Health Sciences Descriptors Research Articles

The healing effects of using tilapia skin to heal burns and wounds

Introduction: Tilapia skin, a freshwater fish, is being used to treat patients with severe burns. Objectives: The aim of this study was to identify the evidence on the use of tilapia skin in burn healing. Material and Methods: The methodology used was a literature review. The research was carried out by means of an electronic search for scientific articles published on the Scielo (Scientific Electronic Library Online) and Lilacs (Latin American Health Sciences Literature) and Pubmed websites. The health terminologies consulted in the Health Sciences descriptors (DeCS/BIREME) were used; evidence on the use of Tilapia skin in burn healing. Discussion: the good results with Tilapia skin, saline solution, hydrofiber with silver and silver sulfadiazine, however Tilapia skin and its derivatives showed better delineation of the wound edges, reduction of exudate, reduction of crust formation, maintenance of local humidity. This resulted in shorter healing times, fewer dressing changes and less pain related to dressing changes. Histological tests show biocompatibility between human skin and Tilapia skin, and in microbiological tests no bacterial growth was identified, and in biochemical analysis, Tilapia skin showed a higher percentage of type I collagen than observed in human skin, and proved resistant in tensile tests. Conclusion: The studies included in this review showed that the use of Tilapia skin as a biological dressing is effective in the treatment of burns, as it adheres well to the wound bed, has good tensile strength, no antigenicity, and reduces pain. The health care provided to burn patients is carried out directly by the nursing team, who perform all the dressings and assess the healing process. Using Tilapia skin as an alternative dressing for these patients allows nurses to provide better quality care and improve patient comfort.

Linfoma não Hodgkin da Zona Marginal Extranodal Tipo MALT com Acometimento da Coluna Torácica: revisão Sistemática da Literatura e Relato de Caso em um Hospital Universitário no Brasil

Background: Primary bone lymphomas are rare, accounting for less than 1% of non-Hodgkin's lymphomas (NHL). Extranodal marginal zone non-Hodgkin lymphoma of mucosa-associated lymphoid tissue (MALT) arising in the vertebral spine is extremely rare, with only seven cases reported. Methodology: A systematic literature review was conducted on cases from 2012 to 2022 of extranodal marginal zone MALT lymphoma involving the vertebral spine and associated with spinal cord compression. Additionally, a case report from a university hospital in Rio de Janeiro is described. The study was approved by the Research Ethics Committee (approval number: 5.818.416). Searches were performed in SciELO, PubMed, and LILACS databases, using the Health Sciences Descriptors: ("Vertebral Body" OR Spine) AND ("Lymphoma B-Cell Marginal Zone" OR "MALT Lymphoma" OR "Lymphoma of Mucosa Associated Lymphoid Tissue" OR "Mucosa Associated Lymphoid Tissue Lymphoma"). Articles with full texts available in English or Portuguese were selected. Case Description: A 56-year-old female presented with right-sided back pain, progressing to right flank irradiation, lower limb weakness (LLLL), and constitutional symptoms. MRI revealed a solid extradural mass occupying two-thirds of the vertebral canal's diameter, displacing and compressing the dorsal cord to the left. A bone marrow biopsy confirmed infiltration. Laminectomy was performed, and histopathology identified stage IVB extranodal marginal zone MALT lymphoma. Adjuvant chemotherapy led to complete remission. Results and Discussion: The literature review uncovered two relevant case reports. The thoracic spine was the most commonly affected region, and LLLL weakness was the most frequent symptom, with normal laboratory results. Treatment typically involved surgical tumor removal combined with radiotherapy or chemotherapy. Recurrence occurred in both cases, but follow-up showed no evidence of disease. The clinical presentation and exam findings of the current patient were similar to those in the literature, though with bone marrow infiltration. Treatment was consistent with cases in the review, with no recurrence to date. Conclusion: This case represents an uncommon manifestation of primary extranodal marginal zone MALT lymphoma with spinal cord compression, distinguished by bone marrow infiltration—a feature not previously reported in the two cases found in the literature. The case may be considered within the same group of cases reviewed.

Adverse effects resulting from the use of zolpidem hemitartrate: A literature review

Objective: To investigate and discuss the risks associated with the use of the drug in order to clarify the possible damage to health. Methods: Through an integrative review, using the guiding question “What are the main adverse effects and impacts of using zolpidem?”. The search was carried out in the main databases: Latin American and Caribbean Health Sciences Literature (LILACS), Medical Literature and Retrieval System onLine (MEDLINE/PubMed®), Periódicos CAPES and Scientific Electronic Library Online (Scielo). MESH (Medical Subject Headings) and DeCs (Health Sciences Descriptors) were used as descriptors in the search strategy. The search strategy followed the criteria of the Boolean operator “AND”, which combines terms. The terms used were zolpidem “AND” adverse effects AND overdose, during the month of September 2024. Results: Zolpidem is a drug of paramount importance for the treatment of cases of insomnia, and long-term medical therapy should be monitored to assess efficacy, the emergence of adverse effects and the onset or worsening of comorbid conditions. Conclusion: Strict prescription control and continuous evaluation of its impact on patients' physical and mental health are essential to avoid abuse and serious complications.

VIOLÊNCIA DOMÉSTICA E ATENDIMENTO ODONTOLÓGICO: A NECESSIDADE DE UM MANUAL DE CONDUTAS PARA CIRURGIÕES-DENTISTAS

The objective of this study is to help health professionals, especially dentists, know how to identify, approach and appropriately manage the cases of patients who have been victims of domestic violence, by offering clear, evidence-based guidance. It is carried out through a literature review, addressing issues such as oral and maxillofacial trauma associated with domestic violence. The databases consulted included LILACS, SCIELO and PUBMED, the controlled descriptors used and listed by the Health Sciences descriptors (DeCS) were: “Facial trauma”, “Domestic violence” and “Violence against women. The results highlight the need for training health professionals to ensure sensitive care and the importance of collaboration with other areas, such as psychology and social assistance. It is concluded that the implementation of the manual could improve the early detection of abuse and provide more integrated support for victims of domestic violence. Continuous training and awareness raising of dentists are essential to face the ethical and practical challenges related to caring for these patients, contributing to a more effective approach to combating domestic violence.

Etiology, Epidemiology And Methods Of Preventing Sudden Death Of Cardiac Origin In Sports

Introduction: Numerous epidemiological studies have consistently shown an association between moderate aerobic exercise and decreased risk of coronary heart disease (CHD) and death, and even a small amount of exercise provides a significant reduction in risk compared to a sedentary lifestyle Objective: The aim of this study was to identify the etiology, epidemiology and prevention of sudden cardiac death in sports. Methodology: The methodology used was a literature review. The research was carried out by means of an electronic search for scientific articles published on the Scielo (Scientific Electronic Library Online) and Lilacs (Latin American Health Sciences Literature) and Pubmed websites. The health terminologies consulted in the Health Sciences descriptors (DeCS/BIREME) were used; the etiology, epidemiology and ways of preventing sudden cardiac death in sports practices. Discussion: An important distinction must be made between hypertrophic cardiomyopathy and “athlete's heart syndrome”. In this syndrome, intense physical training leads to various morphological and physiological alterations, especially left ventricular hypertrophy. Conclusion: The complete health safety of athletes consists of periodic pre-participation clinical assessment as well as emergency measures, mainly in competition venues, consisting of the availability of health professionals

Low Intensity Laser Therapy: A Review of Its Applications and Effectiveness in Health, General Dentistry and Endodontics

Aims: To evaluate the use of low-level laser therapy in endodontic treatment and its broader applicability in General Health and Dentistry. Study Design: Literature review. Place and Duration of Study: The study involved searching articles and book chapters in the Google Scholar and PubMed databases from 2018 to 2023, with the review concluding in 2024. Methodology: The review used descriptors from the Brazilian Health Sciences Descriptors database: Laser Therapy, Low-Level Light Therapy, Endodontic Treatment, Dentistry, and their Portuguese equivalents. A total of 34 articles were selected, focusing exclusively on low-level laser therapy and its applications. Articles not addressing this specific therapy were excluded. Results: Low-level laser therapy is frequently used as an adjunct in general health, dentistry and endodontic treatment. Clinical applications, such as postoperative pain control, root canal system disinfection, periapical surgery, and tissue repair, showed promising results. However, more theoretical and clinical evidence is still required to fully establish its efficacy. Further research is needed to strengthen the evidence base and optimize its clinical use. Conclusion: Low-level laser therapy offers a potential non-invasive treatment option in endodontics, with satisfactory outcomes in various clinical applications.

Forensic Psychiatry Analysis and Methods for Assessing The Mental Health of A Serial Killer.

Psychosis is a mental illness that causes an alteration in the notion of reality, where a world of its own is formed in the mind of the psychotic, in other words, he lives in a delirium and suffers hallucinations, hearing voices and having bizarre visions. Objectives: To carry out a literature review on Forensic Psychiatry and how to assess the mental health of a serial killer. Method: The methodology used was a literature review. The research was carried out by means of an electronic search for scientific articles published on the Scielo (Scientific Electronic Library Online) and Lilacs (Latin American Health Sciences Literature) and Pubmed websites. The health terminologies consulted in the Health Sciences descriptors (DeCS/BIREME) were used; regarding Forensic Psychiatry and how to assess the mental health disorder of a serial killer.The inclusion criteria were: original article, published in Portuguese and English, freely accessible, in full, on the subject, in electronic format and published in the last years (2010 to 2024), totaling 26 articles. Results and Discussion: While antisocial personality disorder is a medical diagnosis, the term “psychopathy”, which belongs to the psychiatric-forensic sphere, can be understood as a “legal diagnosis”. There is still no effective treatment for so-called “serial killers”. Conclusion: Personality disorders, especially the antisocial type, still represent a real challenge for forensic psychiatry today. The most appropriate and fair place for its sufferers, as well as homogeneous treatment recommendations, are still unanswered questions.

FATORES ASSOCIADOS À QUALIDADE DE VIDA DE CUIDADORES DE IDOSOS COM DEMÊNCIA

The objective of this study was to analyze the factors that influence the quality of life of caregivers of elderly people with Alzheimer's dementia. An integrative literature review study was conducted using the secondary databases Virtual Health Library, Latin American and Caribbean Health Sciences Literature, Scientific Electronic Library Online and Online System for Search and Analysis of Medical Literature based on the specific descriptors retrieved in the Health Sciences Descriptors. The factors associated with the quality of life of caregivers of elderly people with Alzheimer's dementia were burden, functional decline and dependence of the elderly to perform activities of daily living, degree of dementia severity, longer time since diagnosis and living with the demented elderly, socioeconomic conditions, psychological stress and decline in social relationships, environment domain, psychological and physical. It is essential that care is also cared for, both from the point of view of health and in relation to public policies of social security and assistance.

Accidents with Lepidoptera (Insecta): Biology, Poisonous, Clinical Manifestations, Treatment, Prevention, and Therapeutic Possibilities

Accidents triggered by contact with winged adult forms of moths and accidents caused by contact with larvae. These accidents are caused by contact with the bristles on the abdomen of females of certain species, belonging to the genus Hylesia Hübner, 1820 (Family: Hemileucidae). Therefore, the simple fact of penetration of the bristles seems to be capable of causing intense inflammatory, popular, and pruritic reactions. Pararama (pararamose) is the common name for a stinging caterpillar found in the artificial rubber plantations of Pará, Brazil, the larval stage of the moth Premolis semirufa (Walker, 1856) (Famíly: Erebidae). Therefore, accidental contact with the small bristles of the caterpillars or with those of the cocoons causes a chronic inflammatory reaction in the interphalangeal joints that leads to ankylosis. The morbid condition mainly affects rubber tappers and is classified as an occupational disease. Eruca=larva; erucism is poisoning caused by a moth larva. The main families of Lepidoptera fireworms that cause erucism accidents are Megalopygidae, Saturniidae, and Arctiidae. The caterpillars of the Megalopygidae family have a body covered with long, harmless bristles that cover the smaller, sharp spines that carry poison glands this manuscript aims to report the biological characteristics of venomous Lepidoptera (Insecta) and their biological, clinical manifestations, treatment, prevention, and therapeutic possibilities. That paper is a narrative review of the literature, which is designed to explain and discuss a certain subject from a theoretical or contextual perspective, to allow the reader to acquire or update knowledge on a specific topic. The scientific articles that made up this review were searched on Google Scholar, Biological Abstract, HAL, Qeios, ResearchGate, Scielo, and SSRN. The following descriptors in Health Sciences (DeCS) were used: biological therapy, larva, wound, debridement, and healing. The following inclusion criteria were considered: original articles and reviews, published nationally and internationally in full, available electronically, and published in Portuguese, English, and Spanish. The exclusion criteria were dissertations, theses, monographs, and conclusion work, duplicates, and those that required payment to access the content in full.

Compressive Syndrome of the Ostio-fibrous Tunnel at Carp Level - A literary review

CTS tunnel syndrome is characterized by compression of the median nerve inside the carpal tunnel, at the level of the wrist. This disease still has unknown etiology, but it presents itself in a secondary way when related to other pathologies. Compression of the median nerve in the carpal tunnel occurs in most cases of nonspecific chronic flexor tenosynovitis, and it can also occur in many other nosological entities or lesions that occupy space in the tunnel. The prevalence of ostiofibrous tunnel compression syndrome at the carpal level is estimated to be between 4% and 5% of the population, ranging from 51 to 125:100,000, and it occurs more frequently in females, especially between 40 and 60 years of age. The main clinical manifestations include paresthesia in the territory of median nerve sensitivity (particularly in the thumb, index, middle and radial aspect of the ring finger), hyperesthesia (less frequent hypo or anesthesia), wrist pain that may radiate to the fingers, hands, elbows, and in some cases, even the shoulder (such symptoms may disappear with movement of the limb or massage). Diagnosis must be clinical, based on the patient's history and physical examination. For the physical examination, the Tinel and Phalen tests can be used. Complementary tests are used to make a diagnosis, the most recommended being: electroneuromyography (ENMG), magnetic resonance imaging (MRI), computed tomography (CT) and ultrasonography (US). Treatment can be conservative or surgical. The conservative way consists of adopting techniques to alleviate symptoms, such as pain control through wrist orthoses for immobilization, injections and medication, alternative therapies and physiotherapy. Surgical treatment aims to decompress the median nerve and reduce pressure on the carpal tunnel. This approach is adopted when conservative treatment does not lead to an improvement in the clinical condition within 6 to 8 weeks. This paper aims to review the medical aspects of ostiofibrous tunnel compression syndrome at the level of the carpus. The methodology used is analytical in nature through a literature review. The data extracted in the research were from the US National Library of Medicine (PubMed) with the descriptors: median nerve, wrist and carpal tunnel syndrome, according to the Health Sciences Descriptors (DeCS). To perform the crossing of these, the Boolean operator AND was used. 43 articles were found and after inclusion and exclusion criteria, 36 articles were used. Those used for inclusion: articles in English, Portuguese or Spanish, between June 2015 and July 2021, and that were available in full and for free online access. Studies that did not address the relevant concept for achieving the objective were excluded; repeated studies; according to criteria of methodological quality. Thus, the medical evaluation must be performed in a specific way, making it essential to collect the clinical history, physical exams and complementary exams in order to choose to improve conservative therapy and, later, surgical, if necessary. These facts will allow a greater therapeutic success, allowing the greatest well-being to the patient.

Nursing Care For Patients With Stroke Victims: An Integrative Review

The study aims to analyze the nursing care offered to patients who have suffered a stroke; identify the main risk factors and forms of prevention; describe the main conducts adopted by the nursing team to patients suffering from a stroke. As a method, it is characterized as an integrative literature review study. The search was carried out during the months of July and August 2024, in the databases: Medical Literature Analysis and Retrieval Online System (Medline), Latin American and Caribbean Literature in Health Sciences ( Lilacs ), Scientific Electronic Library Online (SciELO), Nursing Database (BDENF), National Library of Medicine (NLM/ PubMed ) and ScienceDirect . Using the combination of descriptors contained in the Health Sciences Descriptors ( DeCS ), the following descriptors were used in English, Portuguese and Spanish: “Stroke Vascular Accident” AND “Nursing Care” AND “Cerebrovascular Accident” in conjunction with the Boolean operator OR. Ten articles were selected. As a result, three categories were highlighted according to thematic similarity: Stroke (CVA) and risk factors; nursing care offered to patients who are victims of Stroke and the conduct adopted by the nursing team in the care of patients with Stroke. Finally, it is of great relevance to highlight the assistance to patients affected by Stroke, thus emphasizing that the nursing area is composed of professionals dedicated to offering assistance and care that aim at both the prevention of the disease, treatment, cure, and the rehabilitation of patients, providing quality assistance, applying conducts based on scientific knowledge

ANÁLISE COMPARATIVA ENTRE A EFICÁCIA DIAGNÓSTICA DA RADIOGRAFIA E ULTRASSONOGRAFIA EM PACIENTES COM PNEUMOTÓRAX

INTRODUCTION: Pneumothorax is a serious medical condition, caused by the presence of air in the pleural cavity, which can lead to serious complications and even be fatal if not treated quickly. Chest radiography is the traditional diagnostic method, but it has limitations, and in this context, ultrasound has stood out as a promising alternative for the diagnosis of pneumothorax, having high sensitivity and specificity in some contexts. OBJECTIVES: This article aims to compare the diagnostic accuracy of ultrasound and chest radiography in the emergency department. METHODOLOGY: We carried out a broad search in several academic databases, using several Health Sciences Descriptors. The objective was to retrospectively compare the diagnostic accuracy of pneumothorax between radiography and ultrasound performed by non-radiologists in emergency patients. RESULTS: This study analyzed the effectiveness of chest radiography and ultrasound in diagnosing pneumothorax. 10 studies were included, 9 of which used the patient as the unit of analysis, with 1170 patients, and 460 with confirmed traumatic pneumothorax. 80% of studies presented a high risk of bias in patient selection. There was heterogeneity in the sensitivity of chest radiography, indicating the influence of the size of the pneumothorax, clinical conditions, and imaging techniques. Ultrasonography showed greater sensitivity and specificity than radiography; however, the results highlight the importance of considering different clinical contexts when choosing the best imaging modality to diagnose pneumothorax in emergencies. CONCLUSION: Thoracic ultrasound performed by non-radiologists is more accurate in diagnosing pneumothorax in emergency room trauma patients than chest radiography. The results highlight the potential of ultrasound as an effective diagnostic tool, easily integrating into trauma care protocols. Its use in medical training programs can improve the speed and accuracy of diagnosing critical conditions such as pneumothorax. The routine use of ultrasound in trauma management can bring positive changes to clinical practice, offering faster and safer interventions to patients.

Characteristics of Venomous Coleopterans and Their Venom with Therapeutic Power (Insecta: Coleoptera)

The medical importance linked to these beetles is because they have a terpene in their hemolymph insect blood that is soluble in various organic solvents, but practically insoluble in water, cantharidin. Only synthesized male cantharidin is stored until mating and transferred to the female at the time of copulation. When molested, these insects expel the toxin through the membranous joints of the body, causing vesicles similar to burns on human skin. Meloid beetles generate a poisonous chemical compound to, among other things, defend themselves from their predators. An international research team involving the Complutense University of Madrid has shown that cantharidin is toxic to several common parasites. The results explain that some birds, such as the great bustard, ingest this type of beetle, among other beneficial properties, due to the antiparasitic activity of cantharidin. The objective of this manuscript was to describe the characteristics of venomous coleopterans and their venom with therapeutic power (Insecta: Coleoptera). This is a narrative review of the literature, which is indicated to explain and discuss a certain subject from a theoretical or contextual perspective, in a to allow the reader to acquire and/or update knowledge on a specific topic. The search for scientific articles that made up this review was carried out on Google Scholar, Biological Abstract, HAL, Qeios, ResearchGate, Scielo, and SSRN. The following descriptors in Health Sciences (DeCS) were used: biological therapy, larva, wound, debridement, and healing. The following inclusion criteria were considered: Original articles and reviews, published nationally and internationally in full, available electronically, and published in Portuguese, English, and Spanish. The exclusion criteria were dissertations, theses, monographs, and conclusion work, duplicates, and those that required payment to access the content in full.

Analysis of interventional cardiological risk in emergency aid: Indications and procedures

Introduction: Interventional cardiology procedures require special preparation recommended in the form of a protocol for each service. It is understood that the need for this is an advance for the ICHS, mainly because anxiety and fear accompany patients. Objetives: The aim of this study is to carry out an up-to-date literature review on information about hemodynamics and interventional cardiology services. Material and Methods: The methodology used was a literature review. The health terminologies consulted in the Health Sciences descriptors (DeCS/BIREME) were used; information on Hemodynamics and Interventional Cardiology services. Results and Discussions: Hemodynamics and interventional cardiology is an area of cardiology that diagnoses and treats diseases of the heart and blood vessels using catheters. The Hemodynamics service is responsible for performing cardiac catheterization for the diagnosis and treatment of heart disease. The department performs the procedure on adults and children. Many patients are referred to the interventional cardiologist after an assessment with the clinical cardiologist. However, some go to the emergency department first because they have symptoms that could be considered serious, such as chest pain or even because they are already having a heart attack. Conclusions: Through procedures such as catheterization, angioplasty, intracoronary ultrasound, among others, interventional cardiology is a procedure without cuts, which allows patients to recover quickly. In this case, it can be used both to treat coronary artery disease, such as angina and heart attacks, as well as structural heart disease, such as problems with heart valves like severe aortic stenosis.

Evaluation of the Efficiency of Neural Enolase (NSA) in the Diagnosis of Viral Encephalitis: A Medical Review

Encephalitis is an inflammation that occurs in the brain when a virus in some cases, bacteria attack it directly, and can also be triggered by other factors. It is an inflammatory process of the meninges, the membranes that cover the central nervous system. Enolase isoenzyme found in neuronal and neuroendocrine tissues. Its levels in tissues other than erythrocytes are negligible. Its measurement is useful for monitoring tumors of neuroendocrine origin, such as neuroblastoma, pheochromocytoma, medullary thyroid carcinoma, small cell lung carcinoma, melanoma, and some pancreatic tumors. NSE concentrations in cerebrospinal fluid (CSF) are often elevated in diseases that result in relatively rapid neuronal destruction. This review aims to evaluate the efficiency of neural enolase (NSA) in diagnosing viral encephalitis. The methodology used an integrative literature review and a synthesis process to develop the study, expand the understanding of knowledge, and achieve the expected results. The integrative literature review is a method that aims to synthesize results obtained in research on a topic or issue, in a systematic, ordered, and comprehensive way. It is called integrative because it provides broader information on a subject/problem, thus constituting a body of knowledge. To carry out the study, a search for scientific articles was carried out through the Virtual Health Library, in the SCIELO, LILACS, and PUBMED databases, using the terminologies registered in the Health Sciences descriptors, encephalitis, enolase, virus, and diagnosis.

Analysis between open and laparoscopic appendectomy. A comparative study of the procedure in Brazil and worldwide

Introduction: The appendix is an organ in the human body that serves as a reservoir for natural bacteria in the gastrointestinal tract and also has an immunological function that is not so well understood. The acute inflammatory process that can occur in this organ is called acute appendicitis and is the most common surgical emergency worldwide. Objectives: To carry out a literature review on the analysis between open and laparoscopic appendectomy, and to compare how this surgery is performed in Brazil and worldwide. Material and Methods: The methodology used was a literature review. The research was carried out through an electronic search of scientific articles published on the Scielo (Scientific Electronic Library Online) and Lilacs (Latin American Health Sciences Literature) and Pubmed websites. The health terminologies consulted in the Health Sciences Descriptors (DeCS/BIREME) were used to analyze open and laparoscopic appendectomy. Discussion: Appendectomy has largely replaced open surgery as the treatment of choice for diseases of the appendix, especially acute inflammation, as it has effective results and some advantages. Video appendectomy did not gain absolute acceptance as quickly as cholecystectomy, for example, and it is only in the last 10 years that this type of minimally invasive approach has excelled the open approach worldwide. Conclusion: According to the literature, laparoscopy has recently become the most prevalent way of performing appendectomy. Despite this trend, the majority of appendectomies were performed by the open route. This can be explained by logistical, financial or medical team preparation issues. Some studies have shown that the rate of complications after surgery in the laparoscopic group was significantly lower than in the open appendectomy group.

Quality of life of professionals working in primary care

Objective: To analyze the factors associated with the quality of life of health professionals working in primary care. Methods: an integrative literature review was conducted using the secondary databases Virtual Health Library, Latin American and Caribbean Health Sciences Literature, Scientific Electronic Library Online and Online System for Search and Analysis of Medical Literature based on the specific descriptors retrieved from the Health Sciences Descriptors. Results: the following factors were identified as associated with the outcome: inadequate conditions to perform work, lack of organization and difficulty in social relationships, professional occupation, with community health agents being the professionals with the lowest quality of life, followed by mid-level professionals, in the qualitative data, the perspectives that most impact the quality of life were infrastructure and salary deficits, Regarding the quality of life domains, there was great variation in the findings of the various studies. Conclusion: the data of the study indicate that the factors that influence the quality of life of professionals working in primary care are complex and multifaceted, ranging from individual variables or to the work environment.

Ecological and Medicinal Importance of Lampreys (Cyclostomata: Petromyzontiformes: Petromyzontidae)

For Pacific lampreys, life is not just about moving from freshwater to saltwater when they reach maturity, these ancient fish have to return to the same river environment where they were born. Going from a saltwater creature to a freshwater creature is not easy, however, and several modifications in appearance and physiology are necessary to survive the dramatic change in salinity. Their return to freshwater is not random, based on chemical signals left by the migration of lamprey larvae to return to rivers They can return to the same place they came from, but, unlike Pacific salmon, this precision is not always guaranteed, however, this transformation and the mapping of rivers require a lot of energy, and the animals resort to parasitization to survive. Lamprey swimming is among the most efficient in the world, as its movements generate zones of low pressure around the body, pulling the body through the water rather than pushing. The objective of this article was to characterize lampreys (Cyclostomata; Petromyzontiformes; Petromyzontidae) regarding their ecological and medicinal importance. The methodological analysis included studies of a particular topic. In its construction process, it is necessary to go through six essential stages: Identification of the theme and selection of the hypothesis or research question; establishment of criteria for inclusion and exclusion of studies/sampling or literature search; definition information to be extracted from selected studies/categorization of studies; evaluation of included studies; interpretation of results; and presentation of knowledge review/synthesis To carry out the study, a search for scientific articles was carried out through Virtual Health Library, in the SCIELO, LILACS, and PUMED databases, using the terminologies registered in the Health Sciences descriptors. Regarding the inclusion criteria, the following were used: Full articles, in Portuguese, and English.

Insulin resistance and metabolic syndrome as a risk factor for Alzheimer's Disease: systematic literature review

Introduction: It is estimated that worldwide, 65.7 million people will live with the disease in 2030, with Alzheimer's disease being the most prevalent in the world, accounting for 60% of dementia cases. The hypothesis was then raised that through the neuroprotective effect of insulin and insulin resistance in the genesis of Metabolic Syndrome, the hypothetical relationship is made that metabolic syndrome is a risk factor for Alzheimer's disease. Objective: The literature that verifies the impact of vitamin D deficiency on the quality of life of individuals undergoing bariatric surgery was reviewed. Methods: The search strategy was carried out in the virtual databases PubMed, Scielo, LILACS, Scopus, Web of Science, Embase, and Biblioteca Virtual em Saúde, in addition to gray literature such as Google Scholar, OpenGrey, Ibict/BDTD (Brazilian digital library of theses and dissertations) and ProQuest using the Medical Subject Headings (MeSH) and Health Sciences Descriptors (DeCS) descriptors with the Boolean logical operators AND, OR and NOT. The studies considered eligible were those that presented metabolic syndrome as a risk factor for the development of Alzheimer's disease. Results: The online search found 216 studies in virtual bibliographic databases and 70 in gray literature. After removing duplicates, 282 articles remained and were read the title and abstract, with 25 articles chosen for full-text reading, leaving 13 that met the inclusion criteria. Most of the studies included corroborated the hypothesis that metabolic syndrome is a risk factor for Alzheimer's disease. Even the two studies that provide some results in which BMI showed a slower decline in cognitive function, stated that the phenotype studied was that of metabolically healthy obese individuals. Conclusion: The results of this study confirmed the idea that there is an interaction between metabolic health and brain health. First, chronic inflammation and oxidative stress associated with metabolic syndrome can cause damage to blood vessels, compromising cerebral blood flow and impairing the supply of essential nutrients to the brain. Additionally, insulin resistance, one of the key components of metabolic syndrome, can hurt brain function by interfering with the absorption of glucose, a vital fuel for the brain. Finally, how changes in blood lipid levels can contribute to the accumulation of beta-amyloid protein plaques in the brain, one of the markers of Alzheimer's disease.

Descripción de los factores genéticos asociados a la conducta suicida y suicidio: una revisión de tema

Introduction: Suicide and suicidal behaviors (SC) are a complex and multidetermined phenomenon in which different genetic, environmental and individual factors interact. The objective of this study was to carry out a review of the genetic factors associated with suicidal behavior described in the literature of the last 10 years. Methods: A search was made of all available articles, both review articles, case reports and management guidelines under the descriptors in health sciences (DeCS) Suicidal behavior, suicide, depression, exome, genetic markers, genetic variation, human genome, serotonin, norepinephrine, dopamine, computational biology in the databases of Google scholar, LILACS, PubMed and ClinicalKe, official websites such as those of the World Health Organization (WHO) and the Ministry of Health and Social Protection of Colombia were consulted. Development: Genetic studies of CS have been trying for decades to find the "suicide gene", in order to prematurely identify those people with a higher risk of making suicide attempts and prevent them from becoming victims; however, these studies failed to find a gene or group of genes that differentiated between suicidal and nonsuicidal subjects. This type of technology gave rise to genome-wide association studies (GWAS), with which some authors wanted to demonstrate the differences in the genome of patients with suicidal ideas. Conclusions: Knowledge of the genetic factors involved may lead to the possibility of identifying individuals with a higher risk of developing suicidal behavior, thus having better tools and receiving a more mechanistic vision to explore the underlying intermolecular network and prevent deaths from it. cause.