Even though there is a large frequency of mental health issues among adolescents all over the world, there is a lack of knowledge regarding the mental health literacy of this demographic, particularly in economically developing nations. Literacy in mental health is necessary for the early diagnosis and treatment of mental illnesses before they become severe. The objectives of this study are to investigate the mental health literacy of students, the causes of mental illness, the disparities between genders, the reasons for mental disorders, and the variations between grade and causes of mental illnesses. A one-way analysis of variance (ANOVA) and an independent sample t-test were utilized to analyze the data. It was shown that environmental factors were the most significant contributors to mental illness. Furthermore, there was a substantial disparity between the degree of spirituality and the gender of the individual. Moreover, it was demonstrated that there are substantial distinctions between grade and environmental and biological factors. These findings have significant repercussions for educational initiatives that aim to promote students' mental health literacy at the high school level. Among the Vietnamese high school population, there is a demand for programs that teach pupils about mental health literacy. Literacy in mental health serves as the basis for mental health promotion, prevention, and care, with the primary goal of enhancing mental health and its associated outcomes.
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