Denture-wearing Patients Research Articles

Early Candida colonisation impact on patients and healthcare professionals in an intensive care unit.

Candida spp. is an opportunistic pathogen that causes superficial and invasive infections with nosocomial outbreaks without strict hygiene protocols. Herein, we assessed oral colonisation by Candida spp. in 209 Intensive Care Unit (ICU) patients between July 2021 and April 2022, conducting clinical, epidemiological, and microbiological characterisation of those developing oral or invasive candidiasis. Initial oral swabs were collected within 24 h of admission in the ICU, followed by collections on Days 2, 4, 6 and 8. Swabs from denture-wearing patients, abiotic surfaces, healthcare professionals' hands, and retroauricular regions were also obtained. Recovered yeasts and filamentous fungi were identified using MALDI-TOF MS and morphological characteristics, respectively. Genetic similarity of Candida spp. isolates was evaluated using Amplified fragment length polymorphism (AFLP), and the antifungal susceptibility profile was determined by broth microdilution. In the study, 64.11% of patients were orally colonised by Candida spp. Of these, 80.59% were colonised within the first 24 h. Oral colonisation also occurred on subsequent days: 50%/Day 2, 26.92%/Day 4, and 11.53%/Days 6 and 8. Of the patients, 8.61% had oral candidiasis, mainly pseudomembranous. Among orally colonised patients, 2.23% developed invasive candidiasis. Besides, 89.47% of healthcare professionals evaluated were colonised. MALDI-TOF MS identified different yeast species, and C. albicans (45.34%), C. tropicalis (15.7%), and C. parapsilosis sensu stricto (9.88%) were the most prevalent. AFLP analysis indicated a high genetic correlation (≥97%) between C. parapsilosis sensu stricto isolates from patients and professionals. Three resistant C. albicans isolates were also found. This study reported a diversity of yeast and filamentous fungi species in ICU patients and highlighted early Candida spp. colonisation risks for invasive candidiasis, as well as the potential horizontal transmission in the nosocomial setting, emphasising the need for effective infection control measures.

Longevity of acrylic and cobalt-chromium removable partial dentures–A ten-year retrospective survival analysis of 1246 denture-wearing patients

Objectivesto assess the survival rates of removable partial dentures (RPDs) and identify factors impacting their longevity. Methodselectronic health records were retrieved of patients aged ≥18 who received RPDs between 2010 – 2021 with a follow-up of ≥ three months. Data extracted included demographics, medical history, dental charting, periodontal screening and recording scores, prostheses details and related interventions, including new dentures/denture remakes, and maintenance. Multivariate Mixed-Effect Cox regression was performed to identify potential RPD survival risk factors. Reduced model selection was reached using a backward step-down by comparing the performance of these multivariable models using the ANOVA test. Results1893 RPDs from 1246 patients were included, with a median follow-up of 21.8 months (range from 3 to 131.3 months). Three hundred and twelve patients received a maxillary RPD, 460 received a mandibular RPD, and the remaining 474 patients received both maxillary and mandibular RPDs. Metal-based RPDs had a median survival of 73 months (95%CI: 70 – 82) versus 45 months (95% CI: 37-67) for acrylic ones. Multivariable mixed effects Cox model showed that the lifespans of RPDs were longer amongst patients receiving more maintenance care within three months [Hazards Ratio (HR)=0.89 (0.83, 0.96)] and after three months [HR=0.53 (0.46, 0.61)] of denture delivery, patients wearing both maxillary and mandibular RPDs [HR=0.67 (0.52, 0.87)], and patients receiving metal-based RPDs [HR=0.31 (0.23, 0.42)]. ConclusionsMetal-based dentures, dual arch restoration, and increased maintenance positively impact the survival of RPDs. Clinical significanceAdapting consent and warranty practices is advised to reflect RPD performance variations.

Denture Adhesives: An Overview

Denture adhesives are used for many years by denture wearers. Proper denture don’t need denture adhesives. Denture adhesives provide satisfaction and confident to denture wearing patients. It reduces the inadequate errors during clinical and technical procedure. Proper application and usage of denture help in proper retention and stability and improve the self-confidence of the patient. There are many advantages and disadvantages are present, Patient should use under the guideline and caution of the dentist. Keywords: Denture adhesives, denture wearing patients, satisfaction and confident

Evaluation of different taste sensations along with body mass index (BMI) in geriatric patients with and without complete dentures.

The purpose of this study was to investigate the effect of acrylic full removable dentures on the perception of four primary tastes (sweet, sour, salty, and bitter), as well as to determine if there is a correlation between changes in body mass index (BMI) and taste perception. A total of 60 patients who wore acrylic removable dentures and 60 controls were included in the study as a convenient sample. Sixteen solutions for basic tastes were prepared, and the patients were asked to identify the taste of each solution from the lowest concentration. Anthropometric measures, such as height and weight, were measured and recorded in an MS-Excel sheet. The data were analyzed using SPSS version 23. The results showed that patients with complete removable dentures had lower taste scores for sourness (P < 0.001) and sweetness (P < 0.001) compared to the control group. However, there was no significant difference in salt taste scores (P = 0.218) and bitterness (P = 0.002) between the two groups. Additionally, the study found a correlation between lower BMI values and higher taste scores among denture-wearing patients, indicating an inverse relationship between total taste scores and BMI. The study suggests that geriatric patients with complete dentures have reduced taste sensations compared to those without dentures which can have a negative impact on their nutritional status. Therefore, it is crucial to provide adequate nutritional support and dietary counseling for geriatric patients based on health policy to maintain their overall health and well-being.

Denture hygiene habit and denture care practice in complete denture wearing patients visiting a dental college

Introduction: After wearing a complete denture, the patient most care for his/her denture and most maintain a good hygiene habit for long term use of the prosthesis. Even after giving denture care instructions at the denture delivery appointment many patients may not fully understand the instructions. This study was performed to assess the denture hygiene habit and denture care procedure being undertaken by complete denture patients coming for treatment in a private dental college.&#x0D; Methods: A descriptive cross-sectional study was conducted among 140 complete denture wearing patients visiting Department of Prosthodontics, Chitwan Medical College from Sep 2021 to Mar 2022. A questionnaire was prepared and used to collect data which included various questions regarding denture hygiene and denture care being undertaken by patients. Descriptive statistical analysis (frequency and percentage) was performed on the data collected by using SPSS Statistical Software Package (version 21.0).&#x0D; Results : A total of 140 responses were included in this study. Out of the patients who responded 52.85% (N=74) were wearing the same denture for less than 5 yrs while 27.85% (N=39) were wearing the denture for more than 5 yrs. Most of them i.e., 73.5% were removing the prosthesis at night time and 61.4% were keeping the denture inside water when removing at night. Out of the participants, 81.42% were cleaning the prosthesis outside of mouth while 18.5% were cleaning the denture both inside and outside of the mouth. All of them were using a toothbrush to clean the denture. More than half (52.14%) of the participants didn’t know for how long they should use complete denture.&#x0D; Conclusion: From the responses obtained in this study it can be concluded that the complete denture wearing patients visiting Chitwan Medical College have fair denture hygiene habits as well as fair knowledge on denture care practice.

Assessment of oral health problems and oral hygiene practices among palliative care patients using a new tool: A pilot study

Introduction: This research paper is a cross-sectional study that aims to estimate the prevalence of oral health problems among adult patients in palliative care, as well as to investigate the oral hygiene practices of palliative care patients in Brunei Darussalam. Patients and methods: In this study, the Oral Palliative Care and Assessment and Referral tool (OPCAR) along with a 15-item questionnaire were utilized as reliable tools for measurements. All palliative care patients who had been assessed in this study were invited to participate. A total of 90 palliative care patients were invited to participate and 73 patient data were used for the subsequent data analysis. Results: The three most common problems among palliative care patients were saliva, lips, and teeth category. Fisher’s exact test identified there were significantly higher teeth-related problems (teeth caries, fracture, broken root stumps) in non-denture wearing patients as compared with denture wearing patients. However, other associations between denture wearing to oral hygiene was of little significance. Conclusions: Using the normal approximation sample method, it was revealed that almost all the participants were eligible to be referred to the dental clinic for at least one oral problem.

Comprehensive assessment of attitude towards denture hygiene habits in complete denture wearers

Background and Aim: With the advanced innovations in the rehabilitation techniques, the usages of removable denture have been reduced significantly. However; complete denture are one of the most common and trendy avenue for restoring completely edentulous situations. The ultimate aim of this study was to assess the denture hygiene attitude in complete denture patients. Materials and Methods: A total of 100 complete denture wearing patients were selected for this assessment. The patients were selected in the age range of 45-70 years. The methodologies were explained to the patients prior to the real execution of the study. All interested complete denture patients were included in the study. We also performed a small demographic recording of the patients that includes data on gender, age, length of prosthesis utilize, cleaning strategies and materials, and so on. Statistical Analysis and Results: Basic statistical analysis was completed using SPSS statistical package for the Social Sciences version 21 for Windows. Only 58% of the patients reported that they use to clean their dentures every day once. Approximately 68% of the patients agreed that they do not remember the verbal and written instructions for denture hygiene at the time of delivery of complete dentures by the dentists.

Dentures for dental therapists - A knowledge update. An awareness of removable prostheses and their impact on the oral tissues

The provision and maintenance of removable prostheses, namely partial and complete dentures, falls within the scope of practice of a general dental practitioner (GDP). This typically involves restoring form and/or function in edentate (toothless) or partially-dentate patients. Dental therapists (DTs) are likely to treat these denture-wearing patients on both a dentist's prescription and via direct access. Having a basic knowledge of the denture-making process, common complications and presentations of the denture-wearer, in terms of the hard and soft tissues, is valuable in ensuring appropriate follow-up with a GDP is made if required. Relevant to DTs in practice, the reader should appreciate how their approach to soft tissues examination, caries management, non-surgical periodontal therapy and prevention, note-keeping and/or clinical photography can be modified and used in the denture-wearing patient, all the while working within their scope of practice, skills set confidence and competencies.

Denture–Mucosa Pressure Distribution and Pressure–Pain Threshold in In Vivo, In Vitro and In Silico Studies: A Literature Review

Aims. The purpose of this systematic review was to evaluate studies that assessed denture–mucosa pressure distribution and pressure–pain threshold and their methodology, used to measure such pressure distributions, mainly in complete and implant overdentures. Materials and methods. An electronic search of the relevant full-text peer-reviewed literature on denture–mucosa pressure distribution was done. Searches were performed independently by two researchers by using the OVID Medline, PubMed and Web of Science databases from 1 January 1946 to 31 December 2021 using the following MeSH terms; (denture OR complete dentures OR implant supported dentures) AND (mucosa OR mucous membrane) AND (pressure OR hydrostatic pressure). Only those publications in the English language were included. Furthermore, a manual search of the citations of the included studies was done to ensure a thorough search was conducted. Results. A full text review resulted in a total of eighteen studies. Of these, seven evaluated various intraoral pressures, two investigated the pressure–pain threshold in edentulous oral mucosa, five measured intraoral pressure through finite element analysis/FEA studies, two demonstrated pressure transducer and pressure measuring systems, and two investigated the comparison between implant-overdentures and complete dentures. Conclusions. To date, there is no study that assesses the pressure distribution on oral mucosa to provide a standardised and validated baseline pressure range which can be used to improve the designs and materials used for fabricating complete dentures. The relationship between pressure on the oral mucosa and the pain threshold of denture-wearing patients still remains poorly understood. There is yet no baseline data which can be universally applied for future studies; to correlate the oral mucosa pressure and pain threshold of edentulous patients encourages further research, especially comparing mucosa pressure under different denture designs for both complete and implant overdentures.

Evaluating impact of removable acrylic dentures on oral health related quality of life (OHRQoL) of patients

Objective: To manage patient expectation and provision of relief, it is vital to assess the impact of different domains of oral health associated with denture wearing which affect OHRQoL. Hence, study aimed to evaluate impact of removable acrylic dentures on OHRQoL of patients and assess influence of sociodemographic variables on OHRQoL. Methods and Material: A cross-sectional study with purposive sampling strategy was used to collect data from denture wearing patients presenting in prosthodontics department of dental teaching hospital of Lahore. A translated version of OHIP-14 (Oral Health Impact Profile) was employed. Mann-Whitney test was used to find association between variables (gender, age, missing teeth, type of denture, denture wearing time) and OHIP-14 items. ANOVA and T-test was performed to evaluate associate between OHIP-14 domain mean and variables. Results: 206 patients were included in the study. OHIP prevalence was 61.2%, whereas OHIP Score was 19.17 ± 10.1. Most affected domain was psychological discomfort (mean=1.81) followed by physical pain (1.76) and functional limitation (1.52). Significant association was observed amongst gender with female more likely to have an impact on OHRQoL due to physical disability, functional limitation and physical handicap. Patients with complete dentures were more likely to experience an impact on their OHRQoL due to physical disability and physical pain (p=0.04, 0.04) Conclusions: OHRQoL was satisfactory in our study however, majority of patients experienced problems associated with denture wearing. Most patients experienced psychological discomfort, physical pain and functional limitation. Female gender and patients with more than 5 missing teeth were more likely to have low OHRQoL. Keywords: Oral health, quality of life, dentures

Oral health-related quality of life in patients infected with HIV, Iran: a cross-sectional study

BackgroundThe life expectancy of patients with Human Immunodeficiency Virus (HIV) has increased, but its oral manifestations can affect the Oral Health-Related Quality of Life (OHRQoL) of these patients. This study aimed to evaluate OHRQoL in HIV-infected patients and determine its related factors.MethodsIn this cross-sectional study, 250 HIV-infected patients were randomly selected from Shiraz Voluntary Counseling and Testing center in 2019. OHRQoL was measured using the revised Geriatric Oral Health Assessment Index for HIV patients. The associations between patients’ OHRQoL and demographic characteristics were examined.ResultsThe mean score of the patients' OHRQoL was 24.55 ± 6.27. The lowest and highest scores belonged to the psychosocial and pain categories, respectively. In the univariate analysis, the OHRQoL was significantly associated with patients' age (p = 0.012), duration of the disease (p = 0.009), job (p = 0.006), edentulous status (p = 0.003), and wearing denture (p < 0.001). However, in the multiple linear regression analysis, a significant difference was found only between denture wearing and non-denture wearing patients (p ≤ 0.001).ConclusionsThe OHRQoL of HIV-infected patients was not optimal since most of the patients were worried about their oral and dental health problems. The OHRQoL was significantly better in denture-wearing patients. This finding highlights the impact of unmet dental needs on OHRQoL in HIV-infected patients. Therefore, dental services coverage for patients with HIV is essential, so that they can have timely access to oral health care. Furthermore, dentures should be considered as an unmet healthcare need among HIV patients in public health policies.

Chronic Hyperplastic and Erythematous Candidiasis Induced by Ill-fitting Complete Denture: A Case Report

ABSTRACT Oral candidiasis is one of the common fungal infections, affecting the various parts of oral mucosa which is caused by Candida albicans. The pathogenicity of Candida is facilitated by many virulence factors, some of which are those for an observance to host tissues and medical devices and secretion of hydrolytic enzymes. Valuation of predisposing factors plays an important role in the treatment of candidal infection. Carefully recording medical history plays a vital role. Topical antifungal application is suggested as a first-line treatment for simple oral candidiasis. Especially in denture wearing patients, it is a common inflammatory reaction, multifactorial etiology, which is usually accompanying by Candida species, particularly C. albicans, because of its high virulence, the capability to adhere and form biofilms on oral cavity mucosa and denture surfaces. This article intensifies the management of oral candidiasis associated with ill-fitting denture commonly encountered in day-to-day dental practice. How to cite this article: Debbarma S, Jamdade A, Yadav S, et al. Chronic Hyperplastic and Erythematous Candidiasis Induced by Ill-fitting Complete Denture: A Case Report. J Mahatma Gandhi Univ Med Sci Tech 2020;5(1):31–33.

Palatal Inflammation and the Presence of Candida in Denture-Wearing Patients.

ABSTRACTAim:Denture stomatitis (DS) is a common inflammatory reaction in denture wearers. The severity of palatal inflammation in DS is believed to be related to Candida colonization. The present study evaluated the presence of Candida at the palatal and the denture surface. The factors associated with DS were also investigated.Materials and Methods:Eighty-two denture wearers were evaluated for DS based on Newton’s classification. The samples were collected from palatal mucosa and the denture surface for Candida culture. The predisposing factors associated with DS were also assessed by questionnaire and by oral and dental prosthesis examination.Results:Thirty patients showed no signs of DS (36.59%), while 52 patients (63.41%) had DS. Candida was detected in 81.71% of all patients and specifically in 26.83% and 54.88% of non-DS and DS patients, respectively. The proportion of patients with a large amount of Candida at the palatal mucosa in the DS group (40.38%) was higher than in the non-DS group (26.67%) but not significantly different (P > 0.05). The amounts of Candida among the different Newton types also showed no statistically significant differences (P > 0.05). Candida was also detected on the denture surface of the non-DS (34.15%) and DS patients (57.32%). The amounts of Candida on the denture surface between the two groups showed no statistically significant difference (P > 0.05). The predisposing factors related to DS included the absence of occlusal rest and poor denture stability (P < 0.05).Conclusions:In this study, no association between the amount of Candida and DS was found. Mycological examination may be useful for the detection of Candida-induced DS and management. However, further study is required to establish a protocol for antifungal drugs prescription in the treatment of Candida-induced DS among the Newton type.

Sağlıklı Bireylerden ve Candida – İlişkili Protez Stomatitili Hastalardan İzole Edilmiş Stok C.albicans Suşları Arasındaki C.dubliniensis Prevalansının Moleküler Yöntemlerle Retrospektif Olarak Araştırılması

Objectives: Candida-related denture stomatitis (C-RDS), is the most frequent form of oral candidiasis, being detected in approximately 50%-65% of denture-wearing patients. Candida albicans has been shown to be the principal species responsible for inflammatory pathology. Candida dubliniensis, first described in Dublin in 1995, was found to be very similar to C. albicans in terms of phenotypic features and the type of lesion it causes. It was necessary to determine the historical prevalence of C.dubliniensis due to the possibility that the strains identified as C.albicans in the past years were C.dubliniensis. Materials and Methods: In this study, 81 yeast strains isolated from oral samples and identified as C.albicans only by photypic methods and kept in the stock collection until 2003 were re-examined by molecular methods. Results: In the genotypic examination performed by polymerase chain reaction and restriction endonuclease reactions, 4 (8.8%) of 45 C.albicans strains isolated from healthy individuals were found to be C.dubliniensis, but all 36 strains isolated from patients with C-RDS were C.albicans. Conclusions: As a result of this retrospective study, it was found that the prevalence of C.dubliniensis among 81 yeast strains isolated orally was 4.9%, but it was not effective in the pathogenesis of C-RDS.

Frequency Of Neck Disability Among Patients Wearing Complete Dentures

BACKGROUND: Temporomandibular disorder (TMD) is a collective terminology embracing a number of medical issues, which involve the masticatory musculature, the temporomandibular joint or both. Complete denture wearing most often not only effects TMJ but also effects the neck and its functionality.&#x0D; OBJECTIVETo assess the frequency and level of Neck disability among patients wearing complete dentures.&#x0D; METHODSIn this study a total of 100 complete denture wearing patients participated. Patients with any previous maxillofacial injury, trauma and below the age of 40 were excluded. Simple convenient sampling was used to collect all the data. Results: A total of 100 complete denture wearing patients participated in this study. The study included 50(50%) male and 50(50%) female with and average mean age of 57.68.&#x0D; RESULTResults showed 11(11%) experienced moderate recurring pain at neck movement, 10(10%) needed help every day in most aspects of self-care, 6(6%) patients wearing full dentures suffered from moderate neck pain or disability.&#x0D; CONCLUSIONThe study concluded that frequency and level of Neck Pain was variable among patients wearing complete dentures. Many of the full denture wearing patients experienced more than one clinical symptoms of Neck Disability.

Etiology and Management of Inflammatory Papillary Hyperplasia in Completely Edentulous Patients - A Review

Oral mucosa of complete denture wearing patients is subjected to varying amount of stresses as compared to patient having natural teeth. This can leads to different type of oral mucosal lesions like denture stomatitis, epulis fissuratum, angular cheilitis, traumatic ulcers, inflammatory papillary hyperplasia (IPH) etc. IPH is a type of chronic inflammatory proliferative lesion characterized by numerous small, wart like edematous red papillary growth most commonly seen in deepest part of the palate. Review of literature suggest denture associated widely distributed etiology for IPH like over accentuation of palatal relief and vacuum chamber in upper denture, old ill fitting dentures, poor denture hygiene, continuous denture wearing habit, faulty occlusion, skidding of instable denture etc. Treatment for IPH varies with the severity of the condition and may range from conservative to surgical depending on clinical presentation. Conservative approach include discontinuing use of ill fitting denture, correction of faulty prostheses, improving the oral and denture hygiene and antifungal drugs. However, the surgical approach is used when the lesion is more aggressive and this include supraperiosteal excision, resesctive surgery, cryotherapy, and electrosurgery, blade-loop surgery, fulguration, and mucoabrasion or laser surgery. As a method of prevention patient should be advised to avoid continuous day and night wearing of denture. Additionally, avoid providing excessive relief in the palatal region, as these areas become site for bacterial and fungal colonization. Patients should be well motivated for proper care and maintenance of denture hygiene and also for the importance of periodic dental visits and follow-ups.

Effect of &lt;i&gt;Phyllanthus amarus&lt;/i&gt; Coating Denture Resin on Candida Adhesion and its Effect on Human Gingival Fibroblast

Candida infection has become increasingly important as an opportunistic infection frequently found in the oral cavity of denture wearing patients. The infection develops on oral mucous membrane and can spread to other parts of the body. Phyllanthusamarus, extensively grown in many tropical and subtropical countries, has been reported to have various medicinal properties including antimicrobial activity. This study aimed to assess the effect of P.amarus coating denture resin on Candida adhesion and its effect on human gingival fibroblast. The P. amarus coating solution was prepared by water extraction of dried leaves and freeze drying. Denture PMMA resin (SCG Chemical, Thailand) samples were made and coated with various concentrations (0.01-10 mg/mL) of P. amarus solution. Candida adhesion assay was performed on C. albicans ATCC 10231, C. glabrata ATCC 6258, C. krusei ATCC 90030 and C. tropicalis ATCC 13803 based on the method described by Samaranayake and MacFarlane. Cytotoxicity test was done on human gingival fibroblasts (HGF) according to ISO standard 10993-5/2009 for medical product testing. The result showed that P.amarus coating denture resin exhibited an inhibitory effect on the adhesion of all species of test Candida. Cytotoxicity testing revealed a dose-dependent effect of the P. amarus extract on human gingival fibroblast. At the concentrations of 0.1, 1, 5 and 10 mg/mL, the extract produced 84.7%, 73.4%, 64.7% and 38.2% of cell viability, respectively. In conclusion, coating denture resin with P. amarus at a concentration of 1 mg/mL can be used safely as a natural alternative preventive to control or prevent Candida infection caused by C. krusei and C. tropicalis in denture-wearing patients avoiding side effects of chemical antifungal agents. Further studies are needed to define the antifungal components and mechanisms of action as well as clinical trials in the patients.

Evaluation of Oral Dysfunction in Completely Edentulous Denture Wearing Patients

Background: Oral dysfunction is the difficulties faced by the complete denture wearers during speech mastication, pain and esthetics. By knowing this oral dysfunction we can make a satisfactory complete denture to the patient. Aim: The aim of the study is to evaluate oral dysfunction in complete denture wearers using a Clinical Dysfunction Index. Materials and Methods: Potential study participants were interviewed regarding their satisfaction with their complete denture after minimum three months of denture wear. The first twenty satisfied and unsatisfied complete denture wearers were recruited for the study. The data collection was done using a questionnaire and clinical examination was carried out to ascertain the quality of the denture based on stability, occlusion, articulation, oral mucosa and resilience. Clinical Dysfunction Index by Helkimo [1974] was used to assess the functional health of the Temporo-Mandibular joint. Results: According to the results of our study fewer participants reported difficulty in chewing among those with correct articulation, correct occlusion and good retention of their dentures and more participants reported difficulty in chewing with dentures having incorrect articulation, incorrect occlusion and minimum retention Conclusion: Knowledge about oral dysfunction in complete denture wearers can motivate us to pay careful attention to factors that may influence the satisfaction of complete denture wearers as observed from this study.

THE STUDY OF ETIOLOGICAL FACTORS ASSOCIATED WITH DENTURE STOMATITIS IN AN INDIAN POPULATION

Aim: The aim of this study is to find out the possible etiological factors for denture stomatitis (DS) in completely edentulous denture wearing patients by cross-sectional study. Material and Methods: Population for this cross-sectional study consisted of 60 completely edentulous denture wearing patients residing in Ahmedabad, India. Data collection was done by questionnaire, oral examination and denture evaluation. All the data were analyzed using the software SPSS. Qualitative data were analyzed by Chi-square test and quantative data were analyzed by student t test. Results: This study showed 28% prevalence of denture stomatitis (17 out of 60 examined patients) in this study population. Many factors can be associated with DS, but present study showed significant correlation between Continuous denture wearing, Age of denture, Denture hygiene, Candidiasis, Lack of denture stability, Decrease VDO, High sugar intake, Hypo salivation, Low salivary pH. Conclusion: Apart from infection, particularly with C.albicans, denture related factors can also cause denture stomatitis and these prosthetic factors appear to play mainly a traumatic role in the occurrence of DS. Patient should be motivated to practice proper denture wearing habits and maintenance of oral hygiene and follow a program of recall and maintenance for continuous monitoring of dentures and oral tissues. Keywords: Denture stomatitis, Denture hygiene, Retention, Stability, Vertical dimension.

Prevalence of Oral Mucosal Lesions in Patients with Hematological Disorders or Cancer: A Cross-sectional Study

Background: Oral cavity, as the main source of complications such as infection, is unfortunately ignored in cancer patients. In this study, the frequency, type, and location of oral mucosal lesions were determined among patients admitted in the hematology and oncology department. Methods: In this cross-sectional study, 88 admitted patients were examined between November 20, 2017 to August 21, 2018. Demographic data, history of smoking, and denture use were documented. Oral examinations were further conducted to evaluate oral soft tissue lesions according to the checklist. Results: 88 hospitalized patients were screened, out of whom 57(64.7%) had at least one lesion. A total of 79 oral mucosal lesions were identified and ulcerative lesions, found in 51 (57.9%) patients, were among the most frequently encountered problems. Pigmented lesions were more prevalent in smokers (P<0.001). Red and white lesions were significantly more than other lesions among complete denture wearing patients. Conclusion: In light of the high prevalence of oral complications in our patients, this study indicates the need for consultation with oral medicine specialist for a timely diagnosis and better management during the treatment process.