Abstract. In order to compare and analyze the influence of different structural parameters on the muffler performance of multi-section expansion chamber muffler, this paper explores the main factors affecting the noise suppression performance through the transmission loss formula, and it establishes the model of two cylindrical expansion chamber silencer. The muffler expansion chamber is analyzed by changing the section number of the muffler expansion chamber, the cross-section diameter of the front and rear expansion chamber, the length of the front and rear expansion chamber, the length of connecting tube, the arrangement order of expansion chamber with different cross-section area and the arrangement order of expansion chamber with different length. The simulation results show that the muffler volume can be effectively increased by increasing the number of expansion chamber and the cross-section diameter of expansion chamber. The length of the expansion chamber does not show the peak value of the transmission loss curve, which only affects the span of the transfer loss curve; the order of the expansion chamber with different diameters and the arrangement order of the expansion chamber with different lengths have little influence on the transmission loss peak value of the muffler; the change of the length of the connecting tube affects the span of the transmission loss curve, but the peak value of the transfer loss curve is not affected. This study can be used as a reference for the design of a multi-section expansion chamber silencer.