Description Of Theory Research Articles

Determination of Elastic Parameters of Lipid Membranes with Molecular Dynamics: A Review of Approaches and Theoretical Aspects.

Lipid membranes are abundant in living organisms, where they constitute a surrounding shell for cells and their organelles. There are many circumstances in which the deformations of lipid membranes are involved in living cells: fusion and fission, membrane-mediated interaction between membrane inclusions, lipid-protein interaction, formation of pores, etc. In all of these cases, elastic parameters of lipid membranes are important for the description of membrane deformations, as these parameters determine energy barriers and characteristic times of membrane-involved phenomena. Since the development of molecular dynamics (MD), a variety of in silico methods have been proposed for the determination of elastic parameters of simulated lipid membranes. These MD methods allow for the consideration of details unattainable in experimental techniques and represent a distinct scientific field, which is rapidly developing. This work provides a review of these MD approaches with a focus on theoretical aspects. Two main challenges are identified: (i) the ambiguity in the transition from the continuum description of elastic theories to the discrete representation of MD simulations, and (ii) the determination of intrinsic elastic parameters of lipid mixtures, which is complicated due to the composition-curvature coupling effect.

Higher form symmetries TFT in 6d

Symmetries and anomalies of a d-dimensional quantum field theory are often encoded in a (d + 1)-dimensional topological action, called symmetry topological field theory (TFT). We derive the symmetry TFT for the 2-form and 1-form symmetries of 6d (1, 0) field theories, focusing on theories with a single tensor multiplet (rank 1). We implement this by coupling the low-energy tensor branch action to the background fields for the higher-form symmetries and by looking at the symmetry transformation rules on dynamical and background fields. These transformation rules also imply a mixing of the higher-form symmetries in a 3-group structure. For some specific and related higher rank cases, we also derive the symmetry TFT from the holographic dual IIA supergravity solutions. The symmetry TFT action contains a coupling between the 2-form symmetry and the 1-form symmetry backgrounds, which leads to a mixed anomaly between the 1-form symmetries of the 5d KK-theory obtained by circle compactification. We confirm this by a pure 5d analysis provided by the 5d effective low-energy Coulomb branch Lagrangian coupled to background fields. We also derive the symmetry TFT for 5d SU(p) supersymmetric gauge theories with Chern-Simons level q and for 5d theories without non-abelian gauge theory description at low-energy. Finally, we discuss the fate of the 2-form and 1-form symmetry of rank 1 6d field theories when coupled to gravity.

Impacts of polarizable continuum models on the SCF convergence and DFT delocalization error of large molecules.

Advances in algorithm developments have enabled density functional theory (DFT) description of large molecules, including whole proteins, but the self-consistent field (SCF) convergence issues often hamper practical applications. The conductor-like polarizable continuum model (CPCM), although initially introduced as an implicit solvent model, was reported to improve SCF convergence in some large molecules. However, the underlying mechanisms and applicable use cases were unclear. We investigated the impacts of CPCM on the SCF convergence of 25 peptides and found that the CPCM only effectively reduced the SCF iterations for molecules with charge separations (e.g., the zwitterionic form of peptides) but had little effect on non-charge-separated molecules. We observed that CPCM increased the HOMO-LUMO gap of both the zwitterionic and non-charge-separated molecules, but only the charge-separated molecules suffered from the vanishing HOMO-LUMO gap problem in the gas phase, which is the origin of the convergence issue. We revealed CPCM's gap-opening mechanism as the selective stabilization/destabilization of molecular orbitals (MOs) based on their local electrostatic environment. Compared to level-shifting, a traditional SCF improvement technique, CPCM has superior performance because the stabilization/destabilization of MOs is consistent through SCF iterations. Finally, we examined CPCM's impacts on DFT density delocalization error (DDE) when used as an SCF accelerator. CPCM can mitigate the DDE and reproduce the density-derived properties (e.g., dipole moments) matching high-level methods when a very low dielectric constant is used but tends to over-localize the electron density at higher dielectric constants.

Relativistic Spin Magnetohydrodynamics.

Starting from the kinetic theory description of massive spin-1/2 particles in the presence of a magnetic field, equations for relativistic dissipative nonresistive magnetohydrodynamics are obtained in the small polarization limit. We use a relaxation-time approximation for the collision kernel in the relativistic Boltzmann equation and calculate nonequilibrium corrections to the phase-space distribution function of spin-polarizable particles. We demonstrate that our framework naturally leads to emergence of the well-known Einstein-de Haas and Barnett effects. We obtain multiple transport coefficients and show, for the first time, that the coupling between spin and magnetic field appear at gradient order in the hydrodynamic equation.

Topological superconductor from the quantum Hall phase: Effective field theory description

We derive low-energy effective field theories for the quantum anomalous Hall and topological superconducting phases. The quantum Hall phase is realized in terms of free fermions with nonrelativistic dispersion relation, possessing a global $U(1)$ symmetry. We couple this symmetry with a background gauge field and compute the effective action by integrating out the gapped fermions. In spite of the fact that the corresponding Dirac operator governing the dynamics of the original fermions is nonrelativistic, the leading contribution in the effective action is a usual Abelian $U(1)$ Chern-Simons term. The proximity to a conventional superconductor induces a pairing potential in the quantum Hall state, favoring the formation of Cooper pairs. When the pairing is strong enough, it drives the system to a topological superconducting phase, hosting Majorana fermions. Even though the continuum $U(1)$ symmetry is broken down to a $\mathbb{Z}_2$ one, we can forge fictitious $U(1)$ symmetries that enable us to derive the effective action for the topological superconducting phase, also given by a Chern-Simons theory. To eliminate spurious states coming from the artificial symmetry enlargement, we demand that the fields in the effective action are $O(2)$ instead of $U(1)$ gauge fields. In the $O(2)$ case we have to sum over the $\mathbb{Z}_2$ bundles in the partition function, which projects out the states that are not $\mathbb{Z}_2$ invariants. The corresponding edge theory is the $U(1)/\mathbb{Z}_2$ orbifold, which contains Majorana fermions in its operator content.

Resolving the pathologies of self-interacting Proca fields: A case study of Proca stars

It has been argued that a self-interacting massive vector field is pathological due to a dynamical formation of a singular effective metric of the vector field, which is the onset of a gradient or ghost instability. We discuss that this singularity formation is not necessarily a fundamental problem but a breakdown of the effective field theory (EFT) description of the massive vector field. By using a model of ultraviolet (UV) completion of the massive vector field, we demonstrate that a Proca star, a self-gravitating condensate of the vector field, continues to exist even after the EFT suffers from a gradient instability without any pathology at UV, in which the EFT description is still valid and the gradient instability in EFT may be interpreted as a standard dynamical instability of a high-density boson star from the UV perspective. On the other hand, we find that the EFT description is broken before the ghost instability appears. This suggests that a heavy degree of freedom may be spontaneously excited to cure the pathology of the EFT as the EFT dynamically tends to approach the onset of the ghost instability.

COGNITIVE THEORY OF METAPHOR BY A.N. BARANOV

The article presents the theses of the descriptive theory of metaphor by A.N. Baranov, which is based on the provisions of the cognitive theory of metaphorization processes. The article analyzes the theories of metaphor, characterizing the role of metaphor in language and in the processes of thinking themselves. Particular attention is paid to the modern theory of conceptual metaphor and its difference from traditional theories.

Pharma 4.0-Artificially Intelligent Digital Twins for Solidified Nanosuspensions.

Digital twins capacitate the industry 4.0 paradigm by predicting and optimizing the performance of physical assets of interest, mirroring a realistic in-silico representation of their functional behaviour. Although advanced digital twins set forth disrupting opportunities by delineating the in-service product and the related process dynamic performance, they have yet to be adopted by the pharma sector. The latter, currently struggles more than ever before to improve solubility of BCS II i.e., hard-to-dissolve active pharmaceutical ingredients by micronization and subsequent stabilization. Herein we construct and functionally validate the first artificially intelligent digital twin thread, capable of describing the course of manufacturing of such solidified nanosuspensions given a defined lifecycle starting point and predict and optimize the relevant process outcomes. To this end, we referenced experimental data as the sampling source, which we then augmented via pattern recognition utilizing neural network propagations. The zeta-dynamic potential metrics of the nanosuspensions were correlated to the interfacial Gibbs energy, while the density and heat capacity of the material system was calculated via the Saft-γ-Mie statistical fluid theory. The curated data was then fused to physical and empirical laws to choose the appropriate theory and numeric description, respectively, before being polished by tuning the critical parameters to achieve the best fit with reality.

The Development and Acceptability of a Wilderness Programme to Support the Health and Well-Being of Adolescent and Young Adult Cancer Survivors: The WAYA Programme.

Detailed descriptions of theory, structure, and activities with causal links to specified outcomes of wilderness programs are lacking. Addressing this gap, the present qualitative study gives a thorough description of the development of the Wilderness programme for Adolescent and Young Adult (AYA) cancer survivors (WAYA). WAYA is adapted to the individual needs of AYA cancer survivors. It was conceived around Næss’s ecosophy and the Positive Health Model, and refined based on findings from a scoping review and patient/public involvement. Programme aims were to increase physical activity, self-confidence, personal growth, joy, safety within nature, meaningful relationships, and self-efficacy. The programme was an eight-day expedition followed three months later by a four-day base-camp. Activities included hiking, backpacking, kayaking, rock climbing, mindfulness and bushcrafting. Evaluation of the programme through focus group and individual interviews with 15 facilitators and 17 participants demonstrated that a diverse group of participants, challenging activities, and mindfulness-based practices were found to positively influence group bonding and the learning process. Furthermore, including an expedition and base-camp component was found to be beneficial in supporting the development of participants’ own personal outdoor practices. In conclusion, this study demonstrated that the WAYA programme is safe and well accepted by AYA cancer survivors.

Relaxation of photoexcited hot carriers beyond multitemperature models: General theory description verified by experiments on Pb/Si(111)

The equilibration of electronic carriers in metals after excitation by an ultra-short laser pulse provides an important class of non-equilibrium phenomena in metals and allows measuring the effective electron-phonon coupling parameter. Since the observed decay of the electronic distribution is governed by the interplay of both electron-electron and electron-phonon scattering, the interpretation of experimental data must rely on models that ideally should be easy to handle, yet accurate. In this work, an extended rate-equation model is proposed that explicitly includes non-thermal electronic carriers while at the same time incorporating data from first-principles calculations of the electron-phonon coupling via Eliashberg-Migdal theory. The model is verified against experimental data for thin Pb films grown on Si(111). Improved agreement between theory and experiment at short times (<0.3ps) due to non-thermal electron contributions is found. Moreover, the rate equations allow for widely different coupling strength to different phonon subsystems. Consequently, an indirect, electron-mediated energy transfer between strongly and weakly coupled groups of phonons can be observed in the simulations that leads to a retarded equilibration of the subsystems only after several picoseconds.

Field Theory of Charge Sharpening in Symmetric Monitored Quantum Circuits.

Monitored quantum circuits (MRCs) exhibit a measurement-induced phase transition between area-law and volume-law entanglement scaling. MRCs with a conserved charge additionally exhibit two distinct volume-law entangled phases that cannot be characterized by equilibrium notions of symmetry-breaking or topological order, but rather by the nonequilibrium dynamics and steady-state distribution of charge fluctuations. These include a charge-fuzzy phase in which charge information is rapidly scrambled leading to slowly decaying spatial fluctuations of charge in the steady state, and a charge-sharp phase in which measurements collapse quantum fluctuations of charge without destroying the volume-law entanglement of neutral degrees of freedom. By taking a continuous-time, weak-measurement limit, we construct a controlled replica field theory description of these phases and their intervening charge-sharpening transition in one spatial dimension. We find that the charge fuzzy phase is a critical phase with continuously evolving critical exponents that terminates in a modified Kosterlitz-Thouless transition to the short-range correlated charge-sharp phase. We numerically corroborate these scaling predictions also hold for discrete-time projective-measurement circuit models using large-scale matrix-product state simulations, and discuss generalizations to higher dimensions.

Meridian study on the response current affected by acupuncture needling direction.

Acupuncture manipulation with needling direction is important for the therapeutic effect based on traditional Chinese medicine theory. However, there is controversy over directional manipulation and therapeutic effect, despite some research showing that acupuncture manipulations may have something to do with therapeutic effect. Moreover, research usually focuses on the therapeutic effects on the acupoints and acupuncture time rather than exploring the manipulation method. This study applies a semiconductor analyzer to investigate the effects of acupuncture manipulation. 10 healthy participants were recruited for the study. We used a cross-over design to compare the effect of different manipulation on individuals. This study employed an Agilent B1500A semiconductor analyzer to investigate the electric characteristics of meridians under directional supplementation and draining manipulation. We measured the electric current of meridians under different manipulation, and compared the difference between supplementation and draining manipulation in healthy individuals. The electric current was significantly larger in supplementation manipulation compared to draining manipulation in the meridians (P < .001). The measured electric current in the same manipulation methods did not show a statistical difference between meridians (P = .094). The different directional manipulation result in different electric currents in humans. Our finding implies that the supplementation and draining manipulation may result in different therapeutic effects clinically as the description of traditional Chinese medicine theory. Therefore, directional manipulation may need to be taken into consideration in future acupuncture studies and clinical management.

Flexibility of fluorinated graphene based memristor structures: current flow model in a multi-barrier system under tensile strain

The flexibility of two types of memristor structures with fluorinated graphene (FG) based active layers (FG with graphene islands on polyvinyl alcohol, FG/PVA, and films from nanoparticles of V2O5 capsulated with FG, FG/V2O5) under the tensile strain in bending conditions was investigated and compared in the present study. Both types of memristors show a similar mechanism of resistance switchings (current paths on traps without filaments). Multi-barrier model of current flow was used to estimate the barrier parameters connected to FG from experiments on resistive switching of memristor structures in the bending condition. The first type of structures (Ag/FG/PVA/Ag) demonstrates the record high values of flexibility: ON/OFF current relation is not changed up to 7% tensile strain created by bending. The second type of structures (Gr/FG/V2O5/Gr with graphene contacts) show a decrease in ON current already for tensile strain more than 2%. The similar mechanism of current flow allows us to use the similar theory for description of the current flow versus the tensile strain. In spite of different structures and morphology of memristors, the typical values of the barrier height extracted from the theoretical description were similar: ∼1.5 eV with an effective barrier thickness of ∼16.5 nm and ∼1.3–1.6 eV with thickness 13.5–15.0 nm for FG/PVA and FG/V2O5 structures, respectively. Increase in the barrier thickness over 19 nm in both cases leads to the strong decrease in ON current of memristors.

Low energy effective theory for axion strings

We consider aspects of the low energy (classical) effective field theory description of global cosmic strings. In the non-relativistic limit, we study the extent to which these are described by the combination of the Nambu-Gotto and Kalb-Ramond actions. While in a formal sense this is the case for infinitely long strings, for more realistic situations, the collective coordinates of the system do not provide a complete description for more than brief intervals; as time evolves it becomes necessary to include low momentum goldstone excitations as well.

The Fallacy Of The Rational Apathy Theory: Minority Shareholder Electronic Participation In Nigerian Corporate Governance

Purpose: The appeal of the Rational Apathy Theory lies in the fact that it is not only a descriptive theory of shareholder behaviour in the modern public firm but also a powerful normative tool which recommends itself to corporate legislators and policymakers. True to their normative logic, proponents of apathy contend that since shareholders of modern public firms will never find it cost-efficient or incentivized to perform their monitoring responsibilities over corporate management, insisting on a shareholder-oriented corporate governance model is undesirable. This article rejects the determinism and immutability of the above thesis and argues that firm investors will embrace activism where the cost of corporate monitoring is reduced, and the benefits of doing so are increased. Given the ability of the internet to reduce monitoring costs for shareholders (predominantly minority shareholders) in public companies, the article campaigns for minority shareholder electronic participation in corporate governance and proposes a careful reform of corporate law and governance in post-covid Nigeria, drawing inspiration from similar reforms on electronic governance in Canada, UK, and the State of Delaware in the US. In a society where digitalization has been identified as a major catalyst for the economic revival of commercial and corporate life, this article recommends itself to policy and lawmakers, corporate boards, corporate law experts, legislators, regulators, and other relevant stakeholders. Methodology: The article adopts doctrinal and comparative methods of legal analysis. Results/Findings: The article finds that while the Rational Apathy Theory may have served the analogue world, it is unsuitable for a digital generation, where issues of cost, communication and participation could be liberalized, through the use of the internet, to serve the interest of shareholder democracy in public companies.

Noncompactified Kaluza–Klein Gravity

We present a brief description of noncompactified higher-dimensional theories from the perspective of general relativity. More concretely, the Space–Time–Matter theory, or Induced Matter theory, and the reduction procedure used to construct the modified Brans–Dicke theory and the modified Sáez–Ballester theory are briefly explained. Finally, we apply the latter to the Friedmann–Lemaître–Robertson–Walker (FLRW) cosmological models in arbitrary dimensions and analyze the corresponding solutions.

Construction and Research of Converged Media Random Matrix Model and Multivariate Evaluation System

According to the indicators, the evaluation index system of convergent media communication efficiency is constructed, and its corresponding hierarchical structure model is constructed. According to the nine-level scale in the analytic hierarchy process, the indicators are scored by designing an expert questionnaire with weights of relevant indicators, and a pairwise comparison judgment matrix is constructed from the questionnaire data obtained through the expert consultation questionnaire. This paper uses the YAAHP analytic hierarchy process software to calculate the matrix results and test the final results. If the obtained results are within the consistency test range, it will pass; otherwise it will not pass. The fine-tuning matrix is processed, and the weight vector is calculated to obtain the final indicator weight result. After studying a class of using matrix factorization to enhance the independence of random matrix column vectors, a Gram-Schmidt orthogonalization of random matrices is proposed to minimize the intrinsic correlation of the matrix. After analyzing the reconstruction characteristics of the orthogonal matching pursuit algorithm, a new signal reconstruction algorithm is given by combining the new optimization method with the reconstruction algorithm. Referring to the relevant theories of physics and molecular dynamics, this paper draws on the relevant description of the information fusion theory, introduces the basic concepts of “energy” and “collision,” and constructs the energy description model before data object fusion and the collision model when data objects are fused. By combining the practice of the radio mobile client log access and record data resources that have completed situation assessment and state transition, it effectively handles many low-efficiency regional data object processing problems generated in the process of data object fusion and deepens data object fusion.

A Skeletal Model for 2hbox {d} Conformal AQFTs

A simple model for the localization of the category mathbf {CLoc}_2 of oriented and time-oriented globally hyperbolic conformal Lorentzian 2-manifolds at all Cauchy morphisms is constructed. This provides an equivalent description of 2-dimensional conformal algebraic quantum field theories (AQFTs) satisfying the time-slice axiom in terms of only two algebras, one for the 2-dimensional Minkowski spacetime and one for the flat cylinder, together with a suitable action of two copies of the orientation preserving embeddings of oriented 1-manifolds. The latter result is used to construct adjunctions between the categories of 2-dimensional and chiral conformal AQFTs whose right adjoints formalize and generalize Rehren’s chiral observables.

Doubled space and extended supersymmetry

The doubled formulation of the worldsheet provides a description of string theory in which T-duality is promoted to a manifest symmetry. Here we extend this approach to mathcal{N} = (2, 2) superspace providing a doubled formulation for bi-Hermitian/generalised Kähler target spaces. The theory is described by a single function, a doubled-generalised Kähler potential, supplemented with a manifestly mathcal{N} = (2, 2) constraint. Several examples serve to illustrate this construction, including a discussion of the mathcal{N} = (2, 2) description of T-folds.

Ethics and Behavior of Bureaucracy In Support Strengthening Good Governance

Bureaucrats' ethics and behavior are important aspects in referring to the implementation of good governance functions. This study aims to examine and find out whether the ethics and behavior of the apparatus is really able to provide reinforcement to the implementation of good governance. The method used in this paper is Descriptive Method with desk study study analysis, which is a study of the description of theories, concepts, or research results related to the focus of the study. The results showed that the ethics and behavior of bureaucrats play a role in shaping bureaucratic values and can strengthen the concept of governance in a government.