Control Department Research Articles

Association between ambient air particulate matter and human health impacts in northern Thailand

Air pollution in Thailand is regarded as a serious health threat, especially in the northern region. High levels of particulate matter (PM2.5 and PM10) are strongly linked to severe health consequences and mortality. This study analyzed the relationship between exposure to ambient concentrations of PM2.5 and PM10 by using data from the Pollution Control Department of Thailand and the burden of disease due to an increase in the ambient particulate matter concentrations in northern Thailand. This study was conducted using the Life Cycle Assessment methodology considering the human health damage impact category in the ReCiPe 2016 method. The results revealed that the annual average years of life lived with disability from ambient PM2.5 in northern Thailand is about 41,372 years, while from PM10 it is about 59,064 years per 100,000 population. The number of deaths from lung cancer and cardiopulmonary diseases caused by PM2.5 were approximately 0.04% and 0.06% of the population of northern Thailand, respectively. Deaths due to lung cancer and cardiopulmonary diseases caused by PM10, on the other hand, were approximately 0.06% and 0.08%, respectively. The findings expressed the actual severity of the impact of air pollution on human health. It can provide valuable insights for organizations in setting strategies to address air pollution. Organizations can build well-informed strategies and turn them into legal plans by exploiting the study’s findings. This ensures that their efforts to tackle air pollution are successful, in accordance with regulations, and contribute to a healthier, more sustainable future guidelines on appropriate practices of air pollution act/policy linkage with climate change mitigation.

RP-HPLC Method Development and Validation for the Estimation of Lafutidine using Bulk and Pharmaceutical Dosage Forms

A simple and selective LC method is described for the determination of Lafutidine in tablet dosage forms. Chromatographic separation was achieved on a c18 column using mobile phase consisting of a mixture of Phosphate buffer (KH2PO4) pH4.0: Acetonitrile (30:70v/v/v), with detection of 299nm. Linearity was observed in the range 60-140µg/ml for Lafutidine (r2 =0.999) for the amount of drugs estimated by the proposed methods was in good agreement with the label claim. From the above experimental results and parameters it was concluded that, this newly developed method for the simultaneous estimation of Lafutidine was found to be simple, precise, accurate and high resolution and shorter retention time makes this method more acceptable and cost effective and it can be effectively applied for routine analysis in research institutions, quality control department in meant in industries, approved testing laboratories, bio-pharmaceutical and bio-equivalence studies.

Investigation of Acinetobacter baumannii Outbreak in a Burn Unit Revealed a Surprising Environmental Source.

We describe an outbreak of Acinetobacter baumannii in a 15-bed regional burn unit in an academic tertiary care medical center, and the investigations and control measures used to halt the outbreak are described.Nine cases of A. baumannii were reported in our burn unit in a one-year period, which was higher than our expected number of two-three cases per year. Our burn unit director requested an outbreak investigation, and our hospital's infection control department investigated thoroughly and found a source for that outbreak, which was never reported as a source in the previous literature. We identified table fans as the source of this outbreak. We then developed a strict fan policy, and after implementation of the policy, and terminal cleaning of rooms, only two cases per year of A. baumannii were reported in the next three-year period. We concluded that the table fans were colonized with A. baumannii and since they were used interchangeably in all patient rooms, caused this outbreak. There are no specific joint commission guidelines for the use of fans in hospitals. While fans can be used for the comfort of the patient, we should be cautious not to spread infections.

The role of online marketing to engage healthcare workers with infection prevention and control information and resources: A pilot study.

The successful adoption and application of infection prevention and control (IPC) principles in all healthcare settings is dependent on the degree to which healthcare workers (HCWs) are aware of the requirements, have access to program resources and information, and engage with the IPC program. This study investigates the impact of redesigning the Infection Control Department (ICD) intranet site based on user feedback followed by a targeted marketing campaign to improve website usability, awareness, and access. In this systematic study, we used a survey plus two focus group interviews to elicit user requirements for the content and look of the ICD intranet page and identify the best communication platforms to use for the marketing campaign to launch the redesigned intranet page. The information was used to redesign the intranet page and develop the marketing campaign. The survey was repeated post-intervention and these results, along with a comparison of website analytics monitoring traffic, were used to determine the success of the intervention. The ICD intranet page redesign increased the information and resources. Post-intervention survey results demonstrated a significant improvement in user satisfaction including ease of navigation and access to IPC information and resources. The marketing campaign resulted in a significant increase in website traffic to the ICD intranet page, demonstrating enhanced engagement with HCWs. This study demonstrated that website redesign based on user feedback, combined with a marketing campaign, can increase the traffic to the website and improve the user experience when accessing and navigating the site making the information and resources more accessible to HCWs.

Biosynthesises of Silver Nanoparticles of Beauveria bassiana and its Effect on Potato Tuber Moth (Zeller) Phthorimaea opercullella Lepidoptera: Gelechiidae

The study was conducted at the Atomic Energy Laboratory, plant Control Department / Baghdad for the year 2020-2021. The study aimed to synthesis of silver nanoparticles from Beauveria bassiana to control potato tuber moth Phthorimaea opercullella. The results showed the formation of silver nanoparticles of the supernatant B.b-SNPS of the fungal extract and biomass B.b-SNPS had the highest absorption at the longest wavelengths (380 and 435 nm) respectively. The scanning electron microscope images also showed that the silver nanoparticles were of irregular spherical shapes with average diameters of Bb-AgNPs for biomass and Bb-AgNPs for the supernatant (43.75 and 79.65) nanometers, respectively. The results showed that the silver nanoparticles prepared by the supernatant and the biomass of the fungus induced the highest egg mortality of 34.6% and 44.3%, while the egg mortality were 80.9 and 67.5%, respectively, when the fourth larval stage of the insect was treated. The overall results indicated that the prepared silver nanoparticles are highly efficient in affecting the eggs and larvae of the fourth instar, which can be used efficiently to reduce the rate of infection in the insect and can be a promising method for the insect control.

The Relationship between the Control Environment and Effectiveness of Internal Control, Research in Vietnamese Life Insurance Companies

The article has presented the theoretical basis of the control environment and the factors that make up the control environment in the enterprise. Building a controlled environment is one of the principles of internal control, these two factors have a relationship, support, and promote the completion and effectiveness of each other. Research results have shown the importance of internal control for businesses. Identify limitations in the control environment such as insurance enterprises not issuing specific policies on integrity and ethical values; the element of commitment on capacity not being guaranteed; The internal control department is not completely independent from the business management apparatus or the policy on training and retaining personnel has not been respected. Along with the new regulations in the Law on Insurance Business, the life insurance industry development project developed by the Vietnamese government has provided a solid basis for businesses to improve the control environment, thereby improving the quality-of-life effective internal control. The research team also based on the existing points and the ability to improve the effectiveness of internal control to propose some solutions to improve the control environment. Accordingly, creating a controlled environment in the insurance business, focusing on business ethics, perfecting the organizational structure in a compact direction, ensuring the efficiency of each department, and ensuring the good implementation of the objectives of the unit, separating the activities of the Board of Directors and the internal control department, limiting the overlapping task assignment and regularly renewing the human resource policy are the solutions offered.

THE IMPACT OF GREEN ECONOMY STANDARDS ON COMPETITIVE ADVANTAGE: THE STUDY OF ROMANIA

The study aimed to reveal the impact of green economy practices in achieving competitive advantage in companies operating in Romania, according to the size of the companies. The study used the descriptive causal approach. As for the study population, it consisted of all employees in Romanian companies in the departments of quality assurance, quality control, research and development, and production. The questionnaire was used as a main tool for collecting data and information that was analyzed with a set of statistical means, via the Internet to collect data, followed by the analysis of correlations between specific variables. By applying the Pearson chi-square test, 355 questionnaires were distributed, and only 100 were retrieved. The results of the study have showed that there is an impact of green economy practices in achieving competitive advantage, as well as an impact of total quality management practices in achieving competitive advantage in the Romanian operating companies under study. There were no statistically significant differences in the averages of the impact of green economy practices on achieving the competitive advantage. There is a relationship between the use of green economy standards and the subsequent perception of their effectiveness.

Retrospective analysis and modern spatiotemporal characteristics of tularemia in the territory of the West Kazakhstan and North Kazakhstan regions

Rationale. An important task is to monitor the incidence of tularemia among the population of Kazakhstan. Natural foci of this infection occupy large areas. In some regions with large numbers of rodents and ectoparasites and low vaccination coverage, human cases of tularemia have been reported.The aim of the study. To carry out retrospective analysis and to study modern spatiotemporal characteristics of tularemia in the West Kazakhstan and North Kazakhstan regions in order to improve the effectiveness of preventive measures.Materials and methods. In our work, we used public records, the results of an epizootological survey of tularemia natural foci and the official data from the Departments of Sanitary and Epidemiological Control of two regions on the human cases of tularemia in 2000–2021. We used descriptive statistics methods, relative and absolute indicators of the tularemia incidence in the population for the analysis. The phenotypic and genetic properties of the strains isolated in 2000–2021 were studied according to the guidelines.Results. A retrospective analysis of the tularemia incidence among the population of the North Kazakhstan and West Kazakhstan regions showed an improvement in the epidemic situation. Over the past 20 years, 4 human cases of tularemia have been registered in the West Kazakhstan region, while the epizootic potential was quite high; more than 300 strains of the tularemia microbe were isolated during the studied period. In the North Kazakhstan region from 2000 to 2021, 11 human cases of tularemia were registered; when studying rodents, mammals and environmental objects, single positive samples for specific tularemia antibodies and antigens were detected; no strains of tularemia microbe were isolated.Conclusion. An analysis of long-term data on the epizootic and epidemic activity of tularemia natural foci, processed using descriptive statistics and GIS technology, made it possible to identify places of long-term persistence of the tularemia agent in the natural focus of the North Kazakhstan and West Kazakhstan regions and to create an electronic map of the territories endemic for tularemia to determine the scope of preventive measures.

Classification of hundreds of classes: A case study in a bank internal control department

The main function of the internal control department of a bank is to inspect the banking operations to see if they are performed in accordance with the regulations and bank policies. To accomplish this, they pick up a number of operations that are selected randomly or by some rule and, inspect those operations according to some predetermined check lists. If they find any discrepancies where the number of such discrepancies are in the magnitude of several hundreds, they inform the corresponding department (usually bank branches) and ask them for a correction (if it can be done) or an explanation. In this study, we take up a real-life project carried out under our supervisory where the aim was to develop a set of predictive models that would highlight which operations of the credit department are more likely to bear some problems. This multi-classification problem was very challenging since the number of classes were enormous and some class values were observed only a few times. After providing a detailed description of the problem we attacked, we describe the detailed discussions which in the end made us to develop six different models. For the modeling, we used the logistic regression algorithm as it was preferred by our partner bank. We show that these models have Gini values of 51 per cent on the average which is quite satisfactory as compared to sector practices. We also show that the average lift of the models is 3.32 if the inspectors were to inspect as many credits as the number of actual problematic credits.

Risk of Coronavirus Disease 2019 (COVID-19) in Special Military Operations in Southern Thailand, 2021

On 12 Oct 2021, the Department of Disease Control received notification of a coronavirus disease 2019 (COVID-19) cluster in a military camp in Southern Thailand. Together with local health authorities, we investigated the outbreak with the aim of describing case characteristics, identifying risk factors, and providing control measures. We conducted a descriptive study by reviewing laboratory results and medical records, as well as interviewing the cases and military staff. A retrospective cohort study was undertaken to determine the potential risk of COVID-19 by Poisson regression with robust standard errors. Of 188 military members, 37 were confirmed cases (attack rate 19.7%). The attack rates among males and females were 28.97% and 10.71%, respectively. Almost all cases (97.30%; 36/37) had mild symptoms and one was asymptomatic. Attending a special operation where soldiers were tasked to go on outreach in communities or in the forest (adjusted risk ratio (RR) 2.75 [95% CI 1.60–4.75]) and engaging in high-risk behaviors (adjusted RR 3.41 [95% CI 1.64–7.06]) were risk factors, while completing 2-dose vaccination schedule (adjusted RR 0.56 [95% CI 0.31–1.00]) had a protective effect. We recommend that strict symptom monitoring measures be implemented among special operation forces, efforts be made to promote personal hygiene, and we encourage all military staff to undergo full vaccination.

River Flood Characteristics Along the Canal Area Effected By Hanzhuang Canal Jacking

In this paper, flood characteristics along the canal area effected by Hanzhuang Canal jacking are studied. By coupling the rainfall runoff (NAM) model with the hydrodynamic (HD) model, a 1-D hydrologic-hydrodynamic coupling model was built. On the basis of parameter calibration and model validation, different flood simulation schemes are drawn up, and the influence range of Hanzhuang Canal jacking and the flood characteristics of tributaries affected by Hanzhuang Canal jacking are analyzed respectively. The results show that with the increasing discharge of Hanzhuang Canal, the water level of Hanzhuang canal rises gradually, the main stream flood flows upstream along the tributaries, the water level of the tributaries rises gradually, and the risk of flood disasters increases. Among the tributaries, Taogou River is most affected by Hanzhuang Canal jacking and has the highest risk of flood disaster, followed by Dasha River, Dasha River Floodway and Sizhi Ditch. The results also show that the backwater of Hanzhuang Canal on the tributaries is mainly reflected in the influence on the upstream flood water level process, but has little or no influence on the flood discharge process, which can provide a reference for regional flood control and scheduling department.

An Effective Imputation Method Using Data Enrichment for Missing Data of Loop Detectors in Intelligent Traffic Control Systems

In intelligent traffic control systems, the features extracted by loop detectors are insufficient to accurately impute missing data. Most of the existing imputation methods use only these extracted features, which leads to the construction of data models that cannot fulfill the required accuracy. This deficiency is the main motivation to propose an enrichment imputation method for loop detectors namely EIM-LD, in which the imputation accuracy is increased for different missing patterns and ratios by introducing a data enrichment technique using statistical multi-class labeling. It first enriches the clean data by adding a statistical multi-class label, including C1…Cn classes. Then, the class of samples in the missed-volume data is labeled using the best data model constructed from the labeled clean data by five different classifiers. Experts of the traffic control department in Isfahan city determined classes of the statistical multi-class label for n = 5 (class labels), and we also developed subclass labels (n = 20) since the number of samples in the subclass labels was sufficient. Next, the enriched data are divided into n datasets, each of them is imputed independently using various imputation methods, and their results are finally merged. To evaluate the impact of using the proposed method, the original data, including missing volumes, are first imputed without our enrichment method. Then, the proposed method’s accuracy is evaluated by considering two class labels and subclass labels. The experimental and statistical results prove that the proposed EIM-LD method can enrich the real data collected by loop detectors, by which the comparative imputation methods construct a more accurate data model. In addition, using subclass labels further enhances the imputation method’s accuracy.

Reevaluating the Significance of Infection Preventionists and Infection Prevention and Control Departments in the Post-COVID-19 Era.

Infection preventionists are specialized health care professionals tasked with developing and implementing infection control policies, educating staff and patients on prevention practices, and investigating outbreaks. Infection preventionists role in developing effective measures for infection prevention and control and ensuring public health and safety became even more vital given the emergence of the COVID-19 pandemic. It is important for health care systems and institutions to incorporate lessons learned, enhance infection prevention and control resources, and grow the infection preventionists workforce to prepare for future pandemic events.

POTENTIAL IMPACT OF NITROGEN ON POPULATION FLUCTUATION OF APHID AND YIELD PARAMETERS IN BARLEY

The present study was carried out on the farmer field under the supervision of the Department of Plant Protection and Quality Control of Pesticides during 2020 and 2021. Barley cultivar ‘Haider-93’ was sown in a randomized complete block design (RCBD) with three replications to examine the effect of two levels ofnitrogen fertilizer, 50 and 100 kg/ha along with control (no fertilizer), on population fluctuation of aphid and on barley yield components like grain protein (%), 1000-grain weight and the barley grain yield. Aphid incidence was recorded throughout the cropping season. The results revealed that peak infestation of aphids per tiller were recorded in the 3rd week of February in successive year. The study indicated a significant relationship between nitrogen fertilizer and aphid population density per tiller. The mean aphid population per tiller was recorded a significantly higher (34.12 ± 0.81 and 28.65 ± 0.17 for the years 2020 and 2021, respectively) at 100 kg/ha of nitrogen level while lowest infestation (14.51 ± 0.20 and 12.30 ± 0.10 aphids per tiller for the year 2020 and 2021, respectively) was recorded at 0 kg/ha of nitrogen fertilizer. Nitrogen fertilizer level at 100 kg/ha gave significantly higher grain protein (12.80 ± 0.17 and 13.70 ± 0.26% for the years 2020 and 2021, respectively) and grain yield (2758.75 ± 60.82 and 2673.79 ± 61.88 kg/ha produce for the year 2020 and 2021, respectively) of the barley crop. However, treatment differences for 1000-grain weight (g) were recorded as non-significant. These findings suggest that the nitrogen fertilizer at 100 kg/ha level produced significantly higher grain protein (%) and grain yield at the same time, also supported the higher infestation of aphids per tiller. Still, this aphid density did not affect the accumulation of grain protein (%) and grain yield of the barley crop. The results of this study might be used for decision-making to apply nitrogen fertilizer for better grain yield of barley crop but at the same time considering the colonizing aphid population.

Analisis Pengendalian Kualitas Guna Meminimalsir Deffect Dengan Pendekatan Metode Statistical Quality Control (SQC) (Studi Kasus di PT. Romi Violeta Sidoarjo)

PT Romi Violeta Sidoarjo is one of the furniture companies in Indonesia, specializing in rattan and wood products, offering them to the global market. Quality is also a key factor for the company, as good quality is considered an achievement. In the production process, there are inevitably product errors that do not meet specifications or defects, one of which occurs during the finishing process, where there are 8 types of defects. In the data of the quality control department for finishing in the year 2022, there were 246 instances of defects out of a total production of 10,921. This can hinder further production processes, and the company will incur losses due to costs and expenses for repairing defective products. The research is conducted with the aim of determining the level of product quality control, the causes of product defects, and preventive actions or improvement proposals to reduce the defect rate. The method used in this research is Statistical Process Control (SPC), which aims to minimize the defect rate. From the calculations and analysis of the Statistical Process Control (SPC) results for the eight types of defects, the dominant defect type is color variation, which accounts for 67 instances with a percentage of 27.2%. Furthermore, on the control chart calculations, findings were made for the data samples in January, June, August, and September. The cause-and-effect diagram revealed factors such as human, machine, raw materials, methods, and the environment that can contribute to defects. However, the largest cause is human error, as almost 90% of the finishing work is done by humans, often without following the Standard Operating Procedures (SOP) set by the company.

Home Security and Alerting System

People have always been quite concerned about security. Security issues have existed since the beginning of time, and there is never enough security. With the rise in theft, robbery, and other criminal activity, it is always a concern to ensure the safety of one's possessions when leaving one's home. Home security systems are needed for occupants' convenience and safety. There are numerous automatic devices available that can alert the home's owner from any intrusion or attempted intrusion. This paper presents the solution to the faced problem, The implemented system uses the GSM module, relevant sensors, and integration with the Arduino. The system utilizes the sensor to detect any malpractices and hazards and then send the alert with the coordinates of the victim's place to the nearest fire control department or the police forces at the time of need. The implemented system acts as a prototype but displays prominent results in the field of security.

Development and Validation of RP-HPLC Method for the Simultaneous Estimation of Bilastine and Montelukast in Tablet Dosage Form

Place of Study: Department of Pharmacy, University College of Technology, Osmania University, Hyderabad, Telangana.
 Aim: The present study is describing about the development of a new RP-HPLC method for the simultaneous estimation of Bilastine and Montelukast in Active Pharmaceutical Ingredient (AI) and commercial formulations.
 Methodology: In the present investigation, an Inertsil ODS C18 column dimensions of 250 mm length x 4.6 Internal diameter x 5-micron particle size has been chosen. Phosphate buffer and acetonitrile were opted as isocratic mobile phase at a ratio of 30:70, with a flow rate of 1 ml/min. The pH of the developed buffer was maintained at 4.6 and the temperature was set at room temperature. The wavelength of Bilastine and Montelukast was observed at 260 nm. For both Bilastine and Montelukast the retention time has been observed at 2.319 and 4.299 minute correspondingly. The percentage purity of both the drugs was found to be 100.6 % and 100.3 % correspondingly. The developed method satisfied all the system suitability parameters for Bilastine and Montelukast and the observed values for theoretical plates were found to be 1.3 and 1.4 respectively, tailing factor were found to be 5117.5 and 3877.8 respectively with a resolution of 9.0.
 Results: Finally, the method was validated by parameters such as precision, accuracy, robustness and ruggedness. The linearity and range were from 1-5µg and 100-500 µg concentrations series, the correlation coefficient for both the drugs was noted to be 0.999 while the mean percentage recovery was observed at 100.1 percent & 100.4 percent. The % RSD for repeatability was found to be 0.31 and 0.38. The % RSD of intermediate precision was found to be 0.12 & 0.15 correspondingly. The LOD values were found as 2.94, 3.03 and for the LOQ values were found as 9.87, 10.1.
 Conclusion: The developed method which was validated was observed to be novel, accurate, simple, robust, precise, repeatable for the present study with a suitable RP-HPLC technique to concurrently determine Bilastine and Montelukast present in the commercial formulation. This developed method is useful on daily basis due to their accurate results, reproducibility, robustness for the estimation of samples in routine quality control departments.

QUALITY MANAGEMENT PRACTICES IN GONDRANG-PULCHOWK SIX-LANE ROAD UPGRADING PROJECT AT CHITWAN DISTRICT, NEPAL

The objective of this study is to assess the current quality management practices, determine the factors affecting quality management and to find out remedial measures that will improve the quality management practices in Gondrang-Pulchowk six-lane road construction project.This research methodology is based on interviews and questionnaires survey with clients and contractors who were involved in the project as well as experts from related field. Statistical tools, relative importance index, validity and reliability tests, Spearman’s correlation tests were used for the ranking of different quality aspects.From the comparative study, it was found that most guidelines of the General Conditions of Contract, Special Specifications and Quality Assurance Plan of the contract document were met during project execution although few concerns of safety and correspondence remain to be addressed.From the questionnaire survey, it was found that the practices to achieve quality need to be improved. Contractors consider cost factors as major factor affecting quality in the project whereas lack of supervision by contractors is cited by the clients as major factor affecting quality. To overcome the challenges of quality, proper material selection and usage, inspection, quality training, setting up quality department are seen as remedial measures. Improving safety at site, maintaining written correspondence, incorporating elements of ISO, proper selection and usage of materials, holding quality trainings and setting up quality control department are recommended for this project.

Tripartite evolution game between susceptible and infected groups and the governmental prevention and control department amid major epidemics

A major epidemic is an evolutionary process of a complex system, which involves multiple parties, such as different groups and prevention and control departments. Thus, it is of practical importance to establish a multi-party game evolution model and study internal laws for curbing an epidemic. This study proposes a method of the combination of the infectious disease warehouse model and evolutionary game. We aim to explore the effects of the prevention and control policies and to have an insight into the influence of social public strategy choices with two-state (susceptible and infected state based on the warehouse model) people. Thus, we construct a tripartite evolutionary game model for two principal groups and the governmental prevention and control department during an epidemic, calculate the replicator dynamics equation and its evolutionary stability value, and conduct a sensitivity analysis of the key parameters. The results show that the governmental prevention and control department’s strategy evolves the fastest. The infected (I) group relates to the loss apportionment ratios α (under efficient prevention and control strategy) and β (under inefficient prevention and control strategy), and the susceptible (S) group is easily influenced by opportunity cost e (average opportunity cost of individuals in Group S with crisis awareness).

Incidence Rate, Pathogens and Economic Burden of Catheter-Related Bloodstream Infection: A Single-Center, Retrospective Case-Control Study.

Indwelling central venous catheters (CVCs) can cause catheter related bloodstream infection (CRBSI). CRBSI occurring in intensive care unit (ICU) patients may lead to the worse outcomes and extra medical costs. The present study aimed to assess the incidence and incidence density, pathogens and economic burden of CRBSI in ICU patients. A case-control study was retrospectively carried out in six ICUs of one hospital between July 2013 and June 2018. The Department of Infection Control performed routinely surveillance for CRBSI on these different ICUs. Data of the clinical and microbiological characteristics of patients with CRBSI, the incidence and incidence density of CRBSI in ICUs, the attributable length of stay (LOS), and the costs among patients with CRBSI in ICU were collected and assessed. A total of 82 ICU patients with CRBSI were included into the study. The CRBSI incidence density was 1.27 per 1000 CVC-days in all ICUs, in which the highest was 3.52 per 1000 CVC-days in hematology ICU and the lowest was 0.14 per 1000 CVC-days in SpecialProcurement ICU. The most common pathogen causing CRBSI was Klebsiella pneumoniae (15/82, 16.67%), in which 12 (80%) were carbapenem resistant. Fifty-one patients were successfully matched with control patients. The average costs in the CRBSI group were $ 67,923, which were significantly higher (P < 0.001) than the average costs in the control group. The total average costs attributable to CRBSI were $33, 696. The medical costs of ICU patients were closely related to the incidence of CRBSI. Imperative measures are needed to reduce CRBSI in ICU patients.