A unique End-of-Life (EOL) Deep Space View Test (DSVT) was performed on 27 November 2021 for the Advanced Microwave Sounding Unit-A (AMSU-A) and the Microwave Humidity Sounder (MHS) onboard the first EUMETSAT MetOp-A satellite in the deorbiting process. The purpose of this test is to recalibrate the antenna sidelobe, to derive antenna emission, and to quantify the in-orbit asymmetric scan biases of AMSU-A and MHS to, ultimately, improve Near Real-Time (NRT) products for MetOp-B and -C and the entire Fundamental Climate Data Records (FCDR). In this study, MetOp-A AMSU-A and MHS EOL DSVT data on 27 November 2021 have been analyzed. The deep space scene antenna temperatures were first applied for the antenna pattern correction; then, the antenna reflector channel emissivity values were derived from the corrected temperatures. For the MHS, the observed scan-angle-dependent brightness temperatures (BTs) for all channels were well behaved after the antenna pattern correction, except for channel 1. The derived antenna reflector emissivity values from this test are 0.0016, 0.0036, 0.0036, and 0.0019 for channels 1, 3, 4, and 5, respectively. For AMSU-A, the deep space view counts were not homogeneous during the test period, exhibiting large variations in the along-track and cross-track directions, mainly due to the instrument temperature’s rapid change during the test period. The large relative noise in the deep space view observations negatively impacted the data quality and limits the value of this test. The large relative noise may contribute to the different emissivity values derived from the same frequency for channels 9 to 14. We also found unexpected scan-angle-dependent BT after antenna pattern correction for quasi-vertical (QV) channels 1 and 2 when compared to the emission model. Further investigation using a simulation confirmed that channels 1 and 2 are QV channels, as designed.