutinized in order to build up a correlation among the objective function and the control variables by a metamodel called Adaptive Neuro-fuzzy inference system (ANFIS). The developed ANFIS model was capable of predicting the performance parameters with commendable accuracy as observed from correlation coefficients within the range of 0.946542–0.988996, Mean absolute percentage error (MAPE) in the range of 3.879652–7.456275% along with noticeably low root mean square errors (RMSE). Moreover, the ANFIS acquired results were compared with an Artificial Neural Network (ANN) model, developed on the identical parametric ranges. The comparison of the obtained results indicated that the ANFIS overtakes the ANN model in predicting the preferred response variables, which suggests the modesty of the ANFIS model.
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