Steady-state Visual Evoked Potential Detection Research Articles

An SSVEP-based BCI with 112 targets using frequency spatial multiplexing

Objective. Brain–computer interface (BCI) systems with large directly accessible instruction sets are one of the difficulties in BCI research. Research to achieve high target resolution ( ⩾ 100) has not yet entered a rapid development stage, which contradicts the application requirements. Steady-state visual evoked potential (SSVEP) based BCIs have an advantage in terms of the number of targets, but the competitive mechanism between the target stimulus and its neighboring stimuli is a key challenge that prevents the target resolution from being improved significantly. Approach. In this paper, we reverse the competitive mechanism and propose a frequency spatial multiplexing method to produce more targets with limited frequencies. In the proposed paradigm, we replicated each flicker stimulus as a 2 × 2 matrix and arrange the matrices of all frequencies in a tiled fashion to form the interaction interface. With different arrangements, we designed and tested three example paradigms with different layouts. Further we designed a graph neural network that distinguishes between targets of the same frequency by recognizing the different electroencephalography (EEG) response distribution patterns evoked by each target and its neighboring targets. Main results. Extensive experiment studies employing eleven subjects have been performed to verify the validity of the proposed method. The average classification accuracies in the offline validation experiments for the three paradigms are 89.16%, 91.38%, and 87.90%, with information transfer rates (ITR) of 51.66, 53.96, and 50.55 bits/min, respectively. Significance. This study utilized the positional relationship between stimuli and did not circumvent the competing response problem. Therefore, other state-of-the-art methods focusing on enhancing the efficiency of SSVEP detection can be used as a basis for the present method to achieve very promising improvements.

Leveraging Transfer Superposition Theory for StableState Visual Evoked Potential Cross-Subject Frequency Recognition.

In steady-state visual evoked potential (SSVEP)based brain-computer interfaces (BCIs), various spatial filtering methods based on individual calibration data have been proposed to alleviate the interference of spontaneous activities in SSVEP signals for enhancing the SSVEP detection performance. However, the necessary calibration procedures take time, cause visual fatigue and reduce usability. For the calibration-free scenario, we propose a cross-subject frequency identification method based on transfer superimposed theory for SSVEP frequency decoding. First, a multi-channel signal decomposition model was constructed. Next, we used the cross least squares iterative method to create individual specific transfer spatial filters as well as source subject transfer superposition templates in the source subject. Then, we identified common knowledge among source subjects using a prototype spatial filter to make common transfer spatial filters and common impulse responses. Following, we reconstructed a global transfer superimposition template with SSVEP frequency characteristics. Finally, an ensemble cross-subject transfer learning method was proposed for SSVEP frequency recognition by combining the sourcesubject transfer mode, the global transfer mode, and the sinecosine reference template. Offline tests on two public datasets show that the proposed method significantly outperforms the FBCCA, TTCCA, and CSSFT methods. More importantly, the proposed method can be directly used in online SSVEP recognition without calibration. The proposed algorithm was robust, which is important for a practical BCI.

Convolutional Neural Network-Based Classification of Steady-State Visually Evoked Potentials with Limited Training Data

One approach employed in brain–computer interfaces (BCIs) involves the use of steady-state visual evoked potentials (SSVEPs). This article examines the capability of artificial intelligence, specifically convolutional neural networks (CNNs), to improve SSVEP detection in BCIs. Implementing CNNs for this task does not require specialized knowledge. The subsequent layers of the CNN extract valuable features and perform classification. Nevertheless, a significant number of training examples are typically required, which can pose challenges in the practical application of BCI. This article examines the possibility of using a CNN in combination with data augmentation to address the issue of a limited training dataset. The data augmentation method that we applied is based on the spectral analysis of the electroencephalographic signals (EEG). Initially, we constructed the spectral representation of the EEG signals. Subsequently, we generated new signals by applying random amplitude and phase variations, along with the addition of noise characterized by specific parameters. The method was tested on a set of real EEG signals containing SSVEPs, which were recorded during stimulation by light-emitting diodes (LEDs) at frequencies of 5, 6, 7, and 8 Hz. We compared the classification accuracy and information transfer rate (ITR) across various machine learning approaches using both real training data and data generated with our augmentation method. Our proposed augmentation method combined with a convolutional neural network achieved a high classification accuracy of 0.72. In contrast, the linear discriminant analysis (LDA) method resulted in an accuracy of 0.59, while the canonical correlation analysis (CCA) method yielded 0.57. Additionally, the proposed approach facilitates the training of CNNs to perform more effectively in the presence of various EEG artifacts.

Filter bank second-order underdamped stochastic resonance analysis for implementing a short-term high-speed SSVEP detection

ObjectiveThe progression of brain-computer interfaces (BCIs) has been propelled by breakthroughs in neuroscience, signal processing, and machine learning, marking it as a dynamic field of study over the past few decades. Nevertheless, the nonlinear and non-stationary characteristics of steady-state visual evoked potentials (SSVEPs), coupled with the incongruity between frequently employed linear techniques and nonlinear signal attributes, resulted in the subpar performance of mainstream non-training algorithms like canonical correlation analysis (CCA), multivariate synchronization index (MSI), and filter bank CCA (FBCCA) in short-term SSVEP detection. MethodsTo tackle this problem, the novel fusions of common filter bank analysis, CCA dimensionality reduction methods, USSR models, and MSI recognition models are used in SSVEP signal recognition. ResultsUnlike conventional linear techniques such as CCA, MSI, and FBCCA, the filter bank second-order underdamped stochastic resonance (FBUSSR) analysis demonstrates superior efficacy in the detection of short-term high-speed SSVEPs. ConclusionThis research enlists 32 subjects and uses a public dataset to assess the proposed approach, and the experimental outcomes indicate that the non-training method can attain greater recognition precision and stability. Furthermore, under the conditions of the newly proposed fusion method and light stimulation, the USSR model exhibits the most optimal enhancement effect. SignificanceThe findings of this study underscore the expansive potential for the application of BCI systems in the realm of neuroscience and signal processing.

A data expansion technique based on training and testing sample to boost the detection of SSVEPs for brain-computer interfaces

Objective. Currently, steady-state visual evoked potentials (SSVEPs)-based brain-computer interfaces (BCIs) have achieved the highest interaction accuracy and speed among all BCI paradigms. However, its decoding efficacy depends deeply on the number of training samples, and the system performance would have a dramatic drop when the training dataset decreased to a small size. To date, no study has been reported to incorporate the unsupervised learning information from testing trails into the construction of supervised classification model, which is a potential way to mitigate the overfitting effect of limited samples. Approach. This study proposed a novel method for SSVEPs detection, i.e. cyclic shift trials (CSTs), which could combine unsupervised learning information from test trials and supervised learning information from train trials. Furthermore, since SSVEPs are time-locked and phase-locked to the onset of specific flashes, CST could also expand training samples on the basis of its regularity and periodicity. In order to verify the effectiveness of CST, we designed an online SSVEP-BCI system, and tested this system combined CST with two common classification algorithms, i.e. extended canonical correlation analysis and ensemble task-related component analysis. Main results. CST could significantly enhance the signal to noise ratios of SSVEPs and improve the performance of systems especially for the condition of few training samples and short stimulus time. The online information transfer rate could reach up to 236.19 bits min−1 using 36 s calibration time of only one training sample for each category. Significance. The proposed CST method can take full advantages of supervised learning information from training samples and unsupervised learning information of testing samples. Furthermore, it is a data expansion technique, which can enhance the SSVEP characteristics and reduce dependence on sample size. Above all, CST is a promising method to improve the performance of SSVEP-based BCI without any additional experimental burden.

A hybrid BCI combining SSVEP and EOG and its application for continuous wheelchair control

Brain-computer interfaces (BCIs) have emerged as one of the most promising techniques for individuals with motor disabilities to control external devices directly without peripheral pathways. While the discrete control strategy is widely adopted in BCI systems, the continuous control strategy provides intuitive and fluent control of robotic devices. However, the steady-state visual evoked potential (SSVEP)-based BCI is still far from practical applications of continuous control. One of the existing challenges is the long erroneous transition time, i.e., the duration from when the subject switches towards a new target to when the BCI system recognizes this new target. Therefore, this study proposed a hybrid BCI combining SSVEP and electrooculography (EOG). First, the prior probability distribution of the intended target was obtained by the SSVEP detection method. Different from directly picking the one with the maximum probability as the conventional SSVEP-based BCI did, the captured saccade event in the EOG signal served as an additional event to optimize this probability distribution, and the target was then extrapolated and outputted. An offline experiment simulating the target switching process and an online experiment of virtual wheelchair control were designed and conducted. The proposed hybrid BCI significantly outperformed the conventional SSVEP-based BCI in both the offline experiment (continuous accuracy:64.99 ± 3.44 % vs. 55.76 ± 3.67 %, transition time: 1.19 ± 0.073 s vs. 1.65 ± 0.08 s) and the online wheelchair control experiment (success rate: 81.67 ± 5.75 % vs. 16.67 %± 3.76 %; collision times with the dynamic obstacle: 1.50 ± 0.50 vs. 8.25 ± 0.37; minimum distance to dynamic obstacle: 1.41 ± 0.13 m vs. 0.31 ± 0.08 m). The results revealed that by combining the SSVEP and EOG signals, the proposed hybrid BCI can significantly diminish the transition time in SSVEP-based BCI and achieve continuous, fluent control. The present study provides a novel framework for integrating the SSVEP and EOG, and promotes the potential applications of continuous brain-actuated robotic devices.

Robust Similarity Measurement Based on a Novel Time Filter for SSVEPs Detection.

The steady-state visual evoked potential (SSVEP)-based brain-computer interface (BCI) has received extensive attention in research for the less training time, excellent recognition performance, and high information translate rate. At present, most of the powerful SSVEPs detection methods are similarity measurements based on spatial filters and Pearson's correlation coefficient. Among them, the task-related component analysis (TRCA)-based method and its variant, the ensemble TRCA (eTRCA)-based method, are two methods with high performance and great potential. However, they have a defect, that is, they can only suppress certain kinds of noise, but not more general noises. To solve this problem, a novel time filter was designed by introducing the temporally local weighting into the objective function of the TRCA-based method and using the singular value decomposition. Based on this, the time filter and (e)TRCA-based similarity measurement methods were proposed, which can perform a robust similarity measure to enhance the detection ability of SSVEPs. A benchmark dataset recorded from 35 subjects was used to evaluate the proposed methods and compare them with the (e)TRCA-based methods. The results indicated that the proposed methods performed significantly better than the (e)TRCA-based methods. Therefore, it is believed that the proposed time filter and the similarity measurement methods have promising potential for SSVEPs detection.

Cross-Subject Transfer Learning for Boosting Recognition Performance in SSVEP-based BCIs.

Steady-state visual evoked potential (SSVEP)-based brain-computer interfaces (BCIs) have been substantially studied in recent years due to their fast communication rate and high signal-to-noise ratio. The transfer learning is typically utilized to improve the performance of SSVEP-based BCIs with auxiliary data from the source domain. This study proposed an inter-subject transfer learning method for enhancing SSVEP recognition performance through transferred templates and transferred spatial filters. In our method, the spatial filter was trained via multiple covariance maximization to extract SSVEP-related information. The relationships between the training trial, the individual template, and the artificially constructed reference are involved in the training process. The spatial filters are applied to the above templates to form two new transferred templates, and the transferred spatial filters are obtained accordingly via the least-square regression. The contribution scores of different source subjects can be calculated based on the distance between the source subject and the target subject. Finally, a four-dimensional feature vector is constructed for SSVEP detection. To demonstrate the effectiveness of the proposed method, a publicly available dataset and a self-collected dataset were employed for performance evaluation. The extensive experimental results validated the feasibility of the proposed method for improving SSVEP detection.

Cross-Subject Transfer Method Based on Domain Generalization for Facilitating Calibration of SSVEP-Based BCIs.

In steady-state visual evoked potential (SSVEP)-based brain-computer interfaces (BCIs), various spatial filtering methods based on individual calibration data have been proposed to alleviate the interference of spontaneous activities in SSVEP signals for enhancing the SSVEP detection performance. However, the time-consuming calibration session would increase the visual fatigue of subjects and reduce the usability of the BCI system. The key idea of this study is to propose a cross-subject transfer method based on domain generalization, which transfers the domain-invariant spatial filters and templates learned from source subjects to the target subject with no access to the EEG data from the target subject. The transferred spatial filters and templates are obtained by maximizing the intra- and inter-subject correlations using the SSVEP data corresponding to the target and its neighboring stimuli. For SSVEP detection of the target subject, four types of correlation coefficients are calculated to construct the feature vector. Experimental results estimated with three SSVEP datasets show that the proposed cross-subject transfer method improves the SSVEP detection performance compared to state-of-art methods. The satisfactory results demonstrate that the proposed method provides an effective transfer learning strategy requiring no tedious data collection process for new users, holding the potential of promoting practical applications of SSVEP-based BCI.

Bayesian-Based Classification Confidence Estimation for Enhancing SSVEP Detection

The brain-computer interface (BCI) enables paralyzed people to directly communicate with and operate peripheral equipment. The steady-state visual evoked potential (SSVEP)-based BCI system has been extensively investigated in recent years due to its fast communication rate and high signal-to-noise ratio. Many present SSVEP recognition methods determine the target class via finding the largest correlation coefficient. However, the classification performance usually degrades when the largest coefficient is not significantly different from the rest of the values. This study proposed a Bayesian-based classification confidence estimation method to enhance the target recognition performance of SSVEP-based BCI systems. In our method, the differences between the largest and the other values generated by a basic target identification method are used to define a feature vector during the training process. The Gaussian mixture model (GMM) is then employed to estimate the probability density functions of feature vectors for both correct and wrong classifications. Subsequently, the posterior probabilities of being an accurate and false classification are calculated via Bayesian inference in the test procedure. A classification confidence value (CCValue) is presented based on two posterior probabilities to estimate the classification confidence. Finally, the decision-making rule can determine whether the present classification result should be accepted or rejected. Extensive evaluation studies were performed on an open-access benchmark dataset and a self-collected dataset. The experimental results demonstrated the effectiveness and feasibility of the proposed method for improving the reliability of SSVEP-based BCI systems.

Efficient Low-Frequency SSVEP Detection with Wearable EEG Using Normalized Canonical Correlation Analysis.

Recent studies show that the integrity of core perceptual and cognitive functions may be tested in a short time with Steady-State Visual Evoked Potentials (SSVEP) with low stimulation frequencies, between 1 and 10 Hz. Wearable EEG systems provide unique opportunities to test these brain functions on diverse populations in out-of-the-lab conditions. However, they also pose significant challenges as the number of EEG channels is typically limited, and the recording conditions might induce high noise levels, particularly for low frequencies. Here we tested the performance of Normalized Canonical Correlation Analysis (NCCA), a frequency-normalized version of CCA, to quantify SSVEP from wearable EEG data with stimulation frequencies ranging from 1 to 10 Hz. We validated NCCA on data collected with an 8-channel wearable wireless EEG system based on BioWolf, a compact, ultra-light, ultra-low-power recording platform. The results show that NCCA correctly and rapidly detects SSVEP at the stimulation frequency within a few cycles of stimulation, even at the lowest frequency (4 s recordings are sufficient for a stimulation frequency of 1 Hz), outperforming a state-of-the-art normalized power spectral measure. Importantly, no preliminary artifact correction or channel selection was required. Potential applications of these results to research and clinical studies are discussed.

An Adaptive Task-Related Component Analysis Method for SSVEP Recognition.

Steady-State Visual Evoked Potential (SSVEP) recognition methods use a subject’s calibration data to differentiate between brain responses, hence, providing the SSVEP-based brain–computer interfaces (BCIs) with high performance. However, they require sufficient calibration EEG trials to achieve that. This study develops a new method to learn from limited calibration EEG trials, and it proposes and evaluates a novel adaptive data-driven spatial filtering approach for enhancing SSVEP detection. The spatial filter learned from each stimulus utilizes temporal information from the corresponding EEG trials. To introduce the temporal information into the overall procedure, a multitask learning approach, based on the Bayesian framework, is adopted. The performance of the proposed method was evaluated into two publicly available benchmark datasets, and the results demonstrated that our method outperformed competing methods by a significant margin.

Bidirectional Siamese correlation analysis method for enhancing the detection of SSVEPs

Objective. Steady-state visual evoked potential (SSVEP)-based brain–computer interfaces (BCIs) have attracted increasing attention due to their high information transfer rate. To improve the performance of SSVEP detection, we propose a bidirectional Siamese correlation analysis (bi-SiamCA) model. Approach. In this model, an long short-term memory-based Siamese architecture is designed to measure the similarity between the SSVEP signal and the template in each frequency and obtain the probability that the SSVEP signal belongs to each frequency. Additionally, a maximize agreement module with a designed contrastive loss is adopted in the Siamese architecture to increase the similarity between the SSVEP signal and the reference signal in the same frequency. Moreover, a two-way signal processing mechanism is built to effectively integrate complementary information from two temporal directions of the input signals. Our model uses raw SSVEPs as inputs and can be trained end-to-end. Main results. Experimental results on a 40-class dataset and a 12-class dataset indicate that bi-SiamCA can significantly improve the classification accuracy compared with the prominent traditional and deep learning methods, especially under short data lengths. Feature visualizations show that the similarity between the SSVEP signal and the reference signal in the same frequency gradually improved in our model. Conclusion. The proposed bi-SiamCA model enhances the performance of SSVEP detection and outperforms the compared methods. Significance. Due to its high decoding accuracy under short signals, our approach has great potential to implement a high-speed SSVEP-based BCI.

Driving Mode Selection through SSVEP-Based BCI and Energy Consumption Analysis.

Background: The brain–computer interface (BCI) is a highly cross-discipline technology and its successful application in various domains has received increasing attention. However, the BCI-enabled automobile industry is has been comparatively less investigated. In particular, there are currently no studies focusing on brain-controlled driving mode selection. Specifically, different driving modes indicate different driving styles which can be selected according to the road condition or the preference of individual drivers. Methods: In this paper, a steady-state visual-evoked potential (SSVEP)-based driving mode selection system is proposed. Upon this system, drivers can select the intended driving modes by only gazing at the corresponding SSVEP stimuli. A novel EEG processing algorithm named inter-trial distance minimization analysis (ITDMA) is proposed to enhance SSVEP detection. Both offline and real-time experiments were carried out to validate the effectiveness of the proposed system. Conclusion: The results show that a high selection accuracy of up to 92.3% can be realized, although this depends on the specific choice of flickering duration, the number of EEG channels, and the number of training signals. Additionally, energy consumption is investigated in terms of which the proposed brain-controlled system considerably differs from a traditional driving mode selection system, and the main reason is shown to be the existence of a detection error.

DSCNN: Dilated Shuffle CNN Model for SSVEP Signal Classification

The steady state visual evoked potential (SSVEP) based brain-computer interface (BCI) system has attracted a lot of attention. It is a great challenge to increase the classification accuracy of SSVEP, especially in fatigue state. In this paper, we propose a dilated shuffle convolutional neural network (DSCNN) model to realize EEG-based SSVEP signal classification. Firstly, we conduct experiments to obtain SSVEP recordings in normal and fatigue states. Then combining continuous wavelet transform (CWT) and DSCNN, we construct a framework for realizing the SSVEP detection. In DSCNN, the signals are processed by three parallel dilated convolution layers firstly, then we extract the characteristics of the signals through channel shuffle and group convolution, while reducing the computational load. For normal condition, we reach an average accuracy rate of 96.75%, and for the data under fatigue state, the average accuracy of this method increases to 77.52%. Through the comparison with the existing methods, the effectiveness and advance of our method are proved, and the effect of channel shuffle on signal extraction is also demonstrated by comparison.

Novel Hybrid Brain-Computer Interface for Virtual Reality Applications Using Steady-State Visual-Evoked Potential-Based Brain-Computer Interface and Electrooculogram-Based Eye Tracking for Increased Information Transfer Rate.

Brain–computer interfaces (BCIs) based on electroencephalogram (EEG) have recently attracted increasing attention in virtual reality (VR) applications as a promising tool for controlling virtual objects or generating commands in a “hands-free” manner. Video-oculography (VOG) has been frequently used as a tool to improve BCI performance by identifying the gaze location on the screen, however, current VOG devices are generally too expensive to be embedded in practical low-cost VR head-mounted display (HMD) systems. In this study, we proposed a novel calibration-free hybrid BCI system combining steady-state visual-evoked potential (SSVEP)-based BCI and electrooculogram (EOG)-based eye tracking to increase the information transfer rate (ITR) of a nine-target SSVEP-based BCI in VR environment. Experiments were repeated on three different frequency configurations of pattern-reversal checkerboard stimuli arranged in a 3 × 3 matrix. When a user was staring at one of the nine visual stimuli, the column containing the target stimulus was first identified based on the user’s horizontal eye movement direction (left, middle, or right) classified using horizontal EOG recorded from a pair of electrodes that can be readily incorporated with any existing VR-HMD systems. Note that the EOG can be recorded using the same amplifier for recording SSVEP, unlike the VOG system. Then, the target visual stimulus was identified among the three visual stimuli vertically arranged in the selected column using the extension of multivariate synchronization index (EMSI) algorithm, one of the widely used SSVEP detection algorithms. In our experiments with 20 participants wearing a commercial VR-HMD system, it was shown that both the accuracy and ITR of the proposed hybrid BCI were significantly increased compared to those of the traditional SSVEP-based BCI in VR environment.

Multi-Objective Optimization-Based High-Pass Spatial Filtering for SSVEP-Based Brain–Computer Interfaces

Many spatial filtering methods have been proposed to enhance the target identification performance for the steady-state visual evoked potential (SSVEP)-based brain–computer interface (BCI). The existing approaches tend to learn spatial filter parameters of a certain target using only the training data from the same stimulus, and they rarely consider the information from other stimuli or the volume conduction problem during the training process. In this article, we propose a novel multi-objective optimization-based high-pass spatial filtering method to improve the SSVEP detection accuracy and robustness. The filters are derived via maximizing the correlation between the training signal and the individual template from the same target whilst minimizing the correlation between the signal from other targets and the template. The optimization will also be subject to the constraint that the sum of filter elements is zero. The evaluation study on two self-collected SSVEP datasets (including 12 and four frequencies, respectively) shows that the proposed method outperformed the compared methods such as canonical correlation analysis (CCA), multiset CCA (MsetCCA), sum of squared correlations (SSCOR), and task-related component analysis (TRCA). The proposed method was also verified on a public 40-class SSVEP benchmark dataset recorded from 35 subjects. The experimental results have demonstrated the effectiveness of the proposed approach for enhancing the SSVEP detection performance.

Latency Aligning Task-Related Component Analysis Using Wave Propagation for Enhancing SSVEP-Based BCIs.

Due to the high robustness to artifacts, steady-state visual evoked potential (SSVEP) has been widely applied to construct high-speed brain-computer interfaces (BCIs). Thus far, many spatial filtering methods have been proposed to enhance the target identification performance for SSVEP-based BCIs, and task-related component analysis (TRCA) is among the most effective ones. In this paper, we further extend TRCA and propose a new method called Latency Aligning TRCA (LA-TRCA), which aligns visual latencies on channels to obtain accurate phase information from task-related signals. Based on the SSVEP wave propagation theory, SSVEP spreads from posterior occipital areas over the cortex with a fixed phase velocity. Via estimation of the phase velocity using phase shifts of channels, the visual latencies on different channels can be determined for inter-channel alignment. TRCA is then applied to aligned data epochs for target recognition. For the validation purpose, the classification performance comparison between the proposed LA-TRCA and TRCA-based expansions were performed on two different SSVEP datasets. The experimental results illustrated that the proposed LA-TRCA method outperformed the other TRCA-based expansions, which thus demonstrated the effectiveness of the proposed approach for enhancing the SSVEP detection performance.

Relation of canonical correlation analysis and multivariate synchronization index in SSVEP detection

Canonical correlation analysis (CCA) and multivariate synchronization index (MSI) are two most extensively signal processing algorithms to detect steady-state visual evoked potentials (SSVEP) in brain-computer interfaces (BCI). However, there is no standard principle to choose the proper algorithm in a practical system. Conventionally, algorithm selection is determined by experimental comparisons. A drawback of this method is that the corresponding reference significance reduces sharply as the experimental conditions are changed. In this paper, the conversion relationship between the above algorithms is verified through a rigorous mathematical derivation, which also provides the basis for future signal processing algorithm selection. In addition, almost all the approaches designed to enhance CCA can directly transfer to MSI by the proposed method. Finally, the conclusions are validated with a benchmark data set.

Filter bank approach for enhancement of supervised Canonical Correlation Analysis methods for SSVEP-based BCI spellers.

Canonical correlation analysis (CCA) is one of the most used algorithms in the steady-state visual evoked potentials (SSVEP)-based brain-computer interface (BCI) systems due to its simplicity, efficiency, and robustness. Researchers have proposed modifications to CCA to improve its speed, allowing high-speed spelling and thus a more natural communication. In this work, we combine two approaches, the filter-bank (FB) approach to extract more information from the harmonics, and a range of different supervised methods which optimize the reference signals to improve the SSVEP detection. The proposed models are tested on the publicly available benchmark dataset for SSVEP-based BCIs and the results show improved performance compared to the state-of-the-art methods and, in particular, the proposed FBMwayCCA approach achieves the best results with an information transfer rate (ITR) of 134.8±8.4 bits/minute. This study indeed suggests the feasibility of combining the fundamental and harmonic SSVEP components with supervised methods in target identification to develop high-speed BCI spellers.