Biodentine is a tricalcium silicate-based cement designed for permanent dentin replacement material and has drawn attention in recent years. Biodentine has been adviced to be used in various clinical applications such as pulp caping, apexification,root perforations, retrograde fillings and dentine replacement. There has been considerable research performed on this material since its launching however, there is scarce number of review articles that collates information and data obtained from these studies. Therefore, this review article was prepared for providing a general picture regarding the characteristics of the material. Biodentine is a good biocompatible and bioactive material. It helps in the protection of underlying pulp by inducing tertiary dentin formation. Unlike other dentin substitutes, Biodentine application does not require any conditioning of the dentin surface. The restoration sealing of Biodentine is micromechanical retention by penetrating into the dentin tubules forming tag-like structures. After its setting, Biodentine can be reshaped like natural dentin. Published clinical trials, histology of human teeth and clinical cases show that Biodentine has a wide spectrum of clinical applications as a permanent bulk dentin substitute in pediatric dentistry and restorative dentistry as a possible replacement material.