Objective: To assess the knowledge and attitudes of Turkish dental patients about COVID-19 infection. Material and Methods: Four hundred fifteen patients who received an oral and dental health center were interviewed in this study. A questionnaire of 20 questions was applied to the patients to evaluate their knowledge and attitude about COVID-19 and its relationship with dentistry. Results: Two hundred-three women and two hundred-twelve men participated in the study. Thirty three percent of the participants were between the ages of 18-30, and 30.4% were between the ages of 31-40. Most of the participants (87.72%) stated that they did not have COVID-19, while 26.9% were in contact with someone who had COVID-19. In the pandemic process, most dental complaint reported by the participants was gum diseases (55.2%). Loss of taste and smell, and weakness, and joint pain were the most marked COVID-19 symptoms by participants (52.5% and 47.7% respectively). Of the participants 44.6% reported the dentistry devices do not carry the risk of COVID-19 infection transmission. The three methods most frequently used by the participants to reduce the risk of transmission are masks, attention to distance rules, and hand washing. The majority of the participants (88.7%) stated that they paid more attention to their oral and dental health during the restriction period. Conclusion: Individual behaviors and knowledge are important to decrease the spread of COVID-19. Though participants in this study's general knowledge and attitude about COVID-19 are positive, their knowledge about COVID-19 risks in dental treatment is inadequate.