Detection Of Mercury Research Articles

Rational design of Au NPs satellite nanostructure modified microelectrode for dual-mode detection of mercury ions in algal solution

Developing a microelectrode with in-situ multiple sensing modes will greatly expand the applicability and reliability of the analytical platform. Hence, a functional substrate with a satellite-like nanostructure was constructed on a gold microelectrode (Au ME). This structure not only amplifies the surface-enhanced Raman scattering (SERS) signal of the labeled molecule (4-nitrobenzenthiol, NBT) on the functionalized Au NPs, but also ensures the good electrical properties of the proposed functionalized microelectrode (Au ME/Au-AuNDNA). Based on this feature, the highly toxic heavy metal mercury ions (Hg2+) were used as a model to verify this dual modal analytical platform. Significantly, the proposed microelectrode has a satisfactory sensitivity to Hg2+and allows the simultaneous presentation of analytical results by dual-mode of SERS signal turn-off (LOD 2.7 × 10−11 M) and current signal turn-on (LOD 6.4 × 10−9 M), the detected concentration of Hg2+ is below the dangerous limit of World Health Organization (WHO) and the U.S. Environmental Protection Agency (EPA). This relies mainly on the formation of thymine-Hg2+-thymine (T-Hg2+-T) by the modified probe B ssDNA on the microelectrode to disrupt the satellite structure with AuNDNA, while the applied potential reduces the Hg2+ captured by T-Hg2+-T on the microelectrode surface. Such a fascinating analytical strategy was further evaluated in an environmental water sample simulated with algal solution and still showed a reliable analytical capability. Thus, the proposed dual-mode sensing concept not only opens new avenues for the coordinated application of novel electrochemical and SERS sensing techniques, but also provides a foundation for in-situ detection based on micro/nanoscale electrodes.

Photoelectrochemical biosensor with Au@PTCA Schottky junction and multiple sandwich structures for Hg2+ sensitive detection

Herein, a novel photoelectrochemical (PEC) biosensor was built on the strength of gold nanoparticles@3,4,9,10-Perylene tetracarboxylic (Au@PTCA) Schottky junction and multiple sandwich structures caused by thymine-Hg2+-thymine (T-Hg2+-T) and base complementary pairing, realizing the highly sensitive detection of mercury ion (Hg2+). The proposed Au@PTCA Schottky junction was formed by using PTCA as carrier and Au NPs as signal enhancer, which could significantly improve photoelectric conversion efficiency, resulting in a strong initial PEC signal. The multiple sandwich structures possessed high steric hindrance effect, which could directly block external electron supply and light harvesting, giving rise to a significantly quenched PEC signal. In addition, the execution of the multiple sandwich structures could extinguish initial PEC signal produced by Au@PTCA Schottky junction, acquiring the comparison of various PEC signals, thereby fulfilling the quantitative detection of Hg2+. The experimental results showed that the PEC signal was gradually suppressed as the Hg2+ concentration increased in the range of 10 pM to 10 μM and the detection limit was 3.33 pM under optimal conditions, giving the sensor the advantages of high selectivity and excellent stability. This study demonstrated a promising method for sensitive detection of Hg2+ and offered a valuable approach with potential applications in environmental detection, biological analysis, and medical research.

Raman Spectroscopy Analysis of the Morphology of Gold Nanoparticles Produced by Laser Ablation in Aqueous Proteinogenic Amino Acid for the Detection of Mercury in Water

Raman Spectroscopy Analysis of the Morphology of Gold Nanoparticles Produced by Laser Ablation in Aqueous Proteinogenic Amino Acid for the Detection of Mercury in Water

The synthesis, characterization and application of the binol-cages of R-/S-enantiomers

In the past few years, significant efforts have been made to create and self-assemble covalent organic cages with increased complexity and functionality. However, although supramolecule cages have been widely recognized as probes to identify metal ions, the detection of mercury ions has not been fully developed. Here, we have designed and synthesized a pair of chiral cages with custom cavities based on the unique rigid structure of 1, 10-binaphthol (binol). Meanwhile, the supramolecular cage has excellent performance in high sensitivity and selectivity for detecting mercury ions. The UV titration results indicate that the binding ratio of the host to guest is 1:5. The titration curve conforms to the nonlinear fitting of the Hill function, which can obtain the binding constant K = 2.57 × 105 M-1 . Furthermore, the detection limit of 1.9 × 10-7 M can be obtained because the absorbance of cages exhibits a strong linear relationship with Hg2+ concentrations. This work provides a new method for selective recognition of ions by supramolecular cages.

Enhancing mercury (II) ion detection with graphene oxide-cerium oxide nanocomposites: Enzyme free ultrasensitive detection

This study discusses how gold (Au) electrodes were modified by immobilizing graphene oxide-cerium oxide (GO-CeO2) nanocomposite to detect mercury (II) (Hg2+) ions selectively. The GO-CeO2 nanocomposite was prepared using the sonochemical method after synthesis of GO through a modifier Hummers’ method and CeO2 via a coprecipitation technique. The structural, morphological, and optical characteristics of the nanocomposite were assessed using X-ray diffraction (XRD), transmission electron microscopy (TEM), and diffuse reflectance spectroscopy (DRS), respectively. Cyclic voltammetry (CV) provided the selective electrochemical response for Hg2+ among different divalent metallic ions. Scan rates (ranging from 5 to 300 mV/s) confirmed the stability of the modified electrode. It was suggested that the Hg2+ ion and modified Au electrode interacted through both diffusion-controlled and surface-controlled mechanisms, with diffusion-controlled interaction being the dominant one. Differential pulse voltammetry (DPV) was chosen to assess sensitivity by conducting concentration profiles in the range of 10 fM to 1 mM. The calculation yielded a limit of detection of 1.87 fM (fM). The developed sensor represents a promising platform for the ultrasensitive detection of Hg2+ ions.

Simultaneous detection of mercury and cadmium ions: A colorimetric method in aqueous media

Hg and Cd are the two most toxic heavy metal ions that could be found in aqueous solutions. In this study, a chemosensor based on 5-(4-((4-nitrophenyl) diazenyl) phenyl)-1,3,4-oxadiazole-2-thiol (DOT) was reported to detect these ions simultaneously. DOT showed high selectivity towards Hg ion by changing the color of the solution from beige to gold-yellow at different concentrations of Hg ion. In comparison, other relevant metals, such as Li+, Na+, K+, Cs+, Mg2+, Ca2+, Al3+, Fe2+, Ag+, Cu2+, Pb2+, Ni2+, Zn2+, Cr3+, Fe3+, Pb4+, Mn2+, and Cd2+ did not affect the color of the DOT solution as the interfering ions. Despite no changes in the color of DOT solution in the presence of Cd ion, a solution containing DOT-Hg complex was changed from gold-yellow to orange by adding Cd ion, providing an approach for detecting Hg and Cd ion simultaneously with UV–Vis and Fluorescent spectroscopy. DOT exhibited a high association constant with a detection limit of 0.05 μM for Hg and Cd ions in an aqueous solution. The results of quantum mechanics (QM) calculations were also consistent with the experimental observations, which indicated that changes in the band gap could explain the various colors of DOT complex with metal ions.

Facile synthesis of nitrogen, sulfur co-doped carbon quantum dots for selective detection of mercury (II)

Facile synthesis of nitrogen, sulfur co-doped carbon quantum dots for selective detection of mercury (II)

A rhodamine NIR probe for naked eye detection of mercury ions and its application

Fluorescence imaging technology has developed rapidly with its advantages, and near-infrared probes are worthy of attention because of their less background interference, low light damage, and infinite potential. Rhodamine and its derivatives have the unique structure of lactam helices, which is an ideal platform for the construction of on-off fluorescent sensors. In this paper, a novel near-infrared fluorescent probe (RBLS) based on rhodamine derivatives was synthesized for the transient detection of mercury ions. The closed-on structure can realize reversible sensor recovery by adding S2-. The superior imaging capability in living cells and in vivo in zebrafish holds promise for biological applications. In addition, the naked eye test strips prepared with RBLS probes can be used to detect and screen Hg2+ in the environment and show good gradient change performance.

Engineering the Ultrasensitive Visual Whole-Cell Biosensors by Evolved MerR and 5' UTR for Detection of Ultratrace Mercury.

The existing mercury whole-cell biosensors (WCBs, parts per billion range) are not able to meet the real-world requirements due to their lack of sensitivity for the detection of ultratrace mercury in the environment. Ultratrace mercury is a potential threat to human health via the food chain. Here, we developed an ultrasensitive mercury WCB by directed evolution of the mercury-responsive transcriptional activator (MerR) sensing module to detect ultratrace mercury. Subsequently, the mutant WCB (m4-1) responding to mercury in the parts per trillion range after 1 h of induction was obtained. Its detection limit (LOD) was 0.313 ng/L, comparable to those of some analytical instruments. Surprisingly, the m4-1 WCB also responded to methylmercury (LOD = 98 ng/L), which is far more toxic than inorganic mercury. For more convenient detection, we have increased another green fluorescent protein reporter module with an optimized 5' untranslated region (5' UTR) sequence. This yields two visual WCBs with an enhanced fluorescence output. At a concentration of 2.5 ng/L, the fluorescence signals can be directly observed by the naked eye. With the combination of mobile phone imaging and image processing software, the 2GC WCB provided simple, rapid, and reliable quantitative and qualitative analysis of real samples (LOD = 0.307 ng/L). Taken together, these results indicate that the ultrasensitive visual whole-cell biosensors for ultratrace mercury detection are successfully designed using a combination of directed evolution and synthetic biotechnology.

Colorimetric Sensing Platform for Detecting Mercury Ions Based on Self-Assembly of a Two-Dimensional Au Nanoparticle Layer

Colorimetric Sensing Platform for Detecting Mercury Ions Based on Self-Assembly of a Two-Dimensional Au Nanoparticle Layer

Carbon dots/Ruthenium(III) nanocomposites for FRET fluorescence detection and removal of mercury (II) via assembling into nanofibers

The determination and removal of mercury(II) (Hg2+) are essential for human health and environmental ecosystems. Herein, an ingenious carbon dots (CDs)-based Förster resonance energy transfer (FRET) system (N, S-CDs/Ru) was fabricated employing CDs and Ru3+ units as energy-transfer doner/acceptor pairs for visual detection and efficient removal of Hg2+. The treatment of Hg2+ induced a remarkable linear enhancement of the ratiometric fluorescence (F613 nm/F478 nm) with a detection limit (LOD) of 95 nM, along with continuous fluorescence color variations from blue to red. Given that the fluorescence color recognition and processing realized the real-time and rapid quantitation of Hg2+ by paper-based smartphone sensing platform. The mechanistic study revealed that the N/S/O-rich surface of the system enabled the Hg2+-triggered self-assembly from dots to nanofibers, combing with the active FRET process. Also, the efficient removal of Hg2+ with a removal efficiency of ∼98 % and an adsorption capacity of ∼372 mg/g was obtained. Furthermore, it was found that N, S-CDs/Ru loaded commercialized SiO2 or SBA-15 could facilitate the removal of Hg2+ with a removal efficiency over 99 % and an adsorption capacity up to ∼562 mg/g. This study provides a potential strategy for environmental monitoring and remediation.

Exonuclease III‑assisted and target-induced conformational change of DNA hairpins for electrochemical detection of mercury (II)

Here, we report a DNA hairpin strategy for electrochemical determination of Hg2+ based on T-Hg2+-T pairs and exonuclease III (Exo III) assistance. The innovation of this work lies in the designed DNA structure and detection principles. Unlike the previously reported DNA hairpin structure, the ring portion of the hairpin DNA we designed consisting of T bases serves as a recognition probe, forming a T-Hg-T complex with Hg2+. The stem is composed of 5 pairs of complementary bases, which is conducive to the stability of the hairpin structure. After the formation of T-Hg-T in the ring, with the help of Exo III, Exo III can digest more DNA than the T bases designed in the stem. In this event, the shorter the length of the remaining DNA strand on the electrode, the weaker the repulsive force against [Fe(CN)6]3−/4−, and the stronger the differential pulse voltammetry (DPV) current signal, achieving “signal-on” transitions. Under the optimal conditions, the DPV current response increases with increasing Hg2+ concentration and is linear with the logarithm of Hg2+ concentration (1 nM–10 μM). The limit ofdetection is 0.16 nM. The electrochemical sensor was successfully applied to the determination of Hg2+ in river water.

Chromogenic probe adhered porous polymer monolith as real-time solid-state sensor for the detection of ultra-trace toxic mercury ions

The escalating predicament of water pollution has spurred the development of new chromogenic materials for the efficient detection/screening of toxic mercuric (Hg2+) ions. In this study, we report a simple and efficient detection stratagem by infusing a chromogenic ion-receptor (BTDA), i.e., 4-(benzothiazol-2-yl)-N, N-dimethylaniline onto a structurally intertwined meso-/macro-pore polymer template for the target-specific sensing of ultra-trace Hg2+. The structural/surface features of the monolithic polymer template, prepared from glycidyl methacrylate (GMA) monomer crosslinked with ethylene glycol dimethacrylate (EGDMA), facilitate voluminous infusion and uniform decoration of ion-receptor molecules across the continuous porous poly(GMA-co-EGDMA) framework, resulting in a solid-state colorimetric sensory system. The bimodal polymer network's intriguing surface and structural morphology of the chromogenic sensor material are interpreted using scanning/transmission electron microscopy, X-ray diffraction, photoelectron spectroscopy, energy dispersive X-ray spectrometry, optical spectroscopy, surface area, porosity and thermal analysis. The proposed Hg2+ sensor offers a linear response range of 1–150 μg/L, with a detection and quantification limit of 0.29 and 0.97 μg/L, respectively. The poly(GMA-co-EGDMA)-BTDA sensor exhibits a quick ion-sensing response (40 s) with distinct color transitions from pastel yellow to olive as a function of increasing Hg2+ concentration. The matrix tolerance studies for the proposed sensory system reveal high selectivity for Hg2+, with a recovery of ≥99.2% in on-site environmental samples. The sensor material exhibits excellent data reproducibility and reliability up to seven cycles of reusability.

A Semi-Automatic Environmental Monitoring Device for Mercury and Cobalt Ion Detection.

A syringe-based, semi-automatic environmental monitoring device is developed for on-site detection of harmful heavy metal ions in water. This portable device consists of a spring-embedded syringe and a polydimethylsiloxane (PDMS) membrane-based flow regulator for semi-automatic fix-and-release fluidic valve actuation, and a paper-based analytical device (PAD) with two kinds of gold nanoclusters (AuNCs) for sensitive Hg2+ and Co2+ ion detection, respectively. The thickness of the elastic PDMS membrane can be adjusted to stabilize and modulate the flow rates generated by the pushing force provided by the spring attached to the plunger. Also, different spring constants can drastically alter the response time. People of all ages can extract the fix-volume sample solutions and then release them to automatically complete the detection process, ensuring high reliability and repeatability. The PAD comprises two layers of modified paper, and each layer is immobilized with bovine serum albumin-capped gold nanoclusters (R-AuNCs) and glutathione-capped gold clusters (G-AuNCs), respectively. The ligands functionalized on the surface of the AuNCs not only can fine-tune the optical properties of the nanoclusters but also enable specific and simultaneous detection of Hg2+ and Co2+ ions via metallophilic Au+ -Hg2+ interaction and the Co2+ -thiol complexation effect, respectively. The feasibility of the device for detecting heavy metal ions at low concentrations in various environmental water samples is demonstrated. The Hg2+ and Co2+ ions can be seen simultaneously within 20 min with detection limits as low as 1.76 nm and 0.27 µm, respectively, lower than those of the regulatory restrictions on water by the US Environmental Protection Agency and the European Union. we expect this sensitive, selective, portable, and easy-to-use device to be valid for on-site multiple heavy metal ion pollution screenings in resource-constrained settings.

A novel visual biosensor for mercury detection based on a cleavable phosphorothioate-RNA probe and microfluidic bead trap

Mercury ion (Hg2+) detection plays a crucial role in safeguarding the environment and protecting human health. In this study, we developed a microfluidic biosensing platform that utilizes a phosphorothioate-RNA (PS-RNA) probe and gold-coated magnetic nanoparticles to quantify Hg2+ visually. The PS-RNA probe was linked to gold-coated magnetic nanoparticles via Au–S interaction and biotin–avidin interaction and then combined with polystyrene microspheres to form a self-assembled structure called a magnetic bead-AuNP-probe-polystyrene (MAPP) bead. We designed and fabricated a microfluidic chip that contained only a magnetic separator and a particle trap. The presence of Hg2+ cut the PS-RNA probe, leading to the separation of magnetic beads and polystyrene microspheres. The MAPP was removed by the magnetic separator, while the cut polystyrene microspheres flowed along the channel and accumulated in the particle trap, forming a long visible strip. The length of the polystyrene microsphere strip was proportional to the Hg2+ concentration. The microfluidic biosensing platform exhibited high sensitivity and specificity for Hg2+ detection, with a detection limit of 21.9 nM. By integrating the microfluidic magnetic manipulation system with a sensitive nucleic acid probe, we developed an automated and visual biosensor that is a valuable reference for the on-site visual detection of heavy metal ions.

Microfluidic Device Integrated With PDMS Microchannel and Unmodified ITO Glass Electrodes for Highly Sensitive, Specific, and Point-of-Care Detection of Copper and Mercury.

This work delves upon developing a two-layer plasma-bonded microfluidic device with a microchannel layer and electrodes for electroanalytical detection of heavy metal ions. The three-electrode system was realized on an ITO-glass slide by suitably etching the ITO layer with the help of CO2 laser. The microchannel layer was fabricated using a PDMS soft-lithography method wherein the mold created by maskless lithography. The optimized dimensions opted to develop a microfluidic device with length of 20 mm, width of 0.5 mm and gap of 1 mm. The device, with bare unmodified ITO electrodes, was tested to detect Cu and Hg by a portable potentiostat connected with a smartphone. The analytes were introduced in the microfluidic device with a peristaltic pump at an optimal flow rate of [Formula: see text]/min. The device exhibited sensitive electro-catalytic sensing of both the metals by achieving an oxidation peak at -0.4 V and 0.1 V for Cu and Hg respectively. Furthermore, square wave voltammetry (SWV) approach was used to analyze the scan rate effect and concentration effect. The device also used to simultaneously detect both the analytes. During simultaneous sensing of Hg and Cu, the linear range was observed between [Formula: see text] to [Formula: see text], the limit of detection (LOD) was found to be [Formula: see text] and [Formula: see text] for Cu and Hg respectively. Further, no interference with other co-existing metal ions was found manifesting the specificity of the device to Cu and Hg. Finally, the device was successfully tested with real samples like tap water, lake water, and serum with remarkable recovery percentages. Such portable devices pave way for detecting various heavy metal ions in a point-of-care environment. The developed device can also be used for detection of other heavy metals like cadmium, lead, zinc etc., by modifying the working electrode with the various nanocomposites.

Spectrofluorometric detection of mercury ions in aqueous medium and cellular milieu using MoS2 nanoflakes

This communication reports the facile hydrothermal synthesis of fluorescent two-dimensional layered MoS2 nanoflakes using a biomolecule (l-cysteine) for efficient and sensitive detection of mercury ions (Hg2+) in aqueous solution by monitoring the fluorescence quenching of MoS2 in a ratiometric approach. This fluorescence quenching of MoS2 was successfully utilized to detect Hg2+ ions in both normal (H9c2 cell line) and cancer (A549 cell line) cells as well via fluorescence imaging microscopy. The as-synthesized MoS2 nanostructured sample was characterized using UV–vis absorption, steady-state fluorescence emission, X-ray diffraction, field emission scanning electron microscopy, high-resolution transmission electron microscopy, and Raman spectroscopy. The strong fluorescence emission of nanostructured MoS2 was heavily quenched by Hg2+ ions in aqueous medium as confirmed by fluorescence spectroscopic results. The binding of Hg2+ with MoS2 nanoflakes and the resulting fluorescence quenching were also supported by Stern–Volmer analysis. The selectivity and sensitivity of the interaction of Hg2+ ions with the as-prepared MoS2 nanoflakes among all other interfering metal ions were analyzed. The selective interaction of Hg2+ with MoS2 was also accompanied by a distinct color change from bluish-green to flaxen or pale yellowish-gray in aqueous medium. The limit of detection of Hg2+ ions in aqueous medium was 0.63 nM. The possible interactions between Hg2+ and MoS2 were confirmed by Fourier transform infrared spectroscopy, time-resolved fluorescence, and cyclic voltammetry studies. Density functional theoretical calculations provided useful information to correlate the electronic structure and energy band distributions with the spectroscopic results for the interaction of Hg2+ with MoS2 nanoflakes. The MoS2 nanoflakes showed no significant cytotoxicity during their interaction with Hg2+ ions in the intracellular medium, as confirmed by MTT assay, thereby ensuring possible future biomedical applications.

Online trace detection of mercury ions with enhanced fluorescence excitation within metal-lined hollow-core fiber.

In this Letter, we present a portable all-fiber fluorescent detection system based on metal-lined hollow-core fiber (MLHCF) for the ultra-sensitive real-time monitoring of mercury ions (Hg2+). The system employs a rhodamine derivative as the probe. The hollow core of the MLHCF serves as both the flow channel of the liquid sample and the waveguide of the optical path. The metal coating in the intermediate layer between the capillary and the polyimide (PI) coating in the MLHCF provides good light confinement, enhancing the interaction between the sample and the incident light for better fluorescence excitation and collection efficiency. Additionally, further enhancement is achieved by placing an inserted filter along the light path to reflect the excitation light back to the MLHCF. A 3-cm length of MLHCF enables simultaneous excitation of a 40-µL sample volume and collection of most of its fluorescent signal in all directions, thereby significantly contributing to its exceptional sensitivity with a limit of detection (LOD) of 2.3 ng/L. The all-fiber fluorescence-enhanced detection device also shows rapid response time, excellent reusability, and selectivity. This system presents an online, reproducible, and portable solution for the trace detection of Hg2+ and provides a promising way for detecting other heavy metal ions.

A novel AIE peptide-based fluorescent probe for highly selective detection of mercury(II) ions and its application in food samples and cell imaging

A novel peptide-based fluorescent probe TPE-PGH was firstly developed based on aggregation-induced emission (AIE) effect. The fluorescence intensity of TPE-PGH was largely ignored in the low water fraction, whereas bright blue fluorescence was observed in the high water fraction. TPE-PGH achieved high selectivity and rapid detection of Hg2+, and has excellent sensitivity to detect Hg2+ with low LOD (58.1 nM). Interestingly, TPE-PGH provided a significant color changed from dark blue to bright cyan upon binding with Hg2+ ions under UV lamp (365 nm). In addition, TPE-PGH was able to simultaneously visualize Hg2+ in living cells with different fluorescence intensities based on excellent cells permeability and low toxicity. Further, TPE-PGH exhibited high precision (RSD < 4 %), and was successfully applied for detecting Hg2+ in real food samples, such as milk, soda drink, red wine, cucumber, tomato and carrot. Successful test strips responses also demonstrated that the potential of TPE-PGH for portable detection of Hg2+ in real samples. Especially, AIE based-test strips soaked in different Hg2+ concentrations was successfully utilized for semi-quantitative detection of Hg2+ using the RGB APP installed on a smartphone, which will provide a new approach for smart and portable detection of contaminated heavy metal ions in food samples.

Sensitive photoelectrochemical detection of Hg2+ with low background noise

Herein, a sensitive photoelectrochemical (PEC) biosensor with low background noise for the detection of the potential heavy metal pollutant mercury ion (Hg2+) was developed based on the Nb.BtsI-assisted Hg2+ cycle strategy as the signal amplification channel and the methylene blue (MB)-double stranded DNA (dsDNA) intercalation complex as the PEC signal indicator. When a trace of target Hg2+ was present, a multitude of output DNA (S2) were released from the preformed reaction platform Au@Fe3O4-H1 through the process of Nb.BtsI-assisted Hg2+ cycling, which greatly amplified the input signal of Hg2+ and thus significantly improved the detection sensitivity of this PEC biosensor. The released S2 could be captured by the 1-hexanethiol (HT)/S1/gold nanoparticles (Au NPs)-engineered biosensing interface to generate steady dsDNA (S1/S2) for embedding numerous photoactive substance MB by π-π stacking, giving rise to the formation of the MB-dsDNA intercalation complex. As a unique PEC signal indicator, the MB-dsDNA intercalation complex could produce significant PEC signals for quantitative determination of Hg2+ from 100 fM to 100 nM. Notably, the introduction of photoelectric signal indicator made the PEC biosensor embrace low background noise and negligible false positive signal, thereby producing the highly enhanced of sensitivity and accuracy. With the assistant of the Nb.BtsI-assisted Hg2+ cycle strategy and the MB-dsDNA intercalation complex, the developed biosensor possessed high sensitivity and excellent accuracy for Hg2+ with a low detection limit of 33.3 fM, demonstrating that the proposed sensing platform was provided with a great application prospect in the field of monitoring and control of environmental pollution concerning Hg2+.