Dental Health Of Patients Research Articles

Examination of the Knowledge Levels of Family Medicine Residents in Turkey about Oral and Dental Health.

To measure the general oral and dental health knowledge level of family medicine residents who are receiving full-time specialty training in Turkey. Primary care physicians can contribute to improving the oral and dental health of patients during general health services. The fundamentals of oral and dental health that the family medicine physicians should know about were determined, and questionnaire items on these fundamentals were prepared. The sample size was calculated as 296 individuals. The survey was conducted online. The collected data were analysed employing the following tests: chi-squared, Fisher, Kolmogorov-Smirnov, Spearman, ANOVA, Mann-Whitney U, Kruskal-Wallis, and Bonferroni. 302 family medicine residents in various clinics in Turkey participated in the study. The mean age of the participants was 29.6 ± 5.1. The mean knowledge scores of the resident physicians were calculated as 65.2 ± 10.9 (lowest: 27; highest: 92). The majority of resident physicians stated that they did not receive training on oral and dental health during their residency training, and that they agreed with the idea of integrating it into the residency training curriculum. The general knowledge level of family medicine residents in Turkey about oral and dental health was found to be moderate.

Influence of factors of systemic inflammation and endothelial dysfunction in somatic pathologies on the success of dental implantation (literature review)

In the presented literature review, the issue of the influence of general somatic factors associated with diseases of the cardiovascular and endocrine systems on the success of dental implantation was studied. The issues of the relationship of systemic inflammatory processes and periodontal status with the dental health of patients with background pathologies associated with an imbalance of pro- and anti-inflammatory cytokines, insulin and glucose in the blood in diabetes mellitus and obesity, factors of endothelial dysfunction in atherosclerosis, hypertension and coronary heart disease are highlighted. Based on the analyzed information, it was confirmed that poor-quality history taking, the lack of a thorough diagnostic examination (biochemical blood test, coagulogram, reaction to the presence of specific infections and viral diseases), ignoring the need to correct existing local and systemic inflammatory phenomena before dental implantation can lead to a violation the process of osseointegration, the occurrence of peri-implantitis, implant rejection reactions. In this regard, it can be concluded that when planning complex dental treatment, attention should be paid not only to local dental symptoms, but also to the general history and laboratory data, which will improve the quality of dental implantation.

Oral Microbiome and Multiple Sclerosis? A Novel Concept!

Human oral microbiota refers to the significant number of microorganisms that exist in the human mouth. It is one of the most intricate microbial populations in the human body. Recent studies have suggested the role of the oral microbiome in diverse nervous system diseases. Consequently, investigating the impact of the oral microbiome in patients with Multiple Sclerosis (MS) could reveal potential associations with the disease. In this review, the role of oral microbiota in MS patients has been addressed. The findings of this study hold promise for future approaches to oral and dental health in patients with Multiple Sclerosis. Also, In the future, oral microbiota may become a new target for uncovering novel approaches to prevent and/or treat MS.

Abstract 17580: "Healthy Smile for a Healthy Heart": A National Study on the Correlation Between Periodontal Diseases and Coronary Artery Disease

Introduction: Chronic inflammatory periodontal disease (CIPD) is a common disease of the supporting tissues of the teeth that manifest as swelling, bleeding, pain, and clinical attachment loss (CAL) upon periodontal examination. CIPD has been associated with a chronic inflammatory state, also a known risk factor for coronary artery disease (CAD). Hypothesis: There is a possible correlation between CIPD and CAD. Methods: We utilized the 2013-2014 National Health and Nutrition Examination Survey database. We included participants aged 30 years and above who reported having gum disease and had undergone a periodontal examination. CAL measured in millimeters, was reported at six different locations around 28 teeth. To obtain national estimates, we conducted complex survey sample analyses, accounting for weights, clustering, and strata. Furthermore, we adjusted for well-known CAD risk factors in multivariate analyses. Results: Our study included 184,010,722 participants; 7.3% had CAD (n=13,461,796), and 17.1% reported CIPD (n=31,425,382). Baseline Characteristics are presented in Table 1. The unadjusted rate of CAD was higher in patients with CIPD than those without CIPD [10.3% (n=3,238,995) vs 6.7% (n=10,222,801), p=0.018]. Similarly, average CAL was higher in patients with CAD (2.04 vs 1.62 mm, p<0.001). After adjusting for confounders listed in Table 1, CIPD was a significant predictor of CAD (OR 1.744, 95% CI 1.088-2.796, p=0.012). The average CAL of all the teeth also predicted CAD (OR 1.195, 95% CI 1.025-1.394, p=0.026). Conclusions: Our data suggest that patients with reported CIPD had a 1.7 times higher risk of developing CAD. Similarly, each 1 mm increase in CAL leads to a 20% increased CAD risk (OR 1.2). Further prospective studies are needed to confirm these findings and to explore whether treatment of CIPD mitigates the increased CAD risk. These findings underscore the significance of optimizing dental health in patients with CAD.

Dental health of patients using antidepressants and methamphetamines

The search was performed in the PubMed database, and the results of own research on the effects of antidepressants on dental health were presented. Literature data on the impact of methamphetamine use on dental health are also provided. Selective serotonin reuptake inhibitors have been shown to cause bru-xism, which can exacerbate temporomandibular joint disorder, and tricyclic antidepressants (especially low-dose amitriptyline) can reduce the risk of bruxism caused by another antidepressant. Antidepressants, mostly tricyclic, cause xerostomia, leading to the salivary hypofunction. Similar effects such as bruxism and xerostomia are also noted when using methamphetamines. Saliva contains a high concentration of calcium and phosphate ions, which serve as raw materials for the remineralization process, it also buffers organic acids formed by dental plaque, thereby preventing periodontitis and caries. Xerostomia due to the use of antidepressants or methamphetamines causes taste disorders, the appearance of bad breath, mouth ulcers, impairs the processes of chewing, swallowing and speech, changes the microbial colonization of the oral cavity, causing the development of dental ca-ries, candidiasis, atrophy of the mucous membrane and a burning sensation, difficulties in keeping dentures, negatively affects the quality of life of patients. Therefore, it is important for dentists to be aware of the oral problems associated with the use of methamphetamines and antidepressants, identify them early, and not only provide topical treatment, but also discuss with patients the risks associated with their lifestyle or treatment.

Assessment of dental health in patients requiring general anesthesia – An observational study

ABSTRACT Introduction: Anesthesiologists frequently work with the oral cavity, but may lack in-depth knowledge of oral health, including anatomy, symptoms, and dental prostheses. Materials and Methods: An oral health questionnaire was developed for preanesthesia checkups to facilitate the process. A prospective observational study was conducted over a period of 18 months, which included 200 patients of different genders, aged 10 years or older, and with a physical status ranging from ASA 1 to ASA 3, who were scheduled for elective surgery. The data was collected, compiled, and analyzed using Epi Info (version 7.2). Results: The study included subjects with a mean age of 41.65 ± 11.85 years, with most falling in the age range of 40-50 years. Of all the participants, around 58% were male. The study discovered a significant relationship between addiction habits and oral health problems such as bad breath, missing teeth, gum bleeding or pain on chewing, and loose teeth. It was found that those who used pan and tobacco had visited a dentist the most. Additionally, the use of certain drugs was associated with gum bleeding, pain on chewing, and loose teeth. Patients with systemic diseases such as diabetes mellitus, cancer, and liver diseases also reported poor oral health. Conclusion: The study revealed that the Indian population tends to visit dentists only when experiencing pain or seeking treatment rather than for preventive care.

Dental health in patients with and without HPV-positive oropharyngeal and tongue cancer.

BackgroundHuman papilloma virus is associated with oral and oropharyngeal cancer. Our aim was to examine oral health in patients with oropharyngeal (OPSCC) and oral tongue cancer (OTSCC), expecting better oral health among OPSCC patients.Material and methodsFifty-five OPSCC patients with known HPV status and 59 OTSCC patients were randomly selected from a list of consecutive patients of the Helsinki University Hospital, Finland. Oral health was assessed from panoramic jaw radiographs. Total Dental Index (TDI) summarizing the dental health status was calculated and Finnish population study data were used for comparison. Descriptive statistics were used for analyses.ResultsPatients with HPV-positive OPSCC had higher periapical lesion index compared with HPV-negative OPSCC patients or with OTSCC patients. Residual roots were more common among OPSCC patients compared with OTSCC patients, because of their higher occurrence among HPV-negative OPSCC patients compared with OTSCC patients. Similarly, modified TDI score was significantly higher among OPSCC patients than among OTSCC patients, because of higher TDI score among HPV-negative OPSCC patients compared with OTSCC patients. OPSCC patients more often used a removable prosthesis than OTSCC patients. Dental health of the cancer patients was poorer when compared with the population data.ConclusionsOur study hypothesis was only partly confirmed. Periapical lesions were more prevalent among HPV-positive OPSCC patients, compared with the other groups. The number of residual roots was higher among HPV-negative subgroup. Thus, OPSCC patients had worse oral health parameters than OTSCC patients.

The Effect of Zingiber, Alpinia Officinarum with Periodontal Therapy on Clinical Outcome and Oxidative Stress

Many popular mouthwashes containing herbal products have helped to control dental plaque and gingivitis; however, they are used for a short time and only as an adjunct to other oral hygiene measures such as brushing and flossing. Recently, herbs such as Zingiber ginger and Alpinia officinarum, with antioxidant, antifungal, anti-inflammatory, and antibacterial properties apart from being cheap and safe, have been used as plant extracts in mouthwashes. The aim of this study was to assess the effect of both herbal mouthwashes and periodontal therapy on oxidative stress, total antioxidant capacity, and antioxidant enzyme activities in the saliva of patients with periodontitis as well as to investigate the association between oxidative stress, antioxidant enzymes, total antioxidant capacity, and periodontal parameters. 72 patients were selected using random sampling and divided into three categories. Each category consisted of 24 patients: the first group received non-surgical periodontal treatment and Zingiber ginger mouthwash, the second group received Alpine officinarum and non-surgical periodontal therapy, while the third control group received non-surgical periodontal therapy only. Periodontal parameters (Clinical Attachment Loss and Plaque Index) were recorded by a calibrated periodontal probe (William probe). Salivary oxidative stress (eight hydroxy deoxyguanosine) was measured by ELISA, and catalase and total antioxidant capacity were measured using a spectrophotometer. The concentration of salivary antioxidants significantly increased, and the periodontal parameter and eight hydroxy deoxyguanosine significantly decreased after two weeks. The p-value in the ginger group was (P < 0.0001). For the alpine officinarum group, the clinical parameters showed a significant decrease, and the p-value was (P < 0.0001). While catalase displayed a significant increase (P < 0.0001), the eight hydroxy deoxyguanosine markers showed a significant decrease (P < 0.02). Zingiber ginger and Alpine officinarum mouthwashes, in addition to periodontal therapy, can be effective in controlling inflammation, reducing oxidative stress, and improving dental health in patients with chronic periodontitis. Mostly positive associations were detected among clinical and biochemical parameters.

Dental health in patients with inflammatory bowel disease and the role of biomarkers in diagnosis

Because the oral cavity is the entrance portal and part of the gastrointestinal tract, oral manifestations occur in patients with inflammatory bowel disease (IBD). Oral manifestations of IBD manifest as a systemic complication or extraintestinal manifestation that may precede, exacerbate, or regress with changes in disease severity. Some of these manifestations are aphthous ulcers, gingivitis, periodontitis, halitosis and others. The oral cavity is one of the most affected areas in patients with CKD - 25-30% of patients. The aim of the present study is to investigate the relationship between dental health and chronic inflammatory bowel disease and the role of biomarkers in their diagnosis. For the period between December 2020 and March 2021 is conducted a systematic analysis of scientific publications in the available databases (PubMed, BioMedCentral, ScienceDirect, Scopus, Web of Science), examining the relationship between dental health and chronic inflammatory bowel disease and the role of biomarkers in their diagnosis.

Association between oral health-related quality of life and general health among dental patients: a cross-sectional study.

SummaryGlobally, the prevalence of chronic diseases is increasing significantly, causing deterioration of oral and general health and therefore quality of life. The present study was designed to assess the relationship between oral health-related quality of life and general health of dental patients. The study is part of the University’s plan to achieve the United Nations Sustainable Development Goals number 1, 3, 4 and 5. Dental school students’ satisfaction with their early engagement in clinical activities and research work was also evaluated. A convenience sample of 600 subjects attending dental clinics aged ≥18 years of both sexes was included in the study. Second-year dental students conducted the study under the supervision of public health staff members over two successive academic years (2015–2016 and 2016–2017). Oral health-related quality of life was assessed using the Dental Impact on Daily Living (DIDL) questionnaire. Blood pressure, random blood glucose level, body mass index, and waist circumference were measured as indicators of general health. There were statistically significant inverse correlations between DIDL scores and both mean blood pressure (r = −0.215, p < 0.001) and mean blood glucose level (r = −0.272, p < 0.001). Non-significant inverse correlations were observed between DIDL scores and both body mass index (r = −0.062, p = 0.131) and waist circumference (r = −0.040, p = 0.340). Students’ satisfaction scores with research activities were high, ranging from 75.9% to 78%. Dentists must raise patients’ awareness about the importance of oral health and its impact on their quality of life and general health. Participation of dental students in dental research is encouraged even in their early academic years.

Association between oral health-related quality of life and general health among dental patients: a cross-sectional study

Abstract Globally, the prevalence of chronic diseases is increasing significantly, causing deterioration of oral and general health and therefore quality of life. The present study was designed to assess the relationship between oral health-related quality of life and general health of dental patients. The study is part of the University’s plan to achieve the United Nations Sustainable Development Goals number 1, 3, 4 and 5. Dental school students’ satisfaction with their early engagement in clinical activities and research work was also evaluated. A convenience sample of 600 subjects attending dental clinics aged ≥18 years of both sexes was included in the study. Second-year dental students conducted the study under supervision of public health staff members over two successive academic years (2015–2016 and 2016–2017). Oral health-related quality of life was assessed using the Dental Impact on Daily Living (DIDL) questionnaire. Blood pressure, random blood glucose level, body mass index, and waist circumference were measured as indicators of general health. There were statistically significant inverse correlations between DIDL scores and both mean blood pressure (r = −0.215, p < 0.001) and mean blood glucose level (r = −0.272, p < 0.001). Non-significant inverse correlations were observed between DIDL scores and both body mass index (r = −0.062, p = 0.131) and waist circumference (r = −0.040, p = 0.340). Students’ satisfaction scores with research activities were high, ranging from 75.9% to 78%. Dentists must raise patients’ awareness about the importance of oral health and its impact on their quality of life and general health. Participation of dental students in dental research is encouraged even in their early academic years.

ИЗУЧЕНИЕ ВСТРЕЧАЕМОСТИ ОСЛОЖНЕНИЙ СТОМАТОЛОГИЧЕСКОГО ОРТОПЕДИЧЕСКОГО ЛЕЧЕНИЯ У ПАЦИЕНТОВ С САХАРНЫМ ДИАБЕТОМ

Subject. An interdisciplinary approach in the science and practice of the dental industry has long become an established reality. The direct and indirect effect of a huge number of somatic diseases on the dental health of patients, the tactics of their treatment and subsequent follow-up observation was studied. One of these diseases is diabetes. On the other hand, the number of lawsuits against orthopedic dentists is growing every year and they are often associated with an insufficient, in the patient's opinion, period of comfortable use of the manufactured construction. When analyzing the causes of patients re-seeking dental orthopedic care, we revealed a significant discrepancy in their occurrence in patients with and without diabetes. In this article, we tried to describe the causes and consequences of such a phenomenon and propose ways to solve the discovered problem.&#x0D; The goal is to reduce the number of complications of dental orthopedic treatment in patients with diabetes mellitus.&#x0D; Methodology. We analyzed data from 304 patients who applied to dental clinics for the purpose of repeated prosthetics of teeth and dentitions. One of the research methods was a specially designed questionnaire, which included a number of questions for the reasons for replacing the prosthesis. Clinical and paraclinical methods for examining patients that meet the standards of care for established diagnoses were also used.&#x0D; Results. A clear dependence of the life of dentures on the presence of a history of diabetes was revealed. The main complaints of patients with repeated visits to the orthopedic dentist are formulated. The most common causes of early abandonment of the use of dentures were identified and the peculiarities of adaptation to them in patients with the pathology under consideration were determined.&#x0D; Findings. The obtained data can be applied in predicting the immediate and long-term results of prosthetics of teeth and dentitions, and on the basis of them, the period of clinical observation of patients with diabetes can be changed.

A randomized controlled trial of an educational intervention to promote oral and dental health of patients with type 2 diabetes mellitus

BackgroundDiabetes is the most prevalent disease resulted from metabolic disorders. This study aimed to investigate the effect of training based on health belief model (HBM) on oral hygiene-related behaviors in patients with type 2 diabetes mellitus.MethodsThis study was conducted as an educational randomized controlled trial (single blind) on 120 patients with type 2 diabetes referring to a diabetes clinic selected through systematic sampling, who were assigned to two groups of control (N = 60) and intervention (N = 60). The data collection tool was a valid and reliable questionnaire based on HBM which was completed by both groups before the intervention. Then, the intervention group received 4 sessions of educational program based on HBM in 1 month, and the same questionnaire was completed again after 3 months and the data were analyzed through SPSS version 20 software with inferential statistics, t-test, paired t-tests, Chi square, Mann-Whitney test, and Wilcoxon test analysis.ResultsThree months after the intervention, awareness of the patients and perceived susceptibility, benefits, self-efficacy, internal cue to action, and performance in oral and dental hygiene-related behaviors had a significant increase in the intervention group (p < 0.05). So that the performance of oral and dental hygiene in the intervention group increased from 2.16 ± 0.71 to 3.25 ± 0.49 (p = 0.001) after the education.ConclusionOur results suggest that training patients with diabetes based on HBM as well as through active follow-up can enhance their skills in oral and dental hygiene-related behaviors. Controlling, monitoring and follow-up during the program are also recommended.Trial registrationIranian Registry of Clinical Trials, IRCT 2017050733847N1. Prospectively registered 14 June 2017, http://en.irct.ir/trial/26011

The analysis of self-evaluation of stomatological health in patients with partial absence of teeth

The aspects related to self-assessment of dental health in patients with partial absence of teeth were analyzed using questionnaire survey, clinical examination of patients and extracting data from health questionnaires from patient's medical records were studied. Patients with a partial absence of teeth most often admit to dental medical organization with complaints about impaired chewing function. At the same time, most of respondents with largest number of such complaints belong to older age groups: 45-54 and 55-62 years. The main problems with maxillofacial region of patients are of aesthetic character - the general aesthetics of the face and smile. As well as main factors of patients' anxiety, significant for dental health self-assessment are facial distortion and unattractive smile. The insufficient knowledge and literacy of studied group of patients regarding their need to restore partial absence of teeth, possible consequences of partial absence of teeth and the lack of information about modern methods of orthodontic care for patients with partial absence of teeth were established. The criterion of following the recommendations of attending physician and regularity of brushing teeth is defined and described. The application of study data makes it possible to optimize organization of orthodontic care for patients with partial absence of teeth.

Attitude toward Dental Health and Treatment in Patients with Medical and Non-Medical Education

The article discusses the differences in attitudes towards dental health among persons with and without medical education. The authors described the criteria for assessing the quality of dental care, the preferred quality of a dentist and causes dental phobia in the adult population, as well as highlighted ways to improve compliance and reduce fear and anxiety before visiting the dentist. A total of 88 apparently healthy respondents who do not pass dental treatment at the time of the study (52 women and 36 men) took part in the study (the average age is 32 ± 12.5 years). The following techniques were used: (1) the survey Attitude to Health by R.A. Berezovskaya for assessing the respondents’ attitude to their own health (emotional, behavioral, cognitive, and valuemotivational scales); (2) the Life Quality Scale by N.E. Vodopianova for the assessment of the general life quality index and the self-assessment of the respondents life quality in such categories as: work, personal achievements, health, communication with relatives, support, optimism, tension, self-control, negative emotions; (3) the questionnaire Attitude to dental health developed for research at the Department of General and Clinical Psychology of Pavlov First Saint Petersburg State Medical University. Key research findings is: (1) most patients prefer an empathic-non-prescriptive type of dentist; (2) for most patients are important professional and communication skills of the dentist; (3) there are differences in attitudes towards dental health in patients with and without medical education.

ДИНАМИКА КАЧЕСТВА ЖИЗНИ БОЛЬНЫХ ХРОНИЧЕСКИМ ГЕНЕРАЛИЗОВАННЫМ ПАРОДОНТИТОМ СРЕДНЕЙ СТЕПЕНИ ТЯЖЕСТИ НА ФОНЕ ТРАДИЦИОННОГО ЛЕЧЕНИЯ

Background. The high prevalence of inflammatory periodontal diseases in young people determines the relevance of the study of the diagnosis and treatment of pathologies. Chronic generalized periodontitis of moderate severity is a General medical and socio-economic problem. Mobility and loss of teeth, the presence of a focus of chronic infection in periodontal pockets, gum recession and bad breath lead to psychological discomfort associated with difficulty in communicating, eating, daily life. Thus, the quality of life of patients due to dental health is an important indicator of the subjective evaluation of the effectiveness of therapeutic measures.&#x0D; Objectives ― study of the dynamics of quality of life in patients with chronic generalized periodontitis on the background of traditional therapy&#x0D; Methods. In the course of the study, the treatment of chronic generalized periodontitis of moderate severity was carried out using the traditional treatment regimen, and the long-term indicators of the quality of life due to dental health were studied on the basis of the OHIP-14-RU questionnaire.&#x0D; Results. As a result of our study revealed a significant improvement in the quality of life due to dental health in patients with chronic generalized periodontitis of moderate severity in the long term. At the same time, after 12 months, some patients in the questionnaires recorded problems in communication, after 6 and 12 months – problems in everyday life.&#x0D; Conclusions. Our study demonstrates an improvement in the quality of life due to dental health in patients with chronic generalized periodontitis of moderate severity against the background of traditional treatment. However, the emergence of problems in communication in the long term after therapy suggests the need to optimize treatment aimed at their elimination.

Evaluation of Oral Findings with Oral and Dental Health in Patients Diagnosed with Psoriasis Vulgaris

Evaluation of Oral Findings with Oral and Dental Health in Patients Diagnosed with Psoriasis Vulgaris

Effective Factors on Oral and Dental Health of Patients with Diabetes Mellitus Type 2 Based on the Health Belief Model

Effective Factors on Oral and Dental Health of Patients with Diabetes Mellitus Type 2 Based on the Health Belief Model

ОПЫТ ПРИМЕНЕНИЯ НОВОЙ ФАРМАКОЛОГИЧЕСКИ АКТИВНОЙ КОМПОЗИЦИИ НАНОСТРУКТУРИРОВАННОГО ФТОРАПАТИТА ПРИ ЛЕЧЕНИИ РАННИХ ПРОЯВЛЕНИЙ ПОВЫШЕННОЙ СТИРАЕМОСТИ ЗУБОВ

Subject. The article presents an investigation of the dental status of patients with early manifestations of tooth wear. The effectiveness of applying a new pharmacologically active composition of nanostructured fluorine hydroxyapatite as a remineralizing agent in the form of a gel in comparison with traditional methods was evaluated. Objectives. To study the effectiveness of a new pharmacologically active composition of nanostructured fluorhydroxyapatite application in the treatment of early manifestations of tooth wear. Methods. 153 patients were examined at the stages of remineralizing therapy with using a new pharmacologically active composition and traditional methods, indexed OHI-S, PMA, KPU, periodontal index, indicators of electrometry, test of enamel resistance, quality of life. Results. Within 1 year of observations in the study groups, in 91.2% cases, a persistent remission of the disease without progression of the loss of hard dental tissues was observed against the background of a decrease in the electrometry and test of enamel resistance test. 56.4% of patients throughout the year noted the absence of a symptom of hyperesthesia. The recurrence of the symptom of hyperesthesia against a background of fixed indices of resistance and electrical conductivity of enamel was noted by 34.8% of patients. In 8,8% of cases there was a lack of dynamics of indices and reduction of hyperesthesia. Conclusions. The level of caries-resistance and electrical conductivity of enamel of the teeth of patients of two groups was studied: with facets of erasability within the enamel and with dotted dentin damage against the background of the course of remineralizing therapy with using pharmacologically active composition of nanostructured fluorine hydroxyapatite. The relationship between the reduction of the symptom of hyperesthesia and the increase in the level of dental health of patients after the end of treatment was revealed.

Comparative evaluation of oral and dento-maxillofacial manifestation of patients with sickle cell diseases and beta thalassemia major

ABSTRACTBackground: Regarding the importance of oral and dental health in patients with hemoglobinopathies and also due to the different results of different studies in this background, in patients with beta thalassemia (BTM) and sickle cell disease (SCD), this study aimed to evaluate and compare the oral and dental manifestations of patients with BTM and SCD.Material and methods: In this cross-sectional study during the years 2014–2017, a total of 175 patients (with documented BTM or SCD attending to Tehran, Mashhad, Isfahan, and Tabriz cities central hospitals) were randomly recruited. Required information was gathered through a thorough physical examination of the oral cavity in a private office and a face-to-face interview by an orthodontist and two dentists. Data were analyzed using SPSS version 22.0.Results: In general, 120 diagnosed patients with BTM (88 males and 32 females) and 55 patients with SCD (25 males and 30 females) attending to Iran largest cities, central hospitals were randomly recruited. We found a significantly higher prevalence (p < .05) of some oral manifestations among the BTM patients (Gingival Index = 2.18 ± 1.300, 1.64 ± 0.963; Decayed teeth = 8.31 ± 3.330, 2.33 ± 1.221; Missing teeth = 3.51 ± 2.016, 1.19 ± 0.820; DMFT = 13.92 ± 7.001, 2.63 ± 1.301) than the apparently healthy people.Conclusion: Finally, the study gives an insight into the various oral and dento-maxillofacial manifestations of SCD and BTM and also reveals an association that exists between the oral and dento-maxillofacial manifestations and systemic health in these patients, thus stressing the importance of the concise and periodic examination of these individuals to perform appropriate preventive dental and periodontal care, and the facilitation of the management of the disease.