In this article, a novel dynamic event-triggered protocol is constructed to deal with the filtering problem for affine systems presented by Takagi–Sugeno (T–S) fuzzy model. Unlike the traditional fuzzy systems, a unified framework of T–S fuzzy affine systems is formulated, which is more capable of approximation over different operating regions. For achieving desirable performance while saving communication resources, the memory-based dynamic event-triggered protocol is constructed by flexibly exploiting a series of historically triggered packets. The fading channel is time-varying and described as a novel nonhomogeneous Markov process, in which a higher level deterministic switching signal regulates the variation of transition probabilities. By adopting the region-dependent Lyapunov theory, the mean-square exponentially stable, and expected <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex-math notation="LaTeX">$H_{\infty }$</tex-math></inline-formula> performance for resulting systems is guaranteed. In the end, an inverted pendulum model is applied to verify the results of the theoretical analysis.