ABSTRACT Under the long-term influence of overburden load and water infiltration, coal undergoes creep damage, and the disturbance caused by mining activities can lead to sudden instability, triggering geological disasters such as mine flooding. Therefore, this study prepared four types of coal samples with different saturations under creep damage conditions and conventional coal samples. A comparative study was conducted using uniaxial compression tests to examine the deterioration characteristics of physical and mechanical parameters, failure modes, and energy evolution patterns in these two types of coal samples. Additionally, a microscopic deterioration model of coal samples under the combined influence of water and creep damage was constructed to elucidate the mechanism of creep damage on the deterioration of mechanical properties in water-containing coal samples. The research findings indicate that coal samples affected by creep damage and conventional coal samples exhibit significant consistency in mechanical parameters and energy evolution patterns. Specifically, an increase in saturation is positively correlated with peak stress, elastic modulus, and dissipated energy. Conversely, peak strain, total input energy, and elastic strain energy are negatively correlated with rising saturation levels. Under the same saturation conditions, the change in mechanical parameters and energy characteristics is more pronounced in creep-damaged coal samples. Furthermore, the stress-strain curves of both coal sample types exhibit prolonged compaction stages, shortened elastic stages, and more significant yield stages. Under equivalent saturation levels, the stress-strain trends in creep-damaged coal samples show more substantial variations. Upon loading and failure, the conventional coal sample transitions from single inclined plane shear failure to tension-shear mixed failure as the saturation increases. Conversely, the creep-damaged coal sample shifts from “X”-type conjugate shear failure and tension-shear mixed failure to tension failure, signifying a tendency toward more complex failure modes. In cases where the coal sample has a water saturation of 41%, the deterioration of its mechanical parameters is primarily attributed to creep damage. However, when the water saturation reaches 41–100%, water plays a dominant role in the deterioration of the coal sample’s mechanical parameters. After experiencing creep damage, the internal micro-cracks of the coal sample are extensively developed, which is also the primary factor contributing to the deterioration of the coal sample’s mechanical properties and an increased proportion of dissipated energy.